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Fecal SARS-CoV-2 RNA is associated with decreased COVID-19 survival.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz O, Kwon DS.
PMID: 34245255
Clin Infect Dis. 2021 Jul 10; doi: 10.1093/cid/ciab623. Epub 2021 Jul 10.

The clinical significance of SARS CoV-2 RNA in stool remains uncertain. We found that extrapulmonary dissemination of infection to the gastrointestinal (GI) tract, assessed by the presence of SARS-CoV-2 RNA in stool, is associated with decreased COVID-19 survival. Measurement...

Engineered receptor binding domain immunogens elicit pan-sarbecovirus neutralizing antibodies outside the receptor binding motif.

bioRxiv : the preprint server for biology

Hauser BM, Sangesland M, Lam EC, Denis KJS, Feldman J, Yousif AS, Caradonna TM, Kannegieter T, Balazs AB, Lingwood D, Schmidt AG.
PMID: 33330872
bioRxiv. 2021 Jun 29; doi: 10.1101/2020.12.07.415216.

Effective countermeasures are needed against emerging coronaviruses of pandemic potential, similar to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Designing immunogens that elicit broadly neutralizing antibodies to conserved viral epitopes on the major surface glycoprotein, spike, such as the...

Showing 49 to 50 of 50 entries