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Showing 229 to 238 of 238 entries
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Case of anti-nuclear matrix protein 2 antibody-positive juvenile dermatomyositis preceded by linear cutaneous lupus erythematosus on the face.

The Journal of dermatology

Miyahara H, Okiyama N, Okune M, Konishi R, Miyamoto M, Hara M, Iwabuchi A, Takada H, Nishino I, Nomura T.
PMID: 34626009
J Dermatol. 2021 Oct 08; doi: 10.1111/1346-8138.16192. Epub 2021 Oct 08.

No abstract available.

Case of anti-nuclear matrix protein 2 antibody-positive juvenile dermatomyositis preceded by linear cutaneous lupus erythematosus on the face.

The Journal of dermatology

Miyahara H, Okiyama N, Okune M, Konishi R, Miyamoto M, Hara M, Iwabuchi A, Takada H, Nishino I, Nomura T.
PMID: 34626009
J Dermatol. 2022 Jan;49(1):e18-e19. doi: 10.1111/1346-8138.16192. Epub 2021 Oct 08.

No abstract available.

Toward the Creation of Induced Pluripotent Small (iPS) Molecules: Establishment of a Modular Synthetic Strategy for the Heronamide C-type Polyene Macrolactams and Their Conformational and Reactivity Analysis.

The Journal of organic chemistry

Kanoh N, Terajima Y, Tanaka S, Terashima R, Nishiyama H, Nagasawa S, Sasano Y, Iwabuchi Y, Nishimura S, Kakeya H.
PMID: 34797655
J Org Chem. 2021 Dec 03;86(23):16231-16248. doi: 10.1021/acs.joc.1c01760. Epub 2021 Nov 19.

A highly modular synthetic strategy for the heronamide C-type polyene macrolactams was established by synthesizing 8-deoxyheronamide C (

FE65 in breast cancer and its clinicopathological significance.

Breast cancer (Tokyo, Japan)

Xu J, Iwabuchi E, Miki Y, Kanai A, Ishida T, Sasano H.
PMID: 34498219
Breast Cancer. 2022 Jan;29(1):144-155. doi: 10.1007/s12282-021-01291-4. Epub 2021 Sep 08.

BACKGROUND: Transcription coregulator adapter protein FE65 is well known to play pivotal roles in pathogenesis of Alzheimer's disease by regulating amyloid precursor protein (APP) expression and processing. APP was recently reported to be also involved in development of human...

Natural Killer T Cells Are Involved in Atherosclerotic Plaque Instability in Apolipoprotein-E Knockout Mice.

International journal of molecular sciences

Ohmura Y, Ishimori N, Saito A, Yokota T, Horii S, Tokuhara S, Iwabuchi K, Tsutsui H.
PMID: 34830332
Int J Mol Sci. 2021 Nov 18;22(22). doi: 10.3390/ijms222212451.

The infiltration and activation of macrophages as well as lymphocytes within atherosclerotic lesion contribute to the pathogenesis of plaque rupture. We have demonstrated that invariant natural killer T (iNKT) cells, a unique subset of T lymphocytes that recognize glycolipid...

A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins.

Biochemical pharmacology

Segawa R, Takeda H, Yokoyama T, Ishida M, Miyata C, Saito T, Ishihara R, Nakagita T, Sasano Y, Kanoh N, Iwabuchi Y, Mizuguchi M, Hiratsuka M, Hirasawa N.
PMID: 34757034
Biochem Pharmacol. 2021 Dec;194:114819. doi: 10.1016/j.bcp.2021.114819. Epub 2021 Oct 30.

Although treatments for allergic diseases have improved, side effects and treatment resistance remain as challenges. New therapeutic drugs for allergic diseases are urgently required. Thymic stromal lymphopoietin (TSLP) is a cytokine target for prevention and treatment of allergic diseases....

CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) update 2022.

Cardiovascular intervention and therapeutics

Ozaki Y, Hara H, Onuma Y, Katagiri Y, Amano T, Kobayashi Y, Muramatsu T, Ishii H, Kozuma K, Tanaka N, Matsuo H, Uemura S, Kadota K, Hikichi Y, Tsujita K, Ako J, Nakagawa Y, Morino Y, Hamanaka I, Shiode N, Shite J, Honye J, Matsubara T, Kawai K, Igarashi Y, Okamura A, Ogawa T, Shibata Y, Tsuji T, Yajima J, Iwabuchi K, Komatsu N, Sugano T, Yamaki M, Yamada S, Hirase H, Miyashita Y, Yoshimachi F, Kobayashi M, Aoki J, Oda H, Katahira Y, Ueda K, Nishino M, Nakao K, Michishita I, Ueno T, Inohara T, Kohsaka S, Ismail TF, Serruys PW, Nakamura M, Yokoi H, Ikari Y.
PMID: 35018605
Cardiovasc Interv Ther. 2022 Jan 12; doi: 10.1007/s12928-021-00829-9. Epub 2022 Jan 12.

Primary Percutaneous Coronary Intervention (PCI) has significantly contributed to reducing the mortality of patients with ST-segment elevation myocardial infarction (STEMI) even in cardiogenic shock and is now the standard of care in most of Japanese institutions. The Task Force...

A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins.

Biochemical pharmacology

Segawa R, Takeda H, Yokoyama T, Ishida M, Miyata C, Saito T, Ishihara R, Nakagita T, Sasano Y, Kanoh N, Iwabuchi Y, Mizuguchi M, Hiratsuka M, Hirasawa N.
PMID: 34757034
Biochem Pharmacol. 2021 Dec;194:114819. doi: 10.1016/j.bcp.2021.114819. Epub 2021 Oct 30.

Although treatments for allergic diseases have improved, side effects and treatment resistance remain as challenges. New therapeutic drugs for allergic diseases are urgently required. Thymic stromal lymphopoietin (TSLP) is a cytokine target for prevention and treatment of allergic diseases....

Natural Killer Cell Group 7 Sequence in Cytotoxic Cells Optimizes Exocytosis of Lytic Granules Essential for the Perforin-Dependent, but Not Fas Ligand-Dependent, Cytolytic Pathway.

ImmunoHorizons

Morikawa Y, Murakami M, Kondo H, Nemoto N, Iwabuchi K, Eshima K.
PMID: 33911019
Immunohorizons. 2021 Apr 28;5(4):234-245. doi: 10.4049/immunohorizons.2100029.

Cytotoxic cells, such as CD8

Development of an immunochromatographic test for the detection of Mycoplasma pneumoniae GroES antigen.

Journal of microbiological methods

Matsui H, Sugimura M, Inoue-Tsuda M, Iwabuchi K, Hanaki H.
PMID: 34744002
J Microbiol Methods. 2021 Dec;191:106359. doi: 10.1016/j.mimet.2021.106359. Epub 2021 Oct 30.

Mycoplasma pneumoniae frequently causes community-acquired pneumonia in children; β-lactam antibiotics are ineffective against this bacterium because of its lack of a cell wall. Hence, a rapid and simple detection method is required to ensure appropriate treatment. In this study,...

Showing 229 to 238 of 238 entries