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Showing 13 to 24 of 85 entries
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Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes.

Organic & biomolecular chemistry

Chada RR, Kajare RC, Bhandari MC, Mohammed SZ, Khatravath M, Warudikar K, Punna N.
PMID: 33403372
Org Biomol Chem. 2021 Jan 28;19(4):809-821. doi: 10.1039/d0ob02279a. Epub 2021 Jan 06.

An efficient approach for the highly diastereoselective construction of functionalized cyclopenta[d][1,2]oxazines via sequential oxyamination and Pauson-Khand reaction of readily accessible propargylic alcohols has been developed. Furthermore, the ring closing metathesis of these N-O linked 1,7-enynes afforded vinylated-[1,2]oxazines in good...

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Chada RR, Kajare RC, Bhandari MC, et al. Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes. Org Biomol Chem. 2021;19(4):809-821doi: 10.1039/d0ob02279a.
Chada, R. R., Kajare, R. C., Bhandari, M. C., Mohammed, S. Z., Khatravath, M., Warudikar, K., & Punna, N. (2021). Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes. Organic & biomolecular chemistry, 19(4), 809-821. https://doi.org/10.1039/d0ob02279a
Chada, Raji Reddy, et al. "Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes." Organic & biomolecular chemistry vol. 19,4 (2021): 809-821. doi: https://doi.org/10.1039/d0ob02279a
Chada RR, Kajare RC, Bhandari MC, Mohammed SZ, Khatravath M, Warudikar K, Punna N. Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes. Org Biomol Chem. 2021 Jan 28;19(4):809-821. doi: 10.1039/d0ob02279a. Epub 2021 Jan 06. PMID: 33403372.
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Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema.

Biology

Mehrara BJ, Park HJ, Kataru RP, Bromberg J, Coriddi M, Baik JE, Shin J, Li C, Cavalli MR, Encarnacion EM, Lee M, Van Zee KJ, Riedel E, Dayan JH.
PMID: 34571811
Biology (Basel). 2021 Sep 18;10(9). doi: 10.3390/biology10090934.

Recent studies suggest that Th2 cells play a key role in the pathology of secondary lymphedema by elaborating cytokines such as IL4 and IL13. The aim of this study was to test the efficacy of QBX258, a monoclonal IL4/IL13...

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Mehrara BJ, Park HJ, Kataru RP, et al. Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema. Biology (Basel). 2021;10(9)doi: 10.3390/biology10090934.
Mehrara, B. J., Park, H. J., Kataru, R. P., Bromberg, J., Coriddi, M., Baik, J. E., Shin, J., Li, C., Cavalli, M. R., Encarnacion, E. M., Lee, M., Van Zee, K. J., Riedel, E., & Dayan, J. H. (2021). Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema. Biology, 10(9), . https://doi.org/10.3390/biology10090934
Mehrara, Babak J, et al. "Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema." Biology vol. 10,9 (2021). doi: https://doi.org/10.3390/biology10090934
Mehrara BJ, Park HJ, Kataru RP, Bromberg J, Coriddi M, Baik JE, Shin J, Li C, Cavalli MR, Encarnacion EM, Lee M, Van Zee KJ, Riedel E, Dayan JH. Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema. Biology (Basel). 2021 Sep 18;10(9). doi: 10.3390/biology10090934. PMID: 34571811; PMCID: PMC8466465.
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The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells.

Current research in pharmacology and drug discovery

Mengeste AM, Lund J, Katare P, Ghobadi R, Bakke HG, Lunde PK, Eide L, Mahony GO, Göpel S, Peng XR, Kase ET, Thoresen GH, Rustan AC.
PMID: 34909682
Curr Res Pharmacol Drug Discov. 2021 Sep 28;2:100060. doi: 10.1016/j.crphar.2021.100060. eCollection 2021.

BACKGROUND AND OBJECTIVE: A number of studies have highlighted muscle-specific mechanisms of thermogenesis involving futile cycling of CaMETHODS: In this study, we used primary myotube cultures derived from muscle biopsies of the RESULTS: Both acute (4 ​h) and chronic...

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Mengeste AM, Lund J, Katare P, et al. The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells. Curr Res Pharmacol Drug Discov. 2021;2:100060doi: 10.1016/j.crphar.2021.100060.
Mengeste, A. M., Lund, J., Katare, P., Ghobadi, R., Bakke, H. G., Lunde, P. K., Eide, L., Mahony, G. O., Göpel, S., Peng, X. R., Kase, E. T., Thoresen, G. H., & Rustan, A. C. (2021). The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells. Current research in pharmacology and drug discovery, 2100060. https://doi.org/10.1016/j.crphar.2021.100060
Mengeste, Abel M, et al. "The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells." Current research in pharmacology and drug discovery vol. 2 (2021): 100060. doi: https://doi.org/10.1016/j.crphar.2021.100060
Mengeste AM, Lund J, Katare P, Ghobadi R, Bakke HG, Lunde PK, Eide L, Mahony GO, Göpel S, Peng XR, Kase ET, Thoresen GH, Rustan AC. The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells. Curr Res Pharmacol Drug Discov. 2021 Sep 28;2:100060. doi: 10.1016/j.crphar.2021.100060. eCollection 2021. PMID: 34909682; PMCID: PMC8663964.
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Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function.

Science signaling

Kataru RP, Baik JE, Park HJ, Ly CL, Shin J, Schwartz N, Lu TT, Ortega S, Mehrara BJ.
PMID: 34376570
Sci Signal. 2021 Aug 10;14(695). doi: 10.1126/scisignal.abc0836.

Exogenous administration of lymphangiogenic growth factors is widely used to study changes in lymphatic function in pathophysiology. However, this approach can result in off-target effects, thereby generating conflicting data. To circumvent this issue, we modulated intracellular VEGF-C signaling by...

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Kataru RP, Baik JE, Park HJ, et al. Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Sci Signal. 2021;14(695)doi: 10.1126/scisignal.abc0836.
Kataru, R. P., Baik, J. E., Park, H. J., Ly, C. L., Shin, J., Schwartz, N., Lu, T. T., Ortega, S., & Mehrara, B. J. (2021). Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Science signaling, 14(695), . https://doi.org/10.1126/scisignal.abc0836
Kataru, Raghu P, et al. "Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function." Science signaling vol. 14,695 (2021). doi: https://doi.org/10.1126/scisignal.abc0836
Kataru RP, Baik JE, Park HJ, Ly CL, Shin J, Schwartz N, Lu TT, Ortega S, Mehrara BJ. Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Sci Signal. 2021 Aug 10;14(695). doi: 10.1126/scisignal.abc0836. PMID: 34376570; PMCID: PMC8567054.
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Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox.

Comparative hepatology

Higashi N, Imai K, Sato M, Sato T, Kojima N, Miura M, Wold HL, Moskaug J , Berg T, Norum KR, Roos N, Wake K, Blomhoff R, Senoo H.
PMID: 14960168
Comp Hepatol. 2004 Jan 14;3:S16. doi: 10.1186/1476-5926-2-S1-S16.

We examined the liver of adult polar bears, arctic foxes, and rats by gold chloride staining, fluorescence microscopy for the detection of autofluorescence of vitamin A, hematoxylin-eosin staining, staining with Masson's trichrome, Ishii and Ishii's silver impregnation, and transmission...

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Higashi N, Imai K, Sato M, et al. Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox. Comp Hepatol. 2004;3:S16doi: 10.1186/1476-5926-2-S1-S16.
Higashi, N., Imai, K., Sato, M., Sato, T., Kojima, N., Miura, M., Wold, H. L., Moskaug J , Berg, T., Norum, K. R., Roos, N., Wake, K., Blomhoff, R., & Senoo, H. (2004). Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox. Comparative hepatology, 3S16. https://doi.org/10.1186/1476-5926-2-S1-S16
Higashi, Nobuyo, et al. "Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox." Comparative hepatology vol. 3 (2004): S16. doi: https://doi.org/10.1186/1476-5926-2-S1-S16
Higashi N, Imai K, Sato M, Sato T, Kojima N, Miura M, Wold HL, Moskaug J , Berg T, Norum KR, Roos N, Wake K, Blomhoff R, Senoo H. Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox. Comp Hepatol. 2004 Jan 14;3:S16. doi: 10.1186/1476-5926-2-S1-S16. PMID: 14960168; PMCID: PMC2409438.
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Efficacy of Atorvastatin in Prevention of Contrast-induced Nephropathy in High-risk Patients Undergoing Angiography: A Double-blind Randomized Controlled Trial.

Journal of pharmacology & pharmacotherapeutics

Syed MH, Khandelwal PN, Thawani VR, Katare SS.
PMID: 28706398
J Pharmacol Pharmacother. 2017 Apr-Jun;8(2):50-53. doi: 10.4103/jpp.JPP_156_16.

OBJECTIVE: To evaluate the efficacy and safety of atorvastatin (ATN) 80 mg in the prevention of contrast medium- induced nephropathy (CIN) in high risk patients undergoing angiograph.MATERIALS AND METHODS: This was a prospective, double-blind, two-arm, parallel group RCT. A...

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Syed MH, Khandelwal PN, Thawani VR, et al. Efficacy of Atorvastatin in Prevention of Contrast-induced Nephropathy in High-risk Patients Undergoing Angiography: A Double-blind Randomized Controlled Trial. J Pharmacol Pharmacother. 2017;8(2):50-53doi: 10.4103/jpp.JPP_156_16.
Syed, M. H., Khandelwal, P. N., Thawani, V. R., & Katare, S. S. (2017). Efficacy of Atorvastatin in Prevention of Contrast-induced Nephropathy in High-risk Patients Undergoing Angiography: A Double-blind Randomized Controlled Trial. Journal of pharmacology & pharmacotherapeutics, 8(2), 50-53. https://doi.org/10.4103/jpp.JPP_156_16
Syed, Maaz Hussain, et al. "Efficacy of Atorvastatin in Prevention of Contrast-induced Nephropathy in High-risk Patients Undergoing Angiography: A Double-blind Randomized Controlled Trial." Journal of pharmacology & pharmacotherapeutics vol. 8,2 (2017): 50-53. doi: https://doi.org/10.4103/jpp.JPP_156_16
Syed MH, Khandelwal PN, Thawani VR, Katare SS. Efficacy of Atorvastatin in Prevention of Contrast-induced Nephropathy in High-risk Patients Undergoing Angiography: A Double-blind Randomized Controlled Trial. J Pharmacol Pharmacother. 2017 Apr-Jun;8(2):50-53. doi: 10.4103/jpp.JPP_156_16. PMID: 28706398; PMCID: PMC5497399.
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Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option.

Frontiers in endocrinology

Neale JPH, Pearson JT, Katare R, Schwenke DO.
PMID: 29326658
Front Endocrinol (Lausanne). 2017 Dec 13;8:350. doi: 10.3389/fendo.2017.00350. eCollection 2017.

Critical limb ischemia (CLI) is the most severe manifestation of peripheral artery disease. It is characterized by chronic pain at rest, skin ulcerations, and gangrene tissue loss. CLI is a highly morbid condition, resulting in a severely diminished quality...

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Neale JPH, Pearson JT, Katare R, et al. Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option. Front Endocrinol (Lausanne). 2017;8:350doi: 10.3389/fendo.2017.00350.
Neale, J. P. H., Pearson, J. T., Katare, R., & Schwenke, D. O. (2017). Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option. Frontiers in endocrinology, 8350. https://doi.org/10.3389/fendo.2017.00350
Neale, Joshua P H, et al. "Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option." Frontiers in endocrinology vol. 8 (2017): 350. doi: https://doi.org/10.3389/fendo.2017.00350
Neale JPH, Pearson JT, Katare R, Schwenke DO. Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option. Front Endocrinol (Lausanne). 2017 Dec 13;8:350. doi: 10.3389/fendo.2017.00350. eCollection 2017. PMID: 29326658; PMCID: PMC5733488.
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Sigma-2 receptor ligand anchored telmisartan loaded nanostructured lipid particles augmented drug delivery, cytotoxicity, apoptosis and cellular uptake in prostate cancer cells.

Drug development and industrial pharmacy

Puri R, Kaur Bhatia R, Shankar Pandey R, Kumar Jain U, Katare OP, Madan J.
PMID: 27184705
Drug Dev Ind Pharm. 2016 Dec;42(12):2020-2030. doi: 10.1080/03639045.2016.1190741. Epub 2016 Jun 01.

Recently, the anticancer activity of telmisartan (TEL) has been discovered against prostate cancer. Nevertheless, despite favorable therapeutic profile, poor aqueous solubility and suboptimal oral bioavailability hamper the anticancer efficacy of TEL. Therefore, in this investigation, sigma-2 receptor ligand, 3-(4-cyclohexylpiperazine-1-yl)...

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Puri R, Kaur Bhatia R, Shankar Pandey R, et al. Sigma-2 receptor ligand anchored telmisartan loaded nanostructured lipid particles augmented drug delivery, cytotoxicity, apoptosis and cellular uptake in prostate cancer cells. Drug Dev Ind Pharm. 2016;42(12):2020-2030doi: 10.1080/03639045.2016.1190741.
Puri, R., Kaur Bhatia, R., Shankar Pandey, R., Kumar Jain, U., Katare, O. P., & Madan, J. (2016). Sigma-2 receptor ligand anchored telmisartan loaded nanostructured lipid particles augmented drug delivery, cytotoxicity, apoptosis and cellular uptake in prostate cancer cells. Drug development and industrial pharmacy, 42(12), 2020-2030. https://doi.org/10.1080/03639045.2016.1190741
Puri, Richa, et al. "Sigma-2 receptor ligand anchored telmisartan loaded nanostructured lipid particles augmented drug delivery, cytotoxicity, apoptosis and cellular uptake in prostate cancer cells." Drug development and industrial pharmacy vol. 42,12 (2016): 2020-2030. doi: https://doi.org/10.1080/03639045.2016.1190741
Puri R, Kaur Bhatia R, Shankar Pandey R, Kumar Jain U, Katare OP, Madan J. Sigma-2 receptor ligand anchored telmisartan loaded nanostructured lipid particles augmented drug delivery, cytotoxicity, apoptosis and cellular uptake in prostate cancer cells. Drug Dev Ind Pharm. 2016 Dec;42(12):2020-2030. doi: 10.1080/03639045.2016.1190741. Epub 2016 Jun 01. PMID: 27184705.
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A Review on Hepatoprotective and Immunomodulatory Herbal Plants.

Pharmacognosy reviews

Ilyas U, Katare DP, Aeri V, Naseef PP.
PMID: 27041876
Pharmacogn Rev. 2016 Jan-Jun;10(19):66-70. doi: 10.4103/0973-7847.176544.

The liver is the most important organ that plays an important role in maintaining various physiological processes in the body. Hepatitis is an inflammation of the liver and is characterized by the presence of inflammatory cells in the tissue...

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Ilyas U, Katare DP, Aeri V, et al. A Review on Hepatoprotective and Immunomodulatory Herbal Plants. Pharmacogn Rev. 2016;10(19):66-70doi: 10.4103/0973-7847.176544.
Ilyas, U., Katare, D. P., Aeri, V., & Naseef, P. P. (2016). A Review on Hepatoprotective and Immunomodulatory Herbal Plants. Pharmacognosy reviews, 10(19), 66-70. https://doi.org/10.4103/0973-7847.176544
Ilyas, Uorakkottil, et al. "A Review on Hepatoprotective and Immunomodulatory Herbal Plants." Pharmacognosy reviews vol. 10,19 (2016): 66-70. doi: https://doi.org/10.4103/0973-7847.176544
Ilyas U, Katare DP, Aeri V, Naseef PP. A Review on Hepatoprotective and Immunomodulatory Herbal Plants. Pharmacogn Rev. 2016 Jan-Jun;10(19):66-70. doi: 10.4103/0973-7847.176544. PMID: 27041876; PMCID: PMC4791991.
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Emphysematous cholecystitis: Imaging findings in nine patients.

The Indian journal of radiology & imaging

Sunnapwar A, Raut AA, Nagar AM, Katre R.
PMID: 21799598
Indian J Radiol Imaging. 2011 Apr;21(2):142-6. doi: 10.4103/0971-3026.82300.

OBJECTIVE: Emphysematous cholecystitis is a severe form of acute cholecystitis and can be rapidly fatal. We present the imaging features of nine patients with proven emphysematous cholecystitis.

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Sunnapwar A, Raut AA, Nagar AM, et al. Emphysematous cholecystitis: Imaging findings in nine patients. Indian J Radiol Imaging. 2011;21(2):142-6doi: 10.4103/0971-3026.82300.
Sunnapwar, A., Raut, A. A., Nagar, A. M., & Katre, R. (2011). Emphysematous cholecystitis: Imaging findings in nine patients. The Indian journal of radiology & imaging, 21(2), 142-6. https://doi.org/10.4103/0971-3026.82300
Sunnapwar, Abhijit, et al. "Emphysematous cholecystitis: Imaging findings in nine patients." The Indian journal of radiology & imaging vol. 21,2 (2011): 142-6. doi: https://doi.org/10.4103/0971-3026.82300
Sunnapwar A, Raut AA, Nagar AM, Katre R. Emphysematous cholecystitis: Imaging findings in nine patients. Indian J Radiol Imaging. 2011 Apr;21(2):142-6. doi: 10.4103/0971-3026.82300. PMID: 21799598; PMCID: PMC3137852.
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Making polymeric micro- and nanoparticles of complex shapes.

Proceedings of the National Academy of Sciences of the United States of America

Champion JA, Katare YK, Mitragotri S.
PMID: 17620615
Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):11901-4. doi: 10.1073/pnas.0705326104. Epub 2007 Jul 09.

Polymeric micro- and nanoparticles play a central role in varied applications such as drug delivery, medical imaging, and advanced materials, as well as in fundamental studies in fields such as microfluidics and nanotechnology. Functional behavior of polymeric particles in...

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Champion JA, Katare YK, Mitragotri S. Making polymeric micro- and nanoparticles of complex shapes. Proc Natl Acad Sci U S A. 2007;104(29):11901-4doi: 10.1073/pnas.0705326104.
Champion, J. A., Katare, Y. K., & Mitragotri, S. (2007). Making polymeric micro- and nanoparticles of complex shapes. Proceedings of the National Academy of Sciences of the United States of America, 104(29), 11901-4. https://doi.org/10.1073/pnas.0705326104
Champion, Julie A, et al. "Making polymeric micro- and nanoparticles of complex shapes." Proceedings of the National Academy of Sciences of the United States of America vol. 104,29 (2007): 11901-4. doi: https://doi.org/10.1073/pnas.0705326104
Champion JA, Katare YK, Mitragotri S. Making polymeric micro- and nanoparticles of complex shapes. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):11901-4. doi: 10.1073/pnas.0705326104. Epub 2007 Jul 09. PMID: 17620615; PMCID: PMC1924596.
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Extracellular Matrix Scaffold Technology for Bioartificial Pancreas Engineering: State of the Art and Future Challenges.

Journal of diabetes science and technology

Salvatori M, Katari R, Patel T, Peloso A, Mugweru J, Owusu K, Orlando G, Varghese N.
PMID: 24876552
J Diabetes Sci Technol. 2014 Jan;8(1):159-169. doi: 10.1177/1932296813519558. Epub 2014 Jan 01.

Emergent technologies in regenerative medicine may soon overcome the limitations of conventional diabetes therapies. Collaborative efforts across the subfields of stem cell technology, islet encapsulation, and biomaterial carriers seek to produce a bioengineered pancreas capable of restoring endocrine function...

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Salvatori M, Katari R, Patel T, et al. Extracellular Matrix Scaffold Technology for Bioartificial Pancreas Engineering: State of the Art and Future Challenges. J Diabetes Sci Technol. 2014;8(1):159-169doi: 10.1177/1932296813519558.
Salvatori, M., Katari, R., Patel, T., Peloso, A., Mugweru, J., Owusu, K., Orlando, G., & Varghese, N. (2014). Extracellular Matrix Scaffold Technology for Bioartificial Pancreas Engineering: State of the Art and Future Challenges. Journal of diabetes science and technology, 8(1), 159-169. https://doi.org/10.1177/1932296813519558
Salvatori, Marcus, et al. "Extracellular Matrix Scaffold Technology for Bioartificial Pancreas Engineering: State of the Art and Future Challenges." Journal of diabetes science and technology vol. 8,1 (2014): 159-169. doi: https://doi.org/10.1177/1932296813519558
Salvatori M, Katari R, Patel T, Peloso A, Mugweru J, Owusu K, Orlando G, Varghese N. Extracellular Matrix Scaffold Technology for Bioartificial Pancreas Engineering: State of the Art and Future Challenges. J Diabetes Sci Technol. 2014 Jan;8(1):159-169. doi: 10.1177/1932296813519558. Epub 2014 Jan 01. PMID: 24876552; PMCID: PMC4454093.
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