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Showing 121 to 127 of 127 entries
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An overview of vaccine development for COVID-19.

Therapeutic delivery

Shahcheraghi SH, Ayatollahi J, Aljabali AA, Shastri MD, Shukla SD, Chellappan DK, Jha NK, Anand K, Katari NK, Mehta M, Satija S, Dureja H, Mishra V, Almutary AG, Alnuqaydan AM, Charbe N, Prasher P, Gupta G, Dua K, Lotfi M, Bakshi HA, Tambuwala MM.
PMID: 33624533
Ther Deliv. 2021 Mar;12(3):235-244. doi: 10.4155/tde-2020-0129. Epub 2021 Feb 24.

The COVID-19 pandemic continues to endanger world health and the economy. The causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the COVID-19 pandemic is either herd immunity or widespread availability of an effective vaccine. Multiple...

Ontogeny of plasma cytokine and chemokine concentrations across the first week of human life.

Cytokine

Smolen KK, Plotkin AL, Shannon CP, Idoko OT, Pak J, Darboe A, van Haren S, Amenyogbe N, Tebbutt SJ, Kollmann TR, Kampmann B, Ozonoff A, Levy O, Odumade OA.
PMID: 34597920
Cytokine. 2021 Dec;148:155704. doi: 10.1016/j.cyto.2021.155704. Epub 2021 Sep 28.

INTRODUCTION/BACKGROUND & AIMS: Early life is marked by distinct and rapidly evolving immunity and increased susceptibility to infection. The vulnerability of the newborn reflects development of a complex immune system in the face of rapidly changing demands during the...

Venous thromboembolism and major bleeding in patients with COVID-19: A nationwide population-based cohort study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Dalager-Pedersen M, Lund LC, Mariager T, Winther R, Hellfritzsch M, Larsen TB, Thomsen RW, Johansen NB, Søgaard OS, Nielsen SL, Omland L, Lundbo LF, Israelsen SB, Harboe ZB, Pottegård A, Nielsen H, Bodilsen J.
PMID: 33400771
Clin Infect Dis. 2021 Jan 05; doi: 10.1093/cid/ciab003. Epub 2021 Jan 05.

BACKGROUND: Venous thromboembolism (VTE) is a potentially fatal complication of SARS-CoV-2 infection and thromboprophylaxis should be balanced against risk of bleeding. This study aimed to examine risks of VTE and major bleeding in hospitalized and community-managed SARS-CoV-2 patients compared...

Comorbidity increases the risk of invasive meningococcal disease in adults.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Lundbo LF, Harboe ZB, Sandholdt H, Smith-Hansen L, Valentiner-Branth P, Hoffmann S, Benfield T.
PMID: 34569601
Clin Infect Dis. 2021 Sep 27; doi: 10.1093/cid/ciab856. Epub 2021 Sep 27.

BACKGROUND: Risk of invasive meningococcal disease (IMD) is increased in patients with complement deficiency and HIV infection. Risk associated with comorbidity is not well described.METHODS: Nationwide adult case-control study. Cases for the period 1977-2018 were identified by the national...

Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus.

Journal of neurology

Lauvsnes MB, Zetterberg H, Blennow K, Kvaløy JT, Tjensvoll AB, Maroni S, Beyer MK, Greve OJ, Kvivik I, Alves G, Gøransson LG, Harboe E, Hirohata S, Omdal R.
PMID: 34800169
J Neurol. 2021 Nov 20; doi: 10.1007/s00415-021-10893-z. Epub 2021 Nov 20.

BACKGROUND: Neuropsychiatric manifestations (NP) are common in systemic lupus erythematosus (SLE). However, the pathophysiological mechanisms are not completely understood. Neurofilament light protein (NfL) is part of the neuronal cytoskeleton. Increased NfL concentrations, reflecting neurodegeneration, is observed in cerebrospinal fluid...

Subduction history of the Caribbean from upper-mantle seismic imaging and plate reconstruction.

Nature communications

Braszus B, Goes S, Allen R, Rietbrock A, Collier J, Harmon N, Henstock T, Hicks S, Rychert CA, Maunder B, van Hunen J, Bie L, Blundy J, Cooper G, Davy R, Kendall JM, Macpherson C, Wilkinson J, Wilson M.
PMID: 34244511
Nat Commun. 2021 Jul 09;12(1):4211. doi: 10.1038/s41467-021-24413-0.

The margins of the Caribbean and associated hazards and resources have been shaped by a poorly understood history of subduction. Using new data, we improve teleseismic P-wave imaging of the eastern Caribbean upper mantle and compare identified subducted-plate fragments...

Evolution of Obstructive Lung Function in Advanced Pulmonary Arterial Hypertension.

American journal of respiratory and critical care medicine

Rahaghi FN, Trieu M, Shaikh F, Abtin F, Diaz AA, Liang LL, Barjaktarevic I, Channick RN, San José Estépar R, Washko GR, Saggar R.
PMID: 34555310
Am J Respir Crit Care Med. 2021 Dec 15;204(12):1478-1481. doi: 10.1164/rccm.202105-1169LE.

No abstract available.

Showing 121 to 127 of 127 entries