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SWOG S1400A (NCT02154490): A Phase II Study of Durvalumab for Patients With Previously Treated Stage IV or Recurrent Squamous Cell Lung Cancer (Lung-MAP Sub-study).

Clinical lung cancer

Borghaei H, Redman MW, Kelly K, Waqar SN, Robert F, Kiefer GJ, Stella PJ, Minichiello K, Gandara DR, Herbst RS, Papadimitrakopoulou VA.
PMID: 33358401
Clin Lung Cancer. 2021 May;22(3):178-186. doi: 10.1016/j.cllc.2020.10.015. Epub 2020 Nov 10.

INTRODUCTION: The objective of the Lung-MAP sub-study S1400A was to evaluate the response rate to durvalumab, an anti-programmed death-ligand 1 (PD-L1) antibody, in patients with squamous non-small-cell lung cancer (SqNSCLC).PATIENTS AND METHODS: Patients who progressed on at least 1...

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Borghaei H, Redman MW, Kelly K, et al. SWOG S1400A (NCT02154490): A Phase II Study of Durvalumab for Patients With Previously Treated Stage IV or Recurrent Squamous Cell Lung Cancer (Lung-MAP Sub-study). Clin Lung Cancer. 2020;22(3):178-186doi: 10.1016/j.cllc.2020.10.015.
Borghaei, H., Redman, M. W., Kelly, K., Waqar, S. N., Robert, F., Kiefer, G. J., Stella, P. J., Minichiello, K., Gandara, D. R., Herbst, R. S., & Papadimitrakopoulou, V. A. (2021). SWOG S1400A (NCT02154490): A Phase II Study of Durvalumab for Patients With Previously Treated Stage IV or Recurrent Squamous Cell Lung Cancer (Lung-MAP Sub-study). Clinical lung cancer, 22(3), 178-186. https://doi.org/10.1016/j.cllc.2020.10.015
Borghaei, Hossein, et al. "SWOG S1400A (NCT02154490): A Phase II Study of Durvalumab for Patients With Previously Treated Stage IV or Recurrent Squamous Cell Lung Cancer (Lung-MAP Sub-study)." Clinical lung cancer vol. 22,3 (2021): 178-186. doi: https://doi.org/10.1016/j.cllc.2020.10.015
Borghaei H, Redman MW, Kelly K, Waqar SN, Robert F, Kiefer GJ, Stella PJ, Minichiello K, Gandara DR, Herbst RS, Papadimitrakopoulou VA. SWOG S1400A (NCT02154490): A Phase II Study of Durvalumab for Patients With Previously Treated Stage IV or Recurrent Squamous Cell Lung Cancer (Lung-MAP Sub-study). Clin Lung Cancer. 2021 May;22(3):178-186. doi: 10.1016/j.cllc.2020.10.015. Epub 2020 Nov 10. PMID: 33358401.
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The Intelligent Phenotypic Plasticity Platform (IP.

Methods in molecular biology (Clifton, N.J.)

Kiefer AW, Armitano-Lago CN, Sathyan A, MacPherson R, Cohen K, Silva PL.
PMID: 34837217
Methods Mol Biol. 2022;2393:877-903. doi: 10.1007/978-1-0716-1803-5_47.

The best predictor of future injury is previous injury and this has not changed in a quarter century despite the introduction of evidence-based medicine and associated revisions to post-injury treatment and care. Nearly nine million sports-related injuries occur annually,...

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Kiefer AW, Armitano-Lago CN, Sathyan A, et al. The Intelligent Phenotypic Plasticity Platform (IP. Methods Mol Biol. 2022;2393:877-903doi: 10.1007/978-1-0716-1803-5_47.
Kiefer, A. W., Armitano-Lago, C. N., Sathyan, A., MacPherson, R., Cohen, K., & Silva, P. L. (2022). The Intelligent Phenotypic Plasticity Platform (IP. Methods in molecular biology (Clifton, N.J.), 2393877-903. https://doi.org/10.1007/978-1-0716-1803-5_47
Kiefer, Adam W, et al. "The Intelligent Phenotypic Plasticity Platform (IP." Methods in molecular biology (Clifton, N.J.) vol. 2393 (2022): 877-903. doi: https://doi.org/10.1007/978-1-0716-1803-5_47
Kiefer AW, Armitano-Lago CN, Sathyan A, MacPherson R, Cohen K, Silva PL. The Intelligent Phenotypic Plasticity Platform (IP. Methods Mol Biol. 2022;2393:877-903. doi: 10.1007/978-1-0716-1803-5_47. PMID: 34837217.
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Assessment of automated craving across substances and across cultures: stability-analysis of the Craving Automated Scale (CAS).

Journal of addictive diseases

Tan H, Nakovics H, Zeng H, Copello A, Akhtar S, Lee AM, Kiefer F, Vollstädt-Klein S.
PMID: 34967698
J Addict Dis. 2021 Dec 30;1-10. doi: 10.1080/10550887.2021.2015053. Epub 2021 Dec 30.

BACKGROUND: The transition from hedonic to compulsive use in Substance Use Disorders (SUD) is a critical point in SUD progression and hence relevant for assessment and treatment. To measure the habitual patterns of substance consumption, the Craving Automated Scales...

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Tan H, Nakovics H, Zeng H, et al. Assessment of automated craving across substances and across cultures: stability-analysis of the Craving Automated Scale (CAS). J Addict Dis. 2021;1-10doi: 10.1080/10550887.2021.2015053.
Tan, H., Nakovics, H., Zeng, H., Copello, A., Akhtar, S., Lee, A. M., Kiefer, F., & Vollstädt-Klein, S. (2021). Assessment of automated craving across substances and across cultures: stability-analysis of the Craving Automated Scale (CAS). Journal of addictive diseases, 1-10. https://doi.org/10.1080/10550887.2021.2015053
Tan, H, et al. "Assessment of automated craving across substances and across cultures: stability-analysis of the Craving Automated Scale (CAS)." Journal of addictive diseases vol. (2021): 1-10. doi: https://doi.org/10.1080/10550887.2021.2015053
Tan H, Nakovics H, Zeng H, Copello A, Akhtar S, Lee AM, Kiefer F, Vollstädt-Klein S. Assessment of automated craving across substances and across cultures: stability-analysis of the Craving Automated Scale (CAS). J Addict Dis. 2021 Dec 30;1-10. doi: 10.1080/10550887.2021.2015053. Epub 2021 Dec 30. PMID: 34967698.
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Increased network centrality of the anterior insula in early abstinence from alcohol.

Addiction biology

Bordier C, Weil G, Bach P, Scuppa G, Nicolini C, Forcellini G, Pérez-Ramirez U, Moratal D, Canals S, Hoffmann S, Hermann D, Vollstädt-Klein S, Kiefer F, Kirsch P, Sommer WH, Bifone A.
PMID: 34467604
Addict Biol. 2021 Aug 31;e13096. doi: 10.1111/adb.13096. Epub 2021 Aug 31.

Abnormal resting-state functional connectivity, as measured by functional magnetic resonance imaging (MRI), has been reported in alcohol use disorders (AUD), but findings are so far inconsistent. Here, we exploited recent developments in graph-theoretical analyses, enabling improved resolution and fine-grained...

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Bordier C, Weil G, Bach P, et al. Increased network centrality of the anterior insula in early abstinence from alcohol. Addict Biol. 2021;e13096doi: 10.1111/adb.13096.
Bordier, C., Weil, G., Bach, P., Scuppa, G., Nicolini, C., Forcellini, G., Pérez-Ramirez, U., Moratal, D., Canals, S., Hoffmann, S., Hermann, D., Vollstädt-Klein, S., Kiefer, F., Kirsch, P., Sommer, W. H., & Bifone, A. (2021). Increased network centrality of the anterior insula in early abstinence from alcohol. Addiction biology, e13096. https://doi.org/10.1111/adb.13096
Bordier, Cecile, et al. "Increased network centrality of the anterior insula in early abstinence from alcohol." Addiction biology vol. (2021): e13096. doi: https://doi.org/10.1111/adb.13096
Bordier C, Weil G, Bach P, Scuppa G, Nicolini C, Forcellini G, Pérez-Ramirez U, Moratal D, Canals S, Hoffmann S, Hermann D, Vollstädt-Klein S, Kiefer F, Kirsch P, Sommer WH, Bifone A. Increased network centrality of the anterior insula in early abstinence from alcohol. Addict Biol. 2021 Aug 31;e13096. doi: 10.1111/adb.13096. Epub 2021 Aug 31. PMID: 34467604.
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Predicting alcohol dependence from multi-site brain structural measures.

Human brain mapping

Hahn S, Mackey S, Cousijn J, Foxe JJ, Heinz A, Hester R, Hutchinson K, Kiefer F, Korucuoglu O, Lett T, Li CR, London E, Lorenzetti V, Maartje L, Momenan R, Orr C, Paulus M, Schmaal L, Sinha R, Sjoerds Z, Stein DJ, Stein E, van Holst RJ, Veltman D, Walter H, Wiers RW, Yucel M, Thompson PM, Conrod P, Allgaier N, Garavan H.
PMID: 33064342
Hum Brain Mapp. 2022 Jan;43(1):555-565. doi: 10.1002/hbm.25248. Epub 2020 Oct 16.

To identify neuroimaging biomarkers of alcohol dependence (AD) from structural magnetic resonance imaging, it may be useful to develop classification models that are explicitly generalizable to unseen sites and populations. This problem was explored in a mega-analysis of previously...

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Hahn S, Mackey S, Cousijn J, et al. Predicting alcohol dependence from multi-site brain structural measures. Hum Brain Mapp. 2020;43(1):555-565doi: 10.1002/hbm.25248.
Hahn, S., Mackey, S., Cousijn, J., Foxe, J. J., Heinz, A., Hester, R., Hutchinson, K., Kiefer, F., Korucuoglu, O., Lett, T., Li, C. R., London, E., Lorenzetti, V., Maartje, L., Momenan, R., Orr, C., Paulus, M., Schmaal, L., Sinha, R., Sjoerds, Z., Stein, D. J., Stein, E., van Holst, R. J., Veltman, D., Walter, H., Wiers, R. W., Yucel, M., Thompson, P. M., Conrod, P., Allgaier, N., & Garavan, H. (2022). Predicting alcohol dependence from multi-site brain structural measures. Human brain mapping, 43(1), 555-565. https://doi.org/10.1002/hbm.25248
Hahn, Sage, et al. "Predicting alcohol dependence from multi-site brain structural measures." Human brain mapping vol. 43,1 (2022): 555-565. doi: https://doi.org/10.1002/hbm.25248
Hahn S, Mackey S, Cousijn J, Foxe JJ, Heinz A, Hester R, Hutchinson K, Kiefer F, Korucuoglu O, Lett T, Li CR, London E, Lorenzetti V, Maartje L, Momenan R, Orr C, Paulus M, Schmaal L, Sinha R, Sjoerds Z, Stein DJ, Stein E, van Holst RJ, Veltman D, Walter H, Wiers RW, Yucel M, Thompson PM, Conrod P, Allgaier N, Garavan H. Predicting alcohol dependence from multi-site brain structural measures. Hum Brain Mapp. 2022 Jan;43(1):555-565. doi: 10.1002/hbm.25248. Epub 2020 Oct 16. PMID: 33064342; PMCID: PMC8675424.
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Lower-Third SLOE Rankings Impede, But Do Not Prevent, A Match in Emergency Medicine Residency Training.

Journal of medical education and curricular development

Hansroth JA, Davis KH, Quedado KD, Davis SM, Kiefer AS, Shaver EB, Kiefer CS, Cottrell S, Ferrari ND.
PMID: 33415307
J Med Educ Curric Dev. 2020 Dec 17;7:2382120520980487. doi: 10.1177/2382120520980487. eCollection 2020.

OBJECTIVE: Emergency medicine program directors (PD) value the standardized letter of evaluation (SLOE) as the most important aspect of a residency application when making both invitation and ranking decisions. This study aims to determine whether the presence of any...

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Hansroth JA, Davis KH, Quedado KD, et al. Lower-Third SLOE Rankings Impede, But Do Not Prevent, A Match in Emergency Medicine Residency Training. J Med Educ Curric Dev. 2020;7:2382120520980487doi: 10.1177/2382120520980487.
Hansroth, J. A., Davis, K. H., Quedado, K. D., Davis, S. M., Kiefer, A. S., Shaver, E. B., Kiefer, C. S., Cottrell, S., & Ferrari, N. D. (2020). Lower-Third SLOE Rankings Impede, But Do Not Prevent, A Match in Emergency Medicine Residency Training. Journal of medical education and curricular development, 72382120520980487. https://doi.org/10.1177/2382120520980487
Hansroth, Joseph A, et al. "Lower-Third SLOE Rankings Impede, But Do Not Prevent, A Match in Emergency Medicine Residency Training." Journal of medical education and curricular development vol. 7 (2020): 2382120520980487. doi: https://doi.org/10.1177/2382120520980487
Hansroth JA, Davis KH, Quedado KD, Davis SM, Kiefer AS, Shaver EB, Kiefer CS, Cottrell S, Ferrari ND. Lower-Third SLOE Rankings Impede, But Do Not Prevent, A Match in Emergency Medicine Residency Training. J Med Educ Curric Dev. 2020 Dec 17;7:2382120520980487. doi: 10.1177/2382120520980487. eCollection 2020. PMID: 33415307; PMCID: PMC7750759.
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Controlling Light-Induced Proton Transfer from the GFP Chromophore.

Chemphyschem : a European journal of chemical physics and physical chemistry

Langeland J, Persen NW, Gruber E, Kiefer HV, Kabylda AM, Bochenkova AV, Andersen LH.
PMID: 33949783
Chemphyschem. 2021 May 05;22(9):807. doi: 10.1002/cphc.202100281.

The front cover artwork is provided by the groups of Assoc. Prof. Anastasia V. Bochenkova (Lomonosov Moscow State University) and Prof. Lars H. Andersen (Aarhus University). The image shows the quantum nature of wavelength-dependent excited-state proton transfer in gas-phase...

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Langeland J, Persen NW, Gruber E, et al. Controlling Light-Induced Proton Transfer from the GFP Chromophore. Chemphyschem. 2021;22(9):807doi: 10.1002/cphc.202100281.
Langeland, J., Persen, N. W., Gruber, E., Kiefer, H. V., Kabylda, A. M., Bochenkova, A. V., & Andersen, L. H. (2021). Controlling Light-Induced Proton Transfer from the GFP Chromophore. Chemphyschem : a European journal of chemical physics and physical chemistry, 22(9), 807. https://doi.org/10.1002/cphc.202100281
Langeland, Jeppe, et al. "Controlling Light-Induced Proton Transfer from the GFP Chromophore." Chemphyschem : a European journal of chemical physics and physical chemistry vol. 22,9 (2021): 807. doi: https://doi.org/10.1002/cphc.202100281
Langeland J, Persen NW, Gruber E, Kiefer HV, Kabylda AM, Bochenkova AV, Andersen LH. Controlling Light-Induced Proton Transfer from the GFP Chromophore. Chemphyschem. 2021 May 05;22(9):807. doi: 10.1002/cphc.202100281. PMID: 33949783.
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Cueing Changes in Peak Vertical Ground Reaction Force to Improve Coordination Dynamics in Walking.

Journal of motor behavior

Armitano-Lago C, Pietrosimone B, Evans-Pickett A, Davis-Wilson H, Franz JR, Blackburn T, Kiefer AW.
PMID: 34148523
J Mot Behav. 2022;54(1):125-134. doi: 10.1080/00222895.2021.1929810. Epub 2021 Jun 20.

AbstractsBiofeedback has been effectively implemented to improve the mediation and distribution of joint loads during gait, however, the inability to effectively coordinate lower limb movement by altering loading patterns may increase pathological stress and risk of injury and deleterious...

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Armitano-Lago C, Pietrosimone B, Evans-Pickett A, et al. Cueing Changes in Peak Vertical Ground Reaction Force to Improve Coordination Dynamics in Walking. J Mot Behav. 2021;54(1):125-134doi: 10.1080/00222895.2021.1929810.
Armitano-Lago, C., Pietrosimone, B., Evans-Pickett, A., Davis-Wilson, H., Franz, J. R., Blackburn, T., & Kiefer, A. W. (2022). Cueing Changes in Peak Vertical Ground Reaction Force to Improve Coordination Dynamics in Walking. Journal of motor behavior, 54(1), 125-134. https://doi.org/10.1080/00222895.2021.1929810
Armitano-Lago, Cortney, et al. "Cueing Changes in Peak Vertical Ground Reaction Force to Improve Coordination Dynamics in Walking." Journal of motor behavior vol. 54,1 (2022): 125-134. doi: https://doi.org/10.1080/00222895.2021.1929810
Armitano-Lago C, Pietrosimone B, Evans-Pickett A, Davis-Wilson H, Franz JR, Blackburn T, Kiefer AW. Cueing Changes in Peak Vertical Ground Reaction Force to Improve Coordination Dynamics in Walking. J Mot Behav. 2022;54(1):125-134. doi: 10.1080/00222895.2021.1929810. Epub 2021 Jun 20. PMID: 34148523.
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Characterization and quantification of alcohol-related polyneuropathy by magnetic resonance neurography.

European journal of neurology

Rother C, Bumb JM, Weiler M, Brault A, Sam G, Hayes JM, Pietsch A, Karimian-Jazi K, Jende JME, Heiland S, Kiefer F, Bendszus M, Kollmer J.
PMID: 34564924
Eur J Neurol. 2022 Feb;29(2):573-582. doi: 10.1111/ene.15127. Epub 2021 Oct 11.

BACKGROUND: We characterized and quantified peripheral nerve damage in alcohol-dependent patients (ADP) by magnetic resonance neurography (MRN) in correlation with clinical and electrophysiologic findings.METHODS: Thirty-one adult patients with a history of excessive alcohol consumption and age-/sex-matched healthy controls were...

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Rother C, Bumb JM, Weiler M, et al. Characterization and quantification of alcohol-related polyneuropathy by magnetic resonance neurography. Eur J Neurol. 2021;29(2):573-582doi: 10.1111/ene.15127.
Rother, C., Bumb, J. M., Weiler, M., Brault, A., Sam, G., Hayes, J. M., Pietsch, A., Karimian-Jazi, K., Jende, J. M. E., Heiland, S., Kiefer, F., Bendszus, M., & Kollmer, J. (2022). Characterization and quantification of alcohol-related polyneuropathy by magnetic resonance neurography. European journal of neurology, 29(2), 573-582. https://doi.org/10.1111/ene.15127
Rother, Christian, et al. "Characterization and quantification of alcohol-related polyneuropathy by magnetic resonance neurography." European journal of neurology vol. 29,2 (2022): 573-582. doi: https://doi.org/10.1111/ene.15127
Rother C, Bumb JM, Weiler M, Brault A, Sam G, Hayes JM, Pietsch A, Karimian-Jazi K, Jende JME, Heiland S, Kiefer F, Bendszus M, Kollmer J. Characterization and quantification of alcohol-related polyneuropathy by magnetic resonance neurography. Eur J Neurol. 2022 Feb;29(2):573-582. doi: 10.1111/ene.15127. Epub 2021 Oct 11. PMID: 34564924.
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Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures.

iScience

Kirschnick N, Drees D, Redder E, Erapaneedi R, Pereira da Graca A, Schäfers M, Jiang X, Kiefer F.
PMID: 34151237
iScience. 2021 May 26;24(6):102650. doi: 10.1016/j.isci.2021.102650. eCollection 2021 Jun 25.

Light sheet fluorescence microscopy (LSFM) of large tissue samples does not require mechanical sectioning and allows efficient visualization of spatially complex or rare structures. Therefore, LSFM has become invaluable in developmental and biomedical research. Because sample size may limit...

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Kirschnick N, Drees D, Redder E, et al. Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures. iScience. 2021;24(6):102650doi: 10.1016/j.isci.2021.102650.
Kirschnick, N., Drees, D., Redder, E., Erapaneedi, R., Pereira da Graca, A., Schäfers, M., Jiang, X., & Kiefer, F. (2021). Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures. iScience, 24(6), 102650. https://doi.org/10.1016/j.isci.2021.102650
Kirschnick, Nils, et al. "Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures." iScience vol. 24,6 (2021): 102650. doi: https://doi.org/10.1016/j.isci.2021.102650
Kirschnick N, Drees D, Redder E, Erapaneedi R, Pereira da Graca A, Schäfers M, Jiang X, Kiefer F. Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures. iScience. 2021 May 26;24(6):102650. doi: 10.1016/j.isci.2021.102650. eCollection 2021 Jun 25. PMID: 34151237; PMCID: PMC8192726.
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Two families of exocomets in the β Pictoris system.

Nature

Kiefer F, des Etangs AL, Boissier J, Vidal-Madjar A, Beust H, Lagrange AM, Hébrard G, Ferlet R.
PMID: 25341784
Nature. 2014 Oct 23;514(7523):462-4. doi: 10.1038/nature13849.

The young planetary system surrounding the star β Pictoris harbours active minor bodies. These asteroids and comets produce a large amount of dust and gas through collisions and evaporation, as happened early in the history of our Solar System....

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Kiefer F, des Etangs AL, Boissier J, et al. Two families of exocomets in the β Pictoris system. Nature. 2014;514(7523):462-4doi: 10.1038/nature13849.
Kiefer, F., des Etangs, A. L., Boissier, J., Vidal-Madjar, A., Beust, H., Lagrange, A. M., Hébrard, G., & Ferlet, R. (2014). Two families of exocomets in the β Pictoris system. Nature, 514(7523), 462-4. https://doi.org/10.1038/nature13849
Kiefer, F, et al. "Two families of exocomets in the β Pictoris system." Nature vol. 514,7523 (2014): 462-4. doi: https://doi.org/10.1038/nature13849
Kiefer F, des Etangs AL, Boissier J, Vidal-Madjar A, Beust H, Lagrange AM, Hébrard G, Ferlet R. Two families of exocomets in the β Pictoris system. Nature. 2014 Oct 23;514(7523):462-4. doi: 10.1038/nature13849. PMID: 25341784.
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Common and distinct neural connectivity in attention-deficit/hyperactivity disorder and alcohol use disorder studied using resting-state functional magnetic resonance imaging.

Alcoholism, clinical and experimental research

Farré-Colomés À, Gerhardt S, Luderer M, Sobanski E, Kiefer F, Vollstädt-Klein S.
PMID: 33690916
Alcohol Clin Exp Res. 2021 May;45(5):948-960. doi: 10.1111/acer.14593. Epub 2021 Apr 02.

BACKGROUND: A link between attention-deficit/hyperactivity disorder (ADHD) and alcohol use disorder (AUD) has been widely demonstrated. In this study, we used neuroimaging to investigate the connectivity traits that may contribute to the comorbidity of these disorders.METHODS: The study included...

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Farré-Colomés À, Gerhardt S, Luderer M, et al. Common and distinct neural connectivity in attention-deficit/hyperactivity disorder and alcohol use disorder studied using resting-state functional magnetic resonance imaging. Alcohol Clin Exp Res. 2021;45(5):948-960doi: 10.1111/acer.14593.
Farré-Colomés, �. �., Gerhardt, S., Luderer, M., Sobanski, E., Kiefer, F., & Vollstädt-Klein, S. (2021). Common and distinct neural connectivity in attention-deficit/hyperactivity disorder and alcohol use disorder studied using resting-state functional magnetic resonance imaging. Alcoholism, clinical and experimental research, 45(5), 948-960. https://doi.org/10.1111/acer.14593
Farré-Colomés, Àlvar, et al. "Common and distinct neural connectivity in attention-deficit/hyperactivity disorder and alcohol use disorder studied using resting-state functional magnetic resonance imaging." Alcoholism, clinical and experimental research vol. 45,5 (2021): 948-960. doi: https://doi.org/10.1111/acer.14593
Farré-Colomés À, Gerhardt S, Luderer M, Sobanski E, Kiefer F, Vollstädt-Klein S. Common and distinct neural connectivity in attention-deficit/hyperactivity disorder and alcohol use disorder studied using resting-state functional magnetic resonance imaging. Alcohol Clin Exp Res. 2021 May;45(5):948-960. doi: 10.1111/acer.14593. Epub 2021 Apr 02. PMID: 33690916.
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