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Showing 13 to 24 of 30 entries
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Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer's type in an elderly Arab population in Wadi Ara, Israel.

Neuropsychiatric disease and treatment

Bowirrat A, Cui J, Waraska K, Friedland RP, Oscar-Berman M, Farrer LA, Korczyn A, Baldwin CT.
PMID: 18568123
Neuropsychiatr Dis Treat. 2005 Mar;1(1):73-6. doi: 10.2147/nedt.1.1.73.52302.

The angiotensin-converting enzyme (ACE), a protease involved in blood pressure regulation, has been implicated as an important candidate gene for Alzheimer's disease (AD). This study investigated whether the ACE gene insertion-deletion (ID) polymorphism is associated with risk of developing...

Tolerance to the analgesic effect of buprenorphine, butorphanol, nalbuphine, and cyclorphan, and cross-tolerance to morphine.

Journal of anesthesia

Gringauz M, Rabinowitz R, Stav A, Korczyn AD.
PMID: 14569437
J Anesth. 2001;15(4):204-9. doi: 10.1007/s005400170004.

PURPOSE: The increased use of opioids in the chronic treatment of pain, especially with oncologic patients, encourages the search for drugs with potent analgesic activity, but with minimal induced tolerance and cross-tolerance to morphine.METHODS: Four agonist-antagonist opioid derivatives (buprenorphine,...

Modeling the dementia epidemic.

CNS neuroscience & therapeutics

Treves TA, Korczyn AD.
PMID: 22070738
CNS Neurosci Ther. 2012 Feb;18(2):175-81. doi: 10.1111/j.1755-5949.2011.00242.x. Epub 2011 Mar 21.

The incidence of dementia increases steeply with age in older people, although from the tenth decade the slope may be smoother, perhaps reflecting different pathological processes in the oldest old. The prevalence depends upon interaction of age with other...

Tolerance to the mydriatic effect of buprenorphine, butorphanol, nalbuphine, and cyclorphan, and cross-tolerance to morphine in mice.

Journal of anesthesia

Kaadan M, Stav A, Rabinowitz R, Shavit S, Korczyn AD.
PMID: 23568116
J Anesth. 1994 Sep;8(3):297-300. doi: 10.1007/BF02514654.

An increase in the use of opioid derivatives in the treatment of pain syndrome in clinical practice, and especially in the treatment of cancer, has added impetus to the search for an agent which does not induce tolerance and...

Disorders of the oral cavity in Parkinson's disease and parkinsonian syndromes.

Parkinson's disease

Zlotnik Y, Balash Y, Korczyn AD, Giladi N, Gurevich T.
PMID: 25685594
Parkinsons Dis. 2015;2015:379482. doi: 10.1155/2015/379482. Epub 2015 Jan 15.

Awareness of nonmotor symptoms of Parkinson's disease is growing during the last decade. Among these, oral cavity disorders are, although prevalent, often neglected by the patients, their caregivers, and physicians. Some of these disorders include increased prevalence of caries...

Computerized diagnosis of mild cognitive impairment.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Aharonson V, Halperin I, Korczyn AD.
PMID: 19595913
Alzheimers Dement. 2007 Jan;3(1):23-7. doi: 10.1016/j.jalz.2006.10.001.

BACKGROUND: We previously described software that we have developed for use in the evaluation of mild cognitive impairment (MCI). Our previous study included an aged nondemented population with memory complaints (n = 41) that was relatively homogenous in terms...

The tropicamide eye drop test in Parkinson's disease.

Parkinsonism & related disorders

Inzelberge R, Feiler V, Korzcyn AD.
PMID: 18591079
Parkinsonism Relat Disord. 1997 Dec;3(4):215-8. doi: 10.1016/s1353-8020(97)00023-0.

The dementia of Parkinson's disease (PD) and Alzheimer's disease (AD) share neurochemical and neuroanatomical characteristics. Pupillary supersensitivity to dilute pilocarpine and to the cholinergic antagonist tropicamide were described in AD, although the specificity has been debated. In the present...

Retraction: familial Alzheimer's disease associated with S182 codon 286 mutation.

Lancet (London, England)

Chapman J, Korczyn AD, Goldfarb LG.
PMID: 8691968
Lancet. 1996 Jul 20;348(9021):206. doi: 10.1016/s0140-6736(05)66162-4.

No abstract available.

CSF tau correlates with CJD disease severity and cognitive decline.

Acta neurologica Scandinavica

Cohen OS, Chapman J, Korczyn AD, Warman-Alaluf N, Nitsan Z, Appel S, Kahana E, Rosenmann H.
PMID: 26014384
Acta Neurol Scand. 2016 Feb;133(2):119-123. doi: 10.1111/ane.12441. Epub 2015 May 25.

BACKGROUND: Creutzfeldt-Jakob disease (CJD) is the most common prion disease in humans. The clinical diagnosis of CJD is supported by a combination of electroencephalogram, MRI, and the presence in the CSF of biomarkers. CSF tau is a marker for...

Hamilton Depression Scale in dementia.

International journal of psychiatry in clinical practice

Kertzman SG, Treves IA, Treves TA, Vainder M, Korczyn AD.
PMID: 24931934
Int J Psychiatry Clin Pract. 2002;6(2):91-4. doi: 10.1080/136515002753724081.

INTRODUCTION: Wide variations in frequency of depression in primary degenerative dementia (PDD) and in vascular dementia (VD) have been reported. This may perhaps be due to inadequacy of common diagnostic tools in detecting depression in the face of cognitive...

A Randomised, Double-Blind, Placebo-Controlled Trial of Actovegin in Patients with Post-Stroke Cognitive Impairment: ARTEMIDA Study Design.

Dementia and geriatric cognitive disorders extra

Guekht A, Skoog I, Korczyn AD, Zakharov V, Eeg M, Vigonius U.
PMID: 24516413
Dement Geriatr Cogn Dis Extra. 2013 Dec 14;3(1):459-67. doi: 10.1159/000357122. eCollection 2013 Jan.

BACKGROUND: No drug treatment to date has shown convincing clinical evidence of restoring cognitive function or preventing further decline after stroke. The ongoing ARTEMIDA study will evaluate the efficacy and safety of Actovegin for the symptomatic treatment of post-stroke...

Drug treatment of Parkinson's disease.

Dialogues in clinical neuroscience

Korczyn AD.
PMID: 22033779
Dialogues Clin Neurosci. 2004 Sep;6(3):315-22.

Parkinson's disease (PD) is a common neurodegenerative disease. While its cause remains elusive, much progress has been made regarding its treatment. Available drugs have a good symptomatic effect, but none has yet been shown to slow the progression of...

Showing 13 to 24 of 30 entries