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Showing 265 to 268 of 268 entries
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First-line sorafenib sequential therapy and liver disease etiology for unresectable hepatocellular carcinoma using inverse probability weighting: A multicenter retrospective study.

Cancer medicine

Shimose S, Hiraoka A, Nakano M, Iwamoto H, Tanaka M, Tanaka T, Noguchi K, Aino H, Ogata K, Kajiwara M, Itano S, Yokokura Y, Yamaguchi T, Kawano H, Matsukuma N, Suga H, Niizeki T, Shirono T, Noda Y, Kamachi N, Okamura S, Kawaguchi T, Koga H, Torimura T.
PMID: 34693661
Cancer Med. 2021 Dec;10(23):8530-8541. doi: 10.1002/cam4.4367. Epub 2021 Oct 24.

BACKGROUND AND AIMS: Sequential therapy with molecular-targeted agents (MTAs) is considered effective for unresectable hepatocellular carcinoma (HCC) patients. This study purposed to evaluate the efficacy of sequential therapy with sorafenib (SORA) as a first-line therapy and to investigate the...

Efficient CRISPR-Cas9-Mediated Knock-In of Composite Tags in Zebrafish Using Long ssDNA as a Donor.

Frontiers in cell and developmental biology

Ranawakage DC, Okada K, Sugio K, Kawaguchi Y, Kuninobu-Bonkohara Y, Takada T, Kamachi Y.
PMID: 33681181
Front Cell Dev Biol. 2021 Feb 11;8:598634. doi: 10.3389/fcell.2020.598634. eCollection 2020.

Despite the unprecedented gene editing capability of CRISPR-Cas9-mediated targeted knock-in, the efficiency and precision of this technology still require further optimization, particularly for multicellular model organisms, such as the zebrafish (

Multimolecular-Targeted Agents for Intermediate-Stage Hepatocellular Carcinoma Influence Time to Stage Progression and Overall Survival.

Oncology

Shimose S, Iwamoto H, Tanaka M, Niizeki T, Shirono T, Kajiwara A, Noda Y, Kamachi N, Okamura S, Nakano M, Kuromatsu R, Kawaguchi T, Koga H, Torimura T.
PMID: 34518483
Oncology. 2021;99(12):756-765. doi: 10.1159/000518612. Epub 2021 Sep 08.

Background & Aims: Intermediate hepatocellular carcinoma (HCC) treatment has become complicated due to the development of various molecular-targeted agents (MTAs). We aimed to determine whether the administration of MTAs in patients with intermediate-stage HCC contributed to the prevention of...

Acute Myocardial Infarction of the Left Main Coronary Artery Presenting with Cardiogenic Shock and Pulmonary Edema during Noncardiac Surgery.

Case reports in cardiology

Takenaka S, Konishi T, Sato T, Tada A, Koizumi T, Mizuguchi Y, Kadosaka T, Motoi K, Kobayashi Y, Komoriyama H, Kato Y, Sarashina M, Omote K, Tsujinaga S, Sato T, Kamada R, Kamiya K, Iwano H, Nagai T, Orimo T, Kamachi H, Taketomi A, Anzai T.
PMID: 34430055
Case Rep Cardiol. 2021 Aug 13;2021:5460816. doi: 10.1155/2021/5460816. eCollection 2021.

Acute myocardial infarction (AMI) caused by severe stenosis of left main coronary artery (LMCA) presenting with cardiogenic shock and pulmonary edema during noncardiac surgery is uncommon, but a catastrophic event. A 77-year-old male with cholangiocarcinoma underwent hepatectomy. During the...

Showing 265 to 268 of 268 entries