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Showing 13 to 24 of 28 entries
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Enzymatic/biochemical analysis of Actinomyces with commercial test kits with an emphasis on newly described species.

Anaerobe

Kerttula AM, Carlson P, Sarkonen N, Hall V, Könönen E.
PMID: 16701539
Anaerobe. 2005 Feb-Apr;11(1):99-108. doi: 10.1016/j.anaerobe.2004.11.002. Epub 2005 Feb 01.

In clinical microbiology laboratories, the identification of Actinomyces-like bacteria can be very laborious and problematic. In the present study, we focused on reactivity patterns of 4 commercial test kits, RapID ANA II, RapID 32A, RapID CB Plus, and BBL...

Denial of long-term issues with agriculture on tropical peatlands will have devastating consequences.

Global change biology

Wijedasa LS, Jauhiainen J, Könönen M, Lampela M, Vasander H, Leblanc MC, Evers S, Smith TE, Yule CM, Varkkey H, Lupascu M, Parish F, Singleton I, Clements GR, Aziz SA, Harrison ME, Cheyne S, Anshari GZ, Meijaard E, Goldstein JE, Waldron S, Hergoualc'h K, Dommain R, Frolking S, Evans CD, Posa MR, Glaser PH, Suryadiputra N, Lubis R, Santika T, Padfield R, Kurnianto S, Hadisiswoyo P, Lim TW, Page SE, Gauci V, Van Der Meer PJ, Buckland H, Garnier F, Samuel MK, Choo LN, O'Reilly P, Warren M, Suksuwan S, Sumarga E, Jain A, Laurance WF, Couwenberg J, Joosten H, Vernimmen R, Hooijer A, Malins C, Cochrane MA, Perumal B, Siegert F, Peh KS, Comeau LP, Verchot L, Harvey CF, Cobb A, Jaafar Z, Wösten H, Manuri S, Müller M, Giesen W, Phelps J, Yong DL, Silvius M, Wedeux BM, Hoyt A, Osaki M, Hirano T, Takahashi H, Kohyama TS, Haraguchi A, Nugroho NP, Coomes DA, Quoi LP, Dohong A, Gunawan H, Gaveau DL, Langner A, Lim FK, Edwards DP, Giam X, Van Der Werf G, Carmenta R, Verwer CC, Gibson L, Gandois L, Graham LL, Regalino J, Wich SA, Rieley J, Kettridge N, Brown C, Pirard R, Moore S, Capilla BR, Ballhorn U, Ho HC, Hoscilo A, Lohberger S, Evans TA, Yulianti N, Blackham G, Onrizal, Husson S, Murdiyarso D, Pangala S, Cole LE, Tacconi L, Segah H, Tonoto P, Lee JS, Schmilewski G, Wulffraat S, Putra EI, Cattau ME, Clymo RS, Morrison R, Mujahid A, Miettinen J, Liew SC, Valpola S, Wilson D, D'Arcy L, Gerding M, Sundari S, Thornton SA, Kalisz B, Chapman SJ, Su AS, Basuki I, Itoh M, Traeholt C, Sloan S, Sayok AK, Andersen R.
PMID: 27670948
Glob Chang Biol. 2017 Mar;23(3):977-982. doi: 10.1111/gcb.13516. Epub 2017 Jan 10.

No abstract available.

Salivary cytokine levels in early gingival inflammation.

Journal of oral microbiology

Belstrøm D, Damgaard C, Könönen E, Gürsoy M, Holmstrup P, Gürsoy UK.
PMID: 28839521
J Oral Microbiol. 2017 Aug 11;9(1):1364101. doi: 10.1080/20002297.2017.1364101. eCollection 2017.

Salivary protein levels have been studied in periodontitis. However, there is lack of information on salivary cytokine levels in early gingival inflammation. The aim of this study was to determine salivary levels of vascular endothelial growth factor (VEGF), interleukin...

Increased Inhibition in Non-Primary Motor Areas of String-Instrument Players: A Preliminary Study with Paired-Pulse Transcranial Magnetic Stimulation.

Brain plasticity (Amsterdam, Netherlands)

Vaalto S, Julkunen P, Säïsänen L, Könönen M, Määttä S, Karhu J.
PMID: 29765844
Brain Plast. 2016 Jun 29;1(2):223-234. doi: 10.3233/BPL-150015.

No abstract available.

Activation of Gingival Fibroblasts by Bacterial Cyclic Dinucleotides and Lipopolysaccharide.

Pathogens (Basel, Switzerland)

Elmanfi S, Sintim HO, Zhou J, Gürsoy M, Könönen E, Gürsoy UK.
PMID: 32993127
Pathogens. 2020 Sep 26;9(10). doi: 10.3390/pathogens9100792.

Human gingival fibroblasts (HGFs) recognize microbe-associated molecular patterns (MAMPs) and respond with inflammatory proteins. Simultaneous impacts of bacterial cyclic di-guanosine monophosphate (c-di-GMP), cyclic di-adenosine monophosphate (c-di-AMP), and lipopolysaccharide (LPS) on gingival keratinocytes have been previously demonstrated, but the effects...

Salivary Cytokine Biomarker Concentrations in Relation to Obesity and Periodontitis.

Journal of clinical medicine

Syrjäläinen S, Gursoy UK, Gursoy M, Pussinen P, Pietiäinen M, Jula A, Salomaa V, Jousilahti P, Könönen E.
PMID: 31817464
J Clin Med. 2019 Dec 05;8(12). doi: 10.3390/jcm8122152.

Systemic low-grade inflammation is associated with obesity. Our aim was to examine the association between obesity and salivary biomarkers of periodontitis. Salivary interleukin (IL)-1-receptor antagonist (IL-1Ra), IL-6, IL-8, IL-10, and tumor necrosis factor (TNF)-α concentrations were measured from 287...

Proton Radiation Hardness of Perovskite Tandem Photovoltaics.

Joule

Lang F, Jošt M, Frohna K, Köhnen E, Al-Ashouri A, Bowman AR, Bertram T, Morales-Vilches AB, Koushik D, Tennyson EM, Galkowski K, Landi G, Creatore M, Stannowski B, Kaufmann CA, Bundesmann J, Rappich J, Rech B, Denker A, Albrecht S, Neitzert HC, Nickel NH, Stranks SD.
PMID: 32467877
Joule. 2020 May 20;4(5):1054-1069. doi: 10.1016/j.joule.2020.03.006.

Monolithic [Cs

Immunological and Microbiological Profiling of Cumulative Risk Score for Periodontitis.

Diagnostics (Basel, Switzerland)

Liukkonen J, Gürsoy UK, Könönen E, Akhi R, Salminen A, Liljestrand JM, Pradhan-Palikhe P, Pietiäinen M, Sorsa T, Persson GR, Mäntylä P, Buhlin K, Paju S, Sinisalo J, Hörkkö S, Pussinen PJ.
PMID: 32764360
Diagnostics (Basel). 2020 Aug 05;10(8). doi: 10.3390/diagnostics10080560.

The cumulative risk score (CRS) is a mathematical salivary diagnostic model to define an individual's risk of having periodontitis. In order to further validate this salivary biomarker, we investigated how periodontal bacteria, lipopolysaccharide (LPS), and systemic and local host...

Salivary concentrations of macrophage activation-related chemokines are influenced by non-surgical periodontal treatment: a 12-week follow-up study.

Journal of oral microbiology

Grande MA, Belstrøm D, Damgaard C, Holmstrup P, Könönen E, Gursoy M, Gursoy UK.
PMID: 31893018
J Oral Microbiol. 2019 Dec 09;12(1):1694383. doi: 10.1080/20002297.2019.1694383. eCollection 2020.

No abstract available.

Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP.

Journal of oral microbiology

Onyedibe KI, Elmanfi S, Aryal UK, Könönen E, Gürsoy UK, Sintim HO.
PMID: 34992733
J Oral Microbiol. 2021 Dec 29;14(1):2003617. doi: 10.1080/20002297.2021.2003617. eCollection 2022.

BACKGROUND: Constant exposure of human gingival fibroblasts (HGFs) to oral pathogens trigger selective immune responses. Recently, the activation of immune response to cyclic dinucleotides (CDNs) via STING has come to the forefront. Reports show that other proteins outside the...

Anaerobes in the upper respiratory tract in infancy.

Anaerobe

Könönen E.
PMID: 16701543
Anaerobe. 2005 Jun;11(3):131-6. doi: 10.1016/j.anaerobe.2004.11.001. Epub 2005 Jan 26.

Development of the indigenous microbiota begins on the surfaces of the human body after birth when infants are exposed to continuous person-to-person and environmental contacts with microbes. Anaerobes constitute a significant part of indigenous bacterial communities at different body...

Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides.

Journal of oral microbiology

Elmanfi S, Zhou J, Sintim HO, Könönen E, Gürsoy M, Gürsoy UK.
PMID: 30598733
J Oral Microbiol. 2018 Nov 27;11(1):1538927. doi: 10.1080/20002297.2018.1538927. eCollection 2019.

BACKGROUND: Cyclic dinucleotides (cyclic di-guanosine monophosphate (c-di-GMP) and cyclic di-adenosine monophosphate (c-di-AMP)) and lipopolysaccharides (LPS) are pathogen-associated molecular patterns (PAMPs). Individual impacts of PAMPs on immune system have been evaluated, but simultaneous actions of multiple PAMPs have not been...

Showing 13 to 24 of 28 entries