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Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus Preautonomic Neurons and Correlates with Baroreflex Impairment in Rats.

Frontiers in physiology

De Melo VU, Saldanha RR, Dos Santos CR, De Campos Cruz J, Lira VA, Santana-Filho VJ, Michelini LC.
PMID: 27790154
Front Physiol. 2016 Oct 13;7:461. doi: 10.3389/fphys.2016.00461. eCollection 2016.

The prevalence of cardiovascular diseases including hypertension increases dramatically in women after menopause, however the mechanisms involved remain incompletely understood. Oxytocinergic (OTergic) neurons are largely present within the paraventricular nucleus of the hypothalamus (PVN). Several studies have shown that...

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De Melo VU, Saldanha RR, Dos Santos CR, et al. Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus Preautonomic Neurons and Correlates with Baroreflex Impairment in Rats. Front Physiol. 2016;7:461doi: 10.3389/fphys.2016.00461.
De Melo, V. U., Saldanha, R. R., Dos Santos, C. R., De Campos Cruz, J., Lira, V. A., Santana-Filho, V. J., & Michelini, L. C. (2016). Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus Preautonomic Neurons and Correlates with Baroreflex Impairment in Rats. Frontiers in physiology, 7461. https://doi.org/10.3389/fphys.2016.00461
De Melo, Vitor U, et al. "Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus Preautonomic Neurons and Correlates with Baroreflex Impairment in Rats." Frontiers in physiology vol. 7 (2016): 461. doi: https://doi.org/10.3389/fphys.2016.00461
De Melo VU, Saldanha RR, Dos Santos CR, De Campos Cruz J, Lira VA, Santana-Filho VJ, Michelini LC. Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus Preautonomic Neurons and Correlates with Baroreflex Impairment in Rats. Front Physiol. 2016 Oct 13;7:461. doi: 10.3389/fphys.2016.00461. eCollection 2016. PMID: 27790154; PMCID: PMC5063006.
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Levels of Folate and Vitamin B12, and Genetic Polymorphisms Involved in One-Carbon Metabolism May Increase the Risk of Cervical Cytological Abnormalities.

Nutrition and cancer

Silva NNT, Santos ACS, Brito MFDS, Peixoto do Vale DBA, Carneiro CM, Lima AA.
PMID: 34963390
Nutr Cancer. 2021 Dec 28;1-10. doi: 10.1080/01635581.2021.2022723. Epub 2021 Dec 28.

To analyze the association of cervical cytological abnormalities with genetic polymorphisms of enzymes involved in folate metabolism, and the effect of micronutrients on association of polymorphisms with cervical carcinogenesis. Our samples were divided in Control (120 women with normal...

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Silva NNT, Santos ACS, Brito MFDS, et al. Levels of Folate and Vitamin B12, and Genetic Polymorphisms Involved in One-Carbon Metabolism May Increase the Risk of Cervical Cytological Abnormalities. Nutr Cancer. 2021;1-10doi: 10.1080/01635581.2021.2022723.
Silva, N. N. T., Santos, A. C. S., Brito, M. F. D. S., Peixoto do Vale, D. B. A., Carneiro, C. M., & Lima, A. A. (2021). Levels of Folate and Vitamin B12, and Genetic Polymorphisms Involved in One-Carbon Metabolism May Increase the Risk of Cervical Cytological Abnormalities. Nutrition and cancer, 1-10. https://doi.org/10.1080/01635581.2021.2022723
Silva, Nayara Nascimento Toledo, et al. "Levels of Folate and Vitamin B12, and Genetic Polymorphisms Involved in One-Carbon Metabolism May Increase the Risk of Cervical Cytological Abnormalities." Nutrition and cancer vol. (2021): 1-10. doi: https://doi.org/10.1080/01635581.2021.2022723
Silva NNT, Santos ACS, Brito MFDS, Peixoto do Vale DBA, Carneiro CM, Lima AA. Levels of Folate and Vitamin B12, and Genetic Polymorphisms Involved in One-Carbon Metabolism May Increase the Risk of Cervical Cytological Abnormalities. Nutr Cancer. 2021 Dec 28;1-10. doi: 10.1080/01635581.2021.2022723. Epub 2021 Dec 28. PMID: 34963390.
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Protein-bound polyphenols create "ghost" band artifacts during chemiluminescence-based antigen detection.

F1000Research

Plundrich N, Lila MA, Foegeding E, Laster S.
PMID: 28721200
F1000Res. 2017 Mar 13;6:254. doi: 10.12688/f1000research.10622.1. eCollection 2017.

Antigen detection during Western blotting commonly utilizes a horseradish peroxidase-coupled secondary antibody and enhanced chemiluminescent substrate. We utilized this technique to examine the impact of green tea-derived polyphenols on the binding of egg white protein-specific IgE antibodies from allergic...

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Plundrich N, Lila MA, Foegeding E, et al. Protein-bound polyphenols create "ghost" band artifacts during chemiluminescence-based antigen detection. F1000Res. 2017;6:254doi: 10.12688/f1000research.10622.1.
Plundrich, N., Lila, M. A., Foegeding, E., & Laster, S. (2017). Protein-bound polyphenols create "ghost" band artifacts during chemiluminescence-based antigen detection. F1000Research, 6254. https://doi.org/10.12688/f1000research.10622.1
Plundrich, Nathalie, et al. "Protein-bound polyphenols create "ghost" band artifacts during chemiluminescence-based antigen detection." F1000Research vol. 6 (2017): 254. doi: https://doi.org/10.12688/f1000research.10622.1
Plundrich N, Lila MA, Foegeding E, Laster S. Protein-bound polyphenols create "ghost" band artifacts during chemiluminescence-based antigen detection. F1000Res. 2017 Mar 13;6:254. doi: 10.12688/f1000research.10622.1. eCollection 2017. PMID: 28721200; PMCID: PMC5497812.
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Legume-rhizobia signal exchange: promiscuity and environmental effects.

Frontiers in microbiology

Lira MA, Nascimento LR, Fracetto GG.
PMID: 26441880
Front Microbiol. 2015 Sep 08;6:945. doi: 10.3389/fmicb.2015.00945. eCollection 2015.

Although signal exchange between legumes and their rhizobia is among the best-known examples of this biological process, most of the more characterized data comes from just a few legume species and environmental stresses. Although a relative wealth of information...

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Lira MA, Nascimento LR, Fracetto GG. Legume-rhizobia signal exchange: promiscuity and environmental effects. Front Microbiol. 2015;6:945doi: 10.3389/fmicb.2015.00945.
Lira, M. A., Nascimento, L. R., & Fracetto, G. G. (2015). Legume-rhizobia signal exchange: promiscuity and environmental effects. Frontiers in microbiology, 6945. https://doi.org/10.3389/fmicb.2015.00945
Lira, Mario A, et al. "Legume-rhizobia signal exchange: promiscuity and environmental effects." Frontiers in microbiology vol. 6 (2015): 945. doi: https://doi.org/10.3389/fmicb.2015.00945
Lira MA, Nascimento LR, Fracetto GG. Legume-rhizobia signal exchange: promiscuity and environmental effects. Front Microbiol. 2015 Sep 08;6:945. doi: 10.3389/fmicb.2015.00945. eCollection 2015. PMID: 26441880; PMCID: PMC4561803.
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Accurate monitoring of intravascular fluid volume: A novel application of intrathoracic impedance measures for the guidance of volume reduction therapy.

International journal of cardiology. Heart & vasculature

Lara BA, Qu F, Heist EK, Pavri BB, Van Bakel AB, Herre JM, Binkley PF.
PMID: 28785678
Int J Cardiol Heart Vasc. 2015 May 15;8:47-51. doi: 10.1016/j.ijcha.2015.05.003. eCollection 2015 Sep 01.

BACKGROUND: A significant proportion of patients admitted for acute decompensated heart failure (ADHF) that undergo volume reduction therapy are discharged with unchanged or increased bodyweight suggesting that the endpoints for these therapies are not optimally defined. We aimed to...

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Lara BA, Qu F, Heist EK, et al. Accurate monitoring of intravascular fluid volume: A novel application of intrathoracic impedance measures for the guidance of volume reduction therapy. Int J Cardiol Heart Vasc. 2015;8:47-51doi: 10.1016/j.ijcha.2015.05.003.
Lara, B. A., Qu, F., Heist, E. K., Pavri, B. B., Van Bakel, A. B., Herre, J. M., & Binkley, P. F. (2015). Accurate monitoring of intravascular fluid volume: A novel application of intrathoracic impedance measures for the guidance of volume reduction therapy. International journal of cardiology. Heart & vasculature, 847-51. https://doi.org/10.1016/j.ijcha.2015.05.003
Lara, Barbara A, et al. "Accurate monitoring of intravascular fluid volume: A novel application of intrathoracic impedance measures for the guidance of volume reduction therapy." International journal of cardiology. Heart & vasculature vol. 8 (2015): 47-51. doi: https://doi.org/10.1016/j.ijcha.2015.05.003
Lara BA, Qu F, Heist EK, Pavri BB, Van Bakel AB, Herre JM, Binkley PF. Accurate monitoring of intravascular fluid volume: A novel application of intrathoracic impedance measures for the guidance of volume reduction therapy. Int J Cardiol Heart Vasc. 2015 May 15;8:47-51. doi: 10.1016/j.ijcha.2015.05.003. eCollection 2015 Sep 01. PMID: 28785678; PMCID: PMC5497263.
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Tomato UDP-Glucose Sterol Glycosyltransferases: A Family of Developmental and Stress Regulated Genes that Encode Cytosolic and Membrane-Associated Forms of the Enzyme.

Frontiers in plant science

Ramirez-Estrada K, Castillo N, Lara JA, Arró M, Boronat A, Ferrer A, Altabella T.
PMID: 28649260
Front Plant Sci. 2017 Jun 09;8:984. doi: 10.3389/fpls.2017.00984. eCollection 2017.

Sterol glycosyltransferases (SGTs) catalyze the glycosylation of the free hydroxyl group at C-3 position of sterols to produce sterol glycosides. Glycosylated sterols and free sterols are primarily located in cell membranes where in combination with other membrane-bound lipids play...

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Ramirez-Estrada K, Castillo N, Lara JA, et al. Tomato UDP-Glucose Sterol Glycosyltransferases: A Family of Developmental and Stress Regulated Genes that Encode Cytosolic and Membrane-Associated Forms of the Enzyme. Front Plant Sci. 2017;8:984doi: 10.3389/fpls.2017.00984.
Ramirez-Estrada, K., Castillo, N., Lara, J. A., Arró, M., Boronat, A., Ferrer, A., & Altabella, T. (2017). Tomato UDP-Glucose Sterol Glycosyltransferases: A Family of Developmental and Stress Regulated Genes that Encode Cytosolic and Membrane-Associated Forms of the Enzyme. Frontiers in plant science, 8984. https://doi.org/10.3389/fpls.2017.00984
Ramirez-Estrada, Karla, et al. "Tomato UDP-Glucose Sterol Glycosyltransferases: A Family of Developmental and Stress Regulated Genes that Encode Cytosolic and Membrane-Associated Forms of the Enzyme." Frontiers in plant science vol. 8 (2017): 984. doi: https://doi.org/10.3389/fpls.2017.00984
Ramirez-Estrada K, Castillo N, Lara JA, Arró M, Boronat A, Ferrer A, Altabella T. Tomato UDP-Glucose Sterol Glycosyltransferases: A Family of Developmental and Stress Regulated Genes that Encode Cytosolic and Membrane-Associated Forms of the Enzyme. Front Plant Sci. 2017 Jun 09;8:984. doi: 10.3389/fpls.2017.00984. eCollection 2017. PMID: 28649260; PMCID: PMC5465953.
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ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue.

Cell reports

Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L.
PMID: 34788615
Cell Rep. 2021 Nov 16;37(7):110003. doi: 10.1016/j.celrep.2021.110003.

Brown adipose tissue (BAT) thermogenic activity is tightly regulated by cellular redox status, but the underlying molecular mechanisms are incompletely understood. Protein S-nitrosylation, the nitric-oxide-mediated cysteine thiol protein modification, plays important roles in cellular redox regulation. Here we show...

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Sebag SC, Zhang Z, Qian Q, et al. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021;37(7):110003doi: 10.1016/j.celrep.2021.110003.
Sebag, S. C., Zhang, Z., Qian, Q., Li, M., Zhu, Z., Harata, M., Li, W., Zingman, L. V., Liu, L., Lira, V. A., Potthoff, M. J., Bartelt, A., & Yang, L. (2021). ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell reports, 37(7), 110003. https://doi.org/10.1016/j.celrep.2021.110003
Sebag, Sara C, et al. "ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue." Cell reports vol. 37,7 (2021): 110003. doi: https://doi.org/10.1016/j.celrep.2021.110003
Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021 Nov 16;37(7):110003. doi: 10.1016/j.celrep.2021.110003. PMID: 34788615; PMCID: PMC8640996.
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Pea protein isolate characteristics modulate functional properties of pea protein-cranberry polyphenol particles.

Food science & nutrition

Strauch RC, Lila MA.
PMID: 34262733
Food Sci Nutr. 2021 May 24;9(7):3740-3751. doi: 10.1002/fsn3.2335. eCollection 2021 Jul.

Plant polyphenols have a natural binding affinity for proteins, and their interaction can be exploited to form diverse aggregate particles. Protein-polyphenol particles utilized as food ingredients allow consumers to incorporate more health-benefiting plant bioactives into their diets. The functional...

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Strauch RC, Lila MA. Pea protein isolate characteristics modulate functional properties of pea protein-cranberry polyphenol particles. Food Sci Nutr. 2021;9(7):3740-3751doi: 10.1002/fsn3.2335.
Strauch, R. C., & Lila, M. A. (2021). Pea protein isolate characteristics modulate functional properties of pea protein-cranberry polyphenol particles. Food science & nutrition, 9(7), 3740-3751. https://doi.org/10.1002/fsn3.2335
Strauch, Renee Cilliers, and Lila, Mary Ann. "Pea protein isolate characteristics modulate functional properties of pea protein-cranberry polyphenol particles." Food science & nutrition vol. 9,7 (2021): 3740-3751. doi: https://doi.org/10.1002/fsn3.2335
Strauch RC, Lila MA. Pea protein isolate characteristics modulate functional properties of pea protein-cranberry polyphenol particles. Food Sci Nutr. 2021 May 24;9(7):3740-3751. doi: 10.1002/fsn3.2335. eCollection 2021 Jul. PMID: 34262733; PMCID: PMC8269610.
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Coping with COVID-19 Prolonged and Cumulative Stressors: the Case Example of Egypt.

International journal of mental health and addiction

Kira IA, Shuwiekh HAM, Ahmed SAE, Ebada EE, Tantawy SF, Waheep NN, Ashby JS.
PMID: 35035314
Int J Ment Health Addict. 2022 Jan 08;1-22. doi: 10.1007/s11469-021-00712-x. Epub 2022 Jan 08.

The current study aimed to explore how COVID-19-traumatized populations cope using a coping model based on wills to exist, live, and survive (WTELS) that leads to positive coping and posttraumatic growth (PTG). We used data from 11 Arab countries...

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Kira IA, Shuwiekh HAM, Ahmed SAE, et al. Coping with COVID-19 Prolonged and Cumulative Stressors: the Case Example of Egypt. Int J Ment Health Addict. 2022;1-22doi: 10.1007/s11469-021-00712-x.
Kira, I. A., Shuwiekh, H. A. M., Ahmed, S. A. E., Ebada, E. E., Tantawy, S. F., Waheep, N. N., & Ashby, J. S. (2022). Coping with COVID-19 Prolonged and Cumulative Stressors: the Case Example of Egypt. International journal of mental health and addiction, 1-22. https://doi.org/10.1007/s11469-021-00712-x
Kira, Ibrahim A, et al. "Coping with COVID-19 Prolonged and Cumulative Stressors: the Case Example of Egypt." International journal of mental health and addiction vol. (2022): 1-22. doi: https://doi.org/10.1007/s11469-021-00712-x
Kira IA, Shuwiekh HAM, Ahmed SAE, Ebada EE, Tantawy SF, Waheep NN, Ashby JS. Coping with COVID-19 Prolonged and Cumulative Stressors: the Case Example of Egypt. Int J Ment Health Addict. 2022 Jan 08;1-22. doi: 10.1007/s11469-021-00712-x. Epub 2022 Jan 08. PMID: 35035314; PMCID: PMC8741582.
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ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue.

Cell reports

Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L.
PMID: 34788615
Cell Rep. 2021 Nov 16;37(7):110003. doi: 10.1016/j.celrep.2021.110003.

Brown adipose tissue (BAT) thermogenic activity is tightly regulated by cellular redox status, but the underlying molecular mechanisms are incompletely understood. Protein S-nitrosylation, the nitric-oxide-mediated cysteine thiol protein modification, plays important roles in cellular redox regulation. Here we show...

Cite
Sebag SC, Zhang Z, Qian Q, et al. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021;37(7):110003doi: 10.1016/j.celrep.2021.110003.
Sebag, S. C., Zhang, Z., Qian, Q., Li, M., Zhu, Z., Harata, M., Li, W., Zingman, L. V., Liu, L., Lira, V. A., Potthoff, M. J., Bartelt, A., & Yang, L. (2021). ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell reports, 37(7), 110003. https://doi.org/10.1016/j.celrep.2021.110003
Sebag, Sara C, et al. "ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue." Cell reports vol. 37,7 (2021): 110003. doi: https://doi.org/10.1016/j.celrep.2021.110003
Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021 Nov 16;37(7):110003. doi: 10.1016/j.celrep.2021.110003. PMID: 34788615; PMCID: PMC8640996.
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The association of WTELS as a master motivator with higher executive functioning and better mental health.

Current psychology (New Brunswick, N.J.)

Kira IA, Ayna YE, Shuwiekh HAM, Ashby JS.
PMID: 34276169
Curr Psychol. 2021 Jul 10;1-12. doi: 10.1007/s12144-021-02078-8. Epub 2021 Jul 10.

The goal is to test the validity of the "Will to exist-live and survive (WTELS) as a master motivator that activates executive functions. A sample of 262 adults administered different measures that included WTELS and executive functions. We conducted...

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Kira IA, Ayna YE, Shuwiekh HAM, et al. The association of WTELS as a master motivator with higher executive functioning and better mental health. Curr Psychol. 2021;1-12doi: 10.1007/s12144-021-02078-8.
Kira, I. A., Ayna, Y. E., Shuwiekh, H. A. M., & Ashby, J. S. (2021). The association of WTELS as a master motivator with higher executive functioning and better mental health. Current psychology (New Brunswick, N.J.), 1-12. https://doi.org/10.1007/s12144-021-02078-8
Kira, Ibrahim A, et al. "The association of WTELS as a master motivator with higher executive functioning and better mental health." Current psychology (New Brunswick, N.J.) vol. (2021): 1-12. doi: https://doi.org/10.1007/s12144-021-02078-8
Kira IA, Ayna YE, Shuwiekh HAM, Ashby JS. The association of WTELS as a master motivator with higher executive functioning and better mental health. Curr Psychol. 2021 Jul 10;1-12. doi: 10.1007/s12144-021-02078-8. Epub 2021 Jul 10. PMID: 34276169; PMCID: PMC8272615.
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The berry health tool chest - an evidence map and interactive resource.

Nutrition reviews

Kay KL, Strauch RC, Granillo CD, Bame MW, Xiong J, Mast AC, Burton-Freeman B, Kay CD, Lila MA.
PMID: 33837434
Nutr Rev. 2021 Dec 08;80(1):68-77. doi: 10.1093/nutrit/nuab011.

Berry consumption is linked to diverse health benefits, but numerous questions remain regarding mechanism of action, dose efficacy, and optimal duration and frequency of intake. Addressing these outstanding questions requires an organized assessment of current research, to inform future...

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Kay KL, Strauch RC, Granillo CD, et al. The berry health tool chest - an evidence map and interactive resource. Nutr Rev. 2021;80(1):68-77doi: 10.1093/nutrit/nuab011.
Kay, K. L., Strauch, R. C., Granillo, C. D., Bame, M. W., Xiong, J., Mast, A. C., Burton-Freeman, B., Kay, C. D., & Lila, M. A. (2021). The berry health tool chest - an evidence map and interactive resource. Nutrition reviews, 80(1), 68-77. https://doi.org/10.1093/nutrit/nuab011
Kay, Kristine L, et al. "The berry health tool chest - an evidence map and interactive resource." Nutrition reviews vol. 80,1 (2021): 68-77. doi: https://doi.org/10.1093/nutrit/nuab011
Kay KL, Strauch RC, Granillo CD, Bame MW, Xiong J, Mast AC, Burton-Freeman B, Kay CD, Lila MA. The berry health tool chest - an evidence map and interactive resource. Nutr Rev. 2021 Dec 08;80(1):68-77. doi: 10.1093/nutrit/nuab011. PMID: 33837434.
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