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Showing 6805 to 6814 of 6814 entries
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Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans.

Proceedings of the National Academy of Sciences of the United States of America

Lo TH, Chen HL, Yao CI, Weng IC, Li CS, Huang CC, Chen NJ, Lin CH, Liu FT.
PMID: 34301890
Proc Natl Acad Sci U S A. 2021 Jul 27;118(30). doi: 10.1073/pnas.2026246118.

Cytosolic lipopolysaccharides (LPSs) bind directly to caspase-4/5/11 through their lipid A moiety, inducing inflammatory caspase oligomerization and activation, which is identified as the noncanonical inflammasome pathway. Galectins, β-galactoside-binding proteins, bind to various gram-negative bacterial LPS, which display β-galactoside-containing polysaccharide...

Age-Stratified Risk of Dementia in Parkinson's Disease: A Nationwide, Population-Based, Retrospective Cohort Study in Taiwan.

Frontiers in neurology

Chang TY, Yang CP, Chen YH, Lin CH, Chang MH.
PMID: 35002917
Front Neurol. 2021 Dec 24;12:748096. doi: 10.3389/fneur.2021.748096. eCollection 2021.

No abstract available.

Baicalin triggers apoptosis, inhibits migration, and enhances anti-tumor immunity in colorectal cancer via TLR4/NF-κB signaling pathway.

Journal of food biochemistry

Song L, Zhu S, Liu C, Zhang Q, Liang X.
PMID: 33742464
J Food Biochem. 2021 Mar 20;e13703. doi: 10.1111/jfbc.13703. Epub 2021 Mar 20.

Aberrant activation of the nuclear factor-kappa B (NF-κB) signaling pathway is closely implicated in colorectal cancer (CRC) growth, metastasis, and immune escape. In the present study, we reported natural derived compound of baicalin (BA), an efficient inhibitor of NF-κB,...

Dynamic Nutrient Signaling Networks in Plants.

Annual review of cell and developmental biology

Li L, Liu KH, Sheen J.
PMID: 34351784
Annu Rev Cell Dev Biol. 2021 Oct 06;37:341-367. doi: 10.1146/annurev-cellbio-010521-015047. Epub 2021 Aug 05.

Nutrients are vital to life through intertwined sensing, signaling, and metabolic processes. Emerging research focuses on how distinct nutrient signaling networks integrate and coordinate gene expression, metabolism, growth, and survival. We review the multifaceted roles of sugars, nitrate, and...

Efficacy and Safety of Pramipexole Sustained Release versus Immediate Release Formulation for Nocturnal Symptoms in Chinese Patients with Advanced Parkinson's Disease: A Pilot Study.

Parkinson's disease

Zhou H, Li S, Yu H, Sun S, Wan X, Zhu X, Liu CF, Chen L, Xiang W, Sun Y, Chen H, Chen S.
PMID: 33763199
Parkinsons Dis. 2021 Mar 03;2021:8834950. doi: 10.1155/2021/8834950. eCollection 2021.

OBJECTIVE: To explore the efficacy and safety of pramipexole sustained release (SR) versus pramipexole immediate release (IR) in treating nocturnal symptoms in levodopa-treated Chinese patients with advanced Parkinson's disease (PD) and sleep disturbances.METHOD: SUSTAIN was an open-label, randomised, active-controlled...

Cisd2 slows down liver aging and attenuates age-related metabolic dysfunction in male mice.

Aging cell

Huang YL, Shen ZQ, Huang CH, Lin CH, Tsai TF.
PMID: 34811857
Aging Cell. 2021 Dec;20(12):e13523. doi: 10.1111/acel.13523. Epub 2021 Nov 22.

The liver plays a pivotal role in mammalian aging. However, the mechanisms underlying liver aging remain unclear. Cisd2 is a pro-longevity gene in mice. Cisd2 mediates lifespan and healthspan via regulation of calcium homeostasis and mitochondrial functioning. Intriguingly, the...

Gradient of Risk and Associations With Cardiovascular Efficacy of Ertugliflozin by Measures of Kidney Function: Observations From VERTIS CV.

Circulation

Cherney DZI, McGuire DK, Charbonnel B, Cosentino F, Pratley R, Dagogo-Jack S, Frederich R, Maldonado M, Liu J, Pong A, Liu CC, Cannon CP.
PMID: 33186063
Circulation. 2021 Feb 09;143(6):602-605. doi: 10.1161/CIRCULATIONAHA.120.051901. Epub 2020 Nov 13.

No abstract available.

Correction to: Higher HbA1c may reduce axial length elongation in myopic children: a comparison cohort study.

Acta diabetologica

Liu CF, Chen SC, Chen KJ, Liu L, Chen YP, Kang EY, Liu PK, Yeung L, Wu WC, Lai CC, Lo FS, Wang NK.
PMID: 33846864
Acta Diabetol. 2021 Jun;58(6):787. doi: 10.1007/s00592-021-01695-w.

No abstract available.

[Review of clinical research in acupuncture and moxibustion from 2010 to 2020 and future prospects].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion

Yan SY, Xiong ZY, Liu XY, Liu CZ, Liu BY.
PMID: 35025168
Zhongguo Zhen Jiu. 2022 Jan 12;42(1):116-8. doi: 10.13703/j.0255-2930.20210331-0008.

The progress of Chinese clinical research on acupuncture and moxibustion in recent 10 years was reviewed and analyzed, and corresponding suggestions were put forward for the current problems. In the past 10 years, Chinese clinical research on acupuncture and...

Immigration, Race and Higher Education Outcomes.

Tai RH, Liu CQ, Fan XT.
UIID-AD: 536
2009;92-112.

No abstract available.

Showing 6805 to 6814 of 6814 entries