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Showing 25 to 36 of 130 entries
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Epilepsy research

Flaus A, Mellerio C, Rodrigo S, Brulon V, Lebon V, Chassoux F.
PMID: 34847426
Epilepsy Res. 2021 Dec;178:106819. doi: 10.1016/j.eplepsyres.2021.106819. Epub 2021 Nov 20.

PURPOSE: Hybrid PET/MR is a promising tool in focal drug-resistant epilepsy, however the additional value for the detection of epileptogenic lesions and surgical decision-making remains to be established.METHODS: We retrospectively compared RESULTS: The location of epileptic focus was temporal...

A framework for automated gene selection in genomic applications.

Genetics in medicine : official journal of the American College of Medical Genetics

Lazo de la Vega L, Yu W, Machini K, Austin-Tse CA, Hao L, Blout Zawatsky CL, Mason-Suares H, Green RC, Rehm HL, Lebo MS.
PMID: 34113001
Genet Med. 2021 Oct;23(10):1993-1997. doi: 10.1038/s41436-021-01213-x. Epub 2021 Jun 10.

PURPOSE: An efficient framework to identify disease-associated genes is needed to evaluate genomic data for both individuals with an unknown disease etiology and those undergoing genomic screening. Here, we propose a framework for gene selection used in genomic analyses,...

Modulation of the Serotonergic Receptosome in the Treatment of Anxiety and Depression: A Narrative Review of the Experimental Evidence.

Pharmaceuticals (Basel, Switzerland)

Villas-Boas GR, Lavorato SN, Paes MM, de Carvalho PMG, Rescia VC, Cunha MS, de Magalhães-Filho MF, Ponsoni LF, de Carvalho AAV, de Lacerda RB, da S Leite L, da S Tavares-Henriques M, Lopes LAF, Oliveira LGR, Silva-Filho SE, da Silveira APS, Cuman RKN, de S Silva-Comar FM, Comar JF, do A Brasileiro L, Dos Santos JN, de Freitas WR, Leão KV, da Silva JG, Klein RC, Klein MHF, da S Ramos BH, Fernandes CKC, de L Ribas DG, Oesterreich SA.
PMID: 33673205
Pharmaceuticals (Basel). 2021 Feb 12;14(2). doi: 10.3390/ph14020148.

Serotonin (5-HT) receptors are found throughout central and peripheral nervous systems, mainly in brain regions involved in the neurobiology of anxiety and depression. 5-HT receptors are currently promising targets for discovering new drugs for treating disorders ranging from migraine...

Waning antibody response and cellular immunity 6 months after third dose SARS-Cov-2 mRNA BNT162b2 vaccine in kidney transplant recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Bertrand D, Lemée V, Laurent C, Lemoine M, Hanoy M, Le Roy F, Nezam D, Pruteanu D, Lebourg L, Grange S, Plantier JC, Boyer O, Guerrot D, Candon S.
PMID: 35007383
Am J Transplant. 2022 Jan 10; doi: 10.1111/ajt.16954. Epub 2022 Jan 10.

No abstract available.

Reduced Flow-Mediated Dilatation Is Not Related to COVID-19 Severity Three Months after Hospitalization for SARS-CoV-2 Infection.

Journal of clinical medicine

Riou M, Oulehri W, Momas C, Rouyer O, Lebourg F, Meyer A, Enache I, Pistea C, Charloux A, Marcot C, de Blay F, Collange O, Mertes M, Andrès E, Talha S, Geny B.
PMID: 33806800
J Clin Med. 2021 Mar 23;10(6). doi: 10.3390/jcm10061318.

The coronavirus disease 2019 (COVID-19) pandemic has spread rapidly worldwide, with more than two million deaths. Evidence indicates the critical role of the vascular endothelium in its pathophysiology but, like potential changes in functional vasodilation, the vascular effect of...

Identification of New Rofecoxib-Based Cyclooxygenase-2 Inhibitors: A Bioinformatics Approach.

Pharmaceuticals (Basel, Switzerland)

Leão RP, Cruz JV, da Costa GV, Cruz JN, Ferreira EFB, Silva RC, de Lima LR, Borges RS, Dos Santos GB, Santos CBR.
PMID: 32858871
Pharmaceuticals (Basel). 2020 Aug 26;13(9). doi: 10.3390/ph13090209.

The cyclooxygenase-2 receptor is a therapeutic target for planning potential drugs with anti-inflammatory activity. The selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib was selected as a pivot molecule to perform virtual ligand-based screening from six commercial databases. We performed the search...

Fibronectin-matrix sandwich-like microenvironments to manipulate cell fate.

Biomaterials science

Ballester-Beltrán J, Moratal D, Lebourg M, Salmerón-Sánchez M.
PMID: 32481864
Biomater Sci. 2014 Mar 03;2(3):381-389. doi: 10.1039/c3bm60248f. Epub 2013 Nov 25.

Conventional 2D substrates fail to represent the natural environment of cells surrounded by the 3D extracellular matrix (ECM). We have proposed sandwich-like microenvironments as a versatile tool to study cell behaviour under quasi-3D conditions. This is a system that...

Catalytic conversion of methane to methanol on Cu-SSZ-13 using N.

Chemical communications (Cambridge, England)

Ipek B, Lobo RF.
PMID: 27790665
Chem Commun (Camb). 2016 Nov 08;52(91):13401-13404. doi: 10.1039/c6cc07893a.

Direct catalytic methanol production from methane is achieved on Cu-SSZ-13 zeolite catalysts using N

Genome Sequence of Airborne Acinetobacter sp. Strain 5-2Ac02 in the Hospital Environment, Close to the Species of Acinetobacter towneri.

Genome announcements

Barbosa BG, Fernandez-García L, Gato E, López M, Blasco L, Leão RS, Albano RM, Fernández B, Cuenca FF, Pascual Á, Bou G, Marques EA, Tomás M.
PMID: 27932646
Genome Announc. 2016 Dec 08;4(6). doi: 10.1128/genomeA.01343-16.

Acinetobacter spp. are found in 53% of air colonization samples from the hospital environment. In this work, we sequenced all the genome of airborne Acinetobacter sp. strain 5-2Ac02. We found important features at the genomic level in regards to...

The authors reply.

Critical care medicine

Ridgeon EE, Young PJ, Bellomo R, Mucchetti M, Lembo R, Landoni G.
PMID: 27755082
Crit Care Med. 2016 Nov;44(11):e1143. doi: 10.1097/CCM.0000000000002045.

No abstract available.

SARS-CoV-2-specific Humoral and Cellular Immunities in Kidney Transplant Recipients and Dialyzed Patients Recovered From Severe and Nonsevere COVID-19.

Transplantation direct

Bertrand D, Hamzaoui M, Drouot L, Lamulle J, Hanoy M, Edet S, Laurent C, Lebourg L, Etienne I, Lemoine M, Le Roy F, Nezam D, Mauger E, Boyer O, Guerrot D, Candon S.
PMID: 34805494
Transplant Direct. 2021 Nov 17;7(12):e792. doi: 10.1097/TXD.0000000000001230. eCollection 2021 Dec.

Kidney transplantation and dialysis are two major risk factors for severe forms of coronavirus disease 2019 (COVID-19). The dynamics of the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in this population remain largely unknown.METHODS: We report...

News about The Journal of the Society for Gynecologic Investigation.

Journal of the Society for Gynecologic Investigation

Lobo RA.
PMID: 11750864
J Soc Gynecol Investig. 2001 Nov-Dec;8(6):317.

No abstract available.

Showing 25 to 36 of 130 entries