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Showing 9985 to 9996 of 59317 entries
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Impact of renin-angiotensin system inhibitors on long-term clinical outcomes of patients with rheumatic heart disease.

ESC heart failure

Liu C, Lai Y, Wu D, Fu R, Li Y, Li H, Guan T, Shen Y.
PMID: 34545695
ESC Heart Fail. 2021 Dec;8(6):5338-5351. doi: 10.1002/ehf2.13623. Epub 2021 Sep 20.

AIMS: Rheumatic heart disease (RHD) remains a major global health problem. Renin-angiotensin-aldosterone system inhibitors (RAASi) are commonly administered in the treatment of cardiovascular disease, but its role in RHD patients is still limited. We performed a retrospective study to...

Differentiation of Electric Response in Highly Oriented Regioregular Poly(3-hexylthiophene) under Anisotropic Strain.

ACS applied materials & interfaces

Li J, Li H, Ren Z, Yan S, Sun X.
PMID: 33412844
ACS Appl Mater Interfaces. 2021 Jan 20;13(2):2944-2951. doi: 10.1021/acsami.0c19199. Epub 2021 Jan 07.

Exploring flexible and stretchable conjugated polymer devices has garnered particular attention. This work provides a new technology to improve the electrical properties in a stretching process by skillfully assisting the anisotropic tensile properties of oriented regioregular poly(3-hexylthiophene) (P3HT) films....

A Novel Risk-Stratification Models of the High-Flow Nasal Cannula Therapy in COVID-19 Patients With Hypoxemic Respiratory Failure.

Frontiers in medicine

Xu J, Yang X, Huang C, Zou X, Zhou T, Pan S, Yang L, Wu Y, Ouyang Y, Wang Y, Xu D, Zhao X, Shu H, Jiang Y, Xiong W, Ren L, Liu H, Yuan Y, Qi H, Fu S, Chen D, Zhang D, Yuan S, Shang Y.
PMID: 33425951
Front Med (Lausanne). 2020 Dec 08;7:607821. doi: 10.3389/fmed.2020.607821. eCollection 2020.

No abstract available.

Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson's Disease.

Frontiers in neuroscience

Li H, Wang H, Zhang L, Wang M, Li Y.
PMID: 34121985
Front Neurosci. 2021 May 28;15:647266. doi: 10.3389/fnins.2021.647266. eCollection 2021.

BACKGROUND: Aggregation and neurotoxicity of the presynaptic protein α-synuclein and the progressive loss of nigral dopaminergic neurons are believed to be the key hallmarks of Parkinson's disease (PD). A53T mutant α-synuclein causes early onset PD and more severe manifestations....

MOF-Derived ZnS Nanodots/Ti.

Nano-micro letters

Cao B, Liu H, Zhang X, Zhang P, Zhu Q, Du H, Wang L, Zhang R, Xu B.
PMID: 34568995
Nanomicro Lett. 2021 Sep 26;13(1):202. doi: 10.1007/s40820-021-00728-x.

ZnS has great potentials as an anode for lithium storage because of its high theoretical capacity and resource abundance; however, the large volume expansion accompanied with structural collapse and low conductivity of ZnS cause severe capacity fading and inferior...

Impact of anesthetic strategy on outcomes for patients with acute basilar artery occlusion undergoing mechanical thrombectomy.

Journal of neurointerventional surgery

Li F, Wan J, Song J, Yuan J, Kong W, Huang J, Luo W, Wu D, Li L, Chen L, Zhao C, Chen J, Tao H, Sang H, Qiu Z, Zi W, Yang Q, Chen X, Li H, Peng F.
PMID: 34732534
J Neurointerv Surg. 2021 Nov 03; doi: 10.1136/neurintsurg-2021-018000. Epub 2021 Nov 03.

BACKGROUND: The best anesthetic management strategy for patients with acute large vessel occlusion treated with mechanical thrombectomy (MT) remains uncertain. Most studies have focused on anterior-circulation stroke caused by large artery occlusion. Nevertheless, limited data are available on the...

Relationships between microbial activity, enzyme activities and metal(loid) form in NiCu tailings area.

The Science of the total environment

Li H, Yao J, Min N, Liu J, Chen Z, Zhu X, Zhao C, Pang W, Li M, Cao Y, Liu B, Duran R.
PMID: 34906578
Sci Total Environ. 2021 Dec 11;812:152326. doi: 10.1016/j.scitotenv.2021.152326. Epub 2021 Dec 11.

Here we combined microcalorimetry, enzyme activity measurements, and characterization of metal form in order to evaluate the effect of metal(loid)s on the activity of microbial community inhabiting tailings area with high toxic metal(loid)s concentration. Chromium (Cr), nickel (Ni), copper...

Corrigendum to "Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats" Toxicology and Applied Pharmacology, volume 412C (2021).

Toxicology and applied pharmacology

Yu L, Lu H, Yang X, Li R, Shi J, Yu Y, Ma C, Sun F, Zhang S, Zhang F.
PMID: 33508267
Toxicol Appl Pharmacol. 2021 Mar 01;414:115423. doi: 10.1016/j.taap.2021.115423. Epub 2021 Jan 26.

No abstract available.

Association of Gestational Age at Birth With Subsequent Suspected Developmental Coordination Disorder in Early Childhood in China.

JAMA network open

Hua J, Barnett AL, Williams GJ, Dai X, Sun Y, Li H, Chen G, Wang L, Feng J, Liu Y, Zhang L, Zhu L, Weng T, Guan H, Gu Y, Zhou Y, Butcher A, Du W.
PMID: 34905005
JAMA Netw Open. 2021 Dec 01;4(12):e2137581. doi: 10.1001/jamanetworkopen.2021.37581.

IMPORTANCE: It remains unknown whether children born at different degrees of prematurity, early term, and post term might have a higher risk of developmental coordination disorder (DCD) compared with completely full-term children (39-40 gestational weeks).OBJECTIVE: To differentiate between suspected...

Age-dependent neurological phenotypes in a mouse model of PRRT2-related diseases.

Neurogenetics

Aj F, T M, C I, C BM, Kj N, H L, A N, Sm V, Y-H F, Lj P.
PMID: 34101060
Neurogenetics. 2021 Jul;22(3):171-185. doi: 10.1007/s10048-021-00645-6. Epub 2021 Jun 08.

Paroxysmal kinesigenic dyskinesia is an episodic movement disorder caused by dominant mutations in the proline-rich transmembrane protein PRRT2, with onset in childhood and typically with improvement or resolution by middle age. Mutations in the same gene may also cause...

COVID-19 vaccine hesitancy: The effects of combining direct and indirect online opinion cues on psychological reactance to health campaigns.

Computers in human behavior

Lu F, Sun Y.
PMID: 34707328
Comput Human Behav. 2022 Feb;127:107057. doi: 10.1016/j.chb.2021.107057. Epub 2021 Oct 22.

This study aims to examine whether and how user-generated comments and reaction emojis on COVID-19 vaccine-promoting Facebook posts induce psychological reactance to posts and vaccine hesitancy in audiences of the posts. An online experiment including 465 American adults showed...

Manifold medicine: A schema that expands treatment dimensionality.

Drug discovery today

Ung CY, Weiskittel TM, Correia C, Kaufmann SH, Li H.
PMID: 34600126
Drug Discov Today. 2022 Jan;27(1):8-16. doi: 10.1016/j.drudis.2021.09.016. Epub 2021 Sep 29.

Drug discovery currently focuses on identifying new druggable targets and drug repurposing. Here, we illustrate a third domain of drug discovery: the dimensionality of treatment regimens. We formulate a new schema called 'Manifold Medicine', in which disease states are...

Showing 9985 to 9996 of 59317 entries