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Incidence Estimates of Perinatal Arterial Ischemic Stroke in Preterm- and Term-Born Infants: A National Capture-Recapture Calculation Corrected Surveillance Study.

Neonatology

Sorg AL, von Kries R, Klemme M, Gerstl L, Felderhoff-Müser U, Dzietko M.
PMID: 33794541
Neonatology. 2021 Apr 01;1-7. doi: 10.1159/000514922. Epub 2021 Apr 01.

INTRODUCTION: Data on valid incidence estimates of perinatal arterial ischemic stroke (PAIS) are scarce. This analysis aims to determine incidence of PAIS in term- and preterm-born infants and to investigate clinical differences related to prematurity.METHODS: This surveillance study (2015-2017)...

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Sorg AL, von Kries R, Klemme M, et al. Incidence Estimates of Perinatal Arterial Ischemic Stroke in Preterm- and Term-Born Infants: A National Capture-Recapture Calculation Corrected Surveillance Study. Neonatology. 2021;1-7doi: 10.1159/000514922.
Sorg, A. L., von Kries, R., Klemme, M., Gerstl, L., Felderhoff-Müser, U., & Dzietko, M. (2021). Incidence Estimates of Perinatal Arterial Ischemic Stroke in Preterm- and Term-Born Infants: A National Capture-Recapture Calculation Corrected Surveillance Study. Neonatology, 1-7. https://doi.org/10.1159/000514922
Sorg, Anna-Lisa, et al. "Incidence Estimates of Perinatal Arterial Ischemic Stroke in Preterm- and Term-Born Infants: A National Capture-Recapture Calculation Corrected Surveillance Study." Neonatology vol. (2021): 1-7. doi: https://doi.org/10.1159/000514922
Sorg AL, von Kries R, Klemme M, Gerstl L, Felderhoff-Müser U, Dzietko M. Incidence Estimates of Perinatal Arterial Ischemic Stroke in Preterm- and Term-Born Infants: A National Capture-Recapture Calculation Corrected Surveillance Study. Neonatology. 2021 Apr 01;1-7. doi: 10.1159/000514922. Epub 2021 Apr 01. PMID: 33794541.
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Prevalence and Clinical Characteristics of Patients With Sepsis Discharge Diagnosis Codes and Short Lengths of Stay in U.S. Hospitals.

Critical care explorations

Kuye I, Anand V, Klompas M, Chan C, Kadri SS, Rhee C.
PMID: 33786449
Crit Care Explor. 2021 Mar 16;3(3):e0373. doi: 10.1097/CCE.0000000000000373. eCollection 2021 Mar.

OBJECTIVES: Some patients diagnosed with sepsis have very brief hospitalizations. Understanding the prevalence and clinical characteristics of these patients may provide insight into how sepsis diagnoses are being applied as well as the breadth of illnesses encompassed by current...

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Kuye I, Anand V, Klompas M, et al. Prevalence and Clinical Characteristics of Patients With Sepsis Discharge Diagnosis Codes and Short Lengths of Stay in U.S. Hospitals. Crit Care Explor. 2021;3(3):e0373doi: 10.1097/CCE.0000000000000373.
Kuye, I., Anand, V., Klompas, M., Chan, C., Kadri, S. S., & Rhee, C. (2021). Prevalence and Clinical Characteristics of Patients With Sepsis Discharge Diagnosis Codes and Short Lengths of Stay in U.S. Hospitals. Critical care explorations, 3(3), e0373. https://doi.org/10.1097/CCE.0000000000000373
Kuye, Ifedayo, et al. "Prevalence and Clinical Characteristics of Patients With Sepsis Discharge Diagnosis Codes and Short Lengths of Stay in U.S. Hospitals." Critical care explorations vol. 3,3 (2021): e0373. doi: https://doi.org/10.1097/CCE.0000000000000373
Kuye I, Anand V, Klompas M, Chan C, Kadri SS, Rhee C. Prevalence and Clinical Characteristics of Patients With Sepsis Discharge Diagnosis Codes and Short Lengths of Stay in U.S. Hospitals. Crit Care Explor. 2021 Mar 16;3(3):e0373. doi: 10.1097/CCE.0000000000000373. eCollection 2021 Mar. PMID: 33786449; PMCID: PMC7994044.
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Generation of functional ciliated cholangiocytes from human pluripotent stem cells.

Nature communications

Ogawa M, Jiang JX, Xia S, Yang D, Ding A, Laselva O, Hernandez M, Cui C, Higuchi Y, Suemizu H, Dorrell C, Grompe M, Bear CE, Ogawa S.
PMID: 34764255
Nat Commun. 2021 Nov 11;12(1):6504. doi: 10.1038/s41467-021-26764-0.

The derivation of mature functional cholangiocytes from human pluripotent stem cells (hPSCs) provides a model for studying the pathogenesis of cholangiopathies and for developing therapies to treat them. Current differentiation protocols are not efficient and give rise to cholangiocytes...

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Ogawa M, Jiang JX, Xia S, et al. Generation of functional ciliated cholangiocytes from human pluripotent stem cells. Nat Commun. 2021;12(1):6504doi: 10.1038/s41467-021-26764-0.
Ogawa, M., Jiang, J. X., Xia, S., Yang, D., Ding, A., Laselva, O., Hernandez, M., Cui, C., Higuchi, Y., Suemizu, H., Dorrell, C., Grompe, M., Bear, C. E., & Ogawa, S. (2021). Generation of functional ciliated cholangiocytes from human pluripotent stem cells. Nature communications, 12(1), 6504. https://doi.org/10.1038/s41467-021-26764-0
Ogawa, Mina, et al. "Generation of functional ciliated cholangiocytes from human pluripotent stem cells." Nature communications vol. 12,1 (2021): 6504. doi: https://doi.org/10.1038/s41467-021-26764-0
Ogawa M, Jiang JX, Xia S, Yang D, Ding A, Laselva O, Hernandez M, Cui C, Higuchi Y, Suemizu H, Dorrell C, Grompe M, Bear CE, Ogawa S. Generation of functional ciliated cholangiocytes from human pluripotent stem cells. Nat Commun. 2021 Nov 11;12(1):6504. doi: 10.1038/s41467-021-26764-0. PMID: 34764255; PMCID: PMC8586142.
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Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals.

JAMA network open

Rhee C, Yu T, Wang R, Kadri SS, Fram D, Chen HC, Klompas M.
PMID: 34928358
JAMA Netw Open. 2021 Dec 01;4(12):e2138596. doi: 10.1001/jamanetworkopen.2021.38596.

IMPORTANCE: In October 2015, the Centers for Medicare & Medicaid Services began requiring US hospitals to report adherence to the Severe Sepsis and Septic Shock Early Management Bundle (SEP-1).OBJECTIVE: To evaluate the association of SEP-1 implementation with sepsis treatment...

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Rhee C, Yu T, Wang R, et al. Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals. JAMA Netw Open. 2021;4(12):e2138596doi: 10.1001/jamanetworkopen.2021.38596.
Rhee, C., Yu, T., Wang, R., Kadri, S. S., Fram, D., Chen, H. C., Klompas, M. (2021). Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals. JAMA network open, 4(12), e2138596. https://doi.org/10.1001/jamanetworkopen.2021.38596
Rhee, Chanu, et al. "Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals." JAMA network open vol. 4,12 (2021): e2138596. doi: https://doi.org/10.1001/jamanetworkopen.2021.38596
Rhee C, Yu T, Wang R, Kadri SS, Fram D, Chen HC, Klompas M. Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals. JAMA Netw Open. 2021 Dec 01;4(12):e2138596. doi: 10.1001/jamanetworkopen.2021.38596. PMID: 34928358; PMCID: PMC8689388.
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Long-Term Performance Comparison of Bipolar Active vs. Quadripolar Passive Fixation Leads in Cardiac Resynchronisation Therapy.

Frontiers in cardiovascular medicine

Schiedat F, Bogossian H, Schöne D, Aweimer A, Patsalis PC, Hanefeld C, Mügge A, Kloppe A.
PMID: 34881300
Front Cardiovasc Med. 2021 Nov 22;8:734666. doi: 10.3389/fcvm.2021.734666. eCollection 2021.

No abstract available.

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Schiedat F, Bogossian H, Schöne D, et al. Long-Term Performance Comparison of Bipolar Active vs. Quadripolar Passive Fixation Leads in Cardiac Resynchronisation Therapy. Front Cardiovasc Med. 2021;8:734666doi: 10.3389/fcvm.2021.734666.
Schiedat, F., Bogossian, H., Schöne, D., Aweimer, A., Patsalis, P. C., Hanefeld, C., Mügge, A., & Kloppe, A. (2021). Long-Term Performance Comparison of Bipolar Active vs. Quadripolar Passive Fixation Leads in Cardiac Resynchronisation Therapy. Frontiers in cardiovascular medicine, 8734666. https://doi.org/10.3389/fcvm.2021.734666
Schiedat, Fabian, et al. "Long-Term Performance Comparison of Bipolar Active vs. Quadripolar Passive Fixation Leads in Cardiac Resynchronisation Therapy." Frontiers in cardiovascular medicine vol. 8 (2021): 734666. doi: https://doi.org/10.3389/fcvm.2021.734666
Schiedat F, Bogossian H, Schöne D, Aweimer A, Patsalis PC, Hanefeld C, Mügge A, Kloppe A. Long-Term Performance Comparison of Bipolar Active vs. Quadripolar Passive Fixation Leads in Cardiac Resynchronisation Therapy. Front Cardiovasc Med. 2021 Nov 22;8:734666. doi: 10.3389/fcvm.2021.734666. eCollection 2021. PMID: 34881300; PMCID: PMC8645570.
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COVID-19 detection in cough, breath and speech using deep transfer learning and bottleneck features.

Computers in biology and medicine

Pahar M, Klopper M, Warren R, Niesler T.
PMID: 34954610
Comput Biol Med. 2021 Dec 17;141:105153. doi: 10.1016/j.compbiomed.2021.105153. Epub 2021 Dec 17.

We present an experimental investigation into the effectiveness of transfer learning and bottleneck feature extraction in detecting COVID-19 from audio recordings of cough, breath and speech. This type of screening is non-contact, does not require specialist medical expertise or...

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Pahar M, Klopper M, Warren R, et al. COVID-19 detection in cough, breath and speech using deep transfer learning and bottleneck features. Comput Biol Med. 2021;141:105153doi: 10.1016/j.compbiomed.2021.105153.
Pahar, M., Klopper, M., Warren, R., & Niesler, T. (2021). COVID-19 detection in cough, breath and speech using deep transfer learning and bottleneck features. Computers in biology and medicine, 141105153. https://doi.org/10.1016/j.compbiomed.2021.105153
Pahar, Madhurananda, et al. "COVID-19 detection in cough, breath and speech using deep transfer learning and bottleneck features." Computers in biology and medicine vol. 141 (2021): 105153. doi: https://doi.org/10.1016/j.compbiomed.2021.105153
Pahar M, Klopper M, Warren R, Niesler T. COVID-19 detection in cough, breath and speech using deep transfer learning and bottleneck features. Comput Biol Med. 2021 Dec 17;141:105153. doi: 10.1016/j.compbiomed.2021.105153. Epub 2021 Dec 17. PMID: 34954610; PMCID: PMC8679499.
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Current Insights Into Respiratory Virus Transmission and Potential Implications for Infection Control Programs : A Narrative Review.

Annals of internal medicine

Klompas M, Milton DK, Rhee C, Baker MA, Leekha S.
PMID: 34748374
Ann Intern Med. 2021 Nov 09; doi: 10.7326/M21-2780. Epub 2021 Nov 09.

Policies to prevent respiratory virus transmission in health care settings have traditionally divided organisms into Droplet versus Airborne categories. Droplet organisms (for example, influenza) are said to be transmitted via large respiratory secretions that rapidly fall to the ground...

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Klompas M, Milton DK, Rhee C, et al. Current Insights Into Respiratory Virus Transmission and Potential Implications for Infection Control Programs : A Narrative Review. Ann Intern Med. 2021;doi: 10.7326/M21-2780.
Klompas, M., Milton, D. K., Rhee, C., Baker, M. A., & Leekha, S. (2021). Current Insights Into Respiratory Virus Transmission and Potential Implications for Infection Control Programs : A Narrative Review. Annals of internal medicine, . https://doi.org/10.7326/M21-2780
Klompas, Michael, et al. "Current Insights Into Respiratory Virus Transmission and Potential Implications for Infection Control Programs : A Narrative Review." Annals of internal medicine vol. (2021). doi: https://doi.org/10.7326/M21-2780
Klompas M, Milton DK, Rhee C, Baker MA, Leekha S. Current Insights Into Respiratory Virus Transmission and Potential Implications for Infection Control Programs : A Narrative Review. Ann Intern Med. 2021 Nov 09; doi: 10.7326/M21-2780. Epub 2021 Nov 09. PMID: 34748374.
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Ventilator-associated pneumonia among SARS-CoV-2 acute respiratory distress syndrome patients.

Current opinion in critical care

Fumagalli J, Panigada M, Klompas M, Berra L.
PMID: 34932525
Curr Opin Crit Care. 2022 Feb 01;28(1):74-82. doi: 10.1097/MCC.0000000000000908.

PURPOSE OF REVIEW: We conducted a systematic literature review to summarize the available evidence regarding the incidence, risk factors, and clinical characteristics of ventilator-associated pneumonia (VAP) in patients undergoing mechanical ventilation because of acute respiratory distress syndrome secondary to...

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Fumagalli J, Panigada M, Klompas M, et al. Ventilator-associated pneumonia among SARS-CoV-2 acute respiratory distress syndrome patients. Curr Opin Crit Care. 2022;28(1):74-82doi: 10.1097/MCC.0000000000000908.
Fumagalli, J., Panigada, M., Klompas, M., & Berra, L. (2022). Ventilator-associated pneumonia among SARS-CoV-2 acute respiratory distress syndrome patients. Current opinion in critical care, 28(1), 74-82. https://doi.org/10.1097/MCC.0000000000000908
Fumagalli, Jacopo, et al. "Ventilator-associated pneumonia among SARS-CoV-2 acute respiratory distress syndrome patients." Current opinion in critical care vol. 28,1 (2022): 74-82. doi: https://doi.org/10.1097/MCC.0000000000000908
Fumagalli J, Panigada M, Klompas M, Berra L. Ventilator-associated pneumonia among SARS-CoV-2 acute respiratory distress syndrome patients. Curr Opin Crit Care. 2022 Feb 01;28(1):74-82. doi: 10.1097/MCC.0000000000000908. PMID: 34932525.
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Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial.

JAMA oncology

Lansu J, Bovée JVMG, Braam P, van Boven H, Flucke U, Bonenkamp JJ, Miah AB, Zaidi SH, Thway K, Bruland ØS, Baldini EH, Jebsen NL, Scholten AN, van den Ende PLA, Krol ADG, Ubbels JF, van der Hage JA, van Werkhoven E, Klomp HM, van der Graaf WTA, van Coevorden F, Schrage Y, van Houdt WJ, Haas RL.
PMID: 33180100
JAMA Oncol. 2021 Jan 01;7(1):e205865. doi: 10.1001/jamaoncol.2020.5865. Epub 2021 Jan 21.

IMPORTANCE: Currently, preoperative radiotherapy for all soft-tissue sarcomas is identical at a 50-Gy dose level, which can be associated with morbidity, particularly wound complications. The observed clinical radiosensitivity of the myxoid liposarcoma subtype might offer the possibility to reduce...

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Lansu J, Bovée JVMG, Braam P, et al. Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial. JAMA Oncol. 2021;7(1):e205865doi: 10.1001/jamaoncol.2020.5865.
Lansu, J., Bovée, J. V. M. G., Braam, P., van Boven, H., Flucke, U., Bonenkamp, J. J., Miah, A. B., Zaidi, S. H., Thway, K., Bruland, �. �. S., Baldini, E. H., Jebsen, N. L., Scholten, A. N., van den Ende, P. L. A., Krol, A. D. G., Ubbels, J. F., van der Hage, J. A., van Werkhoven, E., Klomp, H. M., van der Graaf, W. T. A., van Coevorden, F., Schrage, Y., van Houdt, W. J., & Haas, R. L. (2021). Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial. JAMA oncology, 7(1), e205865. https://doi.org/10.1001/jamaoncol.2020.5865
Lansu, Jules, et al. "Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial." JAMA oncology vol. 7,1 (2021): e205865. doi: https://doi.org/10.1001/jamaoncol.2020.5865
Lansu J, Bovée JVMG, Braam P, van Boven H, Flucke U, Bonenkamp JJ, Miah AB, Zaidi SH, Thway K, Bruland ØS, Baldini EH, Jebsen NL, Scholten AN, van den Ende PLA, Krol ADG, Ubbels JF, van der Hage JA, van Werkhoven E, Klomp HM, van der Graaf WTA, van Coevorden F, Schrage Y, van Houdt WJ, Haas RL. Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial. JAMA Oncol. 2021 Jan 01;7(1):e205865. doi: 10.1001/jamaoncol.2020.5865. Epub 2021 Jan 21. PMID: 33180100; PMCID: PMC7662477.
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Rationally designed rare earth separation by selective oxalate solubilization.

Chemical communications (Cambridge, England)

Prodius D, Klocke M, Smetana V, Alammar T, Perez Garcia M, Windus TL, Nlebedim IC, Mudring AV.
PMID: 32894275
Chem Commun (Camb). 2020 Sep 29;56(77):11386-11389. doi: 10.1039/d0cc02270e.

A simple, environmentally benign, and efficient chemical separation of rare earth oxalates (CSEREOX) within two rare earth element (REE) subgroups has been developed. The protocol allows for selective solubilization of water-insoluble oxalates of rare earth elements, and results in...

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Prodius D, Klocke M, Smetana V, et al. Rationally designed rare earth separation by selective oxalate solubilization. Chem Commun (Camb). 2020;56(77):11386-11389doi: 10.1039/d0cc02270e.
Prodius, D., Klocke, M., Smetana, V., Alammar, T., Perez Garcia, M., Windus, T. L., Nlebedim, I. C., & Mudring, A. V. (2020). Rationally designed rare earth separation by selective oxalate solubilization. Chemical communications (Cambridge, England), 56(77), 11386-11389. https://doi.org/10.1039/d0cc02270e
Prodius, Denis, et al. "Rationally designed rare earth separation by selective oxalate solubilization." Chemical communications (Cambridge, England) vol. 56,77 (2020): 11386-11389. doi: https://doi.org/10.1039/d0cc02270e
Prodius D, Klocke M, Smetana V, Alammar T, Perez Garcia M, Windus TL, Nlebedim IC, Mudring AV. Rationally designed rare earth separation by selective oxalate solubilization. Chem Commun (Camb). 2020 Sep 29;56(77):11386-11389. doi: 10.1039/d0cc02270e. PMID: 32894275.
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Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals.

JAMA network open

Rhee C, Yu T, Wang R, Kadri SS, Fram D, Chen HC, Klompas M.
PMID: 34928358
JAMA Netw Open. 2021 Dec 01;4(12):e2138596. doi: 10.1001/jamanetworkopen.2021.38596.

IMPORTANCE: In October 2015, the Centers for Medicare & Medicaid Services began requiring US hospitals to report adherence to the Severe Sepsis and Septic Shock Early Management Bundle (SEP-1).OBJECTIVE: To evaluate the association of SEP-1 implementation with sepsis treatment...

Cite
Rhee C, Yu T, Wang R, et al. Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals. JAMA Netw Open. 2021;4(12):e2138596doi: 10.1001/jamanetworkopen.2021.38596.
Rhee, C., Yu, T., Wang, R., Kadri, S. S., Fram, D., Chen, H. C., Klompas, M. (2021). Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals. JAMA network open, 4(12), e2138596. https://doi.org/10.1001/jamanetworkopen.2021.38596
Rhee, Chanu, et al. "Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals." JAMA network open vol. 4,12 (2021): e2138596. doi: https://doi.org/10.1001/jamanetworkopen.2021.38596
Rhee C, Yu T, Wang R, Kadri SS, Fram D, Chen HC, Klompas M. Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals. JAMA Netw Open. 2021 Dec 01;4(12):e2138596. doi: 10.1001/jamanetworkopen.2021.38596. PMID: 34928358.
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Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China: A Nested Case-Control Study.

Critical care medicine

Wang W, Zhu S, He Q, Wang M, Kang Y, Zhang R, Ji P, Zou K, Klompas M, Zong Z, Sun X.
PMID: 34473657
Crit Care Med. 2021 Aug 13; doi: 10.1097/CCM.0000000000005227. Epub 2021 Aug 13.

OBJECTIVES: Fluid therapy is an important component of intensive care management, however, optimal fluid management is unknown. The relationship between fluid balance and ventilator-associated events has not been well established. This study investigated the dose-response relationship between fluid balance...

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Wang W, Zhu S, He Q, et al. Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China: A Nested Case-Control Study. Crit Care Med. 2021;doi: 10.1097/CCM.0000000000005227.
Wang, W., Zhu, S., He, Q., Wang, M., Kang, Y., Zhang, R., Ji, P., Zou, K., Klompas, M., Zong, Z., & Sun, X. (2021). Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China: A Nested Case-Control Study. Critical care medicine, . https://doi.org/10.1097/CCM.0000000000005227
Wang, Wen, et al. "Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China: A Nested Case-Control Study." Critical care medicine vol. (2021). doi: https://doi.org/10.1097/CCM.0000000000005227
Wang W, Zhu S, He Q, Wang M, Kang Y, Zhang R, Ji P, Zou K, Klompas M, Zong Z, Sun X. Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China: A Nested Case-Control Study. Crit Care Med. 2021 Aug 13; doi: 10.1097/CCM.0000000000005227. Epub 2021 Aug 13. PMID: 34473657.
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