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Showing 3601 to 3611 of 3611 entries
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Chronic Lymphocytic Leukemia of the Aortic Valve: A Case Report.

Cureus

Posch ML, Prince SA, Thompson K, Modi F, Jordan J.
PMID: 33564521
Cureus. 2021 Jan 06;13(1):e12517. doi: 10.7759/cureus.12517.

Chronic lymphocytic leukemia (CLL) is characterized by the chronic accumulation of mature B-cell lymphocytes in the bone marrow. CLL accounts for approximately one-quarter of new leukemia cases each year and is the most common leukemia in Western countries. Most...

Sequence variation in the β7-β8 loop of bacterial class A sortase enzymes alters substrate selectivity.

The Journal of biological chemistry

Piper IM, Struyvenberg SA, Valgardson JD, Johnson DA, Gao M, Johnston K, Svendsen JE, Kodama HM, Hvorecny KL, Antos JM, Amacher JF.
PMID: 34302812
J Biol Chem. 2021 Aug;297(2):100981. doi: 10.1016/j.jbc.2021.100981. Epub 2021 Jul 22.

Gram-positive bacteria contain sortase enzymes on their cell surfaces that catalyze transpeptidation reactions critical for proper cellular function. In vitro, sortases are used in sortase-mediated ligation (SML) reactions for a variety of protein engineering applications. Historically, sortase A from...

Hematologic complications with age in Shwachman-Diamond syndrome.

Blood advances

Furutani E, Liu S, Galvin A, Steltz S, Malsch MM, Loveless SK, Mount L, Larson JH, Queenan K, Bertuch AA, Fleming MD, Gansner JM, Geddis AE, Hanna R, Keel SB, Lau BW, Lipton JM, Lorsbach R, Nakano TA, Vlachos A, Wang WC, Davies SM, Weller E, Myers KC, Shimamura A.
PMID: 34758064
Blood Adv. 2022 Jan 11;6(1):297-306. doi: 10.1182/bloodadvances.2021005539.

Shwachman-Diamond syndrome (SDS) is an inherited bone marrow failure syndrome with leukemia predisposition. An understanding of the hematologic complications of SDS with age could guide clinical management, but data are limited for this rare disease. We conducted a cohort...

Room for Improvement: The Trephination Procedure for Pediatric Patients with Pilonidal Disease.

The Journal of surgical research

Metzger GA, Apfeld JC, Nishimura L, Beyene TJ, Lutz C, Deans KJ, Minneci PC.
PMID: 34271267
J Surg Res. 2021 Nov;267:605-611. doi: 10.1016/j.jss.2021.06.010. Epub 2021 Jul 13.

BACKGROUND: Pilonidal disease is common amongst adolescent males and females and often leads to recurrent symptoms and life-altering morbidity. The traditional surgical approach includes wide excision of the involved area and carries a high rate of postoperative morbidity. A...

Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine.

Science advances

Wen J, Mercado GP, Volland A, Doden HL, Lickwar CR, Crooks T, Kakiyama G, Kelly C, Cocchiaro JL, Ridlon JM, Rawls JF.
PMID: 34301599
Sci Adv. 2021 Jul 23;7(30). doi: 10.1126/sciadv.abg1371. Print 2021 Jul.

Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all vertebrate classes. In mammals, bile salt composition is determined by host and microbial enzymes, affecting signaling through the bile salt-binding transcription factor farnesoid...

How university diversity rationales inform student preferences and outcomes.

Proceedings of the National Academy of Sciences of the United States of America

Starck JG, Sinclair S, Shelton JN.
PMID: 33846243
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2013833118.

It is currently commonplace for institutions of higher education to proclaim to embrace diversity and inclusion. Though there are numerous rationales available for doing so, US Supreme Court decisions have consistently favored rationales which assert that diversity provides compelling...

Correction: [On Becoming a Global Citizen: Transformative Learning Through Global Health Experiences].

Annals of global health

Litzelman DK, Gardner A, Einterz RM, Owiti P, Wambui C, Huskins JC, Schmitt-Wendholt KM, Stone GS, Ayuo PO, Inui TS, Cottingham AH, Umoren RA.
PMID: 33777711
Ann Glob Health. 2021 Mar 16;87(1):26. doi: 10.5334/aogh.3207.

[This corrects the article DOI: 10.1016/j.aogh.2017.07.005.].

Collaborative care for depression management in primary care: A randomized roll-out trial using a type 2 hybrid effectiveness-implementation design.

Contemporary clinical trials communications

Smith JD, Fu E, Rado J, Rosenthal LJ, Carroll AJ, Atlas JA, Carlo AD, Burnett-Zeigler I, Jordan N, Brown CH, Csernansky J.
PMID: 34401595
Contemp Clin Trials Commun. 2021 Jul 26;23:100823. doi: 10.1016/j.conctc.2021.100823. eCollection 2021 Sep.

BACKGROUND: The Collaborative Care Model (CoCM) is a well-established treatment for depression in primary care settings. The critical drivers and specific strategies for improving implementation and sustainment are largely unknown. Rigorous pragmatic research is needed to understand CoCM implementation...

Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals With Coronavirus Disease 2019.

Open forum infectious diseases

Regan J, Flynn JP, Rosenthal A, Jordan H, Li Y, Chishti R, Giguel F, Corry H, Coxen K, Fajnzylber J, Gillespie E, Kuritzkes DR, Hacohen N, Goldberg MB, Filbin MR, Yu XG, Baden L, Ribeiro RM, Perelson AS, Conway JM, Li JZ.
PMID: 34430669
Open Forum Infect Dis. 2021 Apr 17;8(8):ofab153. doi: 10.1093/ofid/ofab153. eCollection 2021 Aug.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms, whereas viremia peaked within 1 week of symptom-onset, suggesting early systemic...

ALVA: A Successful Program for Increasing the Number of Minority Undergraduates who Earn Engineering Degrees.

Peterson L, Pinkham S, Jordan C.
UIID-AD: 3081
2005;2005:447-454.

A highly successful minority outreach and support program for incoming college freshmen in engineering is described. The University of Washington has been running ALVA (Alliances for Learning and Vision for underrepresented Americans) for 11 years and continuously tracks its...

PROMISE: Maryland’s Alliance for Graduate Education and the Professoriate enhances recruitment and retention of underrepresented minority graduate students.

Carter FrancesD, Tull RenettaG, Rutledge JanetC, Warnick JordanE.
UIID-AD: 2228
2012;87:1562-1569. doi: 10.1097/ACM.0b013e31826d6796.

PROMISE: Maryland’s Alliance for Graduate Education and the Professoriate (AGEP), sponsored by the National Science Foundation, is a consortium that is designed to increase the numbers of underrepresented minority (URM) PhDs in science, technology, engineering, and mathematics fields who...

Showing 3601 to 3611 of 3611 entries