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Showing 253 to 261 of 261 entries
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Mathematical Modeling of Locoregional Recurrence Caused by Premalignant Lesions Formed Before Initial Treatment.

Frontiers in oncology

Takaki M, Haeno H.
PMID: 34722296
Front Oncol. 2021 Oct 13;11:743328. doi: 10.3389/fonc.2021.743328. eCollection 2021.

Locoregional recurrence after surgery is a major unresolved issue in cancer treatment. Premalignant lesions are considered a cause of cancer recurrence. A study showed that premalignant lesions surrounding the primary tumor drove a high local cancer recurrence rate after...

All-Around Universal and Photoelastic Self-Healing Elastomer with High Toughness and Resilience.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Tolvanen J, Nelo M, Hannu J, Juuti J, Jantunen H.
PMID: 34664423
Adv Sci (Weinh). 2021 Oct 18;e2103235. doi: 10.1002/advs.202103235. Epub 2021 Oct 18.

Ultimately soft electronics seek affordable and high mechanical performance universal self-healing materials that can autonomously heal in harsh environments within short times scales. As of now, such features are not found in a single material. Herein, interpenetrated elastomer network...

Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer.

Cell reports

Dieter SM, Siegl C, Codó PL, Huerta M, Ostermann-Parucha AL, Schulz E, Zowada MK, Martin S, Laaber K, Nowrouzi A, Blatter M, Kreth S, Westermann F, Benner A, Uhrig U, Putzker K, Lewis J, Haegebarth A, Mumberg D, Holton SJ, Weiske J, Toepper LM, Scheib U, Siemeister G, Ball CR, Kuster B, Stoehr G, Hahne H, Johannes S, Lange M, Herbst F, Glimm H.
PMID: 34289372
Cell Rep. 2021 Jul 20;36(3):109394. doi: 10.1016/j.celrep.2021.109394.

Novel treatment options for metastatic colorectal cancer (CRC) are urgently needed to improve patient outcome. Here, we screen a library of non-characterized small molecules against a heterogeneous collection of patient-derived CRC spheroids. By prioritizing compounds with inhibitory activity in...

Survival after aortic root replacement with a stentless xenograft is determined by patient characteristics.

The Journal of thoracic and cardiovascular surgery

Dagnegård HH, Bekke K, Kolseth SM, Glaser N, Wallén C, El-Hamamsy I, Vidisson KO, Lie AS, Valentin JB, Sartipy U, Haaverstad R, Vanky F, Lefebvre L, Gudbjartsson T, Johnsen SP, Søndergaard L, Thyregod GH, Lund JT, Ihlemann N, Smerup MH.
PMID: 34452760
J Thorac Cardiovasc Surg. 2021 Jul 17; doi: 10.1016/j.jtcvs.2021.07.011. Epub 2021 Jul 17.

OBJECTIVES: Our objective was to examine intermediate-term survival and reinterventions in unselected patients, stratified according to indication, who received a Freestyle (Medtronic Inc, Minneapolis, Minn) bioprosthesis as a full aortic root replacement.METHODS: Data from medical records were retrospectively collected...

Reversible cerebral vasoconstriction syndrome: a comprehensive systematic review.

European review for medical and pharmacological sciences

Song TJ, Lee KH, Li H, Kim JY, Chang K, Kim SH, Han KH, Kim BY, Kronbichler A, Ducros A, Koyanagi A, Jacob L, Kim MS, Yon DK, Lee SW, Yang JM, Hong SH, Ghayda RA, Kang JW, Shin JI, Smith L.
PMID: 34002826
Eur Rev Med Pharmacol Sci. 2021 May;25(9):3519-3529. doi: 10.26355/eurrev_202105_25834.

OBJECTIVE: We aimed to analyze clinical characteristics, treatment patterns, and prognosis of patients with reversible cerebral vasoconstriction syndrome (RCVS).MATERIALS AND METHODS: Two investigators independently searched PubMed and EMBASE, and 191 cases were included in this study. Information regarding demographics,...

Allergy education and training for physicians.

The World Allergy Organization journal

Barker S, Daniels L, Chang YS, Chikovani T, DunnGalvin A, Gerdts JD, Gerth Van Wijk R, Gibbs T, Villarreal Gonzalez RV, Guzman-Avilan RI, Hanna H, Hossny E, Kolotilina A, Ortega Martell JA, Pacharn P, de Lira Quezada CE, Sibanda E, Stukus D, Tham EH, Venter C, Gonzalez-Diaz SN, Levin ME, Martin B, Warner JO, Munblit D.
PMID: 34820046
World Allergy Organ J. 2021 Nov 10;14(10):100589. doi: 10.1016/j.waojou.2021.100589. eCollection 2021 Oct.

The increasing prevalence of allergic diseases has placed a significant burden on global healthcare and society as whole. This has necessitated a rapid development of "allergy" as a specialist area. However, as allergy is so common and, for most,...

Long non-coding RNA PVT1 facilitates cell migration and invasion by regulating miR-148a-3p and ROCK1 in breast cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Li HL, Wang CP, Zhang Y, Du JX, Han LH, Yang HY.
PMID: 34859371
Clin Transl Oncol. 2021 Dec 03; doi: 10.1007/s12094-021-02736-0. Epub 2021 Dec 03.

PURPOSE: Breast cancer (BC) is one of the most common malignant tumors for women. The role and potential mechanisms of long non-coding RNA plasmacytoma variant translocation 1 (lncRNA PVT1) were explored in BC cell migration and invasion.METHODS: PVT1, miR-148a-3p...

From stem cells to spiral arteries: A journey through early placental development.

Placenta

James JL, Boss AL, Sun C, Allerkamp HH, Clark AR.
PMID: 34819240
Placenta. 2021 Nov 19; doi: 10.1016/j.placenta.2021.11.004. Epub 2021 Nov 19.

Early placental development lays the foundation of a healthy pregnancy, and numerous tightly regulated processes must occur for the placenta to meet the increasing nutrient and oxygen exchange requirements of the growing fetus later in gestation. Inadequacies in early...

Preoperative sarcopenia and malnutrition are correlated with poor long-term survival after endovascular abdominal aortic aneurysm repair.

Surgery today

Ikeda S, Kodama A, Kawai Y, Tsuruoka T, Sugimoto M, Niimi K, Banno H, Komori K.
PMID: 34477979
Surg Today. 2021 Sep 03; doi: 10.1007/s00595-021-02362-x. Epub 2021 Sep 03.

PURPOSE: Sarcopenia and malnutrition are often used as surrogates for frailty, which is predictive of poor prognosis after surgery. We investigated the effects of sarcopenia and malnutrition on mortality after endovascular aneurysm repair (EVAR).METHODS: The subjects of this study...

Showing 253 to 261 of 261 entries