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Showing 25 to 36 of 57 entries
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Bio-Based Bisbenzoxazines with Flame Retardant Linker.

Polymers

Haubold TS, Puchot L, Adjaoud A, Verge P, Koschek K.
PMID: 34960884
Polymers (Basel). 2021 Dec 10;13(24). doi: 10.3390/polym13244330.

This work explores the strategy of incorporating a highly substituted reactive flame retardant into a benzoxazine moiety. For this purpose, a DOPO-based flame retardant received a chain extension via reaction with ethylene carbonate. It was then reacted with phloretic...

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Haubold TS, Puchot L, Adjaoud A, et al. Bio-Based Bisbenzoxazines with Flame Retardant Linker. Polymers (Basel). 2021;13(24)doi: 10.3390/polym13244330.
Haubold, T. S., Puchot, L., Adjaoud, A., Verge, P., & Koschek, K. (2021). Bio-Based Bisbenzoxazines with Flame Retardant Linker. Polymers, 13(24), . https://doi.org/10.3390/polym13244330
Haubold, Thorben Sören, et al. "Bio-Based Bisbenzoxazines with Flame Retardant Linker." Polymers vol. 13,24 (2021). doi: https://doi.org/10.3390/polym13244330
Haubold TS, Puchot L, Adjaoud A, Verge P, Koschek K. Bio-Based Bisbenzoxazines with Flame Retardant Linker. Polymers (Basel). 2021 Dec 10;13(24). doi: 10.3390/polym13244330. PMID: 34960884; PMCID: PMC8707438.
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Secondary Prevention of Dementia: Combining Risk Factors and Scalable Screening Technology.

Frontiers in neurology

Ojakäär T, Koychev I.
PMID: 34867762
Front Neurol. 2021 Nov 15;12:772836. doi: 10.3389/fneur.2021.772836. eCollection 2021.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is the most common cause of dementia. Over a third of dementia cases are estimated to be due to potentially modifiable risk factors, thus offering opportunities for both identification of...

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Ojakäär T, Koychev I. Secondary Prevention of Dementia: Combining Risk Factors and Scalable Screening Technology. Front Neurol. 2021;12:772836doi: 10.3389/fneur.2021.772836.
Ojakäär, T., & Koychev, I. (2021). Secondary Prevention of Dementia: Combining Risk Factors and Scalable Screening Technology. Frontiers in neurology, 12772836. https://doi.org/10.3389/fneur.2021.772836
Ojakäär, Triin, and Koychev, Ivan. "Secondary Prevention of Dementia: Combining Risk Factors and Scalable Screening Technology." Frontiers in neurology vol. 12 (2021): 772836. doi: https://doi.org/10.3389/fneur.2021.772836
Ojakäär T, Koychev I. Secondary Prevention of Dementia: Combining Risk Factors and Scalable Screening Technology. Front Neurol. 2021 Nov 15;12:772836. doi: 10.3389/fneur.2021.772836. eCollection 2021. PMID: 34867762; PMCID: PMC8634660.
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Towards FAIR nanosafety data.

Nature nanotechnology

Jeliazkova N, Apostolova MD, Andreoli C, Barone F, Barrick A, Battistelli C, Bossa C, Botea-Petcu A, Châtel A, De Angelis I, Dusinska M, El Yamani N, Gheorghe D, Giusti A, Gómez-Fernández P, Grafström R, Gromelski M, Jacobsen NR, Jeliazkov V, Jensen KA, Kochev N, Kohonen P, Manier N, Mariussen E, Mech A, Navas JM, Paskaleva V, Precupas A, Puzyn T, Rasmussen K, Ritchie P, Llopis IR, Rundén-Pran E, Sandu R, Shandilya N, Tanasescu S, Haase A, Nymark P.
PMID: 34017099
Nat Nanotechnol. 2021 Jun;16(6):644-654. doi: 10.1038/s41565-021-00911-6. Epub 2021 May 20.

Nanotechnology is a key enabling technology with billions of euros in global investment from public funding, which include large collaborative projects that have investigated environmental and health safety aspects of nanomaterials, but the reuse of accumulated data is clearly...

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Jeliazkova N, Apostolova MD, Andreoli C, et al. Towards FAIR nanosafety data. Nat Nanotechnol. 2021;16(6):644-654doi: 10.1038/s41565-021-00911-6.
Jeliazkova, N., Apostolova, M. D., Andreoli, C., Barone, F., Barrick, A., Battistelli, C., Bossa, C., Botea-Petcu, A., Châtel, A., De Angelis, I., Dusinska, M., El Yamani, N., Gheorghe, D., Giusti, A., Gómez-Fernández, P., Grafström, R., Gromelski, M., Jacobsen, N. R., Jeliazkov, V., Jensen, K. A., Kochev, N., Kohonen, P., Manier, N., Mariussen, E., Mech, A., Navas, J. M., Paskaleva, V., Precupas, A., Puzyn, T., Rasmussen, K., Ritchie, P., Llopis, I. R., Rundén-Pran, E., Sandu, R., Shandilya, N., Tanasescu, S., Haase, A., & Nymark, P. (2021). Towards FAIR nanosafety data. Nature nanotechnology, 16(6), 644-654. https://doi.org/10.1038/s41565-021-00911-6
Jeliazkova, Nina, et al. "Towards FAIR nanosafety data." Nature nanotechnology vol. 16,6 (2021): 644-654. doi: https://doi.org/10.1038/s41565-021-00911-6
Jeliazkova N, Apostolova MD, Andreoli C, Barone F, Barrick A, Battistelli C, Bossa C, Botea-Petcu A, Châtel A, De Angelis I, Dusinska M, El Yamani N, Gheorghe D, Giusti A, Gómez-Fernández P, Grafström R, Gromelski M, Jacobsen NR, Jeliazkov V, Jensen KA, Kochev N, Kohonen P, Manier N, Mariussen E, Mech A, Navas JM, Paskaleva V, Precupas A, Puzyn T, Rasmussen K, Ritchie P, Llopis IR, Rundén-Pran E, Sandu R, Shandilya N, Tanasescu S, Haase A, Nymark P. Towards FAIR nanosafety data. Nat Nanotechnol. 2021 Jun;16(6):644-654. doi: 10.1038/s41565-021-00911-6. Epub 2021 May 20. PMID: 34017099.
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Properties of glucose oxidase immobilized in gel of polyvinylalcohol.

Biotechnology and bioengineering

Kozhukharova A, Kirova N, Popova Y, Batsalova K, Kunchev K.
PMID: 18584742
Biotechnol Bioeng. 1988 Jul 05;32(2):245-8. doi: 10.1002/bit.260320216.

No abstract available.

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Kozhukharova A, Kirova N, Popova Y, et al. Properties of glucose oxidase immobilized in gel of polyvinylalcohol. Biotechnol Bioeng. 1988;32(2):245-8doi: 10.1002/bit.260320216.
Kozhukharova, A., Kirova, N., Popova, Y., Batsalova, K., & Kunchev, K. (1988). Properties of glucose oxidase immobilized in gel of polyvinylalcohol. Biotechnology and bioengineering, 32(2), 245-8. https://doi.org/10.1002/bit.260320216
Kozhukharova, A, et al. "Properties of glucose oxidase immobilized in gel of polyvinylalcohol." Biotechnology and bioengineering vol. 32,2 (1988): 245-8. doi: https://doi.org/10.1002/bit.260320216
Kozhukharova A, Kirova N, Popova Y, Batsalova K, Kunchev K. Properties of glucose oxidase immobilized in gel of polyvinylalcohol. Biotechnol Bioeng. 1988 Jul 05;32(2):245-8. doi: 10.1002/bit.260320216. PMID: 18584742.
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Role of extracellular calcium and calcium stores in the intracellular calcium rise induced by diethylstilboestrol in C6 rat glioma cells.

Toxicology in vitro : an international journal published in association with BIBRA

Tas P, Ambs S, Stopper H, Koschel K, Schiffmann D.
PMID: 20650070
Toxicol In Vitro. 1995 Apr;9(2):117-21. doi: 10.1016/0887-2333(94)00203-7.

The aneuploidy-inducing carcinogenic oestrogen diethylstilboestrol (DES) causes an elevation of the cytoplasmic Ca(2+) concentration of C6 rat glioma cells. It is known that the intracellular calcium concentration is a critical factor in mitosis. DES induces mitotic disturbances resulting in...

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Tas P, Ambs S, Stopper H, et al. Role of extracellular calcium and calcium stores in the intracellular calcium rise induced by diethylstilboestrol in C6 rat glioma cells. Toxicol In Vitro. 1995;9(2):117-21doi: 10.1016/0887-2333(94)00203-7.
Tas, P., Ambs, S., Stopper, H., Koschel, K., & Schiffmann, D. (1995). Role of extracellular calcium and calcium stores in the intracellular calcium rise induced by diethylstilboestrol in C6 rat glioma cells. Toxicology in vitro : an international journal published in association with BIBRA, 9(2), 117-21. https://doi.org/10.1016/0887-2333(94)00203-7
Tas, P, et al. "Role of extracellular calcium and calcium stores in the intracellular calcium rise induced by diethylstilboestrol in C6 rat glioma cells." Toxicology in vitro : an international journal published in association with BIBRA vol. 9,2 (1995): 117-21. doi: https://doi.org/10.1016/0887-2333(94)00203-7
Tas P, Ambs S, Stopper H, Koschel K, Schiffmann D. Role of extracellular calcium and calcium stores in the intracellular calcium rise induced by diethylstilboestrol in C6 rat glioma cells. Toxicol In Vitro. 1995 Apr;9(2):117-21. doi: 10.1016/0887-2333(94)00203-7. PMID: 20650070.
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Imaging Aβ and tau in early stage Alzheimer's disease with [.

EJNMMI research

Firouzian A, Whittington A, Searle GE, Koychev I, Zamboni G, Lovestone S, Gunn RN.
PMID: 29500717
EJNMMI Res. 2018 Mar 02;8(1):19. doi: 10.1186/s13550-018-0371-y.

BACKGROUND: AD is a progressive neurodegenerative disorder that is associated with the accumulation of two different insoluble protein aggregates, Aβ plaques and hyperphosphorylated tau. This study aimed to investigate the optimal acquisition and quantification of [RESULTS: Both the SRTM...

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Firouzian A, Whittington A, Searle GE, et al. Imaging Aβ and tau in early stage Alzheimer's disease with [. EJNMMI Res. 2018;8(1):19doi: 10.1186/s13550-018-0371-y.
Firouzian, A., Whittington, A., Searle, G. E., Koychev, I., Zamboni, G., Lovestone, S., Gunn, R. N. (2018). Imaging Aβ and tau in early stage Alzheimer's disease with [. EJNMMI research, 8(1), 19. https://doi.org/10.1186/s13550-018-0371-y
Firouzian, Azadeh, et al. "Imaging Aβ and tau in early stage Alzheimer's disease with [." EJNMMI research vol. 8,1 (2018): 19. doi: https://doi.org/10.1186/s13550-018-0371-y
Firouzian A, Whittington A, Searle GE, Koychev I, Zamboni G, Lovestone S, Gunn RN. Imaging Aβ and tau in early stage Alzheimer's disease with [. EJNMMI Res. 2018 Mar 02;8(1):19. doi: 10.1186/s13550-018-0371-y. PMID: 29500717; PMCID: PMC5834417.
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Thermosetting Shape Memory Polymers and Composites Based on Polybenzoxazine Blends, Alloys and Copolymers.

Chemistry, an Asian journal

Mora P, Schäfer H, Jubsilp C, Rimdusit S, Koschek K.
PMID: 31777193
Chem Asian J. 2019 Dec 02;14(23):4129-4139. doi: 10.1002/asia.201900969. Epub 2019 Nov 28.

When dealing with smart polymers, in particular with shape memory polymers, the polymer type and composition specify the overall material properties and in particular the extent of the shape memory effect. Polybenzoxazines as a polymer with high potential for...

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Mora P, Schäfer H, Jubsilp C, et al. Thermosetting Shape Memory Polymers and Composites Based on Polybenzoxazine Blends, Alloys and Copolymers. Chem Asian J. 2019;14(23):4129-4139doi: 10.1002/asia.201900969.
Mora, P., Schäfer, H., Jubsilp, C., Rimdusit, S., & Koschek, K. (2019). Thermosetting Shape Memory Polymers and Composites Based on Polybenzoxazine Blends, Alloys and Copolymers. Chemistry, an Asian journal, 14(23), 4129-4139. https://doi.org/10.1002/asia.201900969
Mora, Phattarin, et al. "Thermosetting Shape Memory Polymers and Composites Based on Polybenzoxazine Blends, Alloys and Copolymers." Chemistry, an Asian journal vol. 14,23 (2019): 4129-4139. doi: https://doi.org/10.1002/asia.201900969
Mora P, Schäfer H, Jubsilp C, Rimdusit S, Koschek K. Thermosetting Shape Memory Polymers and Composites Based on Polybenzoxazine Blends, Alloys and Copolymers. Chem Asian J. 2019 Dec 02;14(23):4129-4139. doi: 10.1002/asia.201900969. Epub 2019 Nov 28. PMID: 31777193; PMCID: PMC6916285.
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Erratum to: ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics.

Journal of cheminformatics

Sun J, Jeliazkova N, Chupakhin V, Golib-Dzib JF, Engkvist O, Carlsson L, Wegner J, Ceulemans H, Georgiev I, Jeliazkov V, Kochev N, Ashby TJ, Chen H.
PMID: 29086166
J Cheminform. 2017 Jun 14;9(1):41. doi: 10.1186/s13321-017-0222-2.

No abstract available.

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Sun J, Jeliazkova N, Chupakhin V, et al. Erratum to: ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics. J Cheminform. 2017;9(1):41doi: 10.1186/s13321-017-0222-2.
Sun, J., Jeliazkova, N., Chupakhin, V., Golib-Dzib, J. F., Engkvist, O., Carlsson, L., Wegner, J., Ceulemans, H., Georgiev, I., Jeliazkov, V., Kochev, N., Ashby, T. J., & Chen, H. (2017). Erratum to: ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics. Journal of cheminformatics, 9(1), 41. https://doi.org/10.1186/s13321-017-0222-2
Sun, Jiangming, et al. "Erratum to: ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics." Journal of cheminformatics vol. 9,1 (2017): 41. doi: https://doi.org/10.1186/s13321-017-0222-2
Sun J, Jeliazkova N, Chupakhin V, Golib-Dzib JF, Engkvist O, Carlsson L, Wegner J, Ceulemans H, Georgiev I, Jeliazkov V, Kochev N, Ashby TJ, Chen H. Erratum to: ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics. J Cheminform. 2017 Jun 14;9(1):41. doi: 10.1186/s13321-017-0222-2. PMID: 29086166; PMCID: PMC5471272.
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Ambit-SMIRKS: a software module for reaction representation, reaction search and structure transformation.

Journal of cheminformatics

Kochev N, Avramova S, Jeliazkova N.
PMID: 30128804
J Cheminform. 2018 Aug 20;10(1):42. doi: 10.1186/s13321-018-0295-6.

Ambit-SMIRKS is an open source software, enabling structure transformation via the SMIRKS language and implemented as an extension of Ambit-SMARTS. As part of the Ambit project it builds on top of The Chemistry Development Kit (The CDK). Ambit-SMIRKS provides...

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Kochev N, Avramova S, Jeliazkova N. Ambit-SMIRKS: a software module for reaction representation, reaction search and structure transformation. J Cheminform. 2018;10(1):42doi: 10.1186/s13321-018-0295-6.
Kochev, N., Avramova, S., & Jeliazkova, N. (2018). Ambit-SMIRKS: a software module for reaction representation, reaction search and structure transformation. Journal of cheminformatics, 10(1), 42. https://doi.org/10.1186/s13321-018-0295-6
Kochev, Nikolay, et al. "Ambit-SMIRKS: a software module for reaction representation, reaction search and structure transformation." Journal of cheminformatics vol. 10,1 (2018): 42. doi: https://doi.org/10.1186/s13321-018-0295-6
Kochev N, Avramova S, Jeliazkova N. Ambit-SMIRKS: a software module for reaction representation, reaction search and structure transformation. J Cheminform. 2018 Aug 20;10(1):42. doi: 10.1186/s13321-018-0295-6. PMID: 30128804; PMCID: PMC6102164.
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Peptide-polymer ligands for a tandem WW-domain, an adaptive multivalent protein-protein interaction: lessons on the thermodynamic fitness of flexible ligands.

Beilstein journal of organic chemistry

Koschek K, Durmaz V, Krylova O, Wieczorek M, Gupta S, Richter M, Bujotzek A, Fischer C, Haag R, Freund C, Weber M, Rademann J.
PMID: 26124884
Beilstein J Org Chem. 2015 May 18;11:837-47. doi: 10.3762/bjoc.11.93. eCollection 2015.

Three polymers, poly(N-(2-hydroxypropyl)methacrylamide) (pHPMA), hyperbranched polyglycerol (hPG), and dextran were investigated as carriers for multivalent ligands targeting the adaptive tandem WW-domain of formin-binding protein (FBP21). Polymer carriers were conjugated with 3-9 copies of the proline-rich decapeptide GPPPRGPPPR-NH2 (P1). Binding...

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Koschek K, Durmaz V, Krylova O, et al. Peptide-polymer ligands for a tandem WW-domain, an adaptive multivalent protein-protein interaction: lessons on the thermodynamic fitness of flexible ligands. Beilstein J Org Chem. 2015;11:837-47doi: 10.3762/bjoc.11.93.
Koschek, K., Durmaz, V., Krylova, O., Wieczorek, M., Gupta, S., Richter, M., Bujotzek, A., Fischer, C., Haag, R., Freund, C., Weber, M., & Rademann, J. (2015). Peptide-polymer ligands for a tandem WW-domain, an adaptive multivalent protein-protein interaction: lessons on the thermodynamic fitness of flexible ligands. Beilstein journal of organic chemistry, 11837-47. https://doi.org/10.3762/bjoc.11.93
Koschek, Katharina, et al. "Peptide-polymer ligands for a tandem WW-domain, an adaptive multivalent protein-protein interaction: lessons on the thermodynamic fitness of flexible ligands." Beilstein journal of organic chemistry vol. 11 (2015): 837-47. doi: https://doi.org/10.3762/bjoc.11.93
Koschek K, Durmaz V, Krylova O, Wieczorek M, Gupta S, Richter M, Bujotzek A, Fischer C, Haag R, Freund C, Weber M, Rademann J. Peptide-polymer ligands for a tandem WW-domain, an adaptive multivalent protein-protein interaction: lessons on the thermodynamic fitness of flexible ligands. Beilstein J Org Chem. 2015 May 18;11:837-47. doi: 10.3762/bjoc.11.93. eCollection 2015. PMID: 26124884; PMCID: PMC4464424.
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ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics.

Journal of cheminformatics

Sun J, Jeliazkova N, Chupakin V, Golib-Dzib JF, Engkvist O, Carlsson L, Wegner J, Ceulemans H, Georgiev I, Jeliazkov V, Kochev N, Ashby TJ, Chen H.
PMID: 28316655
J Cheminform. 2017 Mar 07;9:17. doi: 10.1186/s13321-017-0203-5. eCollection 2017.

Chemogenomics data generally refers to the activity data of chemical compounds on an array of protein targets and represents an important source of information for building

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Sun J, Jeliazkova N, Chupakin V, et al. ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics. J Cheminform. 2017;9:17doi: 10.1186/s13321-017-0203-5.
Sun, J., Jeliazkova, N., Chupakin, V., Golib-Dzib, J. F., Engkvist, O., Carlsson, L., Wegner, J., Ceulemans, H., Georgiev, I., Jeliazkov, V., Kochev, N., Ashby, T. J., & Chen, H. (2017). ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics. Journal of cheminformatics, 917. https://doi.org/10.1186/s13321-017-0203-5
Sun, Jiangming, et al. "ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics." Journal of cheminformatics vol. 9 (2017): 17. doi: https://doi.org/10.1186/s13321-017-0203-5
Sun J, Jeliazkova N, Chupakin V, Golib-Dzib JF, Engkvist O, Carlsson L, Wegner J, Ceulemans H, Georgiev I, Jeliazkov V, Kochev N, Ashby TJ, Chen H. ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics. J Cheminform. 2017 Mar 07;9:17. doi: 10.1186/s13321-017-0203-5. eCollection 2017. PMID: 28316655; PMCID: PMC5340785.
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Renal hemangiopericytoma in 15 year old female-treated laparoscopically.

Urology case reports

Anakievski D, Kalchev K.
PMID: 32195122
Urol Case Rep. 2020 Mar 11;31:101132. doi: 10.1016/j.eucr.2020.101132. eCollection 2020 Jul.

Hemangiopericytoma (HPC) is rare in the urogenital system, most frequently occurs in the pelvis, head and neck, and meninges, it is extremely rare in the kidney. US, CT, or MRI do not show any specific sign of renal HPC...

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Anakievski D, Kalchev K. Renal hemangiopericytoma in 15 year old female-treated laparoscopically. Urol Case Rep. 2020;31:101132doi: 10.1016/j.eucr.2020.101132.
Anakievski, D., & Kalchev, K. (2020). Renal hemangiopericytoma in 15 year old female-treated laparoscopically. Urology case reports, 31101132. https://doi.org/10.1016/j.eucr.2020.101132
Anakievski, D, and Kalchev, K. "Renal hemangiopericytoma in 15 year old female-treated laparoscopically." Urology case reports vol. 31 (2020): 101132. doi: https://doi.org/10.1016/j.eucr.2020.101132
Anakievski D, Kalchev K. Renal hemangiopericytoma in 15 year old female-treated laparoscopically. Urol Case Rep. 2020 Mar 11;31:101132. doi: 10.1016/j.eucr.2020.101132. eCollection 2020 Jul. PMID: 32195122; PMCID: PMC7076144.
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Showing 25 to 36 of 57 entries