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Showing 5881 to 5889 of 5889 entries
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Exosomal miR-125b Exerts Anti-Metastatic Properties and Predicts Early Metastasis of Hepatocellular Carcinoma.

Frontiers in oncology

Kim HS, Kim JS, Park NR, Nam H, Sung PS, Bae SH, Choi JY, Yoon SK, Hur W, Jang JW.
PMID: 34386414
Front Oncol. 2021 Jul 27;11:637247. doi: 10.3389/fonc.2021.637247. eCollection 2021.

BACKGROUND & AIMS: Cancer metastasis is responsible for the majority of cancer-related deaths. Exosomal miRNAs have emerged as promising biomarkers for cancer, serving as signaling molecules that can regulate tumor growth and metastasis. This study examined circulating exosomal miRNAs...

In Vitro and In Vivo Protective Effects of Lentil (.

Molecules (Basel, Switzerland)

Jung YS, Lee SH, Chun SY, Kim DH, Jang BI, Han MH, Lee SO.
PMID: 35011291
Molecules. 2021 Dec 23;27(1). doi: 10.3390/molecules27010059.

Excessive oxidative stress plays a role in hepatotoxicity and the pathogenesis of hepatic diseases. In our previous study, the phenolic extract of beluga lentil (BLE) showed the most potent in vitro antioxidant activity among extracts of four common varieties...

Fractional Chern insulators in magic-angle twisted bilayer graphene.

Nature

Xie Y, Pierce AT, Park JM, Parker DE, Khalaf E, Ledwith P, Cao Y, Lee SH, Chen S, Forrester PR, Watanabe K, Taniguchi T, Vishwanath A, Jarillo-Herrero P, Yacoby A.
PMID: 34912084
Nature. 2021 Dec;600(7889):439-443. doi: 10.1038/s41586-021-04002-3. Epub 2021 Dec 15.

Fractional Chern insulators (FCIs) are lattice analogues of fractional quantum Hall states that may provide a new avenue towards manipulating non-Abelian excitations. Early theoretical studies

Functional dissection of the phosphotransferase system provides insight into the prevalence of Faecalibacterium prausnitzii in the host intestinal environment.

Environmental microbiology

Kang D, Ham HI, Lee SH, Cho YJ, Kim YR, Yoon CK, Seok YJ.
PMID: 34296500
Environ Microbiol. 2021 Aug;23(8):4726-4740. doi: 10.1111/1462-2920.15681. Epub 2021 Jul 31.

Faecalibacterium prausnitzii is a dominant member of healthy human colon microbiota, regarded as a beneficial gut bacterium due to its ability to produce anti-inflammatory substances. However, little is known about how F. prausnitzii utilizes the nutrients present in the...

Impaired cerebro-cerebellar white matter connectivity and its associations with cognitive function in patients with schizophrenia.

NPJ schizophrenia

Kim SE, Jung S, Sung G, Bang M, Lee SH.
PMID: 34385473
NPJ Schizophr. 2021 Aug 12;7(1):38. doi: 10.1038/s41537-021-00169-w.

Schizophrenia is a complex brain disorder of unknown etiology. Based on the notion of "cognitive dysmetria," we aimed to investigate aberrations in structural white matter (WM) connectivity that links the cerebellum to cognitive dysfunction in patients with schizophrenia. A...

LGI1 governs neuritin-mediated resilience to chronic stress.

Neurobiology of stress

Lee SH, Kim NS, Choi M, Ko SY, Wang SE, Jo HR, Seo JY, Kim YS, Kim HJ, Lee HY, Kim JH, Son H.
PMID: 34401409
Neurobiol Stress. 2021 Jul 28;15:100373. doi: 10.1016/j.ynstr.2021.100373. eCollection 2021 Nov.

Depression is accompanied by neuronal atrophy and decreased neuroplasticity. Leucine-rich glioma-inactivated protein 1 (LGI1), a metastasis suppressor, plays an important role in the development of CNS synapses. We found that LGI1 expression was reduced in the hippocampi of mice...

Associations of variability in body weight and glucose levels with the risk of hip fracture in people with diabetes.

Metabolism: clinical and experimental

Lee J, Han K, Park SH, Kim MK, Lim DJ, Yoon KH, Kang MI, Lee SH.
PMID: 35032546
Metabolism. 2022 Jan 12;155135. doi: 10.1016/j.metabol.2022.155135. Epub 2022 Jan 12.

BACKGROUND: Diabetes is associated with a high risk of fragility fracture. However, there are controversies regarding the effect of fluctuations in metabolic parameters on the risk of fracture. We aimed to investigate the associations of body weight or glucose...

A Risk Prediction Model for Operative Mortality after Heart Valve Surgery in a Korean Cohort.

Journal of chest surgery

Kim HJ, Kim JB, Kim SO, Yun SC, Lee S, Lim C, Choi JW, Hwang HY, Kim KH, Lee SH, Yoo JS, Sung K, Je HG, Hong SC, Kim YJ, Kim SH, Chang BC.
PMID: 33790059
J Chest Surg. 2021 Apr 05;54(2):88-98. doi: 10.5090/jcs.20.102.

BACKGROUND: This study aimed to develop a new risk prediction model for operative mortality in a Korean cohort undergoing heart valve surgery using the Korea Heart Valve Surgery Registry (KHVSR) database.METHODS: We analyzed data from 4,742 patients registered in...

Response to blinatumomab or inotuzumab ozogamicin for isolated extramedullary relapse of adult acute lymphoblastic leukemia after allogeneic hematopoietic cell transplantation: a case study.

International journal of hematology

Lee SH, Yoon JH, Min GJ, Park SS, Park S, Lee SE, Cho BS, Eom KS, Kim YJ, Kim HJ, Min CK, Cho SG, Lee JW, Lee S.
PMID: 34617186
Int J Hematol. 2022 Jan;115(1):135-139. doi: 10.1007/s12185-021-03231-6. Epub 2021 Oct 06.

Isolated extramedullary relapse (EMR) without bone marrow relapse (BMR) after allogeneic hematopoietic cell transplantation (allo-HCT) is a rare condition in patients with acute lymphoblastic leukemia (ALL), and the role of immunotherapeutic agents for these patients remains unclear. We analyzed...

Showing 5881 to 5889 of 5889 entries