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Showing 1117 to 1126 of 1126 entries
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Adrenal Vein Cortisol to Metanephrine Ratio for Localizing ACTH-Independent Cortisol-Producing Adenoma: A Case Report.

Journal of the Endocrine Society

Raj R, Kern PA, Ghanta N, Uy EM, Asadipooya K.
PMID: 33644621
J Endocr Soc. 2021 Jan 25;5(4):bvab009. doi: 10.1210/jendso/bvab009. eCollection 2021 Apr 01.

CONTEXT: Finding the source of adrenocorticotropic hormone (ACTH)-independent cortisol-producing adenoma in the patients with subclinical Cushing syndrome (SCS) and bilateral adrenal nodules is sometimes challenging. Computed tomography (CT) and positron emission tomography are helpful, but adrenal venous sampling (AVS)...

Advances in the treatment, diagnosis, control and scientific understanding of taeniid cestode parasite infections over the past 50 years.

International journal for parasitology

Lightowlers MW, Gasser RB, Hemphill A, Romig T, Tamarozzi F, Deplazes P, Torgerson PR, Garcia HH, Kern P.
PMID: 34757089
Int J Parasitol. 2021 Dec;51(13):1167-1192. doi: 10.1016/j.ijpara.2021.10.003. Epub 2021 Oct 30.

In the past 50 years, enormous progress has been made in the diagnosis, treatment and control of taeniid cestode infections/diseases and in the scientific understanding thereof. Most interest in this group of parasites stems from the serious diseases that...

Age and Sex Influence Mitochondria and Cardiac Health in Offspring Exposed to Maternal Glucolipotoxicity.

iScience

Louwagie EJ, Larsen TD, Wachal AL, Gandy TCT, Eclov JA, Rideout TC, Kern KA, Cain JT, Anderson RH, Mdaki KS, Baack ML.
PMID: 33225249
iScience. 2020 Oct 28;23(11):101746. doi: 10.1016/j.isci.2020.101746. eCollection 2020 Nov 20.

Infants of diabetic mothers are at risk of cardiomyopathy at birth and myocardial infarction in adulthood, but prevention is hindered because mechanisms remain unknown. We previously showed that maternal glucolipotoxicity increases the risk of cardiomyopathy and mortality in newborn...

Muscle transcriptional networks linked to resistance exercise training hypertrophic response heterogeneity.

Physiological genomics

Lavin KM, Bell MB, McAdam JS, Peck BD, Walton RG, Windham ST, Tuggle SC, Long DE, Kern PA, Peterson CA, Bamman MM.
PMID: 33870722
Physiol Genomics. 2021 May 01;53(5):206-221. doi: 10.1152/physiolgenomics.00154.2020. Epub 2021 Apr 19.

The skeletal muscle hypertrophic response to resistance exercise training (RT) is highly variable across individuals. The molecular underpinnings of this heterogeneity are unclear. This study investigated transcriptional networks linked to RT-induced muscle hypertrophy, classified as

The influence of labor epidural analgesia on maternal, uteroplacental and fetoplacental hemodynamics in normotensive parturients: a prospective observational study.

International journal of obstetric anesthesia

Gude P, Kaci CSB, Sieker M, Vogelsang H, Bellgardt M, Herzog-Niescery J, Weber TP, Weber J, Teubner S, Kern P.
PMID: 33298344
Int J Obstet Anesth. 2021 Feb;45:83-89. doi: 10.1016/j.ijoa.2020.10.011. Epub 2020 Nov 04.

BACKGROUND: Epidural analgesia provides sufficient analgesia during labor but can cause hypotension despite various prophylactic measures. We studied its effects on pre-placental, fetoplacental, and fetal hemodynamics using Doppler ultrasound. The primary endpoint was the pulsatility index of the umbilical...

Increased estimated fat-free mass and fat mass associated with improved clinical outcome in heart failure.

European journal of clinical investigation

Gotsman I, Keren A, Amir O, Zwas DR.
PMID: 34293203
Eur J Clin Invest. 2021 Jul 22;e13655. doi: 10.1111/eci.13655. Epub 2021 Jul 22.

BACKGROUND: Increased weight measured by body mass index is associated with better clinical outcomes in heart failure (HF). The effect of specific components of body mass on outcome is limited. We evaluated the impact of fat-free mass and fat...

Identification and optimization of a novel series of selective PIP5K inhibitors.

Bioorganic & medicinal chemistry

Andrews DM, Cartic S, Cosulich S, Divecha N, Faulder P, Flemington V, Kern O, Kettle JG, MacDonald E, McKelvie J, Pike KG, Roberts B, Rowlinson R, Smith JM, Stockley M, Swarbrick ME, Treinies I, Waring MJ.
PMID: 34922306
Bioorg Med Chem. 2022 Jan 15;54:116557. doi: 10.1016/j.bmc.2021.116557. Epub 2021 Dec 12.

Phosphatidyl inositol (4,5)-bisphosphate (PI(4,5)P

Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease.

Hepatology (Baltimore, Md.)

Alexopoulos AS, Crowley MJ, Wang Y, Moylan CA, Guy CD, Henao R, Piercy DL, Seymour KA, Sudan R, Portenier DD, Diehl AM, Coviello AD, Abdelmalek MF.
PMID: 33724511
Hepatology. 2021 Sep;74(3):1220-1233. doi: 10.1002/hep.31806. Epub 2021 Jun 02.

BACKGROUND AND AIMS: Whether glycemic control, as opposed to diabetes status, is associated with the severity of NAFLD is open for study. We aimed to evaluate whether degree of glycemic control in the years preceding liver biopsy predicts the...

Deep learning-a first meta-survey of selected reviews across scientific disciplines, their commonalities, challenges and research impact.

PeerJ. Computer science

Egger J, Pepe A, Gsaxner C, Jin Y, Li J, Kern R.
PMID: 34901429
PeerJ Comput Sci. 2021 Nov 17;7:e773. doi: 10.7717/peerj-cs.773. eCollection 2021.

Deep learning belongs to the field of artificial intelligence, where machines perform tasks that typically require some kind of human intelligence. Deep learning tries to achieve this by drawing inspiration from the learning of a human brain. Similar to...

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Glikson M, Nielsen JC, Kronborg MB, Michowitz Y, Auricchio A, Barbash IM, Barrabés JA, Boriani G, Braunschweig F, Brignole M, Burri H, Coats AJS, Deharo JC, Delgado V, Diller GP, Israel CW, Keren A, Knops RE, Kotecha D, Leclercq C, Merkely B, Starck C, Thylén I, Tolosana JM.
PMID: 34455427
Europace. 2021 Aug 29; doi: 10.1093/europace/euab232. Epub 2021 Aug 29.

No abstract available.

Showing 1117 to 1126 of 1126 entries