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Development and Validation of a Deep Learning Model for Earlier Detection of Cognitive Decline From Clinical Notes in Electronic Health Records.

JAMA network open

Wang L, Laurentiev J, Yang J, Lo YC, Amariglio RE, Blacker D, Sperling RA, Marshall GA, Zhou L.
PMID: 34792589
JAMA Netw Open. 2021 Nov 01;4(11):e2135174. doi: 10.1001/jamanetworkopen.2021.35174.

IMPORTANCE: Detecting cognitive decline earlier among older adults can facilitate enrollment in clinical trials and early interventions. Clinical notes in longitudinal electronic health records (EHRs) provide opportunities to detect cognitive decline earlier than it is noted in structured EHR...

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Wang L, Laurentiev J, Yang J, et al. Development and Validation of a Deep Learning Model for Earlier Detection of Cognitive Decline From Clinical Notes in Electronic Health Records. JAMA Netw Open. 2021;4(11):e2135174doi: 10.1001/jamanetworkopen.2021.35174.
Wang, L., Laurentiev, J., Yang, J., Lo, Y. C., Amariglio, R. E., Blacker, D., Sperling, R. A., Marshall, G. A., & Zhou, L. (2021). Development and Validation of a Deep Learning Model for Earlier Detection of Cognitive Decline From Clinical Notes in Electronic Health Records. JAMA network open, 4(11), e2135174. https://doi.org/10.1001/jamanetworkopen.2021.35174
Wang, Liqin, et al. "Development and Validation of a Deep Learning Model for Earlier Detection of Cognitive Decline From Clinical Notes in Electronic Health Records." JAMA network open vol. 4,11 (2021): e2135174. doi: https://doi.org/10.1001/jamanetworkopen.2021.35174
Wang L, Laurentiev J, Yang J, Lo YC, Amariglio RE, Blacker D, Sperling RA, Marshall GA, Zhou L. Development and Validation of a Deep Learning Model for Earlier Detection of Cognitive Decline From Clinical Notes in Electronic Health Records. JAMA Netw Open. 2021 Nov 01;4(11):e2135174. doi: 10.1001/jamanetworkopen.2021.35174. PMID: 34792589; PMCID: PMC8603078.
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Persistence, Reward Dependence, and Sensitivity to Reward Are Associated With Unexpected Salience Response in Girls but Not in Adult Women: Implications for Psychiatric Vulnerabilities.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Frank GKW, Shott ME, Sternheim LC, Swindle S, Pryor TL.
PMID: 33872764
Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Apr 17; doi: 10.1016/j.bpsc.2021.04.005. Epub 2021 Apr 17.

BACKGROUND: Adolescence is a critical period for the development of not only personality but also psychopathology. These processes may be specific to sex, and brain reward circuits may have a role. Here, we studied how reward processing and temperament...

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Frank GKW, Shott ME, Sternheim LC, et al. Persistence, Reward Dependence, and Sensitivity to Reward Are Associated With Unexpected Salience Response in Girls but Not in Adult Women: Implications for Psychiatric Vulnerabilities. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021;doi: 10.1016/j.bpsc.2021.04.005.
Frank, G. K. W., Shott, M. E., Sternheim, L. C., Swindle, S., & Pryor, T. L. (2021). Persistence, Reward Dependence, and Sensitivity to Reward Are Associated With Unexpected Salience Response in Girls but Not in Adult Women: Implications for Psychiatric Vulnerabilities. Biological psychiatry. Cognitive neuroscience and neuroimaging, . https://doi.org/10.1016/j.bpsc.2021.04.005
Frank, Guido K W, et al. "Persistence, Reward Dependence, and Sensitivity to Reward Are Associated With Unexpected Salience Response in Girls but Not in Adult Women: Implications for Psychiatric Vulnerabilities." Biological psychiatry. Cognitive neuroscience and neuroimaging vol. (2021). doi: https://doi.org/10.1016/j.bpsc.2021.04.005
Frank GKW, Shott ME, Sternheim LC, Swindle S, Pryor TL. Persistence, Reward Dependence, and Sensitivity to Reward Are Associated With Unexpected Salience Response in Girls but Not in Adult Women: Implications for Psychiatric Vulnerabilities. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Apr 17; doi: 10.1016/j.bpsc.2021.04.005. Epub 2021 Apr 17. PMID: 33872764.
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A cluster of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation.

Transplant infectious disease : an official journal of the Transplantation Society

Hosoi H, Murata S, Suzuki T, Li TC, Hatanaka K, Tanaka-Taya K, Mushino T, Kuriyama K, Tamura S, Hanaoka N, Sonoki T.
PMID: 34546601
Transpl Infect Dis. 2021 Sep 21;e13736. doi: 10.1111/tid.13736. Epub 2021 Sep 21.

BACKGROUND: BK polyomavirus (BKV) can cause hemorrhagic cystitis (HC) in immunocompromised patients after hematopoietic stem cell transplantation (HSCT). It remains unclear whether nosocomial BKV infections occur. During a 9-month period, an increase in BKV-associated HC (BKV-HC) cases was observed...

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Hosoi H, Murata S, Suzuki T, et al. A cluster of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis. 2021;e13736doi: 10.1111/tid.13736.
Hosoi, H., Murata, S., Suzuki, T., Li, T. C., Hatanaka, K., Tanaka-Taya, K., Mushino, T., Kuriyama, K., Tamura, S., Hanaoka, N., & Sonoki, T. (2021). A cluster of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Transplant infectious disease : an official journal of the Transplantation Society, e13736. https://doi.org/10.1111/tid.13736
Hosoi, Hiroki, et al. "A cluster of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation." Transplant infectious disease : an official journal of the Transplantation Society vol. (2021): e13736. doi: https://doi.org/10.1111/tid.13736
Hosoi H, Murata S, Suzuki T, Li TC, Hatanaka K, Tanaka-Taya K, Mushino T, Kuriyama K, Tamura S, Hanaoka N, Sonoki T. A cluster of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis. 2021 Sep 21;e13736. doi: 10.1111/tid.13736. Epub 2021 Sep 21. PMID: 34546601.
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Frequent occurrence of respiratory symptoms in children is associated with exposure to air pollution, land use types, and parental mental health in the Greater Taipei area.

Environmental research

Zou ML, Jiang CB, Chen YH, Wu CD, Candice Lung SC, Chien LC, Kallawicha K, Lo YC, Chao HJ.
PMID: 34932981
Environ Res. 2021 Dec 18;206:112567. doi: 10.1016/j.envres.2021.112567. Epub 2021 Dec 18.

Although studies have investigated the individual effects of air pollution, land use types, and parental mental health on children's respiratory health, few studies have examined the effects of these risk factors simultaneously in children aged

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Zou ML, Jiang CB, Chen YH, et al. Frequent occurrence of respiratory symptoms in children is associated with exposure to air pollution, land use types, and parental mental health in the Greater Taipei area. Environ Res. 2021;206:112567doi: 10.1016/j.envres.2021.112567.
Zou, M. L., Jiang, C. B., Chen, Y. H., Wu, C. D., Candice Lung, S. C., Chien, L. C., Kallawicha, K., Lo, Y. C., & Chao, H. J. (2021). Frequent occurrence of respiratory symptoms in children is associated with exposure to air pollution, land use types, and parental mental health in the Greater Taipei area. Environmental research, 206112567. https://doi.org/10.1016/j.envres.2021.112567
Zou, Ming-Lun, et al. "Frequent occurrence of respiratory symptoms in children is associated with exposure to air pollution, land use types, and parental mental health in the Greater Taipei area." Environmental research vol. 206 (2021): 112567. doi: https://doi.org/10.1016/j.envres.2021.112567
Zou ML, Jiang CB, Chen YH, Wu CD, Candice Lung SC, Chien LC, Kallawicha K, Lo YC, Chao HJ. Frequent occurrence of respiratory symptoms in children is associated with exposure to air pollution, land use types, and parental mental health in the Greater Taipei area. Environ Res. 2021 Dec 18;206:112567. doi: 10.1016/j.envres.2021.112567. Epub 2021 Dec 18. PMID: 34932981.
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Near-Infrared Light Brightens Bacterial Disinfection: Recent Progress and Perspectives.

ACS applied bio materials

Han Q, Lau JW, Do TC, Zhang Z, Xing B.
PMID: 35006816
ACS Appl Bio Mater. 2021 May 17;4(5):3937-3961. doi: 10.1021/acsabm.0c01341. Epub 2020 Dec 14.

Bacterial infection is a universal threat to public health, which not only causes many serious diseases but also exacerbates the condition of the patients of cancer, pandemic diseases,

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Han Q, Lau JW, Do TC, et al. Near-Infrared Light Brightens Bacterial Disinfection: Recent Progress and Perspectives. ACS Appl Bio Mater. 2020;4(5):3937-3961doi: 10.1021/acsabm.0c01341.
Han, Q., Lau, J. W., Do, T. C., Zhang, Z., & Xing, B. (2021). Near-Infrared Light Brightens Bacterial Disinfection: Recent Progress and Perspectives. ACS applied bio materials, 4(5), 3937-3961. https://doi.org/10.1021/acsabm.0c01341
Han, Qinyu, et al. "Near-Infrared Light Brightens Bacterial Disinfection: Recent Progress and Perspectives." ACS applied bio materials vol. 4,5 (2021): 3937-3961. doi: https://doi.org/10.1021/acsabm.0c01341
Han Q, Lau JW, Do TC, Zhang Z, Xing B. Near-Infrared Light Brightens Bacterial Disinfection: Recent Progress and Perspectives. ACS Appl Bio Mater. 2021 May 17;4(5):3937-3961. doi: 10.1021/acsabm.0c01341. Epub 2020 Dec 14. PMID: 35006816.
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[Study on difference of effect of Huoxue drugs and Yiqi Huoxue drugs on tumor metastasis based on immune remodeling].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Lu TC, Li J, Zhu GH, Wu JY, Yu JW, Zhu XY, Xu BW, Wang HP.
PMID: 34296574
Zhongguo Zhong Yao Za Zhi. 2021 Jun;46(11):2766-2772. doi: 10.19540/j.cnki.cjcmm.20210223.602.

Tumor metastasis is an important cause of tumor treatment failure. Its molecular mechanism is closely related to tumor cells remodeling immune cells and immunosuppressive microenvironment, so as to create a suitable soil for tumor cell invasion and growth. "Huoxue...

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Lu TC, Li J, Zhu GH, et al. [Study on difference of effect of Huoxue drugs and Yiqi Huoxue drugs on tumor metastasis based on immune remodeling]. Zhongguo Zhong Yao Za Zhi. 2021;46(11):2766-2772doi: 10.19540/j.cnki.cjcmm.20210223.602.
Lu, T. C., Li, J., Zhu, G. H., Wu, J. Y., Yu, J. W., Zhu, X. Y., Xu, B. W., & Wang, H. P. (2021). [Study on difference of effect of Huoxue drugs and Yiqi Huoxue drugs on tumor metastasis based on immune remodeling]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 46(11), 2766-2772. https://doi.org/10.19540/j.cnki.cjcmm.20210223.602
Lu, Tai-Cheng, et al. "[Study on difference of effect of Huoxue drugs and Yiqi Huoxue drugs on tumor metastasis based on immune remodeling]." Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica vol. 46,11 (2021): 2766-2772. doi: https://doi.org/10.19540/j.cnki.cjcmm.20210223.602
Lu TC, Li J, Zhu GH, Wu JY, Yu JW, Zhu XY, Xu BW, Wang HP. [Study on difference of effect of Huoxue drugs and Yiqi Huoxue drugs on tumor metastasis based on immune remodeling]. Zhongguo Zhong Yao Za Zhi. 2021 Jun;46(11):2766-2772. doi: 10.19540/j.cnki.cjcmm.20210223.602. Chinese. PMID: 34296574.
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Full-thickness macular hole formation in proliferative diabetic retinopathy.

Scientific reports

Tsui MC, Hsieh YT, Lai TT, Lai CT, Lin HC, Ho TC, Yang CH, Yang CM, Wang LC.
PMID: 34903770
Sci Rep. 2021 Dec 13;11(1):23839. doi: 10.1038/s41598-021-03239-2.

Twenty-one consecutive patients (21 eyes) having proliferative diabetic retinopathy (PDR) and fibrovascular proliferation (FVP) with optical coherence tomography (OCT) available before and after full-thickness macular hole (FTMH) formation were retrospectively reviewed. Four types of FTMH formation pathways in PDR...

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Tsui MC, Hsieh YT, Lai TT, et al. Full-thickness macular hole formation in proliferative diabetic retinopathy. Sci Rep. 2021;11(1):23839doi: 10.1038/s41598-021-03239-2.
Tsui, M. C., Hsieh, Y. T., Lai, T. T., Lai, C. T., Lin, H. C., Ho, T. C., Yang, C. H., Yang, C. M., & Wang, L. C. (2021). Full-thickness macular hole formation in proliferative diabetic retinopathy. Scientific reports, 11(1), 23839. https://doi.org/10.1038/s41598-021-03239-2
Tsui, Mei-Chi, et al. "Full-thickness macular hole formation in proliferative diabetic retinopathy." Scientific reports vol. 11,1 (2021): 23839. doi: https://doi.org/10.1038/s41598-021-03239-2
Tsui MC, Hsieh YT, Lai TT, Lai CT, Lin HC, Ho TC, Yang CH, Yang CM, Wang LC. Full-thickness macular hole formation in proliferative diabetic retinopathy. Sci Rep. 2021 Dec 13;11(1):23839. doi: 10.1038/s41598-021-03239-2. PMID: 34903770.
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On-Chip Biogenesis of Circulating NK Cell-Derived Exosomes in Non-Small Cell Lung Cancer Exhibits Antitumoral Activity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Kang YT, Niu Z, Hadlock T, Purcell E, Lo TW, Zeinali M, Owen S, Keshamouni VG, Reddy R, Ramnath N, Nagrath S.
PMID: 33747745
Adv Sci (Weinh). 2021 Jan 28;8(6):2003747. doi: 10.1002/advs.202003747. eCollection 2021 Mar.

As the recognition between natural killer (NK) cells and cancer cells does not require antigen presentation, NK cells are being actively studied for use in adoptive cell therapies in the rapidly evolving armamentarium of cancer immunotherapy. In addition to...

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Kang YT, Niu Z, Hadlock T, et al. On-Chip Biogenesis of Circulating NK Cell-Derived Exosomes in Non-Small Cell Lung Cancer Exhibits Antitumoral Activity. Adv Sci (Weinh). 2021;8(6):2003747doi: 10.1002/advs.202003747.
Kang, Y. T., Niu, Z., Hadlock, T., Purcell, E., Lo, T. W., Zeinali, M., Owen, S., Keshamouni, V. G., Reddy, R., Ramnath, N., & Nagrath, S. (2021). On-Chip Biogenesis of Circulating NK Cell-Derived Exosomes in Non-Small Cell Lung Cancer Exhibits Antitumoral Activity. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8(6), 2003747. https://doi.org/10.1002/advs.202003747
Kang, Yoon-Tae, et al. "On-Chip Biogenesis of Circulating NK Cell-Derived Exosomes in Non-Small Cell Lung Cancer Exhibits Antitumoral Activity." Advanced science (Weinheim, Baden-Wurttemberg, Germany) vol. 8,6 (2021): 2003747. doi: https://doi.org/10.1002/advs.202003747
Kang YT, Niu Z, Hadlock T, Purcell E, Lo TW, Zeinali M, Owen S, Keshamouni VG, Reddy R, Ramnath N, Nagrath S. On-Chip Biogenesis of Circulating NK Cell-Derived Exosomes in Non-Small Cell Lung Cancer Exhibits Antitumoral Activity. Adv Sci (Weinh). 2021 Jan 28;8(6):2003747. doi: 10.1002/advs.202003747. eCollection 2021 Mar. PMID: 33747745; PMCID: PMC7967048.
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Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans.

Proceedings of the National Academy of Sciences of the United States of America

Lo TH, Chen HL, Yao CI, Weng IC, Li CS, Huang CC, Chen NJ, Lin CH, Liu FT.
PMID: 34301890
Proc Natl Acad Sci U S A. 2021 Jul 27;118(30). doi: 10.1073/pnas.2026246118.

Cytosolic lipopolysaccharides (LPSs) bind directly to caspase-4/5/11 through their lipid A moiety, inducing inflammatory caspase oligomerization and activation, which is identified as the noncanonical inflammasome pathway. Galectins, β-galactoside-binding proteins, bind to various gram-negative bacterial LPS, which display β-galactoside-containing polysaccharide...

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Lo TH, Chen HL, Yao CI, et al. Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans. Proc Natl Acad Sci U S A. 2021;118(30)doi: 10.1073/pnas.2026246118.
Lo, T. H., Chen, H. L., Yao, C. I., Weng, I. C., Li, C. S., Huang, C. C., Chen, N. J., Lin, C. H., & Liu, F. T. (2021). Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans. Proceedings of the National Academy of Sciences of the United States of America, 118(30), . https://doi.org/10.1073/pnas.2026246118
Lo, Tzu-Han, et al. "Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans." Proceedings of the National Academy of Sciences of the United States of America vol. 118,30 (2021). doi: https://doi.org/10.1073/pnas.2026246118
Lo TH, Chen HL, Yao CI, Weng IC, Li CS, Huang CC, Chen NJ, Lin CH, Liu FT. Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30). doi: 10.1073/pnas.2026246118. PMID: 34301890; PMCID: PMC8325309.
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Showing 1033 to 1041 of 1041 entries