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Showing 25 to 36 of 184 entries
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G-quadruplex microspheres-based optical RNA biosensor for arthropod-borne virus pathogen detection: A proof-of-concept with dengue serotype 2.

International journal of biological macromolecules

Jamaluddin ND, Mazlan NF, Tan LL, Yusof NYM, Khalid B.
PMID: 34922999
Int J Biol Macromol. 2021 Dec 16;199:1-9. doi: 10.1016/j.ijbiomac.2021.12.047. Epub 2021 Dec 16.

Dengue virus (DENV) is a positive-sense single-stranded RNA virus and that the detection of viral RNA itself is highly desirable, which can be achieved by using RNA biosensor diagnostic method. Herein, acrylic micropolymer-based optical RNA biosensor was developed by...

Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models.

Scientific reports

Schulten HJ, Al-Adwani F, Saddeq HAB, Alkhatabi H, Alganmi N, Karim S, Hussein D, Al-Ghamdi KB, Jamal A, Al-Maghrabi J, Al-Qahtani MH.
PMID: 34997121
Sci Rep. 2022 Jan 07;12(1):57. doi: 10.1038/s41598-021-04214-7.

Mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 are oncogenic drivers to a variable extent in several tumors, including gliomas, acute myeloid leukemia (AML), cholangiocarcinoma, melanoma, and thyroid carcinoma. The pathobiological effects of these mutations vary considerably, impeding the...

Direct Blow-Spinning of Nanofibers on a Window Screen for Highly Efficient PM.

Nano letters

Khalid B, Bai X, Wei H, Huang Y, Wu H, Cui Y.
PMID: 28027642
Nano Lett. 2017 Feb 08;17(2):1140-1148. doi: 10.1021/acs.nanolett.6b04771. Epub 2017 Jan 04.

Particulate matter (PM) pollution has caused many serious public health issues. Whereas indoor air protection usually relies on expensive and energy-consuming filtering devices, direct PM filtration by window screens has attracted increasing attention. Recently, electrospun polymer nanofiber networks have...

Herpes Simplex Virus Type 1 Infection Disturbs the Mitochondrial Network, Leading to Type I Interferon Production through the RNA Polymerase III/RIG-I Pathway.

mBio

Berry N, Suspène R, Caval V, Khalfi P, Beauclair G, Rigaud S, Blanc H, Vignuzzi M, Wain-Hobson S, Vartanian JP.
PMID: 34809467
mBio. 2021 Nov 23;e0255721. doi: 10.1128/mBio.02557-21. Epub 2021 Nov 23.

Viruses have evolved a plethora of mechanisms to impair host innate immune responses. Herpes simplex virus type 1 (HSV-1), a double-stranded linear DNA virus, impairs the mitochondrial network and dynamics predominantly through the

StarD13 negatively regulates invadopodia formation and invasion in high-grade serous (HGS) ovarian adenocarcinoma cells by inhibiting Cdc42.

European journal of cell biology

Abdellatef S, Fakhoury I, Haddad MA, Jaafar L, Maalouf H, Hanna S, Khalil B, El Masri Z, Hodgson L, El-Sibai M.
PMID: 34958986
Eur J Cell Biol. 2021 Dec 21;101(1):151197. doi: 10.1016/j.ejcb.2021.151197. Epub 2021 Dec 21.

Metastasis remains the main challenge to overcome for treating ovarian cancers. In this study, we investigate the potential role of the Cdc42 GAP StarD13 in the modulation of cell motility, invasion in ovarian cancer cells. StarD13 depletion does not...

[The resource support of medical organizations providing medical care in twenty-four-hour hospital under new corona-virus infection COVID-19].

Problemy sotsial'noi gigieny, zdravookhraneniia i istorii meditsiny

Orlov SA, Khalfin RA, Aleksandrova OY, Stolbov AP.
PMID: 34665533
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med. 2021 Sep;29(5):1034-1039. doi: 10.32687/0869-866X-2021-29-5-1034-1039.

The article considers, on the basis of application of modern information analytical systems, the sequential stages of analysis and evaluation of indices of resource support of medical organizations and technological process of medical care provision. The results of the...

RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury.

Acta neuropathologica communications

Wehn AC, Khalin I, Duering M, Hellal F, Culmsee C, Vandenabeele P, Plesnila N, Terpolilli NA.
PMID: 34404478
Acta Neuropathol Commun. 2021 Aug 17;9(1):138. doi: 10.1186/s40478-021-01236-0.

Traumatic brain injury (TBI) causes acute and subacute tissue damage, but is also associated with chronic inflammation and progressive loss of brain tissue months and years after the initial event. The trigger and the subsequent molecular mechanisms causing chronic...

Effect of Bioactive Phytochemicals from .

Plants (Basel, Switzerland)

Yarmolinsky L, Budovsky A, Yarmolinsky L, Khalfin B, Glukhman V, Ben-Shabat S.
PMID: 31888128
Plants (Basel). 2019 Dec 16;8(12). doi: 10.3390/plants8120609.

No abstract available.

Do proton pump inhibitors modulate the efficacy of anti-PD-1/PD-L1 therapy? A retrospective study.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Mukherjee S, Ibrahimi S, Khalid B, Roman D, Zhao D, Aljumaily R.
PMID: 29690815
J Oncol Pharm Pract. 2019 Apr;25(3):762-764. doi: 10.1177/1078155218771152. Epub 2018 Apr 24.

No abstract available.

Economics of cancer biomarkers.

Personalized medicine

Schneider JE, Sidhu MK, Doucet C, Kiss N, Ohsfeldt RL, Chalfin D.
PMID: 29776231
Per Med. 2012 Nov;9(8):829-837. doi: 10.2217/pme.12.87.

Cancer accounts for approximately 13% of all deaths worldwide, and in 2010 the estimated total cost of cancer in the USA was more than US$263 billion. Biomarker use for screening, monitoring, diagnosis and treatment optimization has the potential to...

Corrigendum to "A Mass of Pancreatic and Gastric Heterotopia Causing a Small Bowel Obstruction in a 61-Year-Old Male".

Case reports in gastrointestinal medicine

Alfreijat M, Khalil B, Jackobs J, Anderson W, Eschbacher J.
PMID: 29082048
Case Rep Gastrointest Med. 2017;2017:2536163. doi: 10.1155/2017/2536163. Epub 2017 Sep 24.

[This corrects the article DOI: 10.1155/2017/3126108.].

SiOx Nanodandelion by Laser Ablation for Anode of Lithium-Ion Battery.

Small (Weinheim an der Bergstrasse, Germany)

Luo X, Zhang H, Pan W, Gong J, Khalid B, Zhong M, Wu H.
PMID: 26449629
Small. 2015 Dec 02;11(45):6009-12. doi: 10.1002/smll.201502539. Epub 2015 Oct 09.

Silicon-based nanoparticles with unique "nanodandelion" structures are synthesized by a simple and efficient laser ablation method. Such material can be used as a stable anode for Li-ion batteries with a high capacity of ≈1500 mAh g(-1) and for more...

Showing 25 to 36 of 184 entries