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Showing 109 to 118 of 118 entries
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Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.

ACS medicinal chemistry letters

Kallander LS, Washburn D, Hilfiker MA, Eidam HS, Lawhorn BG, Prendergast J, Fox R, Dowdell S, Manns S, Hoang T, Zhao S, Ye G, Hammond M, Holt DA, Roethke T, Hong X, Reid RA, Gampe R, Zhang H, Diaz E, Rendina AR, Quinn AM, Willette B.
PMID: 30034610
ACS Med Chem Lett. 2018 Jul 02;9(7):736-740. doi: 10.1021/acsmedchemlett.8b00173. eCollection 2018 Jul 12.

Bone Morphogenetic Protein 1 (BMP1) inhibition is a potential method for treating fibrosis because BMP1, a member of the zinc metalloprotease family, is required to convert pro-collagen to collagen. A novel class of reverse hydroxamate BMP1 inhibitors was discovered,...

Role of Non-Invasive Respiratory Supports in COVID-19 Acute Respiratory Failure Patients with Do Not Intubate Orders.

Journal of clinical medicine

Medrinal C, Gillet A, Boujibar F, Dugernier J, Zwahlen M, Lamia B, Girault C, Creteur J, Fellrath JM, Haesler L, Lagache L, Goubert L, Artaud Macari E, Taton O, Gouin P, Leduc D, Van Hove O, Norrenberg M, Prieur G, Combret Y, Correvon N, Hilfiker R, Contal O.
PMID: 34202895
J Clin Med. 2021 Jun 24;10(13). doi: 10.3390/jcm10132783.

The current gold-standard treatment for COVID-19-related hypoxemic respiratory failure is invasive mechanical ventilation. However, do not intubate orders (DNI), prevent the use of this treatment in some cases. The aim of this study was to evaluate if non-invasive ventilatory...

Systematic Review of Incidence Studies of Pneumonia in Persons with Spinal Cord Injury.

Journal of clinical medicine

Raab AM, Mueller G, Elsig S, Gandevia SC, Zwahlen M, Hopman MTE, Hilfiker R.
PMID: 35011951
J Clin Med. 2021 Dec 31;11(1). doi: 10.3390/jcm11010211.

Pneumonia continues to complicate the course of spinal cord injury (SCI). Currently, clinicians and policy-makers are faced with only limited numbers of pneumonia incidence in the literature. A systematic review of the literature was undertaken to provide an objective...

How physically active are people with stroke in physiotherapy sessions aimed at improving motor function? A systematic review.

Stroke research and treatment

Kaur G, English C, Hillier S.
PMID: 22567542
Stroke Res Treat. 2012;2012:820673. doi: 10.1155/2012/820673. Epub 2012 Apr 10.

Background. Targeted physical activity drives functional recovery after stroke. This review aimed to determine the amount of time stroke survivors spend physically active during physiotherapy sessions. Summary of Review. A systematic search was conducted to identify published studies that...

COVID-19 Pandemic Impact on Care for Stroke in Australia: Emerging Evidence From the Australian Stroke Clinical Registry.

Frontiers in neurology

Cadilhac DA, Kim J, Tod EK, Morrison JL, Breen SJ, Jaques K, Grimley R, Jones B, Cloud GC, Kleinig T, Hillier S, Castley H, Lindley RI, Lannin NA, Middleton S, Yan B, Hill K, Clissold BB, Mitchell PJ, Anderson CS, Faux SG, Campbell BCV.
PMID: 33716925
Front Neurol. 2021 Feb 26;12:621495. doi: 10.3389/fneur.2021.621495. eCollection 2021.

We present information on acute stroke care for the first wave of the COVID-19 pandemic in Australia using data from the Australian Stroke Clinical Registry (AuSCR). The first case of COVID-19 in Australia was recorded in late January 2020...

Rab GTPases in Parkinson's disease: a primer.

Essays in biochemistry

Lara Ordóñez AJ, Fasiczka R, Naaldijk Y, Hilfiker S.
PMID: 34414419
Essays Biochem. 2021 Dec 22;65(7):961-974. doi: 10.1042/EBC20210016.

Parkinson's disease is a prominent and debilitating movement disorder characterized by the death of vulnerable neurons which share a set of structural and physiological properties. Over the recent years, increasing evidence indicates that Rab GTPases can directly as well...

Early Welsh cervical screening programme learning as a consequence of the coronavirus pandemic.

Cytopathology : official journal of the British Society for Clinical Cytology

Leeson S, Evered A, Powell G, Lilly K, Singh N, Hillier S, Dunk L.
PMID: 34935223
Cytopathology. 2021 Dec 21; doi: 10.1111/cyt.13091. Epub 2021 Dec 21.

BACKGROUND: The coronavirus pandemic has had a profound impact on the cervical screening programme in Wales for the eligible women, sample takers and laboratory and colposcopy services.AIMS: To explore what changes due the pandemic have adversely affected screening outcomes...

Flatline on the alternate vector…Is this subcutaneous implantable cardiac defibrillator lead fractured?.

HeartRhythm case reports

O'Neill L, Gillis K, Wielandts JY, Hilfiker G, Knecht S, Duytschaever M, Tavernier R, Le Polain De Waroux JB.
PMID: 34820275
HeartRhythm Case Rep. 2021 Sep 01;7(11):758-761. doi: 10.1016/j.hrcr.2021.08.008. eCollection 2021 Nov.

No abstract available.

Bariatric Surgery: Consequences on Functional Capacities in Patients With Obesity.

Frontiers in endocrinology

Reinmann A, Gafner SC, Hilfiker R, Bruyneel AV, Pataky Z, Allet L.
PMID: 33868175
Front Endocrinol (Lausanne). 2021 Apr 01;12:646283. doi: 10.3389/fendo.2021.646283. eCollection 2021.

INTRODUCTION: Bariatric surgery leads to loss of fat and fat-free mass (FFM). To preserve FFM it is recommended that weight loss interventions are accompanied by physical activity. However, it remains unknown if functional capacities spontaneously improve after a substantial...

The Effects of Dynamic and Static Emotional Facial Expressions of Humans and Their Avatars on the EEG: An ERP and ERD/ERS Study.

Frontiers in neuroscience

Sollfrank T, Kohnen O, Hilfiker P, Kegel LC, Jokeit H, Brugger P, Loertscher ML, Rey A, Mersch D, Sternagel J, Weber M, Grunwald T.
PMID: 33967681
Front Neurosci. 2021 Apr 22;15:651044. doi: 10.3389/fnins.2021.651044. eCollection 2021.

This study aimed to examine whether the cortical processing of emotional faces is modulated by the computerization of face stimuli ("avatars") in a group of 25 healthy participants. Subjects were passively viewing 128 static and dynamic facial expressions of...

Showing 109 to 118 of 118 entries