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Showing 181 to 185 of 185 entries
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Combinatorial Viral Vector-Based and Live Attenuated Vaccines without an Adjuvant to Generate Broader Immune Responses to Effectively Combat Pneumonic Plague.

mBio

Kilgore PB, Sha J, Hendrix EK, Motin VL, Chopra AK.
PMID: 34872353
mBio. 2021 Dec 07;e0322321. doi: 10.1128/mBio.03223-21. Epub 2021 Dec 07.

Mice immunized with a combination of an adenovirus vector (Ad5-YFV) and live-attenuated (LMA)-based vaccines were evaluated for protective efficacy against pneumonic plague. While the Ad5-YFV vaccine harbors a fusion cassette of three genes encoding YscF, F1, and LcrV, LMA...

Genetic Variants in Host Protein Disulfide Isomerase 2 (PDIA2) are Associated with Susceptibility to Chlamydia Trachomatis Infection.

Journal of the Association of Genetic Technologists

Zysk C, Williams S, Chavarria I, Wilson H, Balogun A, Jacobs E, Kaminski R, Foma BT, Johnson J, Lux W, McCoy K, Morales S, Sanchez G, Grubb P, Littlejohn M, Mize R, Moreno J, Pirtle C, Hendrix EC, Bennett KM.
PMID: 33293489
J Assoc Genet Technol. 2020;46(4):244-249.

OBJECTIVES: Objective: Host genetics can influence susceptibility to Chlamydia trachomatis infection. This study examined two genetic variants in human protein disulfide isomerase A2 (PDIA2), a member of a family of protein chaperones that participate in the chlamydial life cycle....

Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia.

Frontiers in oncology

Kolijn PM, Muggen AF, Ljungström V, Agathangelidis A, Wolvers-Tettero ILM, Beverloo HB, Pál K, Hengeveld PJ, Darzentas N, Hendriks RW, van Dongen JJM, Rosenquist R, Langerak AW.
PMID: 34513715
Front Oncol. 2021 Aug 26;11:740083. doi: 10.3389/fonc.2021.740083. eCollection 2021.

Key processes in the onset and evolution of chronic lymphocytic leukemia (CLL) are thought to include chronic (antigenic) activation of mature B cells through the B cell receptor (BcR), signals from the microenvironment, and acquisition of genetic alterations. Here...

Combinatorial Viral Vector-Based and Live Attenuated Vaccines without an Adjuvant to Generate Broader Immune Responses to Effectively Combat Pneumonic Plague.

mBio

Kilgore PB, Sha J, Hendrix EK, Motin VL, Chopra AK.
PMID: 34872353
mBio. 2021 Dec 07;e0322321. doi: 10.1128/mBio.03223-21. Epub 2021 Dec 07.

Mice immunized with a combination of an adenovirus vector (Ad5-YFV) and live-attenuated (LMA)-based vaccines were evaluated for protective efficacy against pneumonic plague. While the Ad5-YFV vaccine harbors a fusion cassette of three genes encoding YscF, F1, and LcrV, LMA...

Multiparametric magnetic resonance imaging to characterize cabotegravir long-acting formulation depot kinetics in healthy adult volunteers.

British journal of clinical pharmacology

Jucker BM, Fuchs EJ, Lee S, Damian V, Galette P, Janiczek R, Macura KJ, Jacobs MA, Weld ED, Solaiyappan M, D'Amico R, Shaik JS, Bakshi K, Han K, Ford S, Margolis D, Spreen W, Gupta MK, Hendrix CW, Patel P.
PMID: 34240449
Br J Clin Pharmacol. 2021 Jul 08; doi: 10.1111/bcp.14977. Epub 2021 Jul 08.

AIM: Cabotegravir long-acting (LA) intramuscular (IM) injection is being investigated for HIV preexposure prophylaxis due to its potent antiretroviral activity and infrequent dosing requirement. A subset of healthy adult volunteers participating in a Phase I study assessing cabotegravir tissue...

Showing 181 to 185 of 185 entries