Case reports in endocrinology

Oo YH, Karam JG, Resta CA.
PMID: 23424687
Case Rep Endocrinol. 2013;2013:520904. doi: 10.1155/2013/520904. Epub 2013 Jan 27.

Hyperglycemia is common in hospitalized patients and associated with adverse clinical outcomes. In hospitalized patients, multiple factors contribute to hyperglycemia, such as underlying medical conditions, pathophysiological stress, and medications. The development of transient insulin resistance is a known cause...

Diabetes, metabolic syndrome and obesity : targets and therapy

Karam J, McFarlane S.
PMID: 21437080
Diabetes Metab Syndr Obes. 2010 Apr 26;3:95-112.

The pandemic of overweight and obesity continues to rise in an alarming rate in western countries and around the globe representing a major public health challenge in desperate need for new strategies tackling obesity. In the United States nearly...

Journal of child & adolescent substance abuse

Dembo R, Briones-Robinson R, Barrett K, Ungaro R, Winters KC, Belenko S, Karas LM, Gulledge L, Wareham J.
PMID: 25400493
J Child Adolesc Subst Abuse. 2014;23(5):318-333. doi: 10.1080/1067828X.2014.928116.

Substance use and sexual risk behaviors are common among adolescents. Although attention has focused primarily on alcohol use, less is known about the relationship between marijuana use and sexual risk behavior among high-risk youth. Since truant youth often experience...

European heart journal. Cardiovascular Imaging

Jellis CL, Park MM, Abidov A, Borlaug BA, Brittain EL, Frantz R, Hassoun PM, Horn EM, Jaber WA, Jiwon K, Karas MG, Kwon D, Leopold JA, Maron B, Mathai SC, Mehra R, Rischard F, Rosenzweig EB, Tang WHW, Vanderpool R, Thomas JD.
PMID: 34097027
Eur Heart J Cardiovasc Imaging. 2021 Jun 07; doi: 10.1093/ehjci/jeab065. Epub 2021 Jun 07.

AIMS: There is a wide spectrum of diseases associated with pulmonary hypertension, pulmonary vascular remodelling, and right ventricular dysfunction. The NIH-sponsored PVDOMICS network seeks to perform comprehensive clinical phenotyping and endophenotyping across these disorders to further evaluate and define...

Journal of the American Chemical Society

Karas LJ, Wu CH, Wu JI.
PMID: 34672631
J Am Chem Soc. 2021 Nov 03;143(43):17970-17974. doi: 10.1021/jacs.1c09324. Epub 2021 Oct 21.

Many popular organic chromophores that catalyze photoinduced proton-coupled electron transfer (PCET) reactions are aromatic in the ground state but become excited-state antiaromatic in the lowest ππ* state. We show that excited-state antiaromaticity makes electron transfer easier. Two representative photoinduced...

Chemical science

Karas LJ, Wu CH, Ottosson H, Wu JI.
PMID: 34094268
Chem Sci. 2020 Aug 12;11(37):10071-10077. doi: 10.1039/d0sc02294b.

The Watson-Crick A·T and G·C base pairs are not only electronically complementary, but also photochemically complementary. Upon UV irradiation, DNA base pairs undergo efficient excited-state deactivation through electron driven proton transfer (EDPT), also known as proton-coupled electron transfer (PCET),...

PeerJ

Schindler BY, Vasl A, Blaustein L, Gurevich D, Kadas GJ, Seifan M.
PMID: 30918748
PeerJ. 2019 Mar 19;7:e6445. doi: 10.7717/peerj.6445. eCollection 2019.

Green roofs, which are roofs with growing substrate and vegetation, can provide habitat for arthropods in cities. Maintaining a diversity of arthropods in an urban environment can enhance the functions they fill, such as pest control and soil development....

Plant physiology

Karas BJ, Ross L, Novero M, Amyot L, Shrestha A, Inada S, Nakano M, Sakai T, Bonetta D, Sato S, Murray JD, Bonfante P, Szczyglowski K.
PMID: 34618101
Plant Physiol. 2021 Aug 03;186(4):2037-2050. doi: 10.1093/plphys/kiab204.

Root hair cells form the primary interface of plants with the soil environment, playing key roles in nutrient uptake and plant defense. In legumes, they are typically the first cells to become infected by nitrogen-fixing soil bacteria during root...

mSystems

Hussein M, Karas JA, Schneider-Futschik EK, Chen F, Swarbrick J, Paulin OKA, Hoyer D, Baker M, Zhu Y, Li J, Velkov T.
PMID: 32457238
mSystems. 2020 May 26;5(3). doi: 10.1128/mSystems.00077-20.

Antibiotics have served humankind through their use in modern medicine as effective treatments for otherwise fatal bacterial infections. Teixobactin is a first member of newly discovered natural antibiotics that was recently identified from a hitherto-unculturable soil bacterium,

Bio-protocol

Wang H, Slattery SS, Karas BJ, Edgell DR.
PMID: 34395776
Bio Protoc. 2018 Aug 20;8(16):e2974. doi: 10.21769/BioProtoc.2974. eCollection 2018 Aug 20.

Diatoms are an ecologically important group of eukaryotic microalgae with properties that make them attractive for biotechnological applications such as biofuels, foods, cosmetics and pharmaceuticals.

European journal of heart failure

Lu DY, Adelsheimer A, Chan K, Yeo I, Krishnan U, Karas MG, Horn EM, Feldman DN, Sobol I, Goyal P, Bhatt R, Batra S, Sciria CT, Olonoff D, Cheung JW, Kim LK.
PMID: 34114302
Eur J Heart Fail. 2021 Nov;23(11):1927-1937. doi: 10.1002/ejhf.2263. Epub 2021 Jun 22.

AIMS: Cardiogenic shock (CS) is associated with significant mortality, and there is a movement towards regional 'hub-and-spoke' triage systems to coordinate care and resources. Limited data exist on outcomes of patients treated at CS transfer hubs.METHODS AND RESULTS: Cardiogenic...

Drug and alcohol dependence

Degenhardt L, Bharat C, Chiu WT, Harris MG, Kazdin AE, Vigo DV, Sampson NA, Alonso J, Andrade LH, Bruffaerts R, Bunting B, Cardoso G, de Girolamo G, Florescu S, Gureje O, Haro JM, Hu C, Karam AN, Karam EG, Kovess-Masfety V, Lee S, Makanjuola V, McGrath JJ, Medina-Mora ME, Moskalewicz J, Navarro-Mateu F, Posada-Villa J, Rapsey C, Stagnaro JC, Tachimori H, Ten Have M, Torres Y, Williams DR, Zarkov Z, Kessler RC.
PMID: 34784556
Drug Alcohol Depend. 2021 Dec 01;229:109158. doi: 10.1016/j.drugalcdep.2021.109158. Epub 2021 Nov 01.

AIM: We examined prevalence and factors associated with receiving perceived helpful alcohol use disorder (AUD) treatment, and persistence in help-seeking after earlier unhelpful treatment.METHODS: Data came from 27 community epidemiologic surveys of adults in 24 countries using the World...