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Showing 25 to 36 of 315 entries
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Long-Term Use of Temozolomide as Safe and Effective Therapy for an Aggressive Corticotroph Adenoma in a Very Old Patient.

Journal of the Endocrine Society

Decaroli MC, Ansaloni A, Monzani ML, Losa M, Zunarelli E, Rochira V, Madeo B.
PMID: 34195524
J Endocr Soc. 2021 Apr 10;5(8):bvab065. doi: 10.1210/jendso/bvab065. eCollection 2021 Aug 01.

BACKGROUND: Temozolomide (TMZ) is safe and effective in the treatment of aggressive pituitary adenomas (PAs). However, the optimal duration of TMZ therapy is still unknown. Moreover, data about administration of TMZ in elderly (≥65 years) people to treat aggressive...

Risk factors for problematic alcohol use among male waste pickers and caddies in Johannesburg, South Africa: a cross-sectional study.

Archives of environmental & occupational health

Mdleleni S, Naicker N, Made F, Ntlebi V, Kootbodien T, Tlotleng N, Makhubele M, Wilson K.
PMID: 33555240
Arch Environ Occup Health. 2021 Feb 08;1-11. doi: 10.1080/19338244.2021.1879720. Epub 2021 Feb 08.

Informal workers may be prone to problematic substance use due to many factors, including adverse working conditions and low income. The aim of this secondary analysis was to investigate problematic alcohol use risk factors among male informal workers in...

Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.

The Journal of clinical investigation

Li L, Guturi KKN, Gautreau B, Patel PS, Saad A, Morii M, Mateo F, Palomero L, Barbour H, Gomez A, Ng D, Kotlyar M, Pastrello C, Jackson HW, Khokha R, Jurisica I, Affar EB, Raught B, Sanchez O, Alaoui-Jamali M, Pujana MA, Hakem A, Hakem R.
PMID: 34196309
J Clin Invest. 2021 Jul 01;131(13). doi: 10.1172/JCI152424.

No abstract available.

Management of Type 2 Diabetes in Developing Countries: Balancing Optimal Glycaemic Control and Outcomes with Affordability and Accessibility to Treatment.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Mohan V, Khunti K, Chan SP, Filho FF, Tran NQ, Ramaiya K, Joshi S, Mithal A, Mbaye MN, Nicodemus NA, Latt TS, Ji L, Elebrashy IN, Mbanya JC.
PMID: 31773420
Diabetes Ther. 2020 Jan;11(1):15-35. doi: 10.1007/s13300-019-00733-9. Epub 2019 Nov 26.

With the growing prevalence of type 2 diabetes, particularly in emerging countries, its management in the context of available resources should be considered. International guidelines, while comprehensive and scientifically valid, may not be appropriate for regions such as Asia,...

Spermidine supplementation in rare translation-associated disorders.

Cell stress

Zimmermann A, Carmona-Gutierrez D, Madeo F.
PMID: 33688620
Cell Stress. 2021 Mar 08;5(3):29-32. doi: 10.15698/cst2021.03.243.

The polyamine spermidine is essential for protein translation in eukaryotes, both as a substrate for the hypusination of the translation initiation factor eIF5A as well as general translational fidelity. Dwindling spermidine levels during aging have been implicated in reduced...

Insights and clinical potential of proteomics in understanding spermatogenesis.

Expert review of proteomics

Ribeiro JC, Alves MG, Amado F, Ferreira R, Oliveira P.
PMID: 33567922
Expert Rev Proteomics. 2021 Jan;18(1):13-25. doi: 10.1080/14789450.2021.1889373. Epub 2021 Mar 04.

No abstract available.

The impact of war on the health system of the Tigray region in Ethiopia: an assessment.

BMJ global health

Gesesew H, Berhane K, Siraj ES, Siraj D, Gebregziabher M, Gebre YG, Gebreslassie SA, Amdes F, Tesema AG, Siraj A, Aregawi M, Gezahegn S, Tesfay FH.
PMID: 34815244
BMJ Glob Health. 2021 Nov;6(11). doi: 10.1136/bmjgh-2021-007328.

The war in Tigray region of Ethiopia that started in November 2020 and is still ongoing has brought enormous damage to the health system. This analysis provides an assessment of the health system before and during the war. Evidence...

Isolated Horner Syndrome as the Only Manifestation of a Large Intrathoracic Schwannoma.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Moinul P, Rebello R, Rodriguez AR.
PMID: 33631092
Can J Neurol Sci. 2022 Jan;49(1):149-150. doi: 10.1017/cjn.2021.33. Epub 2021 Feb 26.

No abstract available.

Determinants of oxygen uptake and prognostic factors in cardiopulmonary exercise test in patients with Fontan surgery.

Cardiology in the young

Martin Talavera M, Manso B, Cejudo Ramos P, Rodriguez Puras MJ, Wals Rodriguez AJ, Garcia de Vinuesa PG.
PMID: 34602111
Cardiol Young. 2021 Oct 04;1-4. doi: 10.1017/S1047951121004054. Epub 2021 Oct 04.

INTRODUCTION: Cardiopulmonary exercise test (CPET) allows quantification of functional capacity of patients with Fontan. The objective of this study was to determine the role of CPET parameters in predicting a higher maximum oxygen consumption (VO2 max) and to analyse...

The Chloride Homeostasis of CA3 Hippocampal Neurons Is Not Altered in Fully Symptomatic .

Frontiers in cellular neuroscience

Belaïdouni Y, Diabira D, Zhang J, Graziano JC, Bader F, Montheil A, Menuet C, Wayman GA, Gaiarsa JL.
PMID: 34602980
Front Cell Neurosci. 2021 Sep 17;15:724976. doi: 10.3389/fncel.2021.724976. eCollection 2021.

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused mainly by mutations in the

Modeling pluralism and self-regulation explains the emergence of cooperation in networked societies.

Scientific reports

Madeo D, Salvatore S, Mannarini T, Mocenni C.
PMID: 34584146
Sci Rep. 2021 Sep 28;11(1):19226. doi: 10.1038/s41598-021-98524-5.

Understanding the dynamics of cooperative behavior of individuals in complex societies represents a fundamental research question which puzzles scientists working in heterogeneous fields. Many studies have been developed using the unitary agent assumption, which embeds the idea that when...

Men and women waste pickers on landfills in Johannesburg, South Africa: divergence in health, and socioeconomic status.

International archives of occupational and environmental health

Wilson KS, Kootbodien T, Made F, Mdleleni S, Tlotleng N, Ntlebi V, Naicker N.
PMID: 34739598
Int Arch Occup Environ Health. 2021 Nov 05; doi: 10.1007/s00420-021-01787-8. Epub 2021 Nov 05.

OBJECTIVE: To investigate gender differences in health in informal waste pickers affected by poverty and multiple environmental and work hazards.METHODS: A cross-sectional descriptive study was conducted at two major landfill sites in a large city. Information on health, work...

Showing 25 to 36 of 315 entries