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Showing 13 to 24 of 24 entries
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The Hippo pathway in disease and therapy: cancer and beyond.

Clinical and translational medicine

Gomez M, Gomez V, Hergovich A.
PMID: 25097725
Clin Transl Med. 2014 Jul 10;3:22. doi: 10.1186/2001-1326-3-22. eCollection 2014.

The Hippo tumour suppressor pathway co-ordinates cell proliferation, cell death and cell differentiation to regulate tissue growth control. In mammals, a conserved core Hippo signalling module receives signal inputs on different levels to ensure the proper regulation of YAP/TAZ...

Current Trends in Forensic Paint Examination.

Forensic science review

Ryland SG, Jergovich TA, Kirkbride KP.
PMID: 26247225
Forensic Sci Rev. 2006 Jul;18(2):97-117.

Paints and coatings have been recognized as a useful type of forensic evidence for several decades. During this time the materials themselves, the analytical methods used to examine them, and the legal environment surrounding the use of scientific evidence...

Correction: Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation.

Oncotarget

Bettoun A, Joffre C, Zago G, Surdez D, Vallerand D, Gundogdu R, Sharif AAD, Gomez M, Cascone I, Meunier B, White MA, Codogno P, Parrini MC, Camonis JH, Hergovich A.
PMID: 29854321
Oncotarget. 2018 Apr 27;9(32):22870. doi: 10.18632/oncotarget.25335. eCollection 2018 Apr 27.

[This corrects the article DOI: 10.18632/oncotarget.9875.].

Essentially perturbative quantities in the Kondo model.

Physical review. B, Condensed matter

Berkovich A, Lowenstein JH.
PMID: 9936868
Phys Rev B Condens Matter. 1985 Dec 01;32(11):7263-7272. doi: 10.1103/physrevb.32.7263.

No abstract available.

Micellar polymerization: Computer simulations by dissipative particle dynamics.

Journal of computational chemistry

Shupanov R, Chertovich A, Kos P.
PMID: 29464743
J Comput Chem. 2018 Jul 15;39(19):1275-1284. doi: 10.1002/jcc.25194. Epub 2018 Feb 21.

Nowadays, micellar polymerization is widely used in different fields of industry and research, including modern living polymerization technique. However, this process has many variables and there is no comprehensive model to describe all features. This research presents simulation methodology...

TAZ-mediated crosstalk between Wnt and Hippo signaling.

Developmental cell

Hergovich A, Hemmings BA.
PMID: 20412766
Dev Cell. 2010 Apr 20;18(4):508-9. doi: 10.1016/j.devcel.2010.04.003.

Previously, research addressing Hippo signaling focused on the inactivation of the proto-oncoproteins TAZ and YAP caused by the sequestration of supposedly inactive phospho-TAZ/YAP in the cytoplasm. In this issue of Developmental Cell, the Attisano laboratory now shows that cytoplasmic...

The Roles of NDR Protein Kinases in Hippo Signalling.

Genes

Hergovich A.
PMID: 27213455
Genes (Basel). 2016 May 18;7(5). doi: 10.3390/genes7050021.

The Hippo tumour suppressor pathway has emerged as a critical regulator of tissue growth through controlling cellular processes such as cell proliferation, death, differentiation and stemness. Traditionally, the core cassette of the Hippo pathway includes the MST1/2 protein kinases,...

Magic and Misdirection: The Influence of Social Cues on the Allocation of Visual Attention While Watching a Cups-and-Balls Routine.

Frontiers in psychology

Hergovich A, Oberfichtner B.
PMID: 27303327
Front Psychol. 2016 May 31;7:761. doi: 10.3389/fpsyg.2016.00761. eCollection 2016.

In recent years, a body of research that regards the scientific study of magic performances as a promising method of investigating psychological phenomena in an ecologically valid setting has emerged. Seemingly contradictory findings concerning the ability of social cues...

Kinetic mechanisms of crumpled globule formation.

Soft matter

Petrov A, Kos P, Chertovich A.
PMID: 31999294
Soft Matter. 2020 Feb 26;16(8):2045-2054. doi: 10.1039/c9sm01874c.

A homopolymer chain with beads forming pairwise reversible bonds is a well-known model in polymer physics. We studied the kinetics of homopolymer chain collapse, which was induced by pairwise reversible bond formation. We compared the kinetic mechanism of this...

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Cell

Li H, van der Leun AM, Yofe I, Lubling Y, Gelbard-Solodkin D, van Akkooi ACJ, van den Braber M, Rozeman EA, Haanen JBAG, Blank CU, Horlings HM, David E, Baran Y, Bercovich A, Lifshitz A, Schumacher TN, Tanay A, Amit I.
PMID: 32359441
Cell. 2020 Apr 30;181(3):747. doi: 10.1016/j.cell.2020.04.017.

No abstract available.

hMOB2 deficiency impairs homologous recombination-mediated DNA repair and sensitises cancer cells to PARP inhibitors.

Cellular signalling

Gundogdu R, Erdogan MK, Ditsiou A, Spanswick V, Garcia-Gomez JJ, Hartley JA, Esashi F, Hergovich A, Gomez V.
PMID: 34363951
Cell Signal. 2021 Nov;87:110106. doi: 10.1016/j.cellsig.2021.110106. Epub 2021 Aug 05.

Monopolar spindle-one binder (MOBs) proteins are evolutionarily conserved and contribute to various cellular signalling pathways. Recently, we reported that hMOB2 functions in preventing the accumulation of endogenous DNA damage and a subsequent p53/p21-dependent G1/S cell cycle arrest in untransformed...

Diagnosis and management of Intratyroid Ectopic Thymus.

Andes pediatrica : revista Chilena de pediatria

Gazek N, Dujovne N, Ayarzábal V, Teplisky D, Herzovich V, Felipe L.
PMID: 34479247
Andes Pediatr. 2021 Jun;92(3):406-410. doi: 10.32641/andespediatr.v92i3.3439.

INTRODUCTION: Intrathyroidal ectopic thymus (IET) is a rare benign condition caused by the aberrant thymic migra tion during embryogenesis. It is usually incidentally diagnosed as a thyroid nodule.OBJECTIVE: To report the intrathyroidal location of ectopic thymic tissue and to...

Showing 13 to 24 of 24 entries