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PAT implementation for advanced process control in solid dosage manufacturing - A practical guide.

International journal of pharmaceutics

Sacher S, Poms J, Rehrl J, Khinast JG.
PMID: 34952147
Int J Pharm. 2021 Dec 21;613:121408. doi: 10.1016/j.ijpharm.2021.121408. Epub 2021 Dec 21.

The implementation of continuous pharmaceutical manufacturing requires advanced control strategies rather than traditional end product testing or an operation within a small range of controlled parameters. A high level of automation based on process models and hierarchical control concepts...

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Sacher S, Poms J, Rehrl J, et al. PAT implementation for advanced process control in solid dosage manufacturing - A practical guide. Int J Pharm. 2021;613:121408doi: 10.1016/j.ijpharm.2021.121408.
Sacher, S., Poms, J., Rehrl, J., & Khinast, J. G. (2021). PAT implementation for advanced process control in solid dosage manufacturing - A practical guide. International journal of pharmaceutics, 613121408. https://doi.org/10.1016/j.ijpharm.2021.121408
Sacher, Stephan, et al. "PAT implementation for advanced process control in solid dosage manufacturing - A practical guide." International journal of pharmaceutics vol. 613 (2021): 121408. doi: https://doi.org/10.1016/j.ijpharm.2021.121408
Sacher S, Poms J, Rehrl J, Khinast JG. PAT implementation for advanced process control in solid dosage manufacturing - A practical guide. Int J Pharm. 2021 Dec 21;613:121408. doi: 10.1016/j.ijpharm.2021.121408. Epub 2021 Dec 21. PMID: 34952147.
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PAT implementation for advanced process control in solid dosage manufacturing - A practical guide.

International journal of pharmaceutics

Sacher S, Poms J, Rehrl J, Khinast JG.
PMID: 34952147
Int J Pharm. 2021 Dec 21;613:121408. doi: 10.1016/j.ijpharm.2021.121408. Epub 2021 Dec 21.

The implementation of continuous pharmaceutical manufacturing requires advanced control strategies rather than traditional end product testing or an operation within a small range of controlled parameters. A high level of automation based on process models and hierarchical control concepts...

Cite
Sacher S, Poms J, Rehrl J, et al. PAT implementation for advanced process control in solid dosage manufacturing - A practical guide. Int J Pharm. 2021;613:121408doi: 10.1016/j.ijpharm.2021.121408.
Sacher, S., Poms, J., Rehrl, J., & Khinast, J. G. (2021). PAT implementation for advanced process control in solid dosage manufacturing - A practical guide. International journal of pharmaceutics, 613121408. https://doi.org/10.1016/j.ijpharm.2021.121408
Sacher, Stephan, et al. "PAT implementation for advanced process control in solid dosage manufacturing - A practical guide." International journal of pharmaceutics vol. 613 (2021): 121408. doi: https://doi.org/10.1016/j.ijpharm.2021.121408
Sacher S, Poms J, Rehrl J, Khinast JG. PAT implementation for advanced process control in solid dosage manufacturing - A practical guide. Int J Pharm. 2021 Dec 21;613:121408. doi: 10.1016/j.ijpharm.2021.121408. Epub 2021 Dec 21. PMID: 34952147.
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The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory.

Pharmacological reports : PR

Kambe Y, Yamauchi Y, Thanh Nguyen T, Thi Nguyen T, Ago Y, Shintani N, Hashimoto H, Yoshitake S, Yoshitake T, Kehr J, Kawamura N, Katsuura G, Kurihara T, Miyata A.
PMID: 33835466
Pharmacol Rep. 2021 Aug;73(4):1109-1121. doi: 10.1007/s43440-021-00222-6. Epub 2021 Apr 09.

BACKGROUND: Pituitary adenylate cyclase-activating polypeptide (PACAP) plays an essential role in the modulation of astrocyte functions. Although lactate secretion from astrocytes contributes to many forms of neuronal plasticity in the central nervous system, including fear learning and memory, the...

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Kambe Y, Yamauchi Y, Thanh Nguyen T, et al. The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory. Pharmacol Rep. 2021;73(4):1109-1121doi: 10.1007/s43440-021-00222-6.
Kambe, Y., Yamauchi, Y., Thanh Nguyen, T., Thi Nguyen, T., Ago, Y., Shintani, N., Hashimoto, H., Yoshitake, S., Yoshitake, T., Kehr, J., Kawamura, N., Katsuura, G., Kurihara, T., & Miyata, A. (2021). The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory. Pharmacological reports : PR, 73(4), 1109-1121. https://doi.org/10.1007/s43440-021-00222-6
Kambe, Yuki, et al. "The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory." Pharmacological reports : PR vol. 73,4 (2021): 1109-1121. doi: https://doi.org/10.1007/s43440-021-00222-6
Kambe Y, Yamauchi Y, Thanh Nguyen T, Thi Nguyen T, Ago Y, Shintani N, Hashimoto H, Yoshitake S, Yoshitake T, Kehr J, Kawamura N, Katsuura G, Kurihara T, Miyata A. The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory. Pharmacol Rep. 2021 Aug;73(4):1109-1121. doi: 10.1007/s43440-021-00222-6. Epub 2021 Apr 09. PMID: 33835466.
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Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic.

Journal of critical care

Díaz F, Kehr J, Cores C, Rubilar P, Medina T, Vargas C, Cruces P.
PMID: 34922313
J Crit Care. 2021 Dec 15;68:59-65. doi: 10.1016/j.jcrc.2021.12.004. Epub 2021 Dec 15.

PURPOSE: We aim to describe the action plan and clinical results of a COVID-19 unit for adult patient care in units intended for critically ill children, proposing a clinical/administrative framework.METHODS: We reviewed the preparedness of the PICU team before...

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Díaz F, Kehr J, Cores C, et al. Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic. J Crit Care. 2021;68:59-65doi: 10.1016/j.jcrc.2021.12.004.
Díaz, F., Kehr, J., Cores, C., Rubilar, P., Medina, T., Vargas, C., & Cruces, P. (2021). Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic. Journal of critical care, 6859-65. https://doi.org/10.1016/j.jcrc.2021.12.004
Díaz, Franco, et al. "Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic." Journal of critical care vol. 68 (2021): 59-65. doi: https://doi.org/10.1016/j.jcrc.2021.12.004
Díaz F, Kehr J, Cores C, Rubilar P, Medina T, Vargas C, Cruces P. Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic. J Crit Care. 2021 Dec 15;68:59-65. doi: 10.1016/j.jcrc.2021.12.004. Epub 2021 Dec 15. PMID: 34922313.
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In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy.

iScience

Yan SLS, Hwang IY, Kamenyeva O, Kehrl JH.
PMID: 31203185
iScience. 2019 Jun 28;16:283-297. doi: 10.1016/j.isci.2019.05.040. Epub 2019 May 30.

Actin is essential for many cellular processes including cell motility. Yet the organization of F-actin filaments during lymphocyte transendothelial migration (TEM) and interstitial migration have not been visualized. Here we report a high-resolution confocal intravital imaging technique with LifeAct-GFP...

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Yan SLS, Hwang IY, Kamenyeva O, et al. In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy. iScience. 2019;16:283-297doi: 10.1016/j.isci.2019.05.040.
Yan, S. L. S., Hwang, I. Y., Kamenyeva, O., & Kehrl, J. H. (2019). In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy. iScience, 16283-297. https://doi.org/10.1016/j.isci.2019.05.040
Yan, Serena L S, et al. "In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy." iScience vol. 16 (2019): 283-297. doi: https://doi.org/10.1016/j.isci.2019.05.040
Yan SLS, Hwang IY, Kamenyeva O, Kehrl JH. In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy. iScience. 2019 Jun 28;16:283-297. doi: 10.1016/j.isci.2019.05.040. Epub 2019 May 30. PMID: 31203185; PMCID: PMC6581778.
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Ipsilesional .

Brain communications

Watanabe H, Nosova O, Sarkisyan D, Andersen MS, Zhang M, Rorick-Kehn L, Clausen F, Gawel K, Kehr J, Hallberg M, Schouenborg J, Marklund N, Bakalkin G.
PMID: 33364602
Brain Commun. 2020 Dec 13;2(2):fcaa208. doi: 10.1093/braincomms/fcaa208. eCollection 2020.

Unilateral traumatic brain injury and stroke result in asymmetric postural and motor deficits including contralateral hemiplegia and hemiparesis. In animals, a localized unilateral brain injury recapitulates the human upper motor neuron syndrome in the formation of hindlimb postural asymmetry...

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Watanabe H, Nosova O, Sarkisyan D, et al. Ipsilesional . Brain Commun. 2020;2(2):fcaa208doi: 10.1093/braincomms/fcaa208.
Watanabe, H., Nosova, O., Sarkisyan, D., Andersen, M. S., Zhang, M., Rorick-Kehn, L., Clausen, F., Gawel, K., Kehr, J., Hallberg, M., Schouenborg, J., Marklund, N., & Bakalkin, G. (2020). Ipsilesional . Brain communications, 2(2), fcaa208. https://doi.org/10.1093/braincomms/fcaa208
Watanabe, Hiroyuki, et al. "Ipsilesional ." Brain communications vol. 2,2 (2020): fcaa208. doi: https://doi.org/10.1093/braincomms/fcaa208
Watanabe H, Nosova O, Sarkisyan D, Andersen MS, Zhang M, Rorick-Kehn L, Clausen F, Gawel K, Kehr J, Hallberg M, Schouenborg J, Marklund N, Bakalkin G. Ipsilesional . Brain Commun. 2020 Dec 13;2(2):fcaa208. doi: 10.1093/braincomms/fcaa208. eCollection 2020. PMID: 33364602; PMCID: PMC7749794.
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Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic.

Journal of critical care

Díaz F, Kehr J, Cores C, Rubilar P, Medina T, Vargas C, Cruces P.
PMID: 34922313
J Crit Care. 2021 Dec 15;68:59-65. doi: 10.1016/j.jcrc.2021.12.004. Epub 2021 Dec 15.

PURPOSE: We aim to describe the action plan and clinical results of a COVID-19 unit for adult patient care in units intended for critically ill children, proposing a clinical/administrative framework.METHODS: We reviewed the preparedness of the PICU team before...

Cite
Díaz F, Kehr J, Cores C, et al. Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic. J Crit Care. 2021;68:59-65doi: 10.1016/j.jcrc.2021.12.004.
Díaz, F., Kehr, J., Cores, C., Rubilar, P., Medina, T., Vargas, C., & Cruces, P. (2021). Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic. Journal of critical care, 6859-65. https://doi.org/10.1016/j.jcrc.2021.12.004
Díaz, Franco, et al. "Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic." Journal of critical care vol. 68 (2021): 59-65. doi: https://doi.org/10.1016/j.jcrc.2021.12.004
Díaz F, Kehr J, Cores C, Rubilar P, Medina T, Vargas C, Cruces P. Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic. J Crit Care. 2021 Dec 15;68:59-65. doi: 10.1016/j.jcrc.2021.12.004. Epub 2021 Dec 15. PMID: 34922313.
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Normal and obstructive breathing physiology during sleep.

Sleep & breathing = Schlaf & Atmung

Kerl J, Noeke P, Heyse D, Dellweg D.
PMID: 33128177
Sleep Breath. 2021 Sep;25(3):1335-1341. doi: 10.1007/s11325-020-02217-8. Epub 2020 Oct 30.

PURPOSE: To estimate the severity of flow limitation in patients with OSA, the number of breaths with flattened inspiratory flow curves should be identified. Attempts to do a quantitative analysis of the flattening degree for all breaths in a...

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Kerl J, Noeke P, Heyse D, et al. Normal and obstructive breathing physiology during sleep. Sleep Breath. 2020;25(3):1335-1341doi: 10.1007/s11325-020-02217-8.
Kerl, J., Noeke, P., Heyse, D., & Dellweg, D. (2021). Normal and obstructive breathing physiology during sleep. Sleep & breathing = Schlaf & Atmung, 25(3), 1335-1341. https://doi.org/10.1007/s11325-020-02217-8
Kerl, Jens, et al. "Normal and obstructive breathing physiology during sleep." Sleep & breathing = Schlaf & Atmung vol. 25,3 (2021): 1335-1341. doi: https://doi.org/10.1007/s11325-020-02217-8
Kerl J, Noeke P, Heyse D, Dellweg D. Normal and obstructive breathing physiology during sleep. Sleep Breath. 2021 Sep;25(3):1335-1341. doi: 10.1007/s11325-020-02217-8. Epub 2020 Oct 30. PMID: 33128177.
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Moment in surgery.

Surgery

Kehl JE.
PMID: 27817872
Surgery. 2017 May;161(5):1458. doi: 10.1016/j.surg.2016.09.001. Epub 2016 Nov 03.

No abstract available.

Cite
Kehl JE. Moment in surgery. Surgery. 2016;161(5):1458doi: 10.1016/j.surg.2016.09.001.
Kehl, J. E. (2017). Moment in surgery. Surgery, 161(5), 1458. https://doi.org/10.1016/j.surg.2016.09.001
Kehl, Jack E. "Moment in surgery." Surgery vol. 161,5 (2017): 1458. doi: https://doi.org/10.1016/j.surg.2016.09.001
Kehl JE. Moment in surgery. Surgery. 2017 May;161(5):1458. doi: 10.1016/j.surg.2016.09.001. Epub 2016 Nov 03. PMID: 27817872.
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Feelings-of-Warmth Increase More Abruptly for Verbal Riddles Solved With in Contrast to Without Aha! Experience.

Frontiers in psychology

Kizilirmak JM, Serger V, Kehl J, Öllinger M, Folta-Schoofs K, Richardson-Klavehn A.
PMID: 30150953
Front Psychol. 2018 Aug 13;9:1404. doi: 10.3389/fpsyg.2018.01404. eCollection 2018.

When we are confronted with a new problem, we typically try to apply strategies that have worked in the past and which usually lead closer to the solution incrementally. However, sometimes, either during a problem-solving attempt that does not...

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Kizilirmak JM, Serger V, Kehl J, et al. Feelings-of-Warmth Increase More Abruptly for Verbal Riddles Solved With in Contrast to Without Aha! Experience. Front Psychol. 2018;9:1404doi: 10.3389/fpsyg.2018.01404.
Kizilirmak, J. M., Serger, V., Kehl, J., Öllinger, M., Folta-Schoofs, K., & Richardson-Klavehn, A. (2018). Feelings-of-Warmth Increase More Abruptly for Verbal Riddles Solved With in Contrast to Without Aha! Experience. Frontiers in psychology, 91404. https://doi.org/10.3389/fpsyg.2018.01404
Kizilirmak, Jasmin M, et al. "Feelings-of-Warmth Increase More Abruptly for Verbal Riddles Solved With in Contrast to Without Aha! Experience." Frontiers in psychology vol. 9 (2018): 1404. doi: https://doi.org/10.3389/fpsyg.2018.01404
Kizilirmak JM, Serger V, Kehl J, Öllinger M, Folta-Schoofs K, Richardson-Klavehn A. Feelings-of-Warmth Increase More Abruptly for Verbal Riddles Solved With in Contrast to Without Aha! Experience. Front Psychol. 2018 Aug 13;9:1404. doi: 10.3389/fpsyg.2018.01404. eCollection 2018. PMID: 30150953; PMCID: PMC6099077.
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Protocol: optimisation of a grafting protocol for oilseed rape (Brassica napus) for studying long-distance signalling.

Plant methods

Ostendorp A, Pahlow S, Deke J, Thieß M, Kehr J.
PMID: 27019668
Plant Methods. 2016 Mar 25;12:22. doi: 10.1186/s13007-016-0122-x. eCollection 2016.

BACKGROUND: Grafting is a well-established technique for studying long-distance transport and signalling processes in higher plants. While oilseed rape has been the subject of comprehensive analyses of xylem and phloem sap to identify macromolecules potentially involved in long-distance information...

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Ostendorp A, Pahlow S, Deke J, et al. Protocol: optimisation of a grafting protocol for oilseed rape (Brassica napus) for studying long-distance signalling. Plant Methods. 2016;12:22doi: 10.1186/s13007-016-0122-x.
Ostendorp, A., Pahlow, S., Deke, J., Thieß, M., & Kehr, J. (2016). Protocol: optimisation of a grafting protocol for oilseed rape (Brassica napus) for studying long-distance signalling. Plant methods, 1222. https://doi.org/10.1186/s13007-016-0122-x
Ostendorp, Anna, et al. "Protocol: optimisation of a grafting protocol for oilseed rape (Brassica napus) for studying long-distance signalling." Plant methods vol. 12 (2016): 22. doi: https://doi.org/10.1186/s13007-016-0122-x
Ostendorp A, Pahlow S, Deke J, Thieß M, Kehr J. Protocol: optimisation of a grafting protocol for oilseed rape (Brassica napus) for studying long-distance signalling. Plant Methods. 2016 Mar 25;12:22. doi: 10.1186/s13007-016-0122-x. eCollection 2016. PMID: 27019668; PMCID: PMC4807576.
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Stabilized Vanadium Catalyst for Olefin Polymerization by Site Isolation in a Metal-Organic Framework.

Angewandte Chemie (International ed. in English)

Comito RJ, Wu Z, Zhang G, Lawrence JA, Korzyński MD, Kehl JA, Miller JT, Dincă M.
PMID: 29688609
Angew Chem Int Ed Engl. 2018 Jul 02;57(27):8135-8139. doi: 10.1002/anie.201803642. Epub 2018 May 30.

Vanadium catalysts offer unique selectivity in olefin polymerization, yet are underutilized industrially owing to their poor stability and productivity. Reported here is the immobilization of vanadium by cation exchange in MFU-4l, thus providing a metal-organic framework (MOF) with vanadium...

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Comito RJ, Wu Z, Zhang G, et al. Stabilized Vanadium Catalyst for Olefin Polymerization by Site Isolation in a Metal-Organic Framework. Angew Chem Int Ed Engl. 2018;57(27):8135-8139doi: 10.1002/anie.201803642.
Comito, R. J., Wu, Z., Zhang, G., Lawrence, J. A., Korzyński, M. D., Kehl, J. A., Miller, J. T., & Dincă, M. (2018). Stabilized Vanadium Catalyst for Olefin Polymerization by Site Isolation in a Metal-Organic Framework. Angewandte Chemie (International ed. in English), 57(27), 8135-8139. https://doi.org/10.1002/anie.201803642
Comito, Robert J, et al. "Stabilized Vanadium Catalyst for Olefin Polymerization by Site Isolation in a Metal-Organic Framework." Angewandte Chemie (International ed. in English) vol. 57,27 (2018): 8135-8139. doi: https://doi.org/10.1002/anie.201803642
Comito RJ, Wu Z, Zhang G, Lawrence JA, Korzyński MD, Kehl JA, Miller JT, Dincă M. Stabilized Vanadium Catalyst for Olefin Polymerization by Site Isolation in a Metal-Organic Framework. Angew Chem Int Ed Engl. 2018 Jul 02;57(27):8135-8139. doi: 10.1002/anie.201803642. Epub 2018 May 30. PMID: 29688609.
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Showing 13 to 24 of 108 entries