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Showing 277 to 288 of 288 entries
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Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Scientific data

Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stančáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI.
PMID: 29360107
Sci Data. 2018 Jan 23;5:180002. doi: 10.1038/sdata.2018.2.

This corrects the article DOI: 10.1038/sdata.2017.179.

Nationwide Survival Benefit after Implementation of First-Line Immunotherapy for Patients with Advanced NSCLC-Real World Efficacy.

Cancers

Mouritzen MT, Carus A, Ladekarl M, Meldgaard P, Nielsen AWM, Livbjerg A, Larsen JW, Skuladottir H, Kristiansen C, Wedervang K, Schytte T, Hansen KH, Østby AC, Frank MS, Lauritsen J, Sørensen JB, Langer SW, Persson GF, Andersen JL, Frary JMC, Drivsholm LB, Vesteghem C, Christensen HS, Bjørnhart B, Pøhl M.
PMID: 34638329
Cancers (Basel). 2021 Sep 28;13(19). doi: 10.3390/cancers13194846.

Background The selection of patients with non-small cell lung cancer (NSCLC) for immune checkpoint inhibitor (ICI) treatment remains challenging. This real-world study aimed to compare the overall survival (OS) before and after the implementation of ICIs, to identify OS...

Paternity After Treatment for Testicular Germ Cell Cancer: A Danish Nationwide Population-Based Cohort Study.

Journal of the National Cancer Institute

Bandak M, Jensen A, Dehlendorff C, Lauritsen J, Kreiberg M, Wagner T, Rosenvilde J, Daugaard G.
PMID: 34180995
J Natl Cancer Inst. 2022 Jan 11;114(1):149-155. doi: 10.1093/jnci/djab130.

BACKGROUND: Testicular germ cell cancer (TC) incidence peaks during reproductive age, but knowledge on fertility after treatment is insufficient. The aim was to evaluate paternity after today's TC treatment.METHODS: Clinical data were extracted from the Danish Testicular Cancer database,...

Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine.

Current pain and headache reports

Mojica JJ, Schwenk ES, Lauritsen C, Nahas SJ.
PMID: 34894295
Curr Pain Headache Rep. 2021 Dec 11;25(12):77. doi: 10.1007/s11916-021-00992-x.

PURPOSE OF REVIEW: The purpose of this review is to discuss the available evidence and therapeutic considerations for intravenous drug therapy for refractory chronic migraine.RECENT FINDINGS: In carefully monitored settings, the inpatient administration of intravenous lidocaine and ketamine can...

The Effect of Melatonin on Incretin Hormones: Results From Experimental and Randomized Clinical Studies.

The Journal of clinical endocrinology and metabolism

Lauritzen ES, Støy J, Bæch-Laursen C, Grarup N, Jessen N, Hansen T, Møller N, Hartmann B, Holst JJ, Kampmann U.
PMID: 34265066
J Clin Endocrinol Metab. 2021 Nov 19;106(12):e5109-e5123. doi: 10.1210/clinem/dgab521.

CONTEXT: Glucose homeostasis is under circadian control through both endocrine and intracellular mechanisms, with several lines of evidence suggesting that melatonin affects glucose homeostasis.OBJECTIVE: To evaluate the acute in vivo and in situ effects of melatonin on secretion of...

Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine.

Current pain and headache reports

Mojica JJ, Schwenk ES, Lauritsen C, Nahas SJ.
PMID: 34894295
Curr Pain Headache Rep. 2021 Dec 11;25(12):77. doi: 10.1007/s11916-021-00992-x.

PURPOSE OF REVIEW: The purpose of this review is to discuss the available evidence and therapeutic considerations for intravenous drug therapy for refractory chronic migraine.RECENT FINDINGS: In carefully monitored settings, the inpatient administration of intravenous lidocaine and ketamine can...

Exploring the effects of oily fish consumption on measures of acute and long-term stress in healthy 8-9-year-old children: the FiSK Junior randomised trial.

The British journal of nutrition

Teisen MN, Vuholm S, Rantanen JM, Christensen JH, Damsgaard CT, Lauritzen L.
PMID: 33536096
Br J Nutr. 2021 Oct 28;126(8):1194-1202. doi: 10.1017/S000711452000519X. Epub 2020 Dec 28.

Long-chain n-3 PUFA (n-3 LCPUFA) are known to reduce blood pressure (BP), heart rate and vagal tone, but potential stress-mitigating effects of n-3 LCPUFA are not well investigated. We explored the effects of oily fish consumption on long-term stress...

Depletion and enrichment of phytosterols in soybean oil lipid emulsions directly associate with serum markers of cholestasis in preterm parenteral nutrition-fed pigs.

JPEN. Journal of parenteral and enteral nutrition

Guthrie G, Stoll B, Chacko S, Mohammad M, Style C, Verla M, Olutoye O, Schady D, Lauridsen C, Tataryn N, Burrin D.
PMID: 33581699
JPEN J Parenter Enteral Nutr. 2021 Feb 13; doi: 10.1002/jpen.2088. Epub 2021 Feb 13.

BACKGROUND: Clinical reports show a positive correlation between phytosterol concentrations and severity of cholestatic liver disease markers in infants during long-term administration of parenteral lipid emulsions. Establishing a causal link between phytosterols and cholestasis has been complicated by confounding...

A Mixed-Method Evaluation of a Prison Anti-doping Intervention: The Hercules Prison Program.

Frontiers in sports and active living

Sagoe D, Johnsen B, Lindblad B, Normann TAJ, Skogvoll V, Heierdal M, Lauritzen F.
PMID: 35005620
Front Sports Act Living. 2021 Dec 23;3:779218. doi: 10.3389/fspor.2021.779218. eCollection 2021.

The Norwegian Offender Mental Health and Addiction study denotes the need for physical activity and anti-doping interventions in Norwegian prisons. We developed and evaluated the efficacy of such intervention-the Hercules prison program. The program combines theoretical anti-doping lessons with...

A Simple and Cost-Effective Method for Measuring Hemolysis in Biobank Serum Specimens.

Biopreservation and biobanking

Gislefoss RE, Berge U, Lauritzen M, Langseth H, Wojewodzic MW.
PMID: 34613836
Biopreserv Biobank. 2021 Oct 05; doi: 10.1089/bio.2021.0037. Epub 2021 Oct 05.

No abstract available.

Adipose MDM2 regulates systemic insulin sensitivity.

Scientific reports

Hallenborg P, Jensen BAH, Fjære E, Petersen RK, Belmaâti MS, Rasmussen SS, Gunnarsson JP, Lauritzen P, Cheng KKY, Hermansson M, Sonne SB, Ejsing CS, Xu A, Kratchmarova I, Krüger M, Madsen L, Kristiansen K, Blagoev B.
PMID: 34750429
Sci Rep. 2021 Nov 08;11(1):21839. doi: 10.1038/s41598-021-01240-3.

The intimate association between obesity and type II diabetes urges for a deeper understanding of adipocyte function. We and others have previously delineated a role for the tumor suppressor p53 in adipocyte biology. Here, we show that mice haploinsufficient...

The Effect of Melatonin on Incretin Hormones: Results From Experimental and Randomized Clinical Studies.

The Journal of clinical endocrinology and metabolism

Lauritzen ES, Støy J, Bæch-Laursen C, Grarup N, Jessen N, Hansen T, Møller N, Hartmann B, Holst JJ, Kampmann U.
PMID: 34265066
J Clin Endocrinol Metab. 2021 Nov 19;106(12):e5109-e5123. doi: 10.1210/clinem/dgab521.

CONTEXT: Glucose homeostasis is under circadian control through both endocrine and intracellular mechanisms, with several lines of evidence suggesting that melatonin affects glucose homeostasis.OBJECTIVE: To evaluate the acute in vivo and in situ effects of melatonin on secretion of...

Showing 277 to 288 of 288 entries