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Showing 49 to 52 of 52 entries
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Ethics of DNA research on human remains: five globally applicable guidelines.

Nature

Alpaslan-Roodenberg S, Anthony D, Babiker H, Bánffy E, Booth T, Capone P, Deshpande-Mukherjee A, Eisenmann S, Fehren-Schmitz L, Frachetti M, Fujita R, Frieman CJ, Fu Q, Gibbon V, Haak W, Hajdinjak M, Hofmann KP, Holguin B, Inomata T, Kanzawa-Kiriyama H, Keegan W, Kelso J, Krause J, Kumaresan G, Kusimba C, Kusimba S, Lalueza-Fox C, Llamas B, MacEachern S, Mallick S, Matsumura H, Morales-Arce AY, Matuzeviciute GM, Mushrif-Tripathy V, Nakatsuka N, Nores R, Ogola C, Okumura M, Patterson N, Pinhasi R, Prasad SPR, Prendergast ME, Punzo JL, Reich D, Sawafuji R, Sawchuk E, Schiffels S, Sedig J, Shnaider S, Sirak K, Skoglund P, Slon V, Snow M, Soressi M, Spriggs M, Stockhammer PW, Szécsényi-Nagy A, Thangaraj K, Tiesler V, Tobler R, Wang CC, Warinner C, Yasawardene S, Zahir M.
PMID: 34671160
Nature. 2021 Nov;599(7883):41-46. doi: 10.1038/s41586-021-04008-x. Epub 2021 Oct 20.

We are a group of archaeologists, anthropologists, curators and geneticists representing diverse global communities and 31 countries. All of us met in a virtual workshop dedicated to ethics in ancient DNA research held in November 2020. There was widespread...

The effect of tracer contact on return to care among adult, "lost to follow-up" patients living with HIV in Zambia: an instrumental variable analysis.

Journal of the International AIDS Society

Beres LK, Mody A, Sikombe K, Nicholas LH, Schwartz S, Eshun-Wilson I, Somwe P, Simbeza S, Pry JM, Kaumba P, McGready J, Holmes CB, Bolton-Moore C, Sikazwe I, Denison JA, Geng EH.
PMID: 34921515
J Int AIDS Soc. 2021 Dec;24(12):e25853. doi: 10.1002/jia2.25853.

INTRODUCTION: Tracing patients lost to follow-up (LTFU) from HIV care is widely practiced, yet we have little knowledge of its causal effect on care engagement. In a prospective, Zambian cohort, we examined the effect of tracing on return to...

Microscale thermophoresis analysis of the molecular interaction between small nuclear ribonucleoprotein polypeptide G and the RING finger domain of RBBP6 towards anti-cancer drug discovery.

American journal of translational research

Mabonga L, Masamba P, Basson AK, Kappo AP.
PMID: 34956492
Am J Transl Res. 2021 Nov 15;13(11):12775-12785. eCollection 2021.

Regulatory core-splicing proteins are now becoming highly promising therapeutic targets for the development of anti-cancer drugs. SNRPG and RBBP6 are two good examples of regulatory core-splicing proteins involved in tumorigenesis and tumor development whose multi-functional role is primarily mediated...

Proteins as Targets in Anti-Schistosomal Drug Discovery and Vaccine Development.

Vaccines

Qokoyi NK, Masamba P, Kappo AP.
PMID: 34358178
Vaccines (Basel). 2021 Jul 08;9(7). doi: 10.3390/vaccines9070762.

Proteins hardly function in isolation; they form complexes with other proteins or molecules to mediate cell signaling and control cellular processes in various organisms. Protein interactions control mechanisms that lead to normal and/or disease states. The use of competitive...

Showing 49 to 52 of 52 entries