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Showing 25 to 36 of 150 entries
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Distinguishing Galactoside Isomers with Mass Spectrometry and Gas-Phase Infrared Spectroscopy.

Journal of the American Chemical Society

Ho JS, Gharbi A, Schindler B, Yeni O, Brédy R, Legentil L, Ferrières V, Kiessling LL, Compagnon I.
PMID: 34236183
J Am Chem Soc. 2021 Jul 21;143(28):10509-10513. doi: 10.1021/jacs.0c11919. Epub 2021 Jul 08.

Sequencing glycans is demanding due to their structural diversity. Compared to mammalian glycans, bacterial glycans pose a steeper challenge because they are constructed from a larger pool of monosaccharide building blocks, including pyranose and furanose isomers. Though mammalian glycans...

Variations of cross-sectional meniscal morphology between similar-sized menisci: implications on donor selection for meniscal allograft transplantation.

Archives of orthopaedic and trauma surgery

Unal M, Aktan C, Levent A, Cetin M, Kose O, Sarikcioglu L.
PMID: 33950275
Arch Orthop Trauma Surg. 2021 May 05; doi: 10.1007/s00402-021-03909-w. Epub 2021 May 05.

PURPOSE: This study aimed to investigate the morphological variations in the cross-sectional anatomy of the meniscus between similar-sized matched menisci.MATERIALS AND METHODS: Knee MRI of 329 patients with intact menisci were retrospectively reviewed, and the meniscal length (ML), meniscal...

Comparative transcriptome analysis at the onset of speciation in a mimetic butterfly-The Ithomiini Melinaea marsaeus.

Journal of evolutionary biology

Piron-Prunier F, Persyn E, Legeai F, McClure M, Meslin C, Robin S, Alves-Carvalho S, Mohammad A, Blugeon C, Jacquin-Joly E, Montagné N, Elias M, Gauthier J.
PMID: 34570954
J Evol Biol. 2021 Nov;34(11):1704-1721. doi: 10.1111/jeb.13940. Epub 2021 Oct 11.

Ecological speciation entails divergent selection on specific traits and ultimately on the developmental pathways responsible for these traits. Selection can act on gene sequences but also on regulatory regions responsible for gene expression. Mimetic butterflies are a relevant system...

The effect of interventions targeting gut microbiota on depressive symptoms: a systematic review and meta-analysis.

CMAJ open

Hofmeister M, Clement F, Patten S, Li J, Dowsett LE, Farkas B, Mastikhina L, Egunsola O, Diaz R, Cooke NCA, Taylor VH.
PMID: 34933877
CMAJ Open. 2021 Dec 21;9(4):E1195-E1204. doi: 10.9778/cmajo.20200283. Print 2021.

BACKGROUND: Despite their popularity, the efficacy of interventions targeting gut microbiota to improve depressive symptoms is unknown. Our objective is to summarize the effect of microbiome-targeting interventions on depressive symptoms.METHODS: We conducted a systematic review and meta-analysis. We searched...

Middle-Ear Resonance Frequency and Eustachian Tube Function in Players of Wind Instruments.

Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)

Ozer F, Ozer C, Erbek S, Ozluoglu LN.
PMID: 34412053
Folia Phoniatr Logop. 2021;73(6):586-594. doi: 10.1159/000517064. Epub 2021 Aug 19.

INTRODUCTION: The effect of the continuous forced expiration action of players of wind instruments to produce sound, on the eustachian tube functions and the middle-ear resonance frequency (RF), has not been investigated in the literature to date. The aim...

Roeperone A, a new tetraoxygenated xanthone and other compounds from the leaves of .

Natural product research

Damen F, Simo Mpetga JD, Demgne OMF, Çelik İ, Wamba BEN, Tapondjou LA, Beng VP, Levent S, Kuete V, Tene M.
PMID: 33172297
Nat Prod Res. 2020 Nov 10;1-7. doi: 10.1080/14786419.2020.1845674. Epub 2020 Nov 10.

Chemical investigation of the methanol extract from the leaves of

Conductive Highly Filled Suspensions for an Electrochemical Dispensing Approach to Pattern Full-Area Thin Metal Layers by Physical Vapour Deposition.

Scientific reports

Gensowski K, Tepner S, Schweigert S, Clement F, Kamp M, Pospischil M, Bartsch J, Stephens JC.
PMID: 32366947
Sci Rep. 2020 May 04;10(1):7409. doi: 10.1038/s41598-020-64105-1.

This paper presents a systematic approach for the development of highly filled suspensions used for an electrochemical dispensing approach. Electrochemical dispensing is an alternative structuring process to locally pattern PVD full-area thin metal layers with the goal to create...

Design, synthesis, biological activity, molecular docking, and molecular dynamics of novel benzimidazole derivatives as potential AChE/MAO-B dual inhibitors.

Archiv der Pharmazie

Osmaniye D, Evren AE, Sağlık BN, Levent S, Özkay Y, Kaplancıklı ZA.
PMID: 34931332
Arch Pharm (Weinheim). 2021 Dec 20;e2100450. doi: 10.1002/ardp.202100450. Epub 2021 Dec 20.

To develop new acetylcholinesterase (AChE)-monoamine oxidase-B (MAO-B) dual inhibitors against Alzheimer's disease, the benzimidazole ring, which has a propargyl side chain with previously proven selective MAO-B inhibitory activity, was used as the main structure. Moreover, like donepezil, it was...

Exposure-response modeling improves selection of radiation and radiosensitizer combinations.

Journal of pharmacokinetics and pharmacodynamics

Cardilin T, Almquist J, Jirstrand M, Zimmermann A, Lignet F, El Bawab S, Gabrielsson J.
PMID: 34623558
J Pharmacokinet Pharmacodyn. 2021 Oct 08; doi: 10.1007/s10928-021-09784-7. Epub 2021 Oct 08.

A central question in drug discovery is how to select drug candidates from a large number of available compounds. This analysis presents a model-based approach for comparing and ranking combinations of radiation and radiosensitizers. The approach is quantitative and...

Evaluation of Thymol-β-d-Glucopyranoside as a Potential Prebiotic Intervention to Reduce Carriage of Zoonotic Pathogens in Weaned and Feeder Pigs.

Microorganisms

Levent G, Anderson RC, Petrujkić B, Poole TL, He H, Genovese KJ, Hume ME, Beier RC, Harvey RB, Nisbet DJ.
PMID: 33923741
Microorganisms. 2021 Apr 16;9(4). doi: 10.3390/microorganisms9040860.

The gut of food-producing animals is a reservoir for foodborne pathogens. Thymol is bactericidal against foodborne pathogens but rapid absorption of thymol from the proximal gut precludes the delivery of effective concentrations to the lower gut where pathogens mainly...

Co-designing strategies to support patient partners during a scoping review and reflections on the process: a commentary.

Research involvement and engagement

McCarron TL, Clement F, Rasiah J, Moffat K, Wasylak T, Santana MJ.
PMID: 33971974
Res Involv Engagem. 2021 May 10;7(1):25. doi: 10.1186/s40900-021-00272-3.

BACKGROUND: Patient partners can be described as individuals who assume roles as active members on research teams, indicative of individuals with greater involvement, increased sharing of power, and increased responsibility than traditionally described by patient participants who are primarily...

Transcriptome Profiling of Starvation in the Peripheral Chemosensory Organs of the Crop Pest .

Insects

Poivet E, Gallot A, Montagné N, Senin P, Monsempès C, Legeai F, Jacquin-Joly E.
PMID: 34201462
Insects. 2021 Jun 23;12(7). doi: 10.3390/insects12070573.

Starvation is frequently encountered by animals under fluctuating food conditions in nature, and response to it is vital for life span. Many studies have investigated the behavioral and physiological responses to starvation. In particular, starvation is known to induce...

Showing 25 to 36 of 150 entries