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Showing 13 to 24 of 84 entries
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Unlocking the causal link of metabolically different adiposity subtypes with brain volumes and the risks of dementia and stroke: A Mendelian randomization study.

Neurobiology of aging

Mulugeta A, Lumsden A, Hyppönen E.
PMID: 33770530
Neurobiol Aging. 2021 Jun;102:161-169. doi: 10.1016/j.neurobiolaging.2021.02.010. Epub 2021 Feb 21.

To establish causal evidence for the association of adiposity-related metabolic abnormalities with brain volumes, and the risks of dementia and stroke, we applied 1- and 2-sample Mendelian randomization (MR) analyses using up to 336,309 UK Biobank participants. We used...

Prevalence of substance use disorders in an urban and a rural area in Suriname.

Tropical medicine and health

Jadnanansing R, Blankers M, Dwarkasing R, Etwaroo K, Lumsden V, Dekker J, Bipat R.
PMID: 33526098
Trop Med Health. 2021 Feb 02;49(1):12. doi: 10.1186/s41182-021-00301-7.

BACKGROUND: Alcohol use disorders (AUD) have the worst impact in low-middle-income countries (LMICs), where the disease burden per liter of alcohol consumed is higher than in wealthy populations. Furthermore, the median treatment gap for AUDs in LMICs is 78.1%....

Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in rodents.

Pain

Castro J, Garcia-Caraballo S, Maddern J, Schober G, Lumsden A, Harrington A, Schmiel S, Lindstrom B, Adams J, Brierley SM.
PMID: 33863856
Pain. 2022 Jan 01;163(1):e72-e86. doi: 10.1097/j.pain.0000000000002314.

ABSTRACT: Abdominal pain is a key symptom of inflammatory bowel disease and irritable bowel syndrome, for which there are inadequate therapeutic options. We tested whether olorinab-a highly selective, full agonist of the cannabinoid receptor 2 (CB2)-reduced visceral hypersensitivity in...

Measuring Advanced/Extended Practice Roles in Arthritis and Musculoskeletal Care in Canada.

ACR open rheumatology

Lundon K, Inrig T, Paton M, Shupak R, Kennedy C, McGlynn M, Barber C.
PMID: 32277867
ACR Open Rheumatol. 2020 Apr;2(4):242-250. doi: 10.1002/acr2.11129. Epub 2020 Apr 11.

OBJECTIVE: Our objective was to characterize Canadian workforce attributes of extended role practitioners (ERPs) in arthritis care.METHODS: We used an exploratory, mixed-methods study that was based on the Canadian Rheumatology Association's Stand Up and Be Counted Rheumatologist Workforce Survey...

Dynamics of single and multiple bubbles and associated heat transfer in nucleate boiling under low gravity conditions.

Annals of the New York Academy of Sciences

Qiu D, Son G, Dhir VK, Chao D, Logsdon K.
PMID: 12446337
Ann N Y Acad Sci. 2002 Oct;974:378-97. doi: 10.1111/j.1749-6632.2002.tb05920.x.

Experimental studies and numerical simulation of growth and lift-off processes of single bubbles formed on designed nucleation sites have been conducted under low-gravity conditions. Merging of multiple bubbles and lift-off processes during boiling of water in the parabola flights...

Trace metals in the hair of habitants of the Ok Tedi region, Papua New Guinea.

Environmental pollution (Barking, Essex : 1987)

Jones GL, Willy D, Lumsden B, Taufa T, Lourie J.
PMID: 15092690
Environ Pollut. 1987;48(2):101-15. doi: 10.1016/0269-7491(87)90090-x.

It has long been known that mining activity can markedly change the level and distribution of certain heavy metals in the adjacent environment. This pollution can be quite widespread and long lasting and often has deleterious effects on the...

Neuroendovascular-specific engineering modifications to the CorPath GRX Robotic System.

Journal of neurosurgery

Britz GW, Panesar SS, Falb P, Tomas J, Desai V, Lumsden A.
PMID: 31783367
J Neurosurg. 2019 Nov 29;1-7. doi: 10.3171/2019.9.JNS192113. Epub 2019 Nov 29.

OBJECTIVE: The aim of this study was to evaluate new, neuroendovascular-specific engineering and software modifications to the CorPath GRX Robotic System for their ability to support safer and more effective cranial neurovascular interventions in a preclinical model.METHODS: Active device...

Phosphorus acquisition by citrate- and phytase-exuding Nicotiana tabacum plant mixtures depends on soil phosphorus availability and root intermingling.

Physiologia plantarum

Giles CD, Richardson AE, Cade-Menun BJ, Mezeli MM, Brown LK, Menezes-Blackburn D, Darch T, Blackwell MS, Shand CA, Stutter MI, Wendler R, Cooper P, Lumsdon DG, Wearing C, Zhang H, Haygarth PM, George TS.
PMID: 29498417
Physiol Plant. 2018 Mar 02; doi: 10.1111/ppl.12718. Epub 2018 Mar 02.

Citrate and phytase root exudates contribute to improved phosphorus (P) acquisition efficiency in Nicotiana tabacum (tobacco) when both exudates are produced in a P deficient soil. To test the importance of root intermingling in the interaction of citrate and...

Laser-wakefield accelerators for high-resolution X-ray imaging of complex microstructures.

Scientific reports

Hussein AE, Senabulya N, Ma Y, Streeter MJV, Kettle B, Dann SJD, Albert F, Bourgeois N, Cipiccia S, Cole JM, Finlay O, Gerstmayr E, González IG, Higginbotham A, Jaroszynski DA, Falk K, Krushelnick K, Lemos N, Lopes NC, Lumsdon C, Lundh O, Mangles SPD, Najmudin Z, Rajeev PP, Schlepütz CM, Shahzad M, Smid M, Spesyvtsev R, Symes DR, Vieux G, Willingale L, Wood JC, Shahani AJ, Thomas AGR.
PMID: 30824838
Sci Rep. 2019 Mar 01;9(1):3249. doi: 10.1038/s41598-019-39845-4.

Laser-wakefield accelerators (LWFAs) are high acceleration-gradient plasma-based particle accelerators capable of producing ultra-relativistic electron beams. Within the strong focusing fields of the wakefield, accelerated electrons undergo betatron oscillations, emitting a bright pulse of X-rays with a micrometer-scale source size...

Corrigendum: Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia.

Nature genetics

Meyer E, Carss KJ, Rankin J, Nichols JME, Grozeva D, Joseph AP, Mencacci NE, Papandreou A, Ng J, Barral S, Ngoh A, Ben-Pazi H, Willemsen MA, Arkadir D, Barnicoat A, Bergman H, Bhate S, Boys A, Darin N, Foulds N, Gutowski N, Hills A, Houlden H, Hurst JA, Israel Z, Kaminska M, Limousin P, Lumsden D, McKee S, Misra S, Mohammed SS, Nakou V, Nicolai J, Nilsson M, Pall H, Peall KJ, Peters GB, Prabhakar P, Reuter MS, Rump P, Segel R, Sinnema M, Smith M, Turnpenny P, White SM, Wieczorek D, Wiethoff S, Wilson BT, Winter G, Wragg C, Pope S, Heales SJH, Morrogh D, Pittman A, Carr LJ, Perez-Dueñas B, Lin JP, Reis A, Gahl WA, Toro C, Bhatia KP, Wood NW, Kamsteeg EJ, Chong WK, Gissen P, Topf M, Dale RC, Chubb JR, Raymond FL, Kurian MA.
PMID: 28546572
Nat Genet. 2017 May 26;49(6):969. doi: 10.1038/ng0617-969b.

No abstract available.

Poisonous substances.

Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association

Lumsden K.
PMID: 27715237
Emerg Nurse. 2012 Dec 06;20(8):15. doi: 10.7748/en.20.8.15.s9.

Management plans for children with ingestion problems who present to emergency departments often include toxicology screening tests to detect the presence of poisonous substances.

Hypervalent, low-coordinate phosphorus(III) centers in complexes of the phosphadiazonium cation with chelate ligands.

Journal of the American Chemical Society

Burford N, Phillips AD, Spinney HA, Lumsden M, Werner-Zwanziger U, Ferguson MJ, McDonald R.
PMID: 15771528
J Am Chem Soc. 2005 Mar 23;127(11):3921-7. doi: 10.1021/ja043691y.

Trifluoromethylsulfonyloxy-(2,4,6-tri-tert-butylphenylimino)phosphine, Mes*NPOTf (Mes = 2,4,6-tri-tert-butylphenyl, OTf = trifluoromethanesulfonate, triflate) reacts quantitatively with the multifunctional ligands 2,2'-bipyridine (2,2'-BIPY), N,N,N',N'-tetramethylethylenediamine (TMEDA), 1,2-bis(diethylphosphino)ethane (DEPE), 1,2-bis(diphenylphosphino)ethane (DIPHOS), and N,N,N',N' ',N' '-pentamethyldiethylenetriamine (PMDETA) to give the Lewis acid-base complexes [Mes*NP(2,2'-BIPY)][OTf], [Mes*NP(TMEDA)][OTf], [Mes*NP(DIPHOS)][OTf], [Mes*NP(DEPE)][OTf], and...

Showing 13 to 24 of 84 entries