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Showing 13 to 24 of 133 entries
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Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression.

Oncotarget

Pye H, Butt MA, Funnell L, Reinert HW, Puccio I, Rehman Khan SU, Saouros S, Marklew JS, Stamati I, Qurashi M, Haidry R, Sehgal V, Oukrif D, Gandy M, Whitaker HC, Rodriguez-Justo M, Novelli M, Hamoudi R, Yahioglu G, Deonarain MP, Lovat LB.
PMID: 29796164
Oncotarget. 2018 May 01;9(33):22945-22959. doi: 10.18632/oncotarget.25159. eCollection 2018 May 01.

Early oesophageal adenocarcinoma (OA) and pre-neoplastic dysplasia may be treated with endoscopic resection and ablative techniques such as photodynamic therapy (PDT). Though effective, discrete areas of disease may be missed leading to recurrence. PDT further suffers from the side...

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Pye H, Butt MA, Funnell L, et al. Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression. Oncotarget. 2018;9(33):22945-22959doi: 10.18632/oncotarget.25159.
Pye, H., Butt, M. A., Funnell, L., Reinert, H. W., Puccio, I., Rehman Khan, S. U., Saouros, S., Marklew, J. S., Stamati, I., Qurashi, M., Haidry, R., Sehgal, V., Oukrif, D., Gandy, M., Whitaker, H. C., Rodriguez-Justo, M., Novelli, M., Hamoudi, R., Yahioglu, G., Deonarain, M. P., & Lovat, L. B. (2018). Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression. Oncotarget, 9(33), 22945-22959. https://doi.org/10.18632/oncotarget.25159
Pye, Hayley, et al. "Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression." Oncotarget vol. 9,33 (2018): 22945-22959. doi: https://doi.org/10.18632/oncotarget.25159
Pye H, Butt MA, Funnell L, Reinert HW, Puccio I, Rehman Khan SU, Saouros S, Marklew JS, Stamati I, Qurashi M, Haidry R, Sehgal V, Oukrif D, Gandy M, Whitaker HC, Rodriguez-Justo M, Novelli M, Hamoudi R, Yahioglu G, Deonarain MP, Lovat LB. Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression. Oncotarget. 2018 May 01;9(33):22945-22959. doi: 10.18632/oncotarget.25159. eCollection 2018 May 01. PMID: 29796164; PMCID: PMC5955430.
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Correlating tumor-infiltrating lymphocytes and lung cancer stem cells: a cross-sectional study.

Annals of translational medicine

Masciale V, Grisendi G, Banchelli F, D'Amico R, Maiorana A, Sighinolfi P, Pinelli M, Lovati E, Stefani A, Morandi U, Dominici M, Aramini B.
PMID: 31930020
Ann Transl Med. 2019 Nov;7(22):619. doi: 10.21037/atm.2019.11.27.

BACKGROUND: Lung cancer stem cells (LCSCs) are endowed with high aldehyde dehydrogenase (ALDH) expression and play roles in tumor proliferation, metastasis, and drug resistance. Their elusive nature may allow them to escape the immune response by tumor-infiltrating lymphocytes (TILs),...

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Masciale V, Grisendi G, Banchelli F, et al. Correlating tumor-infiltrating lymphocytes and lung cancer stem cells: a cross-sectional study. Ann Transl Med. 2019;7(22):619doi: 10.21037/atm.2019.11.27.
Masciale, V., Grisendi, G., Banchelli, F., D'Amico, R., Maiorana, A., Sighinolfi, P., Pinelli, M., Lovati, E., Stefani, A., Morandi, U., Dominici, M., & Aramini, B. (2019). Correlating tumor-infiltrating lymphocytes and lung cancer stem cells: a cross-sectional study. Annals of translational medicine, 7(22), 619. https://doi.org/10.21037/atm.2019.11.27
Masciale, Valentina, et al. "Correlating tumor-infiltrating lymphocytes and lung cancer stem cells: a cross-sectional study." Annals of translational medicine vol. 7,22 (2019): 619. doi: https://doi.org/10.21037/atm.2019.11.27
Masciale V, Grisendi G, Banchelli F, D'Amico R, Maiorana A, Sighinolfi P, Pinelli M, Lovati E, Stefani A, Morandi U, Dominici M, Aramini B. Correlating tumor-infiltrating lymphocytes and lung cancer stem cells: a cross-sectional study. Ann Transl Med. 2019 Nov;7(22):619. doi: 10.21037/atm.2019.11.27. PMID: 31930020; PMCID: PMC6944548.
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Music and Metronomes Differentially Impact Motor Timing in People with and without Parkinson's Disease: Effects of Slow, Medium, and Fast Tempi on Entrainment and Synchronization Performances in Finger Tapping, Toe Tapping, and Stepping on the Spot Tasks.

Parkinson's disease

Rose D, Delevoye-Turrell Y, Ott L, Annett LE, Lovatt PJ.
PMID: 31531220
Parkinsons Dis. 2019 Aug 18;2019:6530838. doi: 10.1155/2019/6530838. eCollection 2019.

INTRODUCTION: Rhythmic auditory stimulation (RAS) has successfully helped regulate gait for people with Parkinson's disease. However, the way in which different auditory cues and types of movements affect entrainment, synchronization, and pacing stability has not been directly compared in...

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Rose D, Delevoye-Turrell Y, Ott L, et al. Music and Metronomes Differentially Impact Motor Timing in People with and without Parkinson's Disease: Effects of Slow, Medium, and Fast Tempi on Entrainment and Synchronization Performances in Finger Tapping, Toe Tapping, and Stepping on the Spot Tasks. Parkinsons Dis. 2019;2019:6530838doi: 10.1155/2019/6530838.
Rose, D., Delevoye-Turrell, Y., Ott, L., Annett, L. E., & Lovatt, P. J. (2019). Music and Metronomes Differentially Impact Motor Timing in People with and without Parkinson's Disease: Effects of Slow, Medium, and Fast Tempi on Entrainment and Synchronization Performances in Finger Tapping, Toe Tapping, and Stepping on the Spot Tasks. Parkinson's disease, 20196530838. https://doi.org/10.1155/2019/6530838
Rose, Dawn, et al. "Music and Metronomes Differentially Impact Motor Timing in People with and without Parkinson's Disease: Effects of Slow, Medium, and Fast Tempi on Entrainment and Synchronization Performances in Finger Tapping, Toe Tapping, and Stepping on the Spot Tasks." Parkinson's disease vol. 2019 (2019): 6530838. doi: https://doi.org/10.1155/2019/6530838
Rose D, Delevoye-Turrell Y, Ott L, Annett LE, Lovatt PJ. Music and Metronomes Differentially Impact Motor Timing in People with and without Parkinson's Disease: Effects of Slow, Medium, and Fast Tempi on Entrainment and Synchronization Performances in Finger Tapping, Toe Tapping, and Stepping on the Spot Tasks. Parkinsons Dis. 2019 Aug 18;2019:6530838. doi: 10.1155/2019/6530838. eCollection 2019. PMID: 31531220; PMCID: PMC6721399.
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Established and Emerging Biomarkers in Cutaneous Malignant Melanoma.

Healthcare (Basel, Switzerland)

Verykiou S, Ellis RA, Lovat PE.
PMID: 27429260
Healthcare (Basel). 2014 Jan 14;2(1):60-73. doi: 10.3390/healthcare2010060.

In an era of personalized medicine, disease specific biomarkers play an increasing role in the stratification of high-risk patient groups. Cutaneous malignant melanoma is the most deadly form of skin cancer with an ever-increasing global incidence, especially in patients...

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Verykiou S, Ellis RA, Lovat PE. Established and Emerging Biomarkers in Cutaneous Malignant Melanoma. Healthcare (Basel). 2014;2(1):60-73doi: 10.3390/healthcare2010060.
Verykiou, S., Ellis, R. A., & Lovat, P. E. (2014). Established and Emerging Biomarkers in Cutaneous Malignant Melanoma. Healthcare (Basel, Switzerland), 2(1), 60-73. https://doi.org/10.3390/healthcare2010060
Verykiou, Stamatina, et al. "Established and Emerging Biomarkers in Cutaneous Malignant Melanoma." Healthcare (Basel, Switzerland) vol. 2,1 (2014): 60-73. doi: https://doi.org/10.3390/healthcare2010060
Verykiou S, Ellis RA, Lovat PE. Established and Emerging Biomarkers in Cutaneous Malignant Melanoma. Healthcare (Basel). 2014 Jan 14;2(1):60-73. doi: 10.3390/healthcare2010060. PMID: 27429260; PMCID: PMC4934494.
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Human-machine collaboration: bringing artificial intelligence into colonoscopy.

Frontline gastroenterology

Ahmad OF, Stoyanov D, Lovat LB.
PMID: 31205664
Frontline Gastroenterol. 2019 Apr;10(2):198-199. doi: 10.1136/flgastro-2018-101047. Epub 2018 Oct 15.

No abstract available.

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Ahmad OF, Stoyanov D, Lovat LB. Human-machine collaboration: bringing artificial intelligence into colonoscopy. Frontline Gastroenterol. 2018;10(2):198-199doi: 10.1136/flgastro-2018-101047.
Ahmad, O. F., Stoyanov, D., & Lovat, L. B. (2019). Human-machine collaboration: bringing artificial intelligence into colonoscopy. Frontline gastroenterology, 10(2), 198-199. https://doi.org/10.1136/flgastro-2018-101047
Ahmad, Omer F, et al. "Human-machine collaboration: bringing artificial intelligence into colonoscopy." Frontline gastroenterology vol. 10,2 (2019): 198-199. doi: https://doi.org/10.1136/flgastro-2018-101047
Ahmad OF, Stoyanov D, Lovat LB. Human-machine collaboration: bringing artificial intelligence into colonoscopy. Frontline Gastroenterol. 2019 Apr;10(2):198-199. doi: 10.1136/flgastro-2018-101047. Epub 2018 Oct 15. PMID: 31205664; PMCID: PMC6540265.
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ACTH-dependent Cushing's Syndrome: Diagnostic Pitfalls in Concomitant Non-secreting Pituitary Adenomas.

European journal of case reports in internal medicine

Lucotti P, Zoia C, Lovati E, Gaetani P, Corazza GR.
PMID: 30755868
Eur J Case Rep Intern Med. 2016 Mar 30;3(3):000389. doi: 10.12890/2016_000389. eCollection 2016.

OBJECTIVES: To describe the possible pitfalls in correctly interpreting clinical, radiological and biochemical findings in ACTH-dependent Cushing's syndrome.METHODS: We describe a case of a pituitary adenoma visualized at MRI not correlated with an ACTH-dependent Cushing's syndrome.RESULTS: Radiological imaging and...

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Lucotti P, Zoia C, Lovati E, et al. ACTH-dependent Cushing's Syndrome: Diagnostic Pitfalls in Concomitant Non-secreting Pituitary Adenomas. Eur J Case Rep Intern Med. 2016;3(3):000389doi: 10.12890/2016_000389.
Lucotti, P., Zoia, C., Lovati, E., Gaetani, P., & Corazza, G. R. (2016). ACTH-dependent Cushing's Syndrome: Diagnostic Pitfalls in Concomitant Non-secreting Pituitary Adenomas. European journal of case reports in internal medicine, 3(3), 000389. https://doi.org/10.12890/2016_000389
Lucotti, Pietro, et al. "ACTH-dependent Cushing's Syndrome: Diagnostic Pitfalls in Concomitant Non-secreting Pituitary Adenomas." European journal of case reports in internal medicine vol. 3,3 (2016): 000389. doi: https://doi.org/10.12890/2016_000389
Lucotti P, Zoia C, Lovati E, Gaetani P, Corazza GR. ACTH-dependent Cushing's Syndrome: Diagnostic Pitfalls in Concomitant Non-secreting Pituitary Adenomas. Eur J Case Rep Intern Med. 2016 Mar 30;3(3):000389. doi: 10.12890/2016_000389. eCollection 2016. PMID: 30755868; PMCID: PMC6346901.
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Into the Blue: Ketene Multicomponent Reactions under Visible Light.

The Journal of organic chemistry

Capurro P, Lambruschini C, Lova P, Moni L, Basso A.
PMID: 33822607
J Org Chem. 2021 Apr 16;86(8):5845-5851. doi: 10.1021/acs.joc.1c00278. Epub 2021 Apr 06.

For the first time, a detailed study on the photophysical properties of variously substituted diazoketones and on their photoreactivity under blue LED irradiation was carried out. Despite very limited absorbance in the visible region, we have demonstrated that, independently...

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Capurro P, Lambruschini C, Lova P, et al. Into the Blue: Ketene Multicomponent Reactions under Visible Light. J Org Chem. 2021;86(8):5845-5851doi: 10.1021/acs.joc.1c00278.
Capurro, P., Lambruschini, C., Lova, P., Moni, L., & Basso, A. (2021). Into the Blue: Ketene Multicomponent Reactions under Visible Light. The Journal of organic chemistry, 86(8), 5845-5851. https://doi.org/10.1021/acs.joc.1c00278
Capurro, Pietro, et al. "Into the Blue: Ketene Multicomponent Reactions under Visible Light." The Journal of organic chemistry vol. 86,8 (2021): 5845-5851. doi: https://doi.org/10.1021/acs.joc.1c00278
Capurro P, Lambruschini C, Lova P, Moni L, Basso A. Into the Blue: Ketene Multicomponent Reactions under Visible Light. J Org Chem. 2021 Apr 16;86(8):5845-5851. doi: 10.1021/acs.joc.1c00278. Epub 2021 Apr 06. PMID: 33822607; PMCID: PMC8154565.
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Clonal transitions and phenotypic evolution in Barrett esophagus.

Gastroenterology

Evans JA, Carlotti E, Lin ML, Hackett RJ, Haughey MJ, Passman AM, Dunn L, Elia G, Porter RJ, McLean MH, Hughes F, ChinAleong J, Woodland P, Preston SL, Griffin SM, Lovat L, Rodriguez-Justo M, Huang W, Wright NA, Jansen M, McDonald SA.
PMID: 34973296
Gastroenterology. 2021 Dec 29; doi: 10.1053/j.gastro.2021.12.271. Epub 2021 Dec 29.

AIMS: Barrett esophagus (BE) is a risk factor for esophageal adenocarcinoma but our understanding of how it evolves is poorly understood. We investigated BE gland phenotype distribution, the clonal nature of phenotypic change and how phenotypic diversity plays a...

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Evans JA, Carlotti E, Lin ML, et al. Clonal transitions and phenotypic evolution in Barrett esophagus. Gastroenterology. 2021;doi: 10.1053/j.gastro.2021.12.271.
Evans, J. A., Carlotti, E., Lin, M. L., Hackett, R. J., Haughey, M. J., Passman, A. M., Dunn, L., Elia, G., Porter, R. J., McLean, M. H., Hughes, F., ChinAleong, J., Woodland, P., Preston, S. L., Griffin, S. M., Lovat, L., Rodriguez-Justo, M., Huang, W., Wright, N. A., Jansen, M., & McDonald, S. A. (2021). Clonal transitions and phenotypic evolution in Barrett esophagus. Gastroenterology, . https://doi.org/10.1053/j.gastro.2021.12.271
Evans, James A, et al. "Clonal transitions and phenotypic evolution in Barrett esophagus." Gastroenterology vol. (2021). doi: https://doi.org/10.1053/j.gastro.2021.12.271
Evans JA, Carlotti E, Lin ML, Hackett RJ, Haughey MJ, Passman AM, Dunn L, Elia G, Porter RJ, McLean MH, Hughes F, ChinAleong J, Woodland P, Preston SL, Griffin SM, Lovat L, Rodriguez-Justo M, Huang W, Wright NA, Jansen M, McDonald SA. Clonal transitions and phenotypic evolution in Barrett esophagus. Gastroenterology. 2021 Dec 29; doi: 10.1053/j.gastro.2021.12.271. Epub 2021 Dec 29. PMID: 34973296.
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Radiofrequency ablation for Barrett's oesophagus related neoplasia with the 360 Express catheter: initial experience from the United Kingdom and Ireland-preliminary results.

Surgical endoscopy

Magee CG, Graham D, Gordon C, Dunn J, Penman I, Willert R, Smart H, Ortiz-Fernandez-Sordo J, Ragunath K, Everson M, Alzoubaidi D, Banks M, Morris D, Sami S, Morris AJ, Bhandari P, Narayanasamy R, Di Pietro M, Lovat LB, Haidry R.
PMID: 33547491
Surg Endosc. 2022 Jan;36(1):598-606. doi: 10.1007/s00464-021-08325-0. Epub 2021 Feb 05.

BACKGROUND: Radio-frequency ablation (RFA) for Barrett's oesophagus (BE)-related neoplasia is currently used after endoscopic resection of visible neoplasia. The HALO 360 balloon has been used to ablate long segment BE. The Barrx™ 360 Express RFA self-sizing catheter ('RFA Express')...

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Magee CG, Graham D, Gordon C, et al. Radiofrequency ablation for Barrett's oesophagus related neoplasia with the 360 Express catheter: initial experience from the United Kingdom and Ireland-preliminary results. Surg Endosc. 2021;36(1):598-606doi: 10.1007/s00464-021-08325-0.
Magee, C. G., Graham, D., Gordon, C., Dunn, J., Penman, I., Willert, R., Smart, H., Ortiz-Fernandez-Sordo, J., Ragunath, K., Everson, M., Alzoubaidi, D., Banks, M., Morris, D., Sami, S., Morris, A. J., Bhandari, P., Narayanasamy, R., Di Pietro, M., Lovat, L. B., & Haidry, R. (2022). Radiofrequency ablation for Barrett's oesophagus related neoplasia with the 360 Express catheter: initial experience from the United Kingdom and Ireland-preliminary results. Surgical endoscopy, 36(1), 598-606. https://doi.org/10.1007/s00464-021-08325-0
Magee, Cormac G, et al. "Radiofrequency ablation for Barrett's oesophagus related neoplasia with the 360 Express catheter: initial experience from the United Kingdom and Ireland-preliminary results." Surgical endoscopy vol. 36,1 (2022): 598-606. doi: https://doi.org/10.1007/s00464-021-08325-0
Magee CG, Graham D, Gordon C, Dunn J, Penman I, Willert R, Smart H, Ortiz-Fernandez-Sordo J, Ragunath K, Everson M, Alzoubaidi D, Banks M, Morris D, Sami S, Morris AJ, Bhandari P, Narayanasamy R, Di Pietro M, Lovat LB, Haidry R. Radiofrequency ablation for Barrett's oesophagus related neoplasia with the 360 Express catheter: initial experience from the United Kingdom and Ireland-preliminary results. Surg Endosc. 2022 Jan;36(1):598-606. doi: 10.1007/s00464-021-08325-0. Epub 2021 Feb 05. PMID: 33547491.
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New Insights into Epigenetic Regulation of T Cell Differentiation.

Cells

Dutta A, Venkataganesh H, Love PE.
PMID: 34943965
Cells. 2021 Dec 08;10(12). doi: 10.3390/cells10123459.

Immature CD4

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Dutta A, Venkataganesh H, Love PE. New Insights into Epigenetic Regulation of T Cell Differentiation. Cells. 2021;10(12)doi: 10.3390/cells10123459.
Dutta, A., Venkataganesh, H., & Love, P. E. (2021). New Insights into Epigenetic Regulation of T Cell Differentiation. Cells, 10(12), . https://doi.org/10.3390/cells10123459
Dutta, Avik, et al. "New Insights into Epigenetic Regulation of T Cell Differentiation." Cells vol. 10,12 (2021). doi: https://doi.org/10.3390/cells10123459
Dutta A, Venkataganesh H, Love PE. New Insights into Epigenetic Regulation of T Cell Differentiation. Cells. 2021 Dec 08;10(12). doi: 10.3390/cells10123459. PMID: 34943965.
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Deep learning-based anatomical site classification for upper gastrointestinal endoscopy.

International journal of computer assisted radiology and surgery

He Q, Bano S, Ahmad OF, Yang B, Chen X, Valdastri P, Lovat LB, Stoyanov D, Zuo S.
PMID: 32377939
Int J Comput Assist Radiol Surg. 2020 Jul;15(7):1085-1094. doi: 10.1007/s11548-020-02148-5. Epub 2020 May 06.

PURPOSE: Upper gastrointestinal (GI) endoscopic image documentation has provided an efficient, low-cost solution to address quality control for endoscopic reporting. The problem is, however, challenging for computer-assisted techniques, because different sites have similar appearances. Additionally, across different patients, site...

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He Q, Bano S, Ahmad OF, et al. Deep learning-based anatomical site classification for upper gastrointestinal endoscopy. Int J Comput Assist Radiol Surg. 2020;15(7):1085-1094doi: 10.1007/s11548-020-02148-5.
He, Q., Bano, S., Ahmad, O. F., Yang, B., Chen, X., Valdastri, P., Lovat, L. B., Stoyanov, D., & Zuo, S. (2020). Deep learning-based anatomical site classification for upper gastrointestinal endoscopy. International journal of computer assisted radiology and surgery, 15(7), 1085-1094. https://doi.org/10.1007/s11548-020-02148-5
He, Qi, et al. "Deep learning-based anatomical site classification for upper gastrointestinal endoscopy." International journal of computer assisted radiology and surgery vol. 15,7 (2020): 1085-1094. doi: https://doi.org/10.1007/s11548-020-02148-5
He Q, Bano S, Ahmad OF, Yang B, Chen X, Valdastri P, Lovat LB, Stoyanov D, Zuo S. Deep learning-based anatomical site classification for upper gastrointestinal endoscopy. Int J Comput Assist Radiol Surg. 2020 Jul;15(7):1085-1094. doi: 10.1007/s11548-020-02148-5. Epub 2020 May 06. PMID: 32377939; PMCID: PMC7316667.
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ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma.

Cancers

Wu CE, Koay TS, Esfandiari A, Ho YH, Lovat P, Lunec J.
PMID: 30577494
Cancers (Basel). 2018 Dec 20;11(1). doi: 10.3390/cancers11010003.

MAPK and p14

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Wu CE, Koay TS, Esfandiari A, et al. ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma. Cancers (Basel). 2018;11(1)doi: 10.3390/cancers11010003.
Wu, C. E., Koay, T. S., Esfandiari, A., Ho, Y. H., Lovat, P., & Lunec, J. (2018). ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma. Cancers, 11(1), . https://doi.org/10.3390/cancers11010003
Wu, Chiao-En, et al. "ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma." Cancers vol. 11,1 (2018). doi: https://doi.org/10.3390/cancers11010003
Wu CE, Koay TS, Esfandiari A, Ho YH, Lovat P, Lunec J. ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma. Cancers (Basel). 2018 Dec 20;11(1). doi: 10.3390/cancers11010003. PMID: 30577494; PMCID: PMC6356368.
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Showing 13 to 24 of 133 entries