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Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease.

The world journal of men's health

Song KM, Chung DY, Choi MJ, Ghatak K, Minh NN, Limanjaya A, Kwon MH, Ock J, Yin GN, Kim DK, Ryu JK, Suh JK.
PMID: 31496148
World J Mens Health. 2020 Oct;38(4):552-563. doi: 10.5534/wjmh.190071. Epub 2019 Aug 27.

PURPOSE: To examine the therapeutic effect of Vactosertib, a small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor (activin receptor-like kinase-5, ALK5), in an experimental model of Peyronie's disease (PD) and determining anti-fibrotic mechanisms of Vactosertib in...

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Song KM, Chung DY, Choi MJ, et al. Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease. World J Mens Health. 2019;38(4):552-563doi: 10.5534/wjmh.190071.
Song, K. M., Chung, D. Y., Choi, M. J., Ghatak, K., Minh, N. N., Limanjaya, A., Kwon, M. H., Ock, J., Yin, G. N., Kim, D. K., Ryu, J. K., & Suh, J. K. (2020). Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease. The world journal of men's health, 38(4), 552-563. https://doi.org/10.5534/wjmh.190071
Song, Kang Moon, et al. "Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease." The world journal of men's health vol. 38,4 (2020): 552-563. doi: https://doi.org/10.5534/wjmh.190071
Song KM, Chung DY, Choi MJ, Ghatak K, Minh NN, Limanjaya A, Kwon MH, Ock J, Yin GN, Kim DK, Ryu JK, Suh JK. Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease. World J Mens Health. 2020 Oct;38(4):552-563. doi: 10.5534/wjmh.190071. Epub 2019 Aug 27. PMID: 31496148; PMCID: PMC7502315.
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Physicochemical and Pharmacokinetic Analysis of Anacardic Acid Derivatives.

ACS omega

Zafar F, Gupta A, Thangavel K, Khatana K, Sani AA, Ghosal A, Tandon P, Nishat N.
PMID: 32226883
ACS Omega. 2020 Mar 13;5(11):6021-6030. doi: 10.1021/acsomega.9b04398. eCollection 2020 Mar 24.

Anacardic acid (AA) and its derivatives are well-known for their therapeutic applications ranging from antitumor, antibacterial, antioxidant, anticancer, and so forth. However, their poor pharmacokinetic and safety properties create significant hurdles in the formulation of the final drug molecule....

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Zafar F, Gupta A, Thangavel K, et al. Physicochemical and Pharmacokinetic Analysis of Anacardic Acid Derivatives. ACS Omega. 2020;5(11):6021-6030doi: 10.1021/acsomega.9b04398.
Zafar, F., Gupta, A., Thangavel, K., Khatana, K., Sani, A. A., Ghosal, A., Tandon, P., & Nishat, N. (2020). Physicochemical and Pharmacokinetic Analysis of Anacardic Acid Derivatives. ACS omega, 5(11), 6021-6030. https://doi.org/10.1021/acsomega.9b04398
Zafar, Fahmina, et al. "Physicochemical and Pharmacokinetic Analysis of Anacardic Acid Derivatives." ACS omega vol. 5,11 (2020): 6021-6030. doi: https://doi.org/10.1021/acsomega.9b04398
Zafar F, Gupta A, Thangavel K, Khatana K, Sani AA, Ghosal A, Tandon P, Nishat N. Physicochemical and Pharmacokinetic Analysis of Anacardic Acid Derivatives. ACS Omega. 2020 Mar 13;5(11):6021-6030. doi: 10.1021/acsomega.9b04398. eCollection 2020 Mar 24. PMID: 32226883; PMCID: PMC7098041.
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Assessment Methods of Post-stroke Gait: A Scoping Review of Technology-Driven Approaches to Gait Characterization and Analysis.

Frontiers in neurology

Mohan DM, Khandoker AH, Wasti SA, Ismail Ibrahim Ismail Alali S, Jelinek HF, Khalaf K.
PMID: 34168608
Front Neurol. 2021 Jun 08;12:650024. doi: 10.3389/fneur.2021.650024. eCollection 2021.

No abstract available.

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Mohan DM, Khandoker AH, Wasti SA, et al. Assessment Methods of Post-stroke Gait: A Scoping Review of Technology-Driven Approaches to Gait Characterization and Analysis. Front Neurol. 2021;12:650024doi: 10.3389/fneur.2021.650024.
Mohan, D. M., Khandoker, A. H., Wasti, S. A., Ismail Ibrahim Ismail Alali, S., Jelinek, H. F., & Khalaf, K. (2021). Assessment Methods of Post-stroke Gait: A Scoping Review of Technology-Driven Approaches to Gait Characterization and Analysis. Frontiers in neurology, 12650024. https://doi.org/10.3389/fneur.2021.650024
Mohan, Dhanya Menoth, et al. "Assessment Methods of Post-stroke Gait: A Scoping Review of Technology-Driven Approaches to Gait Characterization and Analysis." Frontiers in neurology vol. 12 (2021): 650024. doi: https://doi.org/10.3389/fneur.2021.650024
Mohan DM, Khandoker AH, Wasti SA, Ismail Ibrahim Ismail Alali S, Jelinek HF, Khalaf K. Assessment Methods of Post-stroke Gait: A Scoping Review of Technology-Driven Approaches to Gait Characterization and Analysis. Front Neurol. 2021 Jun 08;12:650024. doi: 10.3389/fneur.2021.650024. eCollection 2021. PMID: 34168608; PMCID: PMC8217618.
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Wearables in the home-based assessment of abnormal movements in Parkinson's disease: a systematic review of the literature.

Journal of neurology

Ancona S, Faraci FD, Khatab E, Fiorillo L, Gnarra O, Nef T, Bassetti CLA, Bargiotas P.
PMID: 33409603
J Neurol. 2022 Jan;269(1):100-110. doi: 10.1007/s00415-020-10350-3. Epub 2021 Jan 06.

At present, the standard practices for home-based assessments of abnormal movements in Parkinson's disease (PD) are based either on subjective tools or on objective measures that often fail to capture day-to-day fluctuations and long-term information in real-life conditions in...

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Ancona S, Faraci FD, Khatab E, et al. Wearables in the home-based assessment of abnormal movements in Parkinson's disease: a systematic review of the literature. J Neurol. 2021;269(1):100-110doi: 10.1007/s00415-020-10350-3.
Ancona, S., Faraci, F. D., Khatab, E., Fiorillo, L., Gnarra, O., Nef, T., Bassetti, C. L. A., & Bargiotas, P. (2022). Wearables in the home-based assessment of abnormal movements in Parkinson's disease: a systematic review of the literature. Journal of neurology, 269(1), 100-110. https://doi.org/10.1007/s00415-020-10350-3
Ancona, Stefania, et al. "Wearables in the home-based assessment of abnormal movements in Parkinson's disease: a systematic review of the literature." Journal of neurology vol. 269,1 (2022): 100-110. doi: https://doi.org/10.1007/s00415-020-10350-3
Ancona S, Faraci FD, Khatab E, Fiorillo L, Gnarra O, Nef T, Bassetti CLA, Bargiotas P. Wearables in the home-based assessment of abnormal movements in Parkinson's disease: a systematic review of the literature. J Neurol. 2022 Jan;269(1):100-110. doi: 10.1007/s00415-020-10350-3. Epub 2021 Jan 06. PMID: 33409603.
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Mixed NHC-thiolato complexes of palladium: understanding the formation of di-.

Dalton transactions (Cambridge, England : 2003)

Huynh HV, Ong HL, Ghatak K.
PMID: 34853842
Dalton Trans. 2021 Dec 14;50(48):18118-18127. doi: 10.1039/d1dt03714e.

The preference for the formation of mono-

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Huynh HV, Ong HL, Ghatak K. Mixed NHC-thiolato complexes of palladium: understanding the formation of di-. Dalton Trans. 2021;50(48):18118-18127doi: 10.1039/d1dt03714e.
Huynh, H. V., Ong, H. L., & Ghatak, K. (2021). Mixed NHC-thiolato complexes of palladium: understanding the formation of di-. Dalton transactions (Cambridge, England : 2003), 50(48), 18118-18127. https://doi.org/10.1039/d1dt03714e
Huynh, Han Vinh, et al. "Mixed NHC-thiolato complexes of palladium: understanding the formation of di-." Dalton transactions (Cambridge, England : 2003) vol. 50,48 (2021): 18118-18127. doi: https://doi.org/10.1039/d1dt03714e
Huynh HV, Ong HL, Ghatak K. Mixed NHC-thiolato complexes of palladium: understanding the formation of di-. Dalton Trans. 2021 Dec 14;50(48):18118-18127. doi: 10.1039/d1dt03714e. PMID: 34853842.
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KCNV2-Associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints-KCNV2 Study Group Report 2.

American journal of ophthalmology

Georgiou M, Fujinami K, Vincent A, Nasser F, Khateb S, Vargas ME, Thiadens AAHJ, de Carvalho ER, Nguyen XT, De Guimarães TAC, Robson AG, Mahroo OA, Pontikos N, Arno G, Fujinami-Yokokawa Y, Leo SM, Liu X, Tsunoda K, Hayashi T, Jimenez-Rolando B, Martin-Merida MI, Avila-Fernandez A, Carreño E, Garcia-Sandoval B, Ayuso C, Sharon D, Kohl S, Huckfeldt RM, Boon CJF, Banin E, Pennesi ME, Wissinger B, Webster AR, Héon E, Khan AO, Zrenner E, Michaelides M.
PMID: 33737031
Am J Ophthalmol. 2021 Oct;230:1-11. doi: 10.1016/j.ajo.2021.03.004. Epub 2021 Mar 15.

PURPOSE: To describe the detailed retinal phenotype of KCNV2-associated retinopathy.STUDY DESIGN: Multicenter international retrospective case series.METHODS: Review of retinal imaging including fundus autofluorescence (FAF) and optical coherence tomography (OCT), including qualitative and quantitative analyses.RESULTS: Three distinct macular FAF features...

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Georgiou M, Fujinami K, Vincent A, et al. KCNV2-Associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints-KCNV2 Study Group Report 2. Am J Ophthalmol. 2021;230:1-11doi: 10.1016/j.ajo.2021.03.004.
Georgiou, M., Fujinami, K., Vincent, A., Nasser, F., Khateb, S., Vargas, M. E., Thiadens, A. A. H. J., de Carvalho, E. R., Nguyen, X. T., De Guimarães, T. A. C., Robson, A. G., Mahroo, O. A., Pontikos, N., Arno, G., Fujinami-Yokokawa, Y., Leo, S. M., Liu, X., Tsunoda, K., Hayashi, T., Jimenez-Rolando, B., Martin-Merida, M. I., Avila-Fernandez, A., Carreño, E., Garcia-Sandoval, B., Ayuso, C., Sharon, D., Kohl, S., Huckfeldt, R. M., Boon, C. J. F., Banin, E., Pennesi, M. E., Wissinger, B., Webster, A. R., Héon, E., Khan, A. O., Zrenner, E., & Michaelides, M. (2021). KCNV2-Associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints-KCNV2 Study Group Report 2. American journal of ophthalmology, 2301-11. https://doi.org/10.1016/j.ajo.2021.03.004
Georgiou, Michalis, et al. "KCNV2-Associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints-KCNV2 Study Group Report 2." American journal of ophthalmology vol. 230 (2021): 1-11. doi: https://doi.org/10.1016/j.ajo.2021.03.004
Georgiou M, Fujinami K, Vincent A, Nasser F, Khateb S, Vargas ME, Thiadens AAHJ, de Carvalho ER, Nguyen XT, De Guimarães TAC, Robson AG, Mahroo OA, Pontikos N, Arno G, Fujinami-Yokokawa Y, Leo SM, Liu X, Tsunoda K, Hayashi T, Jimenez-Rolando B, Martin-Merida MI, Avila-Fernandez A, Carreño E, Garcia-Sandoval B, Ayuso C, Sharon D, Kohl S, Huckfeldt RM, Boon CJF, Banin E, Pennesi ME, Wissinger B, Webster AR, Héon E, Khan AO, Zrenner E, Michaelides M. KCNV2-Associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints-KCNV2 Study Group Report 2. Am J Ophthalmol. 2021 Oct;230:1-11. doi: 10.1016/j.ajo.2021.03.004. Epub 2021 Mar 15. PMID: 33737031; PMCID: PMC8710866.
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Protective effects of melatonin and L-carnitine against methotrexate-induced toxicity in isolated rat hepatocytes.

Naunyn-Schmiedeberg's archives of pharmacology

Khatab LA, Abdel-Raheem IT, Ghoneim AI.
PMID: 34821957
Naunyn Schmiedebergs Arch Pharmacol. 2022 Jan;395(1):87-97. doi: 10.1007/s00210-021-02176-1. Epub 2021 Nov 25.

The present study was designed to evaluate the possible protective effects of melatonin (MEL) and/or L-carnitine (L-CAR) against methotrexate (MTX)-induced toxicity in isolated rat hepatocytes. Hepatocytes were prepared using collagenase techniques of perfusion and digestion of rat liver. Trypan...

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Khatab LA, Abdel-Raheem IT, Ghoneim AI. Protective effects of melatonin and L-carnitine against methotrexate-induced toxicity in isolated rat hepatocytes. Naunyn Schmiedebergs Arch Pharmacol. 2021;395(1):87-97doi: 10.1007/s00210-021-02176-1.
Khatab, L. A., Abdel-Raheem, I. T., & Ghoneim, A. I. (2022). Protective effects of melatonin and L-carnitine against methotrexate-induced toxicity in isolated rat hepatocytes. Naunyn-Schmiedeberg's archives of pharmacology, 395(1), 87-97. https://doi.org/10.1007/s00210-021-02176-1
Khatab, Lamiaa A, et al. "Protective effects of melatonin and L-carnitine against methotrexate-induced toxicity in isolated rat hepatocytes." Naunyn-Schmiedeberg's archives of pharmacology vol. 395,1 (2022): 87-97. doi: https://doi.org/10.1007/s00210-021-02176-1
Khatab LA, Abdel-Raheem IT, Ghoneim AI. Protective effects of melatonin and L-carnitine against methotrexate-induced toxicity in isolated rat hepatocytes. Naunyn Schmiedebergs Arch Pharmacol. 2022 Jan;395(1):87-97. doi: 10.1007/s00210-021-02176-1. Epub 2021 Nov 25. PMID: 34821957.
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Evaluating Awareness and Practices Towards Diabetes and Diabetic Retinopathy in Adult Patients Attending the Eye Clinic in a Tertiary Academic Hospital in Jordan.

Clinical ophthalmology (Auckland, N.Z.)

Khatib F, Abu Tarboush N, Abu-Yaghi N, Alazzam M, Al-Ani A, Mafrachi B.
PMID: 33814898
Clin Ophthalmol. 2021 Mar 26;15:1309-1316. doi: 10.2147/OPTH.S299711. eCollection 2021.

AIM AND BACKGROUND: Awareness of diabetes mellitus (DM) and its complications, particularly diabetic retinopathy (DR), is one of the main factors of early detection and improved management. This study aims to assess the level of awareness of DM type...

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Khatib F, Abu Tarboush N, Abu-Yaghi N, et al. Evaluating Awareness and Practices Towards Diabetes and Diabetic Retinopathy in Adult Patients Attending the Eye Clinic in a Tertiary Academic Hospital in Jordan. Clin Ophthalmol. 2021;15:1309-1316doi: 10.2147/OPTH.S299711.
Khatib, F., Abu Tarboush, N., Abu-Yaghi, N., Alazzam, M., Al-Ani, A., & Mafrachi, B. (2021). Evaluating Awareness and Practices Towards Diabetes and Diabetic Retinopathy in Adult Patients Attending the Eye Clinic in a Tertiary Academic Hospital in Jordan. Clinical ophthalmology (Auckland, N.Z.), 151309-1316. https://doi.org/10.2147/OPTH.S299711
Khatib, Faisal, et al. "Evaluating Awareness and Practices Towards Diabetes and Diabetic Retinopathy in Adult Patients Attending the Eye Clinic in a Tertiary Academic Hospital in Jordan." Clinical ophthalmology (Auckland, N.Z.) vol. 15 (2021): 1309-1316. doi: https://doi.org/10.2147/OPTH.S299711
Khatib F, Abu Tarboush N, Abu-Yaghi N, Alazzam M, Al-Ani A, Mafrachi B. Evaluating Awareness and Practices Towards Diabetes and Diabetic Retinopathy in Adult Patients Attending the Eye Clinic in a Tertiary Academic Hospital in Jordan. Clin Ophthalmol. 2021 Mar 26;15:1309-1316. doi: 10.2147/OPTH.S299711. eCollection 2021. PMID: 33814898; PMCID: PMC8009538.
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Mixed NHC-thiolato complexes of palladium: understanding the formation of di-.

Dalton transactions (Cambridge, England : 2003)

Huynh HV, Ong HL, Ghatak K.
PMID: 34853842
Dalton Trans. 2021 Dec 01; doi: 10.1039/d1dt03714e. Epub 2021 Dec 01.

The preference for the formation of mono-

Cite
Huynh HV, Ong HL, Ghatak K. Mixed NHC-thiolato complexes of palladium: understanding the formation of di-. Dalton Trans. 2021;doi: 10.1039/d1dt03714e.
Huynh, H. V., Ong, H. L., & Ghatak, K. (2021). Mixed NHC-thiolato complexes of palladium: understanding the formation of di-. Dalton transactions (Cambridge, England : 2003), . https://doi.org/10.1039/d1dt03714e
Huynh, Han Vinh, et al. "Mixed NHC-thiolato complexes of palladium: understanding the formation of di-." Dalton transactions (Cambridge, England : 2003) vol. (2021). doi: https://doi.org/10.1039/d1dt03714e
Huynh HV, Ong HL, Ghatak K. Mixed NHC-thiolato complexes of palladium: understanding the formation of di-. Dalton Trans. 2021 Dec 01; doi: 10.1039/d1dt03714e. Epub 2021 Dec 01. PMID: 34853842.
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Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies.

Journal of applied microbiology

Ossai J, Khatabi B, Nybo SE, Kharel MK.
PMID: 34265147
J Appl Microbiol. 2021 Jul 15; doi: 10.1111/jam.15225. Epub 2021 Jul 15.

Actinomycetes are prolific sources of bioactive molecules. Traditional workflows including bacterial isolation, fermentation, metabolite identification and structure elucidation have resulted in high rates of natural product rediscovery in recent years. Recent advancements in multi-omics techniques have uncovered cryptic gene...

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Ossai J, Khatabi B, Nybo SE, et al. Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies. J Appl Microbiol. 2021;doi: 10.1111/jam.15225.
Ossai, J., Khatabi, B., Nybo, S. E., & Kharel, M. K. (2021). Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies. Journal of applied microbiology, . https://doi.org/10.1111/jam.15225
Ossai, Jenifer, et al. "Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies." Journal of applied microbiology vol. (2021). doi: https://doi.org/10.1111/jam.15225
Ossai J, Khatabi B, Nybo SE, Kharel MK. Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies. J Appl Microbiol. 2021 Jul 15; doi: 10.1111/jam.15225. Epub 2021 Jul 15. PMID: 34265147.
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Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production.

Journal of environmental management

Khatami K, Perez-Zabaleta M, Cetecioglu Z.
PMID: 34972045
J Environ Manage. 2021 Dec 28;305:114337. doi: 10.1016/j.jenvman.2021.114337. Epub 2021 Dec 28.

Polyhydroxyalkanoates (PHAs), as bio-based plastics, promise a transition from petroleum products to green and sustainable alternatives. However, their commercial production is yet impeded by high production costs. In this study, we assessed synthetic culture in mono and co-culture modes...

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Khatami K, Perez-Zabaleta M, Cetecioglu Z. Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production. J Environ Manage. 2021;305:114337doi: 10.1016/j.jenvman.2021.114337.
Khatami, K., Perez-Zabaleta, M., & Cetecioglu, Z. (2021). Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production. Journal of environmental management, 305114337. https://doi.org/10.1016/j.jenvman.2021.114337
Khatami, Kasra, et al. "Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production." Journal of environmental management vol. 305 (2021): 114337. doi: https://doi.org/10.1016/j.jenvman.2021.114337
Khatami K, Perez-Zabaleta M, Cetecioglu Z. Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production. J Environ Manage. 2021 Dec 28;305:114337. doi: 10.1016/j.jenvman.2021.114337. Epub 2021 Dec 28. PMID: 34972045.
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Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production.

Journal of environmental management

Khatami K, Perez-Zabaleta M, Cetecioglu Z.
PMID: 34972045
J Environ Manage. 2021 Dec 28;305:114337. doi: 10.1016/j.jenvman.2021.114337. Epub 2021 Dec 28.

Polyhydroxyalkanoates (PHAs), as bio-based plastics, promise a transition from petroleum products to green and sustainable alternatives. However, their commercial production is yet impeded by high production costs. In this study, we assessed synthetic culture in mono and co-culture modes...

Cite
Khatami K, Perez-Zabaleta M, Cetecioglu Z. Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production. J Environ Manage. 2021;305:114337doi: 10.1016/j.jenvman.2021.114337.
Khatami, K., Perez-Zabaleta, M., & Cetecioglu, Z. (2021). Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production. Journal of environmental management, 305114337. https://doi.org/10.1016/j.jenvman.2021.114337
Khatami, Kasra, et al. "Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production." Journal of environmental management vol. 305 (2021): 114337. doi: https://doi.org/10.1016/j.jenvman.2021.114337
Khatami K, Perez-Zabaleta M, Cetecioglu Z. Pure cultures for synthetic culture development: Next level municipal waste treatment for polyhydroxyalkanoates production. J Environ Manage. 2021 Dec 28;305:114337. doi: 10.1016/j.jenvman.2021.114337. Epub 2021 Dec 28. PMID: 34972045.
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