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Showing 601 to 612 of 612 entries
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Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation.

Cell death & disease

Soroosh A, Fang K, Hoffman JM, Law IKM, Videlock E, Lokhandwala ZA, Zhao JJ, Hamidi S, Padua DM, Frey MR, Pothoulakis C, Rankin CR.
PMID: 34923573
Cell Death Dis. 2021 Dec 18;13(1):8. doi: 10.1038/s41419-021-04463-4.

While apoptosis plays a significant role in intestinal homeostasis, it can also be pathogenic if overactive during recovery from inflammation. We recently reported that microRNA-24-3p (miR-24-3p) is elevated in the colonic epithelium of ulcerative colitis patients during active inflammation,...

Sex Differences in the Human Brain Transcriptome of Cases With Schizophrenia.

Biological psychiatry

Hoffman GE, Ma Y, Montgomery KS, Bendl J, Jaiswal MK, Kozlenkov A, Peters MA, Dracheva S, Fullard JF, Chess A, Devlin B, Sieberts SK, Roussos P.
PMID: 34154796
Biol Psychiatry. 2022 Jan 01;91(1):92-101. doi: 10.1016/j.biopsych.2021.03.020. Epub 2021 Mar 25.

BACKGROUND: While schizophrenia differs between males and females in the age of onset, symptomatology, and disease course, the molecular mechanisms underlying these differences remain uncharacterized.METHODS: To address questions about the sex-specific effects of schizophrenia, we performed a large-scale transcriptome...

Psychological Health, Well-Being, and the Mind-Heart-Body Connection: A Scientific Statement From the American Heart Association.

Circulation

Levine GN, Cohen BE, Commodore-Mensah Y, Fleury J, Huffman JC, Khalid U, Labarthe DR, Lavretsky H, Michos ED, Spatz ES, Kubzansky LD.
PMID: 33486973
Circulation. 2021 Mar 09;143(10):e763-e783. doi: 10.1161/CIR.0000000000000947. Epub 2021 Jan 25.

As clinicians delivering health care, we are very good at treating disease but often not as good at treating the person. The focus of our attention has been on the specific physical condition rather than the patient as a...

Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation.

Cell death & disease

Soroosh A, Fang K, Hoffman JM, Law IKM, Videlock E, Lokhandwala ZA, Zhao JJ, Hamidi S, Padua DM, Frey MR, Pothoulakis C, Rankin CR.
PMID: 34923573
Cell Death Dis. 2021 Dec 18;13(1):8. doi: 10.1038/s41419-021-04463-4.

While apoptosis plays a significant role in intestinal homeostasis, it can also be pathogenic if overactive during recovery from inflammation. We recently reported that microRNA-24-3p (miR-24-3p) is elevated in the colonic epithelium of ulcerative colitis patients during active inflammation,...

Predictors of completion and response to a psychological intervention to promote health behavior adherence in heart failure.

International journal of psychiatry in medicine

Celano CM, Golden J, Healy BC, Longley RM, Huffman JC.
PMID: 33461359
Int J Psychiatry Med. 2022 Jan;57(1):21-34. doi: 10.1177/0091217421989830. Epub 2021 Jan 18.

OBJECTIVE: Most individuals with heart failure (HF) struggle to adhere to one or more health behaviors, and interventions to promote adherence are time-intensive and costly. In this analysis, we examined the predictors of engagement and response related to a...

"What Does it Mean to be Trauma-Informed?": A Mixed-Methods Study of a Trauma-Informed Community Initiative.

Journal of child and family studies

Champine RB, Hoffman EE, Matlin SL, Strambler MJ, Tebes JK.
PMID: 35018088
J Child Fam Stud. 2022 Jan 07;1-14. doi: 10.1007/s10826-021-02195-9. Epub 2022 Jan 07.

Trauma during childhood has the potential to adversely affect one's physical, cognitive, emotional, and social development across the life span. However, the adverse effects of trauma can be prevented and mitigated through holistic services and supports that are trauma-informed....

Passively sensing SARS-CoV-2 RNA in public transit buses.

The Science of the total environment

Hoffman JS, Hirano M, Panpradist N, Breda J, Ruth P, Xu Y, Lester J, Nguyen BH, Ceze L, Patel SN.
PMID: 35007574
Sci Total Environ. 2022 Jan 07;152790. doi: 10.1016/j.scitotenv.2021.152790. Epub 2022 Jan 07.

Affordably tracking the transmission of respiratory infectious diseases in urban transport infrastructures can inform individuals about potential exposure to diseases and guide public policymakers to prepare timely responses based on geographical transmission in different areas in the city. Towards...

Untapped research opportunities in China: promising future avenues and potential concerns for aging companion animals.

GeroScience

Hoffman JM, Song S, Brugger K, Valencak TG.
PMID: 34427857
Geroscience. 2021 Aug 24; doi: 10.1007/s11357-021-00433-y. Epub 2021 Aug 24.

Companion animals have recently been proposed as ideal translational models of human aging due to their shared susceptibility for certain diseases, similar environments, and sophisticated veterinary medicine diagnostics, all of which are not possible in rodent laboratory models. Here,...

Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation.

Cell death & disease

Soroosh A, Fang K, Hoffman JM, Law IKM, Videlock E, Lokhandwala ZA, Zhao JJ, Hamidi S, Padua DM, Frey MR, Pothoulakis C, Rankin CR.
PMID: 34923573
Cell Death Dis. 2021 Dec 18;13(1):8. doi: 10.1038/s41419-021-04463-4.

While apoptosis plays a significant role in intestinal homeostasis, it can also be pathogenic if overactive during recovery from inflammation. We recently reported that microRNA-24-3p (miR-24-3p) is elevated in the colonic epithelium of ulcerative colitis patients during active inflammation,...

Relationship Between Diabetes, Stress, and Self-Management to Inform Chronic Disease Product Development: Retrospective Cross-Sectional Study.

JMIR diabetes

Yu JS, Xu T, James RA, Lu W, Hoffman JE.
PMID: 33355538
JMIR Diabetes. 2020 Dec 23;5(4):e20888. doi: 10.2196/20888.

BACKGROUND: Technology is rapidly advancing our understanding of how people with diabetes mellitus experience stress.OBJECTIVE: The aim of this study was to explore the relationship between stress and sequelae of diabetes mellitus within a unique data set composed of...

Intraoperative Hypotension in a Patient with Antithrombin Deficiency, Bilateral Pulmonary Emboli, and Cefazolin Allergy.

Cureus

Muncey AR, Aldawoodi NN, Chitneni A, Hoffman JP, Escher AR.
PMID: 33665061
Cureus. 2021 Mar 02;13(3):e13653. doi: 10.7759/cureus.13653.

In medicine, the search for a clear answer can at times be elusive. However, this does not necessarily preclude the administration of intelligent and thoughtful therapeutic treatments. Here, we describe a complicated emergent event of severe hypotension and near-arrest...

Imaging the impact of single oxygen atoms on superconducting Bi(2+y)Sr(2-y)CaCu2O(8+x).

Science (New York, N.Y.)

Zeljkovic I, Xu Z, Wen J, Gu G, Markiewicz RS, Hoffman JE.
PMID: 22822144
Science. 2012 Jul 20;337(6092):320-3. doi: 10.1126/science.1218648.

High-temperature cuprate superconductors display unexpected nanoscale inhomogeneity in essential properties such as pseudogap energy, Fermi surface, and even superconducting critical temperature. Theoretical explanations for this inhomogeneity have ranged from chemical disorder to spontaneous electronic phase separation. We extend the...

Showing 601 to 612 of 612 entries