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Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis.

Cancer genetics

Kovach AE, Zerkalenkova E, Zemtsova L, Borkovskaya A, Gaskova M, Kazanov M, Popov A, Baidun L, Maschan M, Maschan A, Gaynon PS, Bhojwani D, Novichkova G, Olshanskaya Y, Raca G.
PMID: 34915342
Cancer Genet. 2022 Jan;260:37-40. doi: 10.1016/j.cancergen.2021.11.007. Epub 2021 Dec 05.

Pediatric acute myeloid leukemia (AML) is genetically heterogenous (Olsson et al., 2016). t(X;6)(p11;q23) is a rare but recurrent chromosomal translocation in infant AML thought to be associated with male sex and basophilic differentiation (Dastugue et al., 1997). Here we...

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Kovach AE, Zerkalenkova E, Zemtsova L, et al. Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis. Cancer Genet. 2021;260:37-40doi: 10.1016/j.cancergen.2021.11.007.
Kovach, A. E., Zerkalenkova, E., Zemtsova, L., Borkovskaya, A., Gaskova, M., Kazanov, M., Popov, A., Baidun, L., Maschan, M., Maschan, A., Gaynon, P. S., Bhojwani, D., Novichkova, G., Olshanskaya, Y., & Raca, G. (2022). Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis. Cancer genetics, 26037-40. https://doi.org/10.1016/j.cancergen.2021.11.007
Kovach, Alexandra E, et al. "Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis." Cancer genetics vol. 260 (2022): 37-40. doi: https://doi.org/10.1016/j.cancergen.2021.11.007
Kovach AE, Zerkalenkova E, Zemtsova L, Borkovskaya A, Gaskova M, Kazanov M, Popov A, Baidun L, Maschan M, Maschan A, Gaynon PS, Bhojwani D, Novichkova G, Olshanskaya Y, Raca G. Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis. Cancer Genet. 2022 Jan;260:37-40. doi: 10.1016/j.cancergen.2021.11.007. Epub 2021 Dec 05. PMID: 34915342.
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Predictive performance and metabolite dynamics of proton MR spectroscopy in neonatal hypoxic-ischemic encephalopathy.

Pediatric research

Barta H, Jermendy A, Kovacs L, Schiever N, Rudas G, Szabo M.
PMID: 34489532
Pediatr Res. 2021 Sep 06; doi: 10.1038/s41390-021-01626-z. Epub 2021 Sep 06.

BACKGROUND: Prognostic value of proton MR spectroscopy (H-MRS) in hypoxic-ischemic encephalopathy (HIE) is acknowledged; however, effects of gestational age (GA) and postnatal age (PA) on prediction and metabolite levels are unknown.METHODS: One hundred and sixty-nine newborns with moderate-to-severe HIE...

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Barta H, Jermendy A, Kovacs L, et al. Predictive performance and metabolite dynamics of proton MR spectroscopy in neonatal hypoxic-ischemic encephalopathy. Pediatr Res. 2021;doi: 10.1038/s41390-021-01626-z.
Barta, H., Jermendy, A., Kovacs, L., Schiever, N., Rudas, G., & Szabo, M. (2021). Predictive performance and metabolite dynamics of proton MR spectroscopy in neonatal hypoxic-ischemic encephalopathy. Pediatric research, . https://doi.org/10.1038/s41390-021-01626-z
Barta, Hajnalka, et al. "Predictive performance and metabolite dynamics of proton MR spectroscopy in neonatal hypoxic-ischemic encephalopathy." Pediatric research vol. (2021). doi: https://doi.org/10.1038/s41390-021-01626-z
Barta H, Jermendy A, Kovacs L, Schiever N, Rudas G, Szabo M. Predictive performance and metabolite dynamics of proton MR spectroscopy in neonatal hypoxic-ischemic encephalopathy. Pediatr Res. 2021 Sep 06; doi: 10.1038/s41390-021-01626-z. Epub 2021 Sep 06. PMID: 34489532.
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Behavioral, affective, and social correlates of involvement in cross-sex friendship in elementary school.

Child development

Kovacs DM, Parker JG, Hoffman LW.
PMID: 9022241
Child Dev. 1996 Oct;67(5):2269-86.

The purpose of this study was to compare children with and without cross-sex friends on measures of social and cognitive competence, endorsement of sex-role stereotypes, and family composition. Subjects were 723 third and fourth graders (377 girls, 346 boys)...

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Kovacs DM, Parker JG, Hoffman LW. Behavioral, affective, and social correlates of involvement in cross-sex friendship in elementary school. Child Dev. 1996;67(5):2269-86
Kovacs, D. M., Parker, J. G., & Hoffman, L. W. (1996). Behavioral, affective, and social correlates of involvement in cross-sex friendship in elementary school. Child development, 67(5), 2269-86.
Kovacs, D M, et al. "Behavioral, affective, and social correlates of involvement in cross-sex friendship in elementary school." Child development vol. 67,5 (1996): 2269-86.
Kovacs DM, Parker JG, Hoffman LW. Behavioral, affective, and social correlates of involvement in cross-sex friendship in elementary school. Child Dev. 1996 Oct;67(5):2269-86. PMID: 9022241.
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Advanced age exacerbates intestinal epithelial permeability after burn injury in mice.

Experimental gerontology

Najarro KM, Boe DM, Walrath TM, Mullen JE, Paul MT, Frankel JH, Hulsebus HJ, Idrovo JP, McMahan RH, Kovacs EJ.
PMID: 34915110
Exp Gerontol. 2022 Feb;158:111654. doi: 10.1016/j.exger.2021.111654. Epub 2021 Dec 13.

BACKGROUND: Advanced age is an independent risk factor for morbidity and mortality after burn injury. Following burn, the intestines can become permeable leading to the leakage of bacteria and their products from the lumen of the ileum to the...

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Najarro KM, Boe DM, Walrath TM, et al. Advanced age exacerbates intestinal epithelial permeability after burn injury in mice. Exp Gerontol. 2021;158:111654doi: 10.1016/j.exger.2021.111654.
Najarro, K. M., Boe, D. M., Walrath, T. M., Mullen, J. E., Paul, M. T., Frankel, J. H., Hulsebus, H. J., Idrovo, J. P., McMahan, R. H., & Kovacs, E. J. (2022). Advanced age exacerbates intestinal epithelial permeability after burn injury in mice. Experimental gerontology, 158111654. https://doi.org/10.1016/j.exger.2021.111654
Najarro, Kevin M, et al. "Advanced age exacerbates intestinal epithelial permeability after burn injury in mice." Experimental gerontology vol. 158 (2022): 111654. doi: https://doi.org/10.1016/j.exger.2021.111654
Najarro KM, Boe DM, Walrath TM, Mullen JE, Paul MT, Frankel JH, Hulsebus HJ, Idrovo JP, McMahan RH, Kovacs EJ. Advanced age exacerbates intestinal epithelial permeability after burn injury in mice. Exp Gerontol. 2022 Feb;158:111654. doi: 10.1016/j.exger.2021.111654. Epub 2021 Dec 13. PMID: 34915110.
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HDAC6 Activates ERK in Airway and Pulmonary Vascular Remodeling of Chronic Obstructive Pulmonary Disease.

American journal of respiratory cell and molecular biology

Su Y, Han W, Kovacs-Kasa A, Verin AD, Kovacs L.
PMID: 34280336
Am J Respir Cell Mol Biol. 2021 Dec;65(6):603-614. doi: 10.1165/rcmb.2020-0520OC.

Chronic obstructive pulmonary disease (COPD) is a multisystemic respiratory disease that is associated with progressive airway and pulmonary vascular remodeling due to the increased proliferation of bronchial smooth muscles cells (BSMCs) and pulmonary arterial smooth muscle cells (PASMCs) and...

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Su Y, Han W, Kovacs-Kasa A, et al. HDAC6 Activates ERK in Airway and Pulmonary Vascular Remodeling of Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2021;65(6):603-614doi: 10.1165/rcmb.2020-0520OC.
Su, Y., Han, W., Kovacs-Kasa, A., Verin, A. D., & Kovacs, L. (2021). HDAC6 Activates ERK in Airway and Pulmonary Vascular Remodeling of Chronic Obstructive Pulmonary Disease. American journal of respiratory cell and molecular biology, 65(6), 603-614. https://doi.org/10.1165/rcmb.2020-0520OC
Su, Yunchao, et al. "HDAC6 Activates ERK in Airway and Pulmonary Vascular Remodeling of Chronic Obstructive Pulmonary Disease." American journal of respiratory cell and molecular biology vol. 65,6 (2021): 603-614. doi: https://doi.org/10.1165/rcmb.2020-0520OC
Su Y, Han W, Kovacs-Kasa A, Verin AD, Kovacs L. HDAC6 Activates ERK in Airway and Pulmonary Vascular Remodeling of Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2021 Dec;65(6):603-614. doi: 10.1165/rcmb.2020-0520OC. PMID: 34280336; PMCID: PMC8641801.
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Mercury exposure of tidal marsh songbirds in the northeastern United States and its association with nest survival.

Ecotoxicology (London, England)

Ruskin KJ, Herring G, Eagles-Smith CA, Eiklor AB, Elphick CS, Etterson MA, Field CR, Longenecker RA, Kovach AI, Gregory Shriver W, Walsh J, Olsen BJ.
PMID: 34783931
Ecotoxicology. 2021 Nov 16; doi: 10.1007/s10646-021-02488-1. Epub 2021 Nov 16.

The biogeochemistry of tidal marsh sediments facilitates the transformation of mercury (Hg) into the biologically available form methylmercury (MeHg), resulting in elevated Hg exposures to tidal marsh wildlife. Saltmarsh and Acadian Nelson's sparrows (Ammospiza caudacutua and A. nelsoni subvirgatus,...

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Ruskin KJ, Herring G, Eagles-Smith CA, et al. Mercury exposure of tidal marsh songbirds in the northeastern United States and its association with nest survival. Ecotoxicology. 2021;doi: 10.1007/s10646-021-02488-1.
Ruskin, K. J., Herring, G., Eagles-Smith, C. A., Eiklor, A. B., Elphick, C. S., Etterson, M. A., Field, C. R., Longenecker, R. A., Kovach, A. I., Gregory Shriver, W., Walsh, J., & Olsen, B. J. (2021). Mercury exposure of tidal marsh songbirds in the northeastern United States and its association with nest survival. Ecotoxicology (London, England), . https://doi.org/10.1007/s10646-021-02488-1
Ruskin, Katharine J, et al. "Mercury exposure of tidal marsh songbirds in the northeastern United States and its association with nest survival." Ecotoxicology (London, England) vol. (2021). doi: https://doi.org/10.1007/s10646-021-02488-1
Ruskin KJ, Herring G, Eagles-Smith CA, Eiklor AB, Elphick CS, Etterson MA, Field CR, Longenecker RA, Kovach AI, Gregory Shriver W, Walsh J, Olsen BJ. Mercury exposure of tidal marsh songbirds in the northeastern United States and its association with nest survival. Ecotoxicology. 2021 Nov 16; doi: 10.1007/s10646-021-02488-1. Epub 2021 Nov 16. PMID: 34783931.
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Ultrasound-Based Indications for Thyroid Fine-Needle Aspiration: Outcome of a TIRADS-Based Approach versus Operators' Expertise.

European thyroid journal

Solymosi T, Hegedüs L, Bonnema SJ, Frasoldati A, Jambor L, Kovacs GL, Papini E, Rucz K, Russ G, Karanyi Z, Nagy EV.
PMID: 34540712
Eur Thyroid J. 2021 Jul;10(5):416-424. doi: 10.1159/000511183. Epub 2020 Nov 25.

BACKGROUND: Thyroid nodule image reporting and data systems (TIRADS) provide the indications for fine-needle aspiration (FNA) based on a combination of nodule sonographic features and size. We compared the TIRADS-based recommendations for FNA with those based on the personal...

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Solymosi T, Hegedüs L, Bonnema SJ, et al. Ultrasound-Based Indications for Thyroid Fine-Needle Aspiration: Outcome of a TIRADS-Based Approach versus Operators' Expertise. Eur Thyroid J. 2020;10(5):416-424doi: 10.1159/000511183.
Solymosi, T., Hegedüs, L., Bonnema, S. J., Frasoldati, A., Jambor, L., Kovacs, G. L., Papini, E., Rucz, K., Russ, G., Karanyi, Z., & Nagy, E. V. (2021). Ultrasound-Based Indications for Thyroid Fine-Needle Aspiration: Outcome of a TIRADS-Based Approach versus Operators' Expertise. European thyroid journal, 10(5), 416-424. https://doi.org/10.1159/000511183
Solymosi, Tamas, et al. "Ultrasound-Based Indications for Thyroid Fine-Needle Aspiration: Outcome of a TIRADS-Based Approach versus Operators' Expertise." European thyroid journal vol. 10,5 (2021): 416-424. doi: https://doi.org/10.1159/000511183
Solymosi T, Hegedüs L, Bonnema SJ, Frasoldati A, Jambor L, Kovacs GL, Papini E, Rucz K, Russ G, Karanyi Z, Nagy EV. Ultrasound-Based Indications for Thyroid Fine-Needle Aspiration: Outcome of a TIRADS-Based Approach versus Operators' Expertise. Eur Thyroid J. 2021 Jul;10(5):416-424. doi: 10.1159/000511183. Epub 2020 Nov 25. PMID: 34540712; PMCID: PMC8406242.
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Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice.

International journal of molecular sciences

Kovacs L, Bruder-Nascimento T, Greene L, Kennard S, Belin de Chantemèle EJ.
PMID: 34681637
Int J Mol Sci. 2021 Oct 12;22(20). doi: 10.3390/ijms222010977.

People living with human immunodeficiency virus (HIV) (PLWH) have increased risk for atherosclerosis-related cardiovascular disease (CVD), the main cause of death in this population. Notwithstanding, the mechanisms of HIV-associated vascular pathogenesis are not fully elucidated. Therefore, we sought to...

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Kovacs L, Bruder-Nascimento T, Greene L, et al. Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice. Int J Mol Sci. 2021;22(20)doi: 10.3390/ijms222010977.
Kovacs, L., Bruder-Nascimento, T., Greene, L., Kennard, S., & Belin de Chantemèle, E. J. (2021). Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice. International journal of molecular sciences, 22(20), . https://doi.org/10.3390/ijms222010977
Kovacs, Laszlo, et al. "Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice." International journal of molecular sciences vol. 22,20 (2021). doi: https://doi.org/10.3390/ijms222010977
Kovacs L, Bruder-Nascimento T, Greene L, Kennard S, Belin de Chantemèle EJ. Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice. Int J Mol Sci. 2021 Oct 12;22(20). doi: 10.3390/ijms222010977. PMID: 34681637; PMCID: PMC8540571.
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Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles.

Autophagy

Jipa A, Vedelek V, Merényi Z, Ürmösi A, Takáts S, Kovács AL, Horváth GV, Sinka R, Juhász G.
PMID: 33249988
Autophagy. 2021 Sep;17(9):2565-2575. doi: 10.1080/15548627.2020.1856494. Epub 2020 Dec 17.

Yeast Atg8 and its homologs are involved in autophagosome biogenesis in all eukaryotes. These are the most widely used markers for autophagy thanks to the association of their lipidated forms with autophagic membranes. The Atg8 protein family expanded in...

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Jipa A, Vedelek V, Merényi Z, et al. Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles. Autophagy. 2020;17(9):2565-2575doi: 10.1080/15548627.2020.1856494.
Jipa, A., Vedelek, V., Merényi, Z., Ürmösi, A., Takáts, S., Kovács, A. L., Horváth, G. V., Sinka, R., & Juhász, G. (2021). Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles. Autophagy, 17(9), 2565-2575. https://doi.org/10.1080/15548627.2020.1856494
Jipa, András, et al. "Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles." Autophagy vol. 17,9 (2021): 2565-2575. doi: https://doi.org/10.1080/15548627.2020.1856494
Jipa A, Vedelek V, Merényi Z, Ürmösi A, Takáts S, Kovács AL, Horváth GV, Sinka R, Juhász G. Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles. Autophagy. 2021 Sep;17(9):2565-2575. doi: 10.1080/15548627.2020.1856494. Epub 2020 Dec 17. PMID: 33249988; PMCID: PMC8496532.
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Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis.

Cancer genetics

Kovach AE, Zerkalenkova E, Zemtsova L, Borkovskaya A, Gaskova M, Kazanov M, Popov A, Baidun L, Maschan M, Maschan A, Gaynon PS, Bhojwani D, Novichkova G, Olshanskaya Y, Raca G.
PMID: 34915342
Cancer Genet. 2021 Dec 05;260:37-40. doi: 10.1016/j.cancergen.2021.11.007. Epub 2021 Dec 05.

Pediatric acute myeloid leukemia (AML) is genetically heterogenous (Olsson et al., 2016). t(X;6)(p11;q23) is a rare but recurrent chromosomal translocation in infant AML thought to be associated with male sex and basophilic differentiation (Dastugue et al., 1997). Here we...

Cite
Kovach AE, Zerkalenkova E, Zemtsova L, et al. Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis. Cancer Genet. 2021;260:37-40doi: 10.1016/j.cancergen.2021.11.007.
Kovach, A. E., Zerkalenkova, E., Zemtsova, L., Borkovskaya, A., Gaskova, M., Kazanov, M., Popov, A., Baidun, L., Maschan, M., Maschan, A., Gaynon, P. S., Bhojwani, D., Novichkova, G., Olshanskaya, Y., & Raca, G. (2021). Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis. Cancer genetics, 26037-40. https://doi.org/10.1016/j.cancergen.2021.11.007
Kovach, Alexandra E, et al. "Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis." Cancer genetics vol. 260 (2021): 37-40. doi: https://doi.org/10.1016/j.cancergen.2021.11.007
Kovach AE, Zerkalenkova E, Zemtsova L, Borkovskaya A, Gaskova M, Kazanov M, Popov A, Baidun L, Maschan M, Maschan A, Gaynon PS, Bhojwani D, Novichkova G, Olshanskaya Y, Raca G. Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis. Cancer Genet. 2021 Dec 05;260:37-40. doi: 10.1016/j.cancergen.2021.11.007. Epub 2021 Dec 05. PMID: 34915342.
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In Response.

Anesthesia and analgesia

Jin Z, Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, Kovac AL, Meyer TA, Urman RD, Apfel CC, Ayad S, Beagley L, Candiotti K, Englesakis M, Hedrick TL, Kranke P, Lee S, Lipman D, Minkowitz HS, Morton J, Philip BK.
PMID: 33449569
Anesth Analg. 2021 Feb 01;132(2):e31-e33. doi: 10.1213/ANE.0000000000005280.

No abstract available.

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Jin Z, Gan TJ, Belani KG, et al. In Response. Anesth Analg. 2021;132(2):e31-e33doi: 10.1213/ANE.0000000000005280.
Jin, Z., Gan, T. J., Belani, K. G., Bergese, S., Chung, F., Diemunsch, P., Habib, A. S., Kovac, A. L., Meyer, T. A., Urman, R. D., Apfel, C. C., Ayad, S., Beagley, L., Candiotti, K., Englesakis, M., Hedrick, T. L., Kranke, P., Lee, S., Lipman, D., Minkowitz, H. S., Morton, J., & Philip, B. K. (2021). In Response. Anesthesia and analgesia, 132(2), e31-e33. https://doi.org/10.1213/ANE.0000000000005280
Jin, Zhaosheng, et al. "In Response." Anesthesia and analgesia vol. 132,2 (2021): e31-e33. doi: https://doi.org/10.1213/ANE.0000000000005280
Jin Z, Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, Kovac AL, Meyer TA, Urman RD, Apfel CC, Ayad S, Beagley L, Candiotti K, Englesakis M, Hedrick TL, Kranke P, Lee S, Lipman D, Minkowitz HS, Morton J, Philip BK. In Response. Anesth Analg. 2021 Feb 01;132(2):e31-e33. doi: 10.1213/ANE.0000000000005280. PMID: 33449569.
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Thermal Degradants Identified from the Vaping of Vitamin E Acetate.

Journal of analytical toxicology

Kovach AL, Carter RR, Thornburg JW, Wiethe R, Fennell TR, Wiley JL.
PMID: 34666345
J Anal Toxicol. 2021 Oct 20; doi: 10.1093/jat/bkab109. Epub 2021 Oct 20.

Studies have suggested that vitamin E acetate (VEA), when used in an electronic vaping device, undergoes thermal degradation and is considered one of the main contributors in E-cigarette or Vaping product use-Associated Lung Injury (EVALI). Using a Borgwaldt 5.1...

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Kovach AL, Carter RR, Thornburg JW, et al. Thermal Degradants Identified from the Vaping of Vitamin E Acetate. J Anal Toxicol. 2021;doi: 10.1093/jat/bkab109.
Kovach, A. L., Carter, R. R., Thornburg, J. W., Wiethe, R., Fennell, T. R., & Wiley, J. L. (2021). Thermal Degradants Identified from the Vaping of Vitamin E Acetate. Journal of analytical toxicology, . https://doi.org/10.1093/jat/bkab109
Kovach, Alexander L, et al. "Thermal Degradants Identified from the Vaping of Vitamin E Acetate." Journal of analytical toxicology vol. (2021). doi: https://doi.org/10.1093/jat/bkab109
Kovach AL, Carter RR, Thornburg JW, Wiethe R, Fennell TR, Wiley JL. Thermal Degradants Identified from the Vaping of Vitamin E Acetate. J Anal Toxicol. 2021 Oct 20; doi: 10.1093/jat/bkab109. Epub 2021 Oct 20. PMID: 34666345.
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