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Showing 25 to 36 of 88 entries
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Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5-HT3A receptors due to the action of flavonoids.

Frontiers in pharmacology

Herbrechter R, Ziemba PM, Hoffmann KM, Hatt H, Werner M, Gisselmann G.
PMID: 26191003
Front Pharmacol. 2015 Jul 03;6:130. doi: 10.3389/fphar.2015.00130. eCollection 2015.

The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT3 receptor antagonism, due to the involvement of these receptors in such pathophysiological processes. E.g., setrons, specific 5-HT3...

Facile one-pot fabrication of hollow porous silica nanoparticles.

Chemistry (Weinheim an der Bergstrasse, Germany)

Abdelaal HM, Zawrah MF, Harbrecht B.
PMID: 24327262
Chemistry. 2014 Jan 13;20(3):673-7. doi: 10.1002/chem.201303656. Epub 2013 Dec 10.

A method for the fabrication of hollow silica nanospheres, a facile one-pot hydrothermal route, is described. Heating of an aqueous solution of water glass and D-glucose to 180 °C for 24 h affords-as indicated by transmission electron microscopy-a nanospherical...

Site preference and ordering induced by Au substitution in the γ-brass related complex Au-Cr-Zn phases.

Inorganic chemistry

Jana PP, Henderson R, Harbrecht B, Lidin S.
PMID: 23642175
Inorg Chem. 2013 May 06;52(9):4812-8. doi: 10.1021/ic302244e. Epub 2013 Apr 22.

The crystal chemistry of the ternary Au-Cr-Zn alloy was studied by means of synthesis, single crystal X-ray diffraction, and electron structure calculations. While the compound CrZn(∼17) represents the binary end-point of the homogeneity range, the inclusion of Au proves...

Pretransplant Intensive Care Unit Management and Selection of Grade 3 Acute-on-Chronic Liver Failure Transplant Candidates.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Michard B, Artzner T, Deridder M, Besch C, Addeo P, Castelain V, Guillot M, Harlay ML, Herbrecht JE, Janssen Langenstein R, Schenck M, Bachellier P, Schneider F, Faitot F.
PMID: 34431204
Liver Transpl. 2022 Jan;28(1):17-26. doi: 10.1002/lt.26280. Epub 2021 Oct 07.

The aim of this study is to report on the liver transplantation (LT) activity and posttransplant outcome, over time, of patients with grade 3 acute-on-chronic liver failure (ACLF-3) in a single transplant center performing a large number of LTs...

Forcing substitution of tantalum by copper in 1T-TaS.

Journal of physics. Condensed matter : an Institute of Physics journal

Sachs M, Bohnen K, Conrad M, Klein BP, Krug CK, Pietzonka C, Schmid M, Zörb S, Gottfried JM, Harbrecht B.
PMID: 30102241
J Phys Condens Matter. 2018 Sep 26;30(38):385501. doi: 10.1088/1361-648X/aad9c6. Epub 2018 Aug 13.

We investigated the compound 1T-Cu

Pretransplant Intensive Care Unit Management and Selection of Grade 3 Acute-on-Chronic Liver Failure Transplant Candidates.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Michard B, Artzner T, Deridder M, Besch C, Addeo P, Castelain V, Guillot M, Harlay ML, Herbrecht JE, Janssen Langenstein R, Schenck M, Bachellier P, Schneider F, Faitot F.
PMID: 34431204
Liver Transpl. 2022 Jan;28(1):17-26. doi: 10.1002/lt.26280. Epub 2021 Oct 07.

The aim of this study is to report on the liver transplantation (LT) activity and posttransplant outcome, over time, of patients with grade 3 acute-on-chronic liver failure (ACLF-3) in a single transplant center performing a large number of LTs...

The Role of Kynurenines in Cognitive Dysfunction in Bipolar Disorder.

Neuropsychobiology

Hebbrecht K, Morrens M, Giltay EJ, van Nuijs ALN, Sabbe B, van den Ameele S.
PMID: 34883494
Neuropsychobiology. 2021 Dec 09;1-8. doi: 10.1159/000520152. Epub 2021 Dec 09.

INTRODUCTION: Chronic low-grade inflammation is suggested to play a pathophysiological role in bipolar disorder (BD) and its related cognitive dysfunctions. Although kynurenine (KYN) pathway metabolites are key inflammatory mediators, studies investigating the association between KYN metabolism and cognition in...

Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020.

Emerging infectious diseases

Kaeuffer C, Baldacini M, Ruge T, Ruch Y, Zhu YJ, De Cian M, Philouze G, Bachellier P, Denis J, Lefebvre N, Schneider F, Hansmann Y, Letscher-Bru V, Herbrecht R, Sabou M, Danion F.
PMID: 34932452
Emerg Infect Dis. 2022 Jan;28(1):29-34. doi: 10.3201/eid2801.211543.

Rare fungal pathogens are emerging as agents of invasive fungal infections. We analyzed 13 cases of fungal infections caused by Kazachstania (Arxiozyma) spp. in Strasbourg University Hospital, Strasbourg, France. Among the cases, 4 patients had proven fungal disease (3...

Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020.

Emerging infectious diseases

Kaeuffer C, Baldacini M, Ruge T, Ruch Y, Zhu YJ, De Cian M, Philouze G, Bachellier P, Denis J, Lefebvre N, Schneider F, Hansmann Y, Letscher-Bru V, Herbrecht R, Sabou M, Danion F.
PMID: 34932452
Emerg Infect Dis. 2022 Jan;28(1):29-34. doi: 10.3201/eid2801.211543.

Rare fungal pathogens are emerging as agents of invasive fungal infections. We analyzed 13 cases of fungal infections caused by Kazachstania (Arxiozyma) spp. in Strasbourg University Hospital, Strasbourg, France. Among the cases, 4 patients had proven fungal disease (3...

What to expect? Injury patterns of Electric-Scooter accidents over a period of one year - A prospective monocentric study at a Level 1 Trauma Center.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Harbrecht A, Hackl M, Leschinger T, Uschok S, Wegmann K, Eysel P, Müller LP.
PMID: 34061254
Eur J Orthop Surg Traumatol. 2021 Jun 01; doi: 10.1007/s00590-021-03014-z. Epub 2021 Jun 01.

PURPOSE: E-scooters are a new type of urban transportation utilized in Germany since June 2019, primarily in larger cities in the context of sharing offers. Such electrically operated standing scooters can be driven at a maximum speed of 20...

Idiosyncratic Drug-Induced Severe Neutropenia and Agranulocytosis in Elderly Patients (≥75 years): A Monocentric Cohort Study of 61 Cases.

Drugs - real world outcomes

Mourot-Cottet R, Maloisel F, Séverac F, Keller O, Vogel T, Tebacher M, Weber JC, Kaltenbach G, Gottenberg JE, Goichot B, Sibilia J, Korganow AS, Herbrecht R, Andrès E.
PMID: 27747601
Drugs Real World Outcomes. 2016 Dec;3(4):393-399. doi: 10.1007/s40801-016-0091-4.

BACKGROUND: Little data is currently available in the literature on neutropenia and agranulocytosis in the elderly, and, to our knowledge, idiosyncratic drug-induced agranulocytosis is particularly poorly covered, or not at all.OBJECTIVE: We herein describe the clinical picture and outcome...

Immunosuppression in patients with Grade 3 Acute-On-Chronic Liver Failure at transplantation: A practice analysis study.

Clinical transplantation

Faitot F, Artzner T, Michard B, Besch C, Schenck M, Herbrecht JE, Langenstein RJ, Maestraggi Q, Guillot M, Harlay ML, Castelain V, Addeo P, Ellero B, Woehl-Jaegle ML, Serfaty L, Bachellier P, Schneider F, Study Group OBOTSLTS.
PMID: 34974638
Clin Transplant. 2022 Jan 02;e14580. doi: 10.1111/ctr.14580. Epub 2022 Jan 02.

Transplantation for patients with acute-on-chronic liver failure grade 3 (ACLF3) has encouraging results with one-year-survival of 80-90%. These patients with multiple organ failure meet the conditions for serious alterations of drug metabolism and increased toxicity. The goal of this...

Showing 25 to 36 of 88 entries