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Showing 2257 to 2268 of 2268 entries
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Risk factors for wound-related complications after surgical stabilization of spinal metastases with a special focus on the effect of postoperative radiation therapy.

BMC surgery

Jarvers JS, Lange M, Schiemann S, Pfränger J, Heyde CE, Osterhoff G.
PMID: 34920720
BMC Surg. 2021 Dec 17;21(1):423. doi: 10.1186/s12893-021-01431-9.

BACKGROUND: Advancements in the field of oncological therapies during the last decades have led to a significantly prolonged survival of cancer patients. This has led to an increase in the incidence of spinal metastases. The purpose of this study...

Assessment of physiological barriers to nutrition following critical illness.

Clinical nutrition (Edinburgh, Scotland)

Whitehead J, Summers MJ, Louis R, Weinel LM, Lange K, Dunn B, Chapman MJ, Chapple LS.
PMID: 34861624
Clin Nutr. 2021 Nov 18;41(1):11-20. doi: 10.1016/j.clnu.2021.11.001. Epub 2021 Nov 18.

BACKGROUND & AIMS: Nutrition may be important for recovery from critical illness. Gastrointestinal dysfunction is a key barrier to nutrition delivery in the Intensive Care Unit (ICU) and metabolic rate is elevated exacerbating nutritional deficits. Whether these factors persist...

Low Carb Program Health App Within a Hospital-Based Obesity Setting: Observational Service Evaluation.

JMIR formative research

Hanson P, Summers C, Panesar A, Oduro-Donkor D, Lange M, Menon V, Barber TM.
PMID: 34449405
JMIR Form Res. 2021 Sep 23;5(9):e29110. doi: 10.2196/29110.

BACKGROUND: Obesity underlies much chronic disease. Digitalization of obesity management provides an opportunity to innovate our traditional model of health care delivery within this setting, and to transform its scalability potentially to the population level.OBJECTIVE: The objective was to...

DIPS (Dystonia Image-based Programming of Stimulation: a prospective, randomized, double-blind crossover trial).

Neurological research and practice

Lange F, Roothans J, Wichmann T, Gelbrich G, Röser C, Volkmann J, Reich M.
PMID: 34924027
Neurol Res Pract. 2021 Dec 20;3(1):65. doi: 10.1186/s42466-021-00165-6.

INTRODUCTION: Deep brain stimulation of the internal globus pallidus is an effective treatment for dystonia. However, there is a large variability in clinical outcome with up to 25% non-responders even in highly selected primary dystonia patients. In a large...

The improved clinical course of persistent tachypnea of infancy with inhaled bronchodilators and corticosteroids.

Pediatric pulmonology

Marczak H, Peradzyńska J, Seidl E, Griese M, Urbankowski T, Lange J, Bogusławski S, Krenke K.
PMID: 34520130
Pediatr Pulmonol. 2021 Dec;56(12):3952-3959. doi: 10.1002/ppul.25674. Epub 2021 Sep 21.

BACKGROUND: Persistent tachypnea of infancy (PTI) is the most common interstitial lung disease in young children. As no standardized therapeutic guidelines exist, different pharmaceuticals are used to treat PTI; inhaled corticosteroids (ICS) and bronchodilators being mostly used. This observation...

HIV testing and associated factors among female sex workers in Tanzania: approaching the first 90% target?.

AIDS care

Mizinduko M, Moen K, Pinkowski Tersbøl B, Likindikoki SL, Alexander Ishungisa M, Leyna GH, Makyao N, Leshabari MT, Ramadhani A, Wolf Meyrowitsch D, Lange T, Mmbaga EJ.
PMID: 34927487
AIDS Care. 2021 Dec 18;1-9. doi: 10.1080/09540121.2021.2014779. Epub 2021 Dec 18.

Use of HIV testing services among FSW in sub-Saharan Africa (SSA) is below the desired UNAIDS target of 90%. We estimated the prevalence and factors associated with HIV testing among FSW in Dar es Salaam, Tanzania. A respondent-driven sampling...

Interactions in clinical trials: Protocol and statistical analysis plan for an explorative study of four randomized ICU trials on use of pantoprazole, oxygenation targets, haloperidol and intravenous fluids.

Acta anaesthesiologica Scandinavica

Schjørring OL, Lange T, Krag M, Andersen-Ranberg NC, Meyhoff TS, Marker S, Klitgaard TL, Estrup S, Møller MH, Rasmussen BS, Poulsen LM, Perner A.
PMID: 34606090
Acta Anaesthesiol Scand. 2021 Oct 04; doi: 10.1111/aas.13990. Epub 2021 Oct 04.

BACKGROUND: Intensive care unit (ICU) patients receive numerous interventions, but knowledge about potential interactions between these interventions is limited. Co-enrolment in randomized clinical trials represents a unique opportunity to investigate any such interactions. We aim to assess interactions in...

Humoral Response to SARS-Cov-2 Vaccination in Liver Transplant Recipients-A Single-Center Experience.

Vaccines

Rashidi-Alavijeh J, Frey A, Passenberg M, Korth J, Zmudzinski J, Anastasiou OE, Saner FH, Jahn M, Lange CM, Willuweit K.
PMID: 34358154
Vaccines (Basel). 2021 Jul 04;9(7). doi: 10.3390/vaccines9070738.

Vaccination against SARS-CoV-2 infection is currently approved and shows favorable outcomes, but little known about antibody responses in solid organ transplant recipients, since these patients are known to have an impaired immune response upon vaccination and have not been...

Use of Polypropylene Strips for Reinforcement of the Cruroplasty in Laparoscopic Paraesophageal Hernia Repair: A Retrospective Cohort Study.

Digestive surgery

Van Den Dop LM, De Smet GHJ, Mamound A, Lange J, Wijnhoven BPL, Hueting W.
PMID: 34350869
Dig Surg. 2021;38(4):290-299. doi: 10.1159/000518182. Epub 2021 Jul 22.

INTRODUCTION: Laparoscopic paraesophageal hernia repair is an effective treatment for symptomatic paraesophageal hernias. To reduce recurrence rates, the use of prosthetics for the crural repair has been suggested. Mesh-related complications are rare but known to be disastrous. To address...

MiRNA Deregulation Distinguishes Anaplastic Thyroid Carcinoma (ATC) and Supports Upregulation of Oncogene Expression.

Cancers

Misiak D, Bauer M, Lange J, Haase J, Braun J, Lorenz K, Wickenhauser C, Hüttelmaier S.
PMID: 34885022
Cancers (Basel). 2021 Nov 24;13(23). doi: 10.3390/cancers13235913.

Anaplastic thyroid carcinoma (ATC) is the most fatal and rapidly evolving endocrine malignancy invading the head and neck region and accounts for up to 50% of thyroid cancer-associated deaths. Deregulation of the microRNA (miRNA) expression promotes thyroid carcinoma progression...

Rapid Assembly of Infection-Resistant Coatings: Screening and Identification of Antimicrobial Peptides Works in Cooperation with an Antifouling Background.

ACS applied materials & interfaces

Yu K, Alzahrani A, Khoddami S, Cheng JTJ, Mei Y, Gill A, Luo HD, Haney EF, Hilpert K, Hancock REW, Lange D, Kizhakkedathu JN.
PMID: 34328312
ACS Appl Mater Interfaces. 2021 Aug 11;13(31):36784-36799. doi: 10.1021/acsami.1c07515. Epub 2021 Jul 30.

Bacterial adhesion and the succeeding biofilm formation onto surfaces are responsible for implant- and device-associated infections. Bifunctional coatings integrating both nonfouling components and antimicrobial peptides (AMPs) are a promising approach to develop potent antibiofilm coatings. However, the current approaches...

Dimethyl Fumarate Treatment in Patients With Primary Progressive Multiple Sclerosis: A Randomized, Controlled Trial.

Neurology(R) neuroimmunology & neuroinflammation

Højsgaard Chow H, Talbot J, Lundell H, Gøbel Madsen C, Marstrand L, Lange T, Mahler MR, Buhelt S, Holm Hansen R, Blinkenberg M, Romme Christensen J, Soelberg Sørensen P, Rode von Essen M, Siebner HR, Sellebjerg F.
PMID: 34429340
Neurol Neuroimmunol Neuroinflamm. 2021 Aug 24;8(5). doi: 10.1212/NXI.0000000000001037. Print 2021 Sep.

BACKGROUND AND OBJECTIVE: To study whether dimethyl fumarate is superior to placebo in decreasing CSF concentrations of neurofilament light chain (NFL) in patients with primary progressive MS (PPMS).METHODS: In the double-blind, placebo-controlled phase 2 study dimethyl FUMArate treatment in...

Showing 2257 to 2268 of 2268 entries