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Showing 1261 to 1272 of 1272 entries
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Intraoperative Cerebrospinal Fluid Leak Graded by Esposito Grade Is a Predictor for Diabetes Insipidus After Endoscopic Endonasal Pituitary Adenoma Resection.

World neurosurgery

Tanji M, Mineharu Y, Kikuchi M, Nakagawa T, Sakamoto T, Yamashita M, Matsunaga M, Kuwata F, Kitada Y, Terada Y, Arakawa Y, Yoshida K, Kataoka H, Miyamoto S.
PMID: 34844009
World Neurosurg. 2021 Nov 27; doi: 10.1016/j.wneu.2021.11.090. Epub 2021 Nov 27.

BACKGROUND: Diabetes insipidus (DI) is a well-known complication of transsphenoidal surgery. However, the risk factors for DI remain controversial.METHODS: We conducted a retrospective study of patients who underwent endoscopic transsphenoidal surgery for pituitary adenoma at our institution during a...

Short communication: Distribution of phospholipids in parotid cancer by matrix-assisted laser desorption/ionization imaging mass spectrometry.

PloS one

Kanetake H, Kato-Kogoe N, Terada T, Kurisu Y, Hamada W, Nakajima Y, Hirose Y, Ueno T, Kawata R.
PMID: 34919590
PLoS One. 2021 Dec 17;16(12):e0261491. doi: 10.1371/journal.pone.0261491. eCollection 2021.

BACKGROUND: Parotid cancer is relatively rare, and malignancy varies; therefore, novel markers are needed to predict prognosis. Recent advances in matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS), useful for visualization of lipid molecules, have revealed the relationship between cancer...

Matter of TIME: the tumor-immune microenvironment of mesothelioma and implications for checkpoint blockade efficacy.

Journal for immunotherapy of cancer

Harber J, Kamata T, Pritchard C, Fennell D.
PMID: 34518291
J Immunother Cancer. 2021 Sep;9(9). doi: 10.1136/jitc-2021-003032.

Malignant pleural mesothelioma (MPM) is an incurable cancer with a dismal prognosis and few effective treatment options. Nonetheless, recent positive phase III trial results for immune checkpoint blockade (ICB) in MPM herald a new dawn in the fight to...

Phase 1 study of pembrolizumab plus chemotherapy as first-line treatment in Japanese patients with advanced NSCLC.

Cancer treatment and research communications

Kurata T, Nakagawa K, Satouchi M, Seto T, Sawada T, Han S, Homma M, Noguchi K, Nogami N.
PMID: 34607222
Cancer Treat Res Commun. 2021 Sep 15;29:100458. doi: 10.1016/j.ctarc.2021.100458. Epub 2021 Sep 15.

INTRODUCTION: Pembrolizumab plus chemotherapy significantly improved outcomes over chemotherapy alone as first-line treatment in patients with advanced non-small-cell lung cancer (NSCLC) in phase 3 international trials. In the phase 1 KEYNOTE-011 study (parts B and C), we evaluated the...

Milk intake and depressive symptom: a risk assessment.

The British journal of nutrition

Kawada T.
PMID: 33298233
Br J Nutr. 2021 Sep 28;126(6):956. doi: 10.1017/S0007114520004900. Epub 2020 Dec 10.

No abstract available.

Differential Contribution of the Medial and the Lateral Side of the Joint to Symptoms in Knee Osteoarthritis: A Radiographic and Laboratory Analysis in the Nagahama Study.

Cartilage

Nigoro K, Ito H, Kawata T, Ishie S, Morita Y, Nishitani K, Aoyama T, Tabara Y, Matsuda F, Narumiya S, Matsuda S.
PMID: 34261349
Cartilage. 2021 Dec;13(1):1648S-1657S. doi: 10.1177/19476035211025817. Epub 2021 Jul 14.

OBJECTIVE: This cross-sectional study aimed to explore the differences of the medial and lateral sides of the knee joint and precise radiographic abnormalities in contribution to the knee pain and clinical outcomes.DESIGN: Participants 60 years or older who underwent...

Micro-computed tomography: A novel diagnostic technique for the evaluation of gastrointestinal specimens.

Endoscopy international open

Kawata N, Teplov A, Ntiamoah P, Shia J, Hameed M, Yagi Y.
PMID: 34917457
Endosc Int Open. 2021 Dec 14;9(12):E1886-E1889. doi: 10.1055/a-1546-8063. eCollection 2021 Dec.

Micro-computed tomography (micro-CT) is a non-destructive modality that can be used to obtain high-resolution three-dimensional (3 D) images of the whole sample tissue; the usefulness of micro-CT has been reported for evaluation of breast cancer and lung cancer. However,...

Ultrahigh voltage electron microscopy links neuroanatomy and neuroscience/neuroendocrinology.

Anatomy research international

Sakamoto H, Kawata M.
PMID: 22567316
Anat Res Int. 2012;2012:948704. doi: 10.1155/2012/948704. Epub 2011 Dec 08.

The three-dimensional (3D) analysis of anatomical ultrastructures is extremely important in most fields of biological research. Although it is very difficult to perform 3D image analysis on exact serial sets of ultrathin sections, 3D reconstruction from serial ultrathin sections...

The prevalence and impact of sarcopenia in females undergoing total hip arthroplasty: A prospective study.

Modern rheumatology

Ueoka K, Kabata T, Kajino Y, Inoue D, Ohmori T, Ueno T, Yoshitani J, Yamamuro Y, Taninaka A, Kato S, Yahata T, Tsuchiya H.
PMID: 33719865
Mod Rheumatol. 2021 Mar 30;1-6. doi: 10.1080/14397595.2021.1899603. Epub 2021 Mar 30.

OBJECTIVES: Although both sarcopenia and hip disease decrease physical function, few studies have investigated the association. We investigated the prevalence of sarcopenia in patients awaiting total hip arthroplasty for osteoarthritis and examined the impact of sarcopenia on pre- and...

Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironment.

Disease models & mechanisms

Kamata T, Al Dujaily E, Alhamad S, So TY, Margaritaki O, Giblett S, Pringle JH, Le Quesne J, Pritchard C.
PMID: 34779486
Dis Model Mech. 2022 Feb 01;15(2). doi: 10.1242/dmm.049148. Epub 2022 Jan 04.

Anti-cancer properties of statins are controversial and possibly context dependent. Recent pathology/epidemiology studies of human lung adenocarcinoma showed reduced pro-tumourigenic macrophages associated with a shift to lower-grade tumours amongst statin users but, paradoxically, worse survival compared with that of...

Gamma-Ray Observation of the Cygnus Region in the 100-TeV Energy Region.

Physical review letters

Amenomori M, Bao YW, Bi XJ, Chen D, Chen TL, Chen WY, Chen X, Chen Y, Cirennima, Cui SW, Danzengluobu, Ding LK, Fang JH, Fang K, Feng CF, Feng Z, Feng ZY, Gao Q, Gomi A, Gou QB, Guo YQ, Guo YY, He HH, He ZT, Hibino K, Hotta N, Hu H, Hu HB, Huang J, Jia HY, Jiang L, Jiang P, Jin HB, Kasahara K, Katayose Y, Kato C, Kato S, Kawata K, Kozai M, Kurashige D, Labaciren, Le GM, Li AF, Li HJ, Li WJ, Li Y, Lin YH, Liu B, Liu C, Liu JS, Liu LY, Liu MY, Liu W, Liu XL, Lou YQ, Lu H, Meng XR, Munakata K, Nakada H, Nakamura Y, Nakazawa Y, Nanjo H, Ning CC, Nishizawa M, Ohnishi M, Ohura T, Okukawa S, Ozawa S, Qian L, Qian X, Qian XL, Qu XB, Saito T, Sakata M, Sako T, Sako TK, Shao J, Shibata M, Shiomi A, Sugimoto H, Takano W, Takita M, Tan YH, Tateyama N, Torii S, Tsuchiya H, Udo S, Wang H, Wang YP, Wangdui, Wu HR, Wu Q, Xu JL, Xue L, Yamamoto Y, Yang Z, Yao YQ, Yin J, Yokoe Y, Yu NP, Yuan AF, Zhai LM, Zhang CP, Zhang HM, Zhang JL, Zhang X, Zhang XY, Zhang Y, Zhang Y, Zhang Y, Zhao SP, Zhaxisangzhu, Zhou XX.
PMID: 34328784
Phys Rev Lett. 2021 Jul 16;127(3):031102. doi: 10.1103/PhysRevLett.127.031102.

We report observations of gamma-ray emissions with energies in the 100-TeV energy region from the Cygnus region in our Galaxy. Two sources are significantly detected in the directions of the Cygnus OB1 and OB2 associations. Based on their positional...

Phase I study of weekly nab-paclitaxel plus carboplatin and concurrent thoracic radiotherapy in elderly patients with unresectable locally advanced non-small cell lung cancer.

Investigational new drugs

Omori S, Harada H, Mori K, Hisamatsu Y, Tsuboguchi Y, Yoshioka H, Morinaga R, Daga H, Kurata T, Takahashi T.
PMID: 34495421
Invest New Drugs. 2022 Feb;40(1):106-114. doi: 10.1007/s10637-021-01155-w. Epub 2021 Sep 08.

Few clinical studies have been designed for elderly patients with locally advanced non-small cell lung cancer (NSCLC). We conducted a phase I study to evaluate the tolerability of carboplatin/nab-paclitaxel and concurrent thoracic radiotherapy in elderly patients with locally advanced...

Showing 1261 to 1272 of 1272 entries