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CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology.

Vaccines

DeMarco JK, Royal JM, Severson WE, Gabbard JD, Hume S, Morton J, Swope K, Simpson CA, Shepherd JW, Bratcher B, Palmer KE, Pogue GP.
PMID: 34835277
Vaccines (Basel). 2021 Nov 17;9(11). doi: 10.3390/vaccines9111346.

We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits strong antibody responses in C57BL/6...

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DeMarco JK, Royal JM, Severson WE, et al. CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology. Vaccines (Basel). 2021;9(11)doi: 10.3390/vaccines9111346.
DeMarco, J. K., Royal, J. M., Severson, W. E., Gabbard, J. D., Hume, S., Morton, J., Swope, K., Simpson, C. A., Shepherd, J. W., Bratcher, B., Palmer, K. E., & Pogue, G. P. (2021). CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology. Vaccines, 9(11), . https://doi.org/10.3390/vaccines9111346
DeMarco, Jennifer K, et al. "CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology." Vaccines vol. 9,11 (2021). doi: https://doi.org/10.3390/vaccines9111346
DeMarco JK, Royal JM, Severson WE, Gabbard JD, Hume S, Morton J, Swope K, Simpson CA, Shepherd JW, Bratcher B, Palmer KE, Pogue GP. CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology. Vaccines (Basel). 2021 Nov 17;9(11). doi: 10.3390/vaccines9111346. PMID: 34835277; PMCID: PMC8618284.
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The prevalence of current smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer among participants in a community-based cardiometabolic screening program in Miyagi prefecture, Japan: a comparison with nationally representative surveys in other countries.

Cancer medicine

Nishimoto Y, Tsubono Y, Kogure M, Nakamura T, Itabashi F, Tsuchiya N, Nakaya N, Tanno K, Sugawara J, Kuriyama S, Kure S, Tsuji I, Hozawa A.
PMID: 34850586
Cancer Med. 2021 Dec;10(24):9000-9011. doi: 10.1002/cam4.4364. Epub 2021 Dec 01.

BACKGROUND: We determined the prevalence of current cigarette smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer in Japan and compared the findings with nationally representative studies in other countries.METHODS: We conducted a cross-sectional...

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Nishimoto Y, Tsubono Y, Kogure M, et al. The prevalence of current smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer among participants in a community-based cardiometabolic screening program in Miyagi prefecture, Japan: a comparison with nationally representative surveys in other countries. Cancer Med. 2021;10(24):9000-9011doi: 10.1002/cam4.4364.
Nishimoto, Y., Tsubono, Y., Kogure, M., Nakamura, T., Itabashi, F., Tsuchiya, N., Nakaya, N., Tanno, K., Sugawara, J., Kuriyama, S., Kure, S., Tsuji, I., & Hozawa, A. (2021). The prevalence of current smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer among participants in a community-based cardiometabolic screening program in Miyagi prefecture, Japan: a comparison with nationally representative surveys in other countries. Cancer medicine, 10(24), 9000-9011. https://doi.org/10.1002/cam4.4364
Nishimoto, Yuka, et al. "The prevalence of current smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer among participants in a community-based cardiometabolic screening program in Miyagi prefecture, Japan: a comparison with nationally representative surveys in other countries." Cancer medicine vol. 10,24 (2021): 9000-9011. doi: https://doi.org/10.1002/cam4.4364
Nishimoto Y, Tsubono Y, Kogure M, Nakamura T, Itabashi F, Tsuchiya N, Nakaya N, Tanno K, Sugawara J, Kuriyama S, Kure S, Tsuji I, Hozawa A. The prevalence of current smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer among participants in a community-based cardiometabolic screening program in Miyagi prefecture, Japan: a comparison with nationally representative surveys in other countries. Cancer Med. 2021 Dec;10(24):9000-9011. doi: 10.1002/cam4.4364. Epub 2021 Dec 01. PMID: 34850586.
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Prognostic significance of concentric left ventricular hypertrophy at peritoneal dialysis initiation.

BMC nephrology

Tomura M, Hamasaki Y, Komaru Y, Miyamoto Y, Matsuura R, Matsumoto A, Doi K, Kume H, Nangaku M.
PMID: 33863299
BMC Nephrol. 2021 Apr 16;22(1):135. doi: 10.1186/s12882-021-02321-1.

BACKGROUND: Concentric left ventricular hypertrophy (cLVH) is a common left ventricular geometric pattern in patients undergoing maintenance dialysis, including peritoneal dialysis (PD). The relationship between cLVH at PD initiation and the prognosis of patients remains unclear, however. This study...

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Tomura M, Hamasaki Y, Komaru Y, et al. Prognostic significance of concentric left ventricular hypertrophy at peritoneal dialysis initiation. BMC Nephrol. 2021;22(1):135doi: 10.1186/s12882-021-02321-1.
Tomura, M., Hamasaki, Y., Komaru, Y., Miyamoto, Y., Matsuura, R., Matsumoto, A., Doi, K., Kume, H., & Nangaku, M. (2021). Prognostic significance of concentric left ventricular hypertrophy at peritoneal dialysis initiation. BMC nephrology, 22(1), 135. https://doi.org/10.1186/s12882-021-02321-1
Tomura, Misato, et al. "Prognostic significance of concentric left ventricular hypertrophy at peritoneal dialysis initiation." BMC nephrology vol. 22,1 (2021): 135. doi: https://doi.org/10.1186/s12882-021-02321-1
Tomura M, Hamasaki Y, Komaru Y, Miyamoto Y, Matsuura R, Matsumoto A, Doi K, Kume H, Nangaku M. Prognostic significance of concentric left ventricular hypertrophy at peritoneal dialysis initiation. BMC Nephrol. 2021 Apr 16;22(1):135. doi: 10.1186/s12882-021-02321-1. PMID: 33863299; PMCID: PMC8052641.
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State-Selective Observation of Radiative Cooling of Vibrationally Excited C.

The journal of physical chemistry letters

Iida S, Kuma S, Tanuma H, Azuma T, Shiromaru H.
PMID: 33289570
J Phys Chem Lett. 2020 Dec 17;11(24):10526-10531. doi: 10.1021/acs.jpclett.0c03196. Epub 2020 Dec 08.

We have observed radiative cooling of vibrationally excited C

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Iida S, Kuma S, Tanuma H, et al. State-Selective Observation of Radiative Cooling of Vibrationally Excited C. J Phys Chem Lett. 2020;11(24):10526-10531doi: 10.1021/acs.jpclett.0c03196.
Iida, S., Kuma, S., Tanuma, H., Azuma, T., & Shiromaru, H. (2020). State-Selective Observation of Radiative Cooling of Vibrationally Excited C. The journal of physical chemistry letters, 11(24), 10526-10531. https://doi.org/10.1021/acs.jpclett.0c03196
Iida, Shimpei, et al. "State-Selective Observation of Radiative Cooling of Vibrationally Excited C." The journal of physical chemistry letters vol. 11,24 (2020): 10526-10531. doi: https://doi.org/10.1021/acs.jpclett.0c03196
Iida S, Kuma S, Tanuma H, Azuma T, Shiromaru H. State-Selective Observation of Radiative Cooling of Vibrationally Excited C. J Phys Chem Lett. 2020 Dec 17;11(24):10526-10531. doi: 10.1021/acs.jpclett.0c03196. Epub 2020 Dec 08. PMID: 33289570.
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GI-SleepNet: A Highly Versatile Image-Based Sleep Classification Using a Deep Learning Algorithm.

Clocks & sleep

Gao T, Li J, Watanabe Y, Hung C, Yamanaka A, Horie K, Yanagisawa M, Ohsawa M, Kume K.
PMID: 34842647
Clocks Sleep. 2021 Nov 01;3(4):581-597. doi: 10.3390/clockssleep3040041.

Sleep-stage classification is essential for sleep research. Various automatic judgment programs, including deep learning algorithms using artificial intelligence (AI), have been developed, but have limitations with regard to data format compatibility, human interpretability, cost, and technical requirements. We developed...

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Gao T, Li J, Watanabe Y, et al. GI-SleepNet: A Highly Versatile Image-Based Sleep Classification Using a Deep Learning Algorithm. Clocks Sleep. 2021;3(4):581-597doi: 10.3390/clockssleep3040041.
Gao, T., Li, J., Watanabe, Y., Hung, C., Yamanaka, A., Horie, K., Yanagisawa, M., Ohsawa, M., & Kume, K. (2021). GI-SleepNet: A Highly Versatile Image-Based Sleep Classification Using a Deep Learning Algorithm. Clocks & sleep, 3(4), 581-597. https://doi.org/10.3390/clockssleep3040041
Gao, Tianxiang, et al. "GI-SleepNet: A Highly Versatile Image-Based Sleep Classification Using a Deep Learning Algorithm." Clocks & sleep vol. 3,4 (2021): 581-597. doi: https://doi.org/10.3390/clockssleep3040041
Gao T, Li J, Watanabe Y, Hung C, Yamanaka A, Horie K, Yanagisawa M, Ohsawa M, Kume K. GI-SleepNet: A Highly Versatile Image-Based Sleep Classification Using a Deep Learning Algorithm. Clocks Sleep. 2021 Nov 01;3(4):581-597. doi: 10.3390/clockssleep3040041. PMID: 34842647; PMCID: PMC8628800.
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Identification of Thermal Response of Mesoscopic Liquids under Mechanical Excitation: From Harmonic to Nonharmonic Thermal Wave.

The journal of physical chemistry. B

Kume E, Noirez L.
PMID: 34296613
J Phys Chem B. 2021 Aug 05;125(30):8652-8658. doi: 10.1021/acs.jpcb.1c04362. Epub 2021 Jul 23.

In the conventional picture, the temperature of a liquid bath in the quiescent state is uniform down to thermal fluctuation length scales. Here we examine the impact of a low-frequency shear mechanical field (hertz) on the thermal equilibrium of...

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Kume E, Noirez L. Identification of Thermal Response of Mesoscopic Liquids under Mechanical Excitation: From Harmonic to Nonharmonic Thermal Wave. J Phys Chem B. 2021;125(30):8652-8658doi: 10.1021/acs.jpcb.1c04362.
Kume, E., & Noirez, L. (2021). Identification of Thermal Response of Mesoscopic Liquids under Mechanical Excitation: From Harmonic to Nonharmonic Thermal Wave. The journal of physical chemistry. B, 125(30), 8652-8658. https://doi.org/10.1021/acs.jpcb.1c04362
Kume, Eni, and Noirez, Laurence. "Identification of Thermal Response of Mesoscopic Liquids under Mechanical Excitation: From Harmonic to Nonharmonic Thermal Wave." The journal of physical chemistry. B vol. 125,30 (2021): 8652-8658. doi: https://doi.org/10.1021/acs.jpcb.1c04362
Kume E, Noirez L. Identification of Thermal Response of Mesoscopic Liquids under Mechanical Excitation: From Harmonic to Nonharmonic Thermal Wave. J Phys Chem B. 2021 Aug 05;125(30):8652-8658. doi: 10.1021/acs.jpcb.1c04362. Epub 2021 Jul 23. PMID: 34296613.
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Impact of the Concomitant Use of Immunomodulator and a Lower Week 8 Partial Mayo Score on the Persistence of Adalimumab in Refractory Ulcerative Colitis.

Internal medicine (Tokyo, Japan)

Kumei S, Sakurai T, So S, Itaba S, Akiho H, Nakamura S, Kim H, Yamasaki M, Takatsu N, Maekawa R, Sakemi R, Watanabe T, Shibata M, Kume K, Yoshikawa I, Takaki Y, Harada M.
PMID: 34121007
Intern Med. 2021 Dec 15;60(24):3849-3856. doi: 10.2169/internalmedicine.7279-21. Epub 2021 Jun 12.

Objective Real-world data of adalimumab (ADA) in the treatment of ulcerative colitis (UC) are scarce. We aimed to study the ADA response rates and predictors of response in UC treatment. Methods This observational, prospective and multi-center study assessed the...

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Kumei S, Sakurai T, So S, et al. Impact of the Concomitant Use of Immunomodulator and a Lower Week 8 Partial Mayo Score on the Persistence of Adalimumab in Refractory Ulcerative Colitis. Intern Med. 2021;60(24):3849-3856doi: 10.2169/internalmedicine.7279-21.
Kumei, S., Sakurai, T., So, S., Itaba, S., Akiho, H., Nakamura, S., Kim, H., Yamasaki, M., Takatsu, N., Maekawa, R., Sakemi, R., Watanabe, T., Shibata, M., Kume, K., Yoshikawa, I., Takaki, Y., & Harada, M. (2021). Impact of the Concomitant Use of Immunomodulator and a Lower Week 8 Partial Mayo Score on the Persistence of Adalimumab in Refractory Ulcerative Colitis. Internal medicine (Tokyo, Japan), 60(24), 3849-3856. https://doi.org/10.2169/internalmedicine.7279-21
Kumei, Shinsuke, et al. "Impact of the Concomitant Use of Immunomodulator and a Lower Week 8 Partial Mayo Score on the Persistence of Adalimumab in Refractory Ulcerative Colitis." Internal medicine (Tokyo, Japan) vol. 60,24 (2021): 3849-3856. doi: https://doi.org/10.2169/internalmedicine.7279-21
Kumei S, Sakurai T, So S, Itaba S, Akiho H, Nakamura S, Kim H, Yamasaki M, Takatsu N, Maekawa R, Sakemi R, Watanabe T, Shibata M, Kume K, Yoshikawa I, Takaki Y, Harada M. Impact of the Concomitant Use of Immunomodulator and a Lower Week 8 Partial Mayo Score on the Persistence of Adalimumab in Refractory Ulcerative Colitis. Intern Med. 2021 Dec 15;60(24):3849-3856. doi: 10.2169/internalmedicine.7279-21. Epub 2021 Jun 12. PMID: 34121007.
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Showing 685 to 691 of 691 entries