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Showing 13 to 24 of 264 entries
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Correction to 'Migration in the Anthropocene: how collective navigation, environmental system and taxonomy shape the vulnerability of migratory species'.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Hardesty-Moore M, Deinet S, Freeman R, Titcomb GC, Dillon EM, Stears K, Klope M, Bui A, Orr D, Young HS, Kuile AM, Hughey LF, McCauley DJ.
PMID: 29735744
Philos Trans R Soc Lond B Biol Sci. 2018 Jun 19;373(1749). doi: 10.1098/rstb.2018.0210.

No abstract available.

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.

Cancer cell

Kleppe M, Koche R, Zou L, van Galen P, Hill CE, Dong L, De Groote S, Papalexi E, Hanasoge Somasundara AV, Cordner K, Keller M, Farnoud N, Medina J, McGovern E, Reyes J, Roberts J, Witkin M, Rapaport F, Teruya-Feldstein J, Qi J, Rampal R, Bernstein BE, Bradner JE, Levine RL.
PMID: 29634952
Cancer Cell. 2018 Apr 09;33(4):785-787. doi: 10.1016/j.ccell.2018.03.024.

No abstract available.

DNA and RNA Extraction and Quantitative Real-Time PCR-Based Assays for Biogas Biocenoses in an Interlaboratory Comparison.

Bioengineering (Basel, Switzerland)

Lebuhn M, Derenkó J, Rademacher A, Helbig S, Munk B, Pechtl A, Stolze Y, Prowe S, Schwarz WH, Schlüter A, Liebl W, Klocke M.
PMID: 28952569
Bioengineering (Basel). 2016 Jan 13;3(1). doi: 10.3390/bioengineering3010007.

Five institutional partners participated in an interlaboratory comparison of nucleic acid extraction, RNA preservation and quantitative Real-Time PCR (qPCR) based assays for biogas biocenoses derived from different grass silage digesting laboratory and pilot scale fermenters. A kit format DNA...

International journal of systematic and evolutionary microbiology

Hahnke S, Langer T, Klocke M.
PMID: 29458500
Int J Syst Evol Microbiol. 2018 Mar;68(3):824-828. doi: 10.1099/ijsem.0.002591.

A novel strictly anaerobic bacterium, designated strain BA2-13

Harnessing "A Billion Years of Experimentation": The Ongoing Exploration and Exploitation of CRISPR-Cas Immune Systems.

The CRISPR journal

Klompe SE, Sternberg SH.
PMID: 31021200
CRISPR J. 2018 Apr;1(2):141-158. doi: 10.1089/crispr.2018.0012.

The famed physicist-turned-biologist, Max Delbrück, once remarked that, for physicists, "the field of bacterial viruses is a fine playground for serious children who ask ambitious questions." Early discoveries in that playground helped establish molecular genetics, and half a century...

Impact of Risk Adjustment Using Clinical vs Administrative Data on Hospital Sepsis Mortality Comparisons.

Open forum infectious diseases

Rhee C, Li Z, Wang R, Song Y, Kadri SS, Septimus EJ, Chen HC, Fram D, Jin R, Poland R, Sands K, Klompas M.
PMID: 32617377
Open Forum Infect Dis. 2020 Jun 25;7(6):ofaa213. doi: 10.1093/ofid/ofaa213. eCollection 2020 Jun.

BACKGROUND: A reliable risk-adjusted sepsis outcome measure could complement current national process metrics by identifying outlier hospitals and catalyzing additional improvements in care. However, it is unclear whether integrating clinical data into risk adjustment models identifies similar high- and...

Risk Adjustment for Sepsis Mortality to Facilitate Hospital Comparisons Using Centers for Disease Control and Prevention's Adult Sepsis Event Criteria and Routine Electronic Clinical Data.

Critical care explorations

Rhee C, Wang R, Song Y, Zhang Z, Kadri SS, Septimus EJ, Fram D, Jin R, Poland RE, Hickok J, Sands K, Klompas M.
PMID: 32166230
Crit Care Explor. 2019 Oct 14;1(10):e0049. doi: 10.1097/CCE.0000000000000049. eCollection 2019 Oct.

Variability in hospital-level sepsis mortality rates may be due to differences in case mix, quality of care, or diagnosis and coding practices. Centers for Disease Control and Prevention's Adult Sepsis Event definition could facilitate objective comparisons of sepsis mortality...

Structure Formation in Class I and Class II Hydrophobins at the Air-Water Interface under Multiple Compression/Expansion Cycles.

ChemistryOpen

Kordts M, Kampe M, Kerth A, Hinderberger D.
PMID: 30524926
ChemistryOpen. 2018 Nov 21;7(12):1005-1013. doi: 10.1002/open.201800176. eCollection 2018 Dec.

Hydrophobins are small amphiphilic fungal proteins empirically divided into two classes. We investigated the self-assembled structures of class I SC3 from

Exploring the catalytic cascade of cembranoid biosynthesis by combination of genetic engineering and molecular simulations.

Computational and structural biotechnology journal

Schrepfer P, Ugur I, Klumpe S, Loll B, Kaila VRI, Brück T.
PMID: 32695274
Comput Struct Biotechnol J. 2020 Jun 25;18:1819-1829. doi: 10.1016/j.csbj.2020.06.030. eCollection 2020.

While chemical steps involved in bioactive cembranoid biosynthesis have been examined, the corresponding enzymatic mechanisms leading to their formation remain elusive. In the tobacco plant,

Improvement of electrical synchrony in cardiac resynchronization therapy using dynamic atrioventricular delay programming and multipoint pacing.

Pacing and clinical electrophysiology : PACE

Schiedat F, Mijic D, Karosiene Z, Bogossian H, Zarse M, Lemke B, Hanefeld C, Mügge A, Kloppe A.
PMID: 34586643
Pacing Clin Electrophysiol. 2021 Dec;44(12):1963-1971. doi: 10.1111/pace.14372. Epub 2021 Oct 21.

BACKGROUND: Optimization of cardiac resynchronization therapy (CRT) is often time-consuming and therefore underused in a clinical setting. Novel device-based algorithms aiming to simplify optimization include a dynamic atrioventricular delay (AVD) algorithm (SyncAV, Abbott) and multipoint pacing (MPP, Abbott). This...

The Risk of SARS-CoV-2 Transmission from Patients with Undiagnosed Covid-19 to Roommates in a Large Academic Medical Center.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Karan A, Klompas M, Tucker R, Baker M, Vaidya V, Rhee C.
PMID: 34145449
Clin Infect Dis. 2021 Jun 18; doi: 10.1093/cid/ciab564. Epub 2021 Jun 18.

We assessed SARS-CoV-2 transmission between patients in shared rooms in an academic hospital between September 2020-April 2021. 11,290 patients were admitted to shared rooms, of whom 25 tested positive. Among 31 exposed roommates, 12 (39%) tested positive within 14...

Impact of an Electronic Medical Record Best Practice Alert on Expedited Partner Therapy for Chlamydia Infection and Reinfection.

Open forum infectious diseases

Willis SJ, Elder H, Cocoros NM, Callahan M, Hsu KK, Klompas M.
PMID: 35024371
Open Forum Infect Dis. 2021 Nov 16;9(1):ofab574. doi: 10.1093/ofid/ofab574. eCollection 2022 Jan.

BACKGROUND: Atrius Health implemented a best practice alert (BPA) to encourage clinicians to provide expedited partner therapy (EPT) in October 2014. We assessed (1) the impact of the BPA on EPT provision and chlamydial reinfection and (2) the impact...

Showing 13 to 24 of 264 entries