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Systemic Antibiotics Influence Periodontal Parameters and Oral Microbiota, But Not Serological Markers.

Frontiers in cellular and infection microbiology

Kopra E, Lahdentausta L, Pietiäinen M, Buhlin K, Mäntylä P, Hörkkö S, Persson R, Paju S, Sinisalo J, Salminen A, Pussinen PJ.
PMID: 35004349
Front Cell Infect Microbiol. 2021 Dec 24;11:774665. doi: 10.3389/fcimb.2021.774665. eCollection 2021.

The use of systemic antibiotics may influence the oral microbiota composition. Our aim was to investigate in this retrospective study whether the use of prescribed antibiotics associate with periodontal status, oral microbiota, and antibodies against the periodontal pathogens. The...

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Kopra E, Lahdentausta L, Pietiäinen M, et al. Systemic Antibiotics Influence Periodontal Parameters and Oral Microbiota, But Not Serological Markers. Front Cell Infect Microbiol. 2021;11:774665doi: 10.3389/fcimb.2021.774665.
Kopra, E., Lahdentausta, L., Pietiäinen, M., Buhlin, K., Mäntylä, P., Hörkkö, S., Persson, R., Paju, S., Sinisalo, J., Salminen, A., & Pussinen, P. J. (2021). Systemic Antibiotics Influence Periodontal Parameters and Oral Microbiota, But Not Serological Markers. Frontiers in cellular and infection microbiology, 11774665. https://doi.org/10.3389/fcimb.2021.774665
Kopra, Elisa, et al. "Systemic Antibiotics Influence Periodontal Parameters and Oral Microbiota, But Not Serological Markers." Frontiers in cellular and infection microbiology vol. 11 (2021): 774665. doi: https://doi.org/10.3389/fcimb.2021.774665
Kopra E, Lahdentausta L, Pietiäinen M, Buhlin K, Mäntylä P, Hörkkö S, Persson R, Paju S, Sinisalo J, Salminen A, Pussinen PJ. Systemic Antibiotics Influence Periodontal Parameters and Oral Microbiota, But Not Serological Markers. Front Cell Infect Microbiol. 2021 Dec 24;11:774665. doi: 10.3389/fcimb.2021.774665. eCollection 2021. PMID: 35004349; PMCID: PMC8738095.
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Tryptophan Fluorescence Quenching Assays for Measuring Protein-ligand Binding Affinities: Principles and a Practical Guide.

Bio-protocol

Yammine A, Gao J, Kwan AH.
PMID: 33654778
Bio Protoc. 2019 Jun 05;9(11):e3253. doi: 10.21769/BioProtoc.3253. eCollection 2019 Jun 05.

Tryptophan fluorescence quenching is a type of fluorescence spectroscopy used for binding assays. The assay relies on the ability to quench the intrinsic fluorescence of tryptophan residues within a protein that results from changes in the local environment polarity...

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Yammine A, Gao J, Kwan AH. Tryptophan Fluorescence Quenching Assays for Measuring Protein-ligand Binding Affinities: Principles and a Practical Guide. Bio Protoc. 2019;9(11):e3253doi: 10.21769/BioProtoc.3253.
Yammine, A., Gao, J., & Kwan, A. H. (2019). Tryptophan Fluorescence Quenching Assays for Measuring Protein-ligand Binding Affinities: Principles and a Practical Guide. Bio-protocol, 9(11), e3253. https://doi.org/10.21769/BioProtoc.3253
Yammine, Anthony, et al. "Tryptophan Fluorescence Quenching Assays for Measuring Protein-ligand Binding Affinities: Principles and a Practical Guide." Bio-protocol vol. 9,11 (2019): e3253. doi: https://doi.org/10.21769/BioProtoc.3253
Yammine A, Gao J, Kwan AH. Tryptophan Fluorescence Quenching Assays for Measuring Protein-ligand Binding Affinities: Principles and a Practical Guide. Bio Protoc. 2019 Jun 05;9(11):e3253. doi: 10.21769/BioProtoc.3253. eCollection 2019 Jun 05. PMID: 33654778; PMCID: PMC7854220.
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Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery.

Frontiers in cardiovascular medicine

Nummi A, Mulari S, Stewart JA, Kivistö S, Teittinen K, Nieminen T, Lampinen M, Pätilä T, Sintonen H, Juvonen T, Kupari M, Suojaranta R, Kankuri E, Harjula A, Vento A.
PMID: 34595223
Front Cardiovasc Med. 2021 Sep 14;8:726889. doi: 10.3389/fcvm.2021.726889. eCollection 2021.

No abstract available.

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Nummi A, Mulari S, Stewart JA, et al. Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery. Front Cardiovasc Med. 2021;8:726889doi: 10.3389/fcvm.2021.726889.
Nummi, A., Mulari, S., Stewart, J. A., Kivistö, S., Teittinen, K., Nieminen, T., Lampinen, M., Pätilä, T., Sintonen, H., Juvonen, T., Kupari, M., Suojaranta, R., Kankuri, E., Harjula, A., Vento, A. (2021). Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery. Frontiers in cardiovascular medicine, 8726889. https://doi.org/10.3389/fcvm.2021.726889
Nummi, Annu, et al. "Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery." Frontiers in cardiovascular medicine vol. 8 (2021): 726889. doi: https://doi.org/10.3389/fcvm.2021.726889
Nummi A, Mulari S, Stewart JA, Kivistö S, Teittinen K, Nieminen T, Lampinen M, Pätilä T, Sintonen H, Juvonen T, Kupari M, Suojaranta R, Kankuri E, Harjula A, Vento A. Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery. Front Cardiovasc Med. 2021 Sep 14;8:726889. doi: 10.3389/fcvm.2021.726889. eCollection 2021. PMID: 34595223; PMCID: PMC8476794.
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Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology.

Virology

Heinimäki S, Lampinen V, Tamminen K, Hankaniemi MM, Malm M, Hytönen VP, Blazevic V.
PMID: 34894525
Virology. 2021 Dec 03;566:89-97. doi: 10.1016/j.virol.2021.12.001. Epub 2021 Dec 03.

Virus-like particles (VLPs) modified through different molecular technologies are employed as delivery vehicles or platforms for heterologous antigen display. We have recently created a norovirus (NoV) VLP platform, where two influenza antigens, the extracellular domain of matrix protein M2...

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Heinimäki S, Lampinen V, Tamminen K, et al. Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology. Virology. 2021;566:89-97doi: 10.1016/j.virol.2021.12.001.
Heinimäki, S., Lampinen, V., Tamminen, K., Hankaniemi, M. M., Malm, M., Hytönen, V. P., & Blazevic, V. (2021). Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology. Virology, 56689-97. https://doi.org/10.1016/j.virol.2021.12.001
Heinimäki, Suvi, et al. "Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology." Virology vol. 566 (2021): 89-97. doi: https://doi.org/10.1016/j.virol.2021.12.001
Heinimäki S, Lampinen V, Tamminen K, Hankaniemi MM, Malm M, Hytönen VP, Blazevic V. Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology. Virology. 2021 Dec 03;566:89-97. doi: 10.1016/j.virol.2021.12.001. Epub 2021 Dec 03. PMID: 34894525.
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Inflammatory biomarkers in very preterm infants during early intravenous paracetamol administration.

Early human development

Aikio O, Härmä A, Härkin P, Leskinen M, Valkama M, Saarela T, Salminen A, Hallman M.
PMID: 34536795
Early Hum Dev. 2021 Oct;161:105464. doi: 10.1016/j.earlhumdev.2021.105464. Epub 2021 Sep 07.

BACKGROUND: Paracetamol promotes early closure of patent ductus arteriosus (PDA), and it may affect inflammation after preterm birth.OBJECTIVE: The aim of this study was to evaluate the association between paracetamol treatment and serum inflammatory biomarkers in very preterm infants...

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Aikio O, Härmä A, Härkin P, et al. Inflammatory biomarkers in very preterm infants during early intravenous paracetamol administration. Early Hum Dev. 2021;161:105464doi: 10.1016/j.earlhumdev.2021.105464.
Aikio, O., Härmä, A., Härkin, P., Leskinen, M., Valkama, M., Saarela, T., Salminen, A., & Hallman, M. (2021). Inflammatory biomarkers in very preterm infants during early intravenous paracetamol administration. Early human development, 161105464. https://doi.org/10.1016/j.earlhumdev.2021.105464
Aikio, Outi, et al. "Inflammatory biomarkers in very preterm infants during early intravenous paracetamol administration." Early human development vol. 161 (2021): 105464. doi: https://doi.org/10.1016/j.earlhumdev.2021.105464
Aikio O, Härmä A, Härkin P, Leskinen M, Valkama M, Saarela T, Salminen A, Hallman M. Inflammatory biomarkers in very preterm infants during early intravenous paracetamol administration. Early Hum Dev. 2021 Oct;161:105464. doi: 10.1016/j.earlhumdev.2021.105464. Epub 2021 Sep 07. PMID: 34536795.
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Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Salminen A, Kaarniranta K, Kauppinen A.
PMID: 34476533
Inflamm Res. 2021 Dec;70(10):1043-1061. doi: 10.1007/s00011-021-01498-3. Epub 2021 Sep 02.

BACKGROUND: The insulin/IGF-1 signaling pathway has a major role in the regulation of longevity both in Caenorhabditis elegans and mammalian species, i.e., reduced activity of this pathway extends lifespan, whereas increased activity accelerates the aging process. The insulin/IGF-1 pathway...

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Salminen A, Kaarniranta K, Kauppinen A. Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases. Inflamm Res. 2021;70(10):1043-1061doi: 10.1007/s00011-021-01498-3.
Salminen, A., Kaarniranta, K., & Kauppinen, A. (2021). Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 70(10), 1043-1061. https://doi.org/10.1007/s00011-021-01498-3
Salminen, Antero, et al. "Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases." Inflammation research : official journal of the European Histamine Research Society ... [et al.] vol. 70,10 (2021): 1043-1061. doi: https://doi.org/10.1007/s00011-021-01498-3
Salminen A, Kaarniranta K, Kauppinen A. Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases. Inflamm Res. 2021 Dec;70(10):1043-1061. doi: 10.1007/s00011-021-01498-3. Epub 2021 Sep 02. PMID: 34476533; PMCID: PMC8572812.
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Malignant vestibular schwannoma with intracerebral metastasis.

British journal of neurosurgery

Salehi-Reyhani SA, Zilani G, Lammie A, Hayhurst C.
PMID: 33686895
Br J Neurosurg. 2021 Mar 09;1-4. doi: 10.1080/02688697.2021.1884650. Epub 2021 Mar 09.

BACKGROUND: Malignant change in vestibular schwannoma is rare and intracranial metastatic deposits have not been reported.CLINICAL PRESENTATION: We report the case of a 64 year old woman with a benign vestibular schwannoma who underwent translabyrinthine excision in 1996 and...

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Salehi-Reyhani SA, Zilani G, Lammie A, et al. Malignant vestibular schwannoma with intracerebral metastasis. Br J Neurosurg. 2021;1-4doi: 10.1080/02688697.2021.1884650.
Salehi-Reyhani, S. A., Zilani, G., Lammie, A., & Hayhurst, C. (2021). Malignant vestibular schwannoma with intracerebral metastasis. British journal of neurosurgery, 1-4. https://doi.org/10.1080/02688697.2021.1884650
Salehi-Reyhani, Sayedeh Ameneh, et al. "Malignant vestibular schwannoma with intracerebral metastasis." British journal of neurosurgery vol. (2021): 1-4. doi: https://doi.org/10.1080/02688697.2021.1884650
Salehi-Reyhani SA, Zilani G, Lammie A, Hayhurst C. Malignant vestibular schwannoma with intracerebral metastasis. Br J Neurosurg. 2021 Mar 09;1-4. doi: 10.1080/02688697.2021.1884650. Epub 2021 Mar 09. PMID: 33686895.
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PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples.

Bioinformatics (Oxford, England)

Häkkinen A, Zhang K, Alkodsi A, Andersson N, Pekcan Erkan E, Dai J, Kaipio K, Lamminen T, Mansuri N, Huhtinen K, Vähärautio A, Carpén O, Hynninen J, Hietanen S, Lehtonen R, Hautaniemi S.
PMID: 33720334
Bioinformatics. 2021 Mar 15; doi: 10.1093/bioinformatics/btab178. Epub 2021 Mar 15.

MOTIVATION: A major challenge in analyzing cancer patient transcriptomes is that the tumors are inherently heterogeneous and evolving. We analyzed 214 bulk RNA samples of a longitudinal, prospective ovarian cancer cohort and found that the sample composition changes systematically...

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Häkkinen A, Zhang K, Alkodsi A, et al. PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples. Bioinformatics. 2021;doi: 10.1093/bioinformatics/btab178.
Häkkinen, A., Zhang, K., Alkodsi, A., Andersson, N., Pekcan Erkan, E., Dai, J., Kaipio, K., Lamminen, T., Mansuri, N., Huhtinen, K., Vähärautio, A., Carpén, O., Hynninen, J., Hietanen, S., Lehtonen, R., & Hautaniemi, S. (2021). PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples. Bioinformatics (Oxford, England), . https://doi.org/10.1093/bioinformatics/btab178
Häkkinen, Antti, et al. "PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples." Bioinformatics (Oxford, England) vol. (2021). doi: https://doi.org/10.1093/bioinformatics/btab178
Häkkinen A, Zhang K, Alkodsi A, Andersson N, Pekcan Erkan E, Dai J, Kaipio K, Lamminen T, Mansuri N, Huhtinen K, Vähärautio A, Carpén O, Hynninen J, Hietanen S, Lehtonen R, Hautaniemi S. PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples. Bioinformatics. 2021 Mar 15; doi: 10.1093/bioinformatics/btab178. Epub 2021 Mar 15. PMID: 33720334; PMCID: PMC8479664.
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Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs.

Marine drugs

Patel PA, Bruun T, Ilina P, Mäkkylä H, Lempinen A, Yli-Kauhaluoma J, Tammela P, Kiuru PS.
PMID: 34356825
Mar Drugs. 2021 Jul 20;19(7). doi: 10.3390/md19070400.

Marine-originated spirocyclic bromotyrosines are considered as promising scaffolds for new anticancer drugs. In a continuation of our research to develop potent and more selective anticancer compounds, we synthesized a library of 32 spirocyclic clavatadine analogs by replacing the agmatine,...

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Patel PA, Bruun T, Ilina P, et al. Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs. Mar Drugs. 2021;19(7)doi: 10.3390/md19070400.
Patel, P. A., Bruun, T., Ilina, P., Mäkkylä, H., Lempinen, A., Yli-Kauhaluoma, J., Tammela, P., & Kiuru, P. S. (2021). Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs. Marine drugs, 19(7), . https://doi.org/10.3390/md19070400
Patel, Piyush A, et al. "Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs." Marine drugs vol. 19,7 (2021). doi: https://doi.org/10.3390/md19070400
Patel PA, Bruun T, Ilina P, Mäkkylä H, Lempinen A, Yli-Kauhaluoma J, Tammela P, Kiuru PS. Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs. Mar Drugs. 2021 Jul 20;19(7). doi: 10.3390/md19070400. PMID: 34356825; PMCID: PMC8305101.
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Showing 157 to 165 of 165 entries