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Showing 9985 to 9996 of 24840 entries
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Artificial Neural Networks to Predict the Apparent Degree of Supersaturation in Supersaturated Lipid-Based Formulations: A Pilot Study.

Pharmaceutics

Bennett-Lenane H, O'Shea JP, Murray JD, Ilie AR, Holm R, Kuentz M, Griffin BT.
PMID: 34575483
Pharmaceutics. 2021 Sep 05;13(9). doi: 10.3390/pharmaceutics13091398.

In response to the increasing application of machine learning (ML) across many facets of pharmaceutical development, this pilot study investigated if ML, using artificial neural networks (ANNs), could predict the apparent degree of supersaturation (aDS) from two supersaturated LBFs...

Sticking to What Matters: A Matched Comparative Study of Fibrin Glue and Mechanical Fixation for Split-Thickness Skin Grafts in the Lower Extremity.

The international journal of lower extremity wounds

Othman S, Messa CA, Elfanagely O, Bormann B, Mellia JA, Broach RB, Kovach SJ, Fischer JP.
PMID: 34605281
Int J Low Extrem Wounds. 2021 Oct 04;15347346211047748. doi: 10.1177/15347346211047748. Epub 2021 Oct 04.

No abstract available.

Travel barriers, unemployment, and external fixation predict loss to follow-up after surgical management of lower extremity fractures in Dar es Salaam, Tanzania.

OTA international : the open access journal of orthopaedic trauma

Patterson JT, Albright PD, Jackson JH, Eliezer EN, Haonga BT, Morshed S, Shearer DW.
PMID: 33937685
OTA Int. 2020 Mar 03;3(1):e061. doi: 10.1097/OI9.0000000000000061. eCollection 2020 Mar.

OBJECTIVE: Predict loss to follow-up in prospective clinical investigations of lower extremity fracture surgery.DESIGN: Secondary analysis of 2 prospective clinical trials.SETTING: National public orthopaedic and neurologic trauma tertiary referral hospital in Dar es Salaam, Tanzania, a low-income country in...

Early application of topical antibiotic powder in open-fracture wounds: A strategy to prevent biofilm formation and infections.

OTA international : the open access journal of orthopaedic trauma

Burbank KM, Schauer SG, De Lorenzo RA, Wenke JC.
PMID: 33937714
OTA Int. 2020 Oct 12;3(4):e091. doi: 10.1097/OI9.0000000000000091. eCollection 2020 Dec.

Despite meticulous surgical care and systemic antibiotics, open fracture wounds have high rates of infection leading to increased morbidity. To reduce infection rates, orthopaedic surgeons may administer local antibiotics using various carriers that may be ineffective due to poor...

Shifted phase of EEG cross-frequency coupling in individuals with Phelan-McDermid syndrome.

Molecular autism

Mariscal MG, Berry-Kravis E, Buxbaum JD, Ethridge LE, Filip-Dhima R, Foss-Feig JH, Kolevzon A, Modi ME, Mosconi MW, Nelson CA, Powell CM, Siper PM, Soorya L, Thaliath A, Thurm A, Zhang B, Sahin M, Levin AR.
PMID: 33910615
Mol Autism. 2021 Apr 28;12(1):29. doi: 10.1186/s13229-020-00411-9.

BACKGROUND: Phelan-McDermid Syndrome (PMS) is a rare condition caused by deletion or mutation of the SHANK3 gene. Individuals with PMS frequently present with intellectual disability, autism spectrum disorder, and other neurodevelopmental challenges. Electroencephalography (EEG) can provide a window into...

Alexithymia disrupts emotion regulation processes and is associated with greater negative affect and alcohol problems.

Journal of clinical psychology

Linn BK, Zhao J, Bradizza CM, Lucke JF, Ruszczyk MU, Stasiewicz PR.
PMID: 34787929
J Clin Psychol. 2021 Dec;77(12):2915-2928. doi: 10.1002/jclp.23279. Epub 2021 Nov 17.

OBJECTIVE: Alexithymia is common among people who abuse alcohol, yet the mechanisms by which alexithymia exerts its influence remain unclear. This analysis tested a model whereby the three subscales of the Toronto Alexithymia Scale exert an indirect effect on...

Evidence of two-dimensional flat band at the surface of antiferromagnetic kagome metal FeSn.

Nature communications

Han M, Inoue H, Fang S, John C, Ye L, Chan MK, Graf D, Suzuki T, Ghimire MP, Cho WJ, Kaxiras E, Checkelsky JG.
PMID: 34526494
Nat Commun. 2021 Sep 15;12(1):5345. doi: 10.1038/s41467-021-25705-1.

The kagome lattice has long been regarded as a theoretical framework that connects lattice geometry to unusual singularities in electronic structure. Transition metal kagome compounds have been recently identified as a promising material platform to investigate the long-sought electronic...

Pityriasis Rosea: An Updated Review.

Current pediatric reviews

Leung AKC, Lam JM, Leong KF, Hon KL.
PMID: 32964824
Curr Pediatr Rev. 2021;17(3):201-211. doi: 10.2174/1573396316666200923161330.

BACKGROUND: Pityriasis rosea is a common acute, self-limited papulosquamous dermatosis that primarily affects children and young adults. The condition and its clinical variants may pose a diagnostic challenge, especially in the absence of the herald patch.OBJECTIVE: This article aimed...

Staurosporine Analogs Via C-H Borylation.

ACS medicinal chemistry letters

Gayler KM, Kong K, Reisenauer K, Taube JH, Wood JL.
PMID: 33335665
ACS Med Chem Lett. 2020 Oct 30;11(12):2441-2445. doi: 10.1021/acsmedchemlett.0c00420. eCollection 2020 Dec 10.

Staurosporine is among the most potent naturally occurring kinase inhibitors isolated to date and has served as a lead compound for numerous drug development efforts in several therapeutic areas. Herein we report that C-H borylation chemistry provides access to...

Erratum to "Changing the tone of clinical study design in the cannabis industry".

Translational neuroscience

Antony JM, McDonald AC, Noorbakhsh F, Guthrie N, Evans M.
PMID: 33335757
Transl Neurosci. 2020 Jun 03;11(1):192. doi: 10.1515/tnsci-2020-0110. eCollection 2020.

[This corrects the article on p. 4 in vol. 11, PMID: 32104589.].

Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks.

Nature

Keita AK, Koundouno FR, Faye M, Düx A, Hinzmann J, Diallo H, Ayouba A, Le Marcis F, Soropogui B, Ifono K, Diagne MM, Sow MS, Bore JA, Calvignac-Spencer S, Vidal N, Camara J, Keita MB, Renevey A, Diallo A, Soumah AK, Millimono SL, Mari-Saez A, Diop M, Doré A, Soumah FY, Kourouma K, Vielle NJ, Loucoubar C, Camara I, Kourouma K, Annibaldis G, Bah A, Thielebein A, Pahlmann M, Pullan ST, Carroll MW, Quick J, Formenty P, Legand A, Pietro K, Wiley MR, Tordo N, Peyrefitte C, McCrone JT, Rambaut A, Sidibé Y, Barry MD, Kourouma M, Saouromou CD, Condé M, Baldé M, Povogui M, Keita S, Diakite M, Bah MS, Sidibe A, Diakite D, Sako FB, Traore FA, Ki-Zerbo GA, Lemey P, Günther S, Kafetzopoulou LE, Sall AA, Delaporte E, Duraffour S, Faye O, Leendertz FH, Peeters M, Toure A, Magassouba NF.
PMID: 34526718
Nature. 2021 Sep;597(7877):539-543. doi: 10.1038/s41586-021-03901-9. Epub 2021 Sep 15.

Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the country faced a new outbreak-between 14 February and 19 June 2021-near the epicentre of the previous epidemic

A Prospective Study of Circulating Chemokines and Angiogenesis Markers and Risk of Multiple Myeloma and Its Precursor.

JNCI cancer spectrum

Hofmann JN, Landgren O, Landy R, Kemp TJ, Santo L, McShane CM, Shearer JJ, Lan Q, Rothman N, Pinto LA, Pfeiffer RM, Hildesheim A, Katki HA, Purdue MP.
PMID: 33336146
JNCI Cancer Spectr. 2019 Dec 16;4(2):pkz104. doi: 10.1093/jncics/pkz104. eCollection 2020 Apr.

BACKGROUND: Experimental and clinical studies have implicated certain chemokines and angiogenic cytokines in multiple myeloma (MM) pathogenesis. To investigate whether systemic concentrations of these markers are associated with future MM risk and progression from its precursor, monoclonal gammopathy of...

Showing 9985 to 9996 of 24840 entries