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Showing 313 to 317 of 317 entries
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Racial Residential Segregation in Young Adulthood and Brain Integrity in Middle Age: Can We Learn From Small Samples?.

American journal of epidemiology

Al Hazzouri AZ, Jawadekar N, Kezios K, Caunca MR, Elfassy T, Calonico S, Kershaw KN, Yaffe K, Launer L, Elbejjani M, Grasset L, Manly J, Odden MC, Glymour MM.
PMID: 35020781
Am J Epidemiol. 2022 Jan 11; doi: 10.1093/aje/kwab297. Epub 2022 Jan 11.

Racial residential segregation is associated with multiple adverse health outcomes in Black individuals. Yet, the influence of structural racism and racial residential segregation on brain aging is less understood. In this study, we investigate the association between cumulative exposure...

Association of Intensive vs Standard Blood Pressure Control With Magnetic Resonance Imaging Biomarkers of Alzheimer Disease: Secondary Analysis of the SPRINT MIND Randomized Trial.

JAMA neurology

Nasrallah IM, Gaussoin SA, Pomponio R, Dolui S, Erus G, Wright CB, Launer LJ, Detre JA, Wolk DA, Davatzikos C, Williamson JD, Pajewski NM, Bryan RN.
PMID: 33683313
JAMA Neurol. 2021 May 01;78(5):568-577. doi: 10.1001/jamaneurol.2021.0178.

IMPORTANCE: Meta-analyses of randomized clinical trials have indicated that improved hypertension control reduces the risk for cognitive impairment and dementia. However, it is unclear to what extent pathways reflective of Alzheimer disease (AD) pathology are affected by hypertension control.OBJECTIVE:...

Medical activism.

Postgraduate medical journal

Launer J.
PMID: 34446506
Postgrad Med J. 2021 Sep;97(1151):611-612. doi: 10.1136/postgradmedj-2021-140809.

No abstract available.

Association of low-frequency and rare coding variants with information processing speed.

Translational psychiatry

Bressler J, Davies G, Smith AV, Saba Y, Bis JC, Jian X, Hayward C, Yanek L, Smith JA, Mirza SS, Wang R, Adams HHH, Becker D, Boerwinkle E, Campbell A, Cox SR, Eiriksdottir G, Fawns-Ritchie C, Gottesman RF, Grove ML, Guo X, Hofer E, Kardia SLR, Knol MJ, Koini M, Lopez OL, Marioni RE, Nyquist P, Pattie A, Polasek O, Porteous DJ, Rudan I, Satizabal CL, Schmidt H, Schmidt R, Sidney S, Simino J, Smith BH, Turner ST, van der Lee SJ, Ware EB, Whitmer RA, Yaffe K, Yang Q, Zhao W, Gudnason V, Launer LJ, Fitzpatrick AL, Psaty BM, Fornage M, Arfan Ikram M, van Duijn CM, Seshadri S, Mosley TH, Deary IJ.
PMID: 34864818
Transl Psychiatry. 2021 Dec 04;11(1):613. doi: 10.1038/s41398-021-01736-6.

Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as 67%. The Illumina HumanExome Bead Chip genotyping array was used to examine the association of rare...

Red Cell Distribution Width and Dementia Among Rural-Dwelling Older Adults: The MIND-China Study.

Journal of Alzheimer's disease : JAD

Jiang Z, Han X, Wang Y, Hou T, Cong L, Tang S, Han X, Ngandu T, Kivipelto M, Winblad B, Launer LJ, Du Y, Qiu C.
PMID: 34420964
J Alzheimers Dis. 2021;83(3):1187-1198. doi: 10.3233/JAD-210517.

BACKGROUND: Evidence has emerged that anemia is associated with dementia, but data on the relationships of red blood cell distribution width (RDW) with dementia and cognitive function in older adults are sparse.OBJECTIVE: We sought to investigate the associations of...

Showing 313 to 317 of 317 entries