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Showing 241 to 245 of 245 entries
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PET-RAFT and SAXS: High Throughput Tools to Study Compactness and Flexibility of Single-Chain Polymer Nanoparticles.

Macromolecules

Upadhya R, Murthy NS, Hoop CL, Kosuri S, Nanda V, Kohn J, Baum J, Gormley AJ.
PMID: 33814613
Macromolecules. 2019 Nov 12;52(21):8295-8304. doi: 10.1021/acs.macromol.9b01923. Epub 2019 Oct 25.

From protein science, it is well understood that ordered folding and 3D structure mainly arises from balanced and noncovalent polar and nonpolar interactions, such as hydrogen bonding. Similarly, it is understood that single-chain polymer nanoparticles (SCNPs) will also compact...

Discharge destination influences risks of readmission and complications after lumbar spine surgery in severely disabled patients.

Clinical neurology and neurosurgery

Park C, Cook CE, Garcia AN, Gottfried ON.
PMID: 34298352
Clin Neurol Neurosurg. 2021 Aug;207:106801. doi: 10.1016/j.clineuro.2021.106801. Epub 2021 Jul 07.

OBJECTIVE: For individuals with severe disability requiring spine surgery, appropriate discharge destination is a challenging and complex decision. Past studies have found associations between discharge destination and postoperative outcomes but were limited by biases in sampling characteristics. The purpose...

NMR unveils an N-terminal interaction interface on acetylated-α-synuclein monomers for recruitment to fibrils.

Proceedings of the National Academy of Sciences of the United States of America

Yang X, Wang B, Hoop CL, Williams JK, Baum J.
PMID: 33903234
Proc Natl Acad Sci U S A. 2021 May 04;118(18). doi: 10.1073/pnas.2017452118.

Amyloid fibril formation of α-synuclein (αS) is associated with multiple neurodegenerative diseases, including Parkinson's disease (PD). Growing evidence suggests that progression of PD is linked to cell-to-cell propagation of αS fibrils, which leads to seeding of endogenous intrinsically disordered...

The pink salmon genome: Uncovering the genomic consequences of a two-year life cycle.

PloS one

Christensen KA, Rondeau EB, Sakhrani D, Biagi CA, Johnson H, Joshi J, Flores AM, Leelakumari S, Moore R, Pandoh PK, Withler RE, Beacham TD, Leggatt RA, Tarpey CM, Seeb LW, Seeb JE, Jones SJM, Devlin RH, Koop BF.
PMID: 34919547
PLoS One. 2021 Dec 17;16(12):e0255752. doi: 10.1371/journal.pone.0255752. eCollection 2021.

Pink salmon (Oncorhynchus gorbuscha) adults are the smallest of the five Pacific salmon native to the western Pacific Ocean. Pink salmon are also the most abundant of these species and account for a large proportion of the commercial value...

Physician burnout and professional satisfaction in orthopedic surgeons during the COVID-19 Pandemic.

Work (Reading, Mass.)

Lazarides AL, Belay ES, Anastasio AT, Cook CE, Anakwenze OA.
PMID: 33998571
Work. 2021;69(1):15-22. doi: 10.3233/WOR-205288.

BACKGROUND: Burnout and professional satisfaction is an often an overlooked component for healthcare outcomes; the COVID-19 pandemic represents an unprecedented stressor that could contribute to higher levels of burnout.OBJECTIVES: Our primary objective was to evaluate the association of a...

Showing 241 to 245 of 245 entries