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Showing 13 to 24 of 142 entries
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An in vitro method for screening for the presence of thepat-2 gene in tomatoes (Lycopersicon esculentum Mill.).

Plant cell reports

Young TE, Juvik JA, Sullivan JG, Skirvin RM.
PMID: 24226281
Plant Cell Rep. 1990 Jan;8(9):538-41. doi: 10.1007/BF00820204.

Under field conditions,pat-2, the gene which conditions parthenocarpy in tomatoes, is recessive. A simple method has been devised for distinguishing the heterozygote from the two homozygotes using tissue culture. Ovaries of plants segregating for thepat-2 gene were excised and...

Ion-energy effects in silicon ion-beam epitaxy.

Physical review. B, Condensed matter

Al-Bayati AH, Boyd KJ, Chu WK, Kulik J, Marton D, Rabalais JW, Zhang Z.
PMID: 9982646
Phys Rev B Condens Matter. 1996 Apr 15;53(16):10781-10792. doi: 10.1103/physrevb.53.10781.

No abstract available.

Photocatalytic C-F alkylation; facile access to multifluorinated arenes.

Chemical science

Singh A, Kubik JJ, Weaver JD.
PMID: 29861956
Chem Sci. 2015 Dec 01;6(12):7206-7212. doi: 10.1039/c5sc03013g. Epub 2015 Sep 29.

C-F functionalizations that provide C-C bonds are challenging synthetic transformations, due in part to the large C-F bond strength, short bond length, nonpolarizable nature, the production of fluoride, and the regioselectivity-in the case of multifluorinated substrates. However, commercially available...

Birth defect survival for Hispanic subgroups.

Birth defects research

Lopez KN, Nembhard WN, Wang Y, Liu G, Kucik JE, Copeland G, Gilboa SM, Kirby RS, Canfield M.
PMID: 29195034
Birth Defects Res. 2018 Mar 01;110(4):352-363. doi: 10.1002/bdr2.1157. Epub 2017 Dec 01.

BACKGROUND: Previous studies demonstrate that infant and childhood mortality differ among children with birth defects by maternal race/ethnicity, but limited mortality information is published for Hispanic ethnic subgroups.METHODS: We performed a retrospective cohort study using data for children with...

The Role of Glucosinolate Hydrolysis Products from Brassica Vegetable Consumption in Inducing Antioxidant Activity and Reducing Cancer Incidence.

Diseases (Basel, Switzerland)

Becker TM, Juvik JA.
PMID: 28933402
Diseases. 2016 Jun 17;4(2). doi: 10.3390/diseases4020022.

The bioactivity of glucosinolates (GSs), and more specifically their hydrolysis products (GSHPs), has been well documented. These secondary metabolites evolved in the order Brassicales as plant defense compounds with proven ability to deter or impede the growth of several...

Characterization of the Actinonin Biosynthetic Gene Cluster.

Chembiochem : a European journal of chemical biology

Wolf F, Leipoldt F, Kulik A, Wibberg D, Kalinowski J, Kaysser L.
PMID: 29600569
Chembiochem. 2018 Mar 30; doi: 10.1002/cbic.201800116. Epub 2018 Mar 30.

The hydroxamate moiety of the natural product actinonin mediates inhibition of metalloproteinases because of its chelating properties towards divalent cations in the active site of those enzymes. Owing to its antimicrobial activity, actinonin has served as a lead compound...

Integrating Subjective and Objective Dimensions of Resilience in Fire-Prone Landscapes.

Bioscience

Higuera PE, Metcalf AL, Miller C, Buma B, McWethy DB, Metcalf EC, Ratajczak Z, Nelson CR, Chaffin BC, Stedman RC, McCaffrey S, Schoennagel T, Harvey BJ, Hood SM, Schultz CA, Black AE, Campbell D, Haggerty JH, Keane RE, Krawchuk MA, Kulig JC, Rafferty R, Virapongse A.
PMID: 31086421
Bioscience. 2019 May 01;69(5):379-388. doi: 10.1093/biosci/biz030. Epub 2019 May 08.

Resilience has become a common goal for science-based natural resource management, particularly in the context of changing climate and disturbance regimes. Integrating varying perspectives and definitions of resilience is a complex and often unrecognized challenge to applying resilience concepts...

A Computer Program for a Trilinear Diagram Plot and Analysis of Water Mixing Systems.

Ground water

Morris MD, Berk JA, Krulik JW, Eckstein Y.
PMID: 29991174
Ground Water. 1983 Jan;21(1):67-78. doi: 10.1111/j.1745-6584.1983.tb00706.x.

The Piper (1953) trilinear diagram has been widely used to graphically represent the dissolved constituents of natural waters and to test for apparent mixtures of waters from different sources. Because of the time required to plot points and calculate...

HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway.

Nature communications

Smith AE, Ferraro E, Safonov A, Morales CB, Lahuerta EJA, Li Q, Kulick A, Ross D, Solit DB, de Stanchina E, Reis-Filho J, Rosen N, Arribas J, Razavi P, Chandarlapaty S.
PMID: 34795269
Nat Commun. 2021 Nov 18;12(1):6667. doi: 10.1038/s41467-021-27093-y.

Inhibition of HER2 in HER2-amplified breast cancer has been remarkably successful clinically, as demonstrated by the efficacy of HER-kinase inhibitors and HER2-antibody treatments. Whilst resistance to HER2 inhibition is common in the metastatic setting, the specific programs downstream of...

Stereodivergent Nitrocyclopropane Formation during Biosynthesis of Belactosins and Hormaomycins.

Journal of the American Chemical Society

Shimo S, Ushimaru R, Engelbrecht A, Harada M, Miyamoto K, Kulik A, Uchiyama M, Kaysser L, Abe I, Chapman RS.
PMID: 34710328
J Am Chem Soc. 2021 Nov 10;143(44):18413-18418. doi: 10.1021/jacs.1c10201. Epub 2021 Oct 28.

Belactosins and hormaomycins are peptide natural products containing 3-(2-aminocyclopropyl)alanine and 3-(2-nitrocyclopropyl)alanine residues, respectively, with opposite stereoconfigurations of the cyclopropane ring. Herein we demonstrate that the heme oxygenase-like enzymes BelK and HrmI catalyze the N-oxygenation of l-lysine to generate 6-nitronorleucine....

Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability.

Protein science : a publication of the Protein Society

Kulik AA, Maruszczak KK, Thomas DC, Nabi-Aldridge NLA, Carr M, Bingham RJ, Cooper CDO.
PMID: 33884680
Protein Sci. 2021 Jun;30(6):1196-1209. doi: 10.1002/pro.4085. Epub 2021 May 10.

Polymerase δ-interacting protein 2 (POLDIP2, PDIP38) is a multifaceted, "moonlighting" protein, involved in binding protein partners from many different cellular processes, including mitochondrial metabolism and DNA replication and repair. How POLDIP2 interacts with many different proteins is unknown. Towards...

Jornal vascular brasileiro

Di Santo MK, Takemoto D, Nascimento RG, Nascimento AM, Siqueira É, Duarte CT, Jovino MAC, Kalil JA.
PMID: 29930634
J Vasc Bras. 2017 Apr-Jun;16(2):104-112. doi: 10.1590/1677-5449.011516.

No abstract available.

Showing 13 to 24 of 142 entries