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Showing 25 to 36 of 380 entries
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Genome-wide analysis of the human malaria parasite .

Oncotarget

Lima WR, Martins DC, Parreira KS, Scarpelli P, Santos de Moraes M, Topalis P, Hashimoto RF, Garcia CRS.
PMID: 29371963
Oncotarget. 2017 Dec 09;8(69):113987-114001. doi: 10.18632/oncotarget.23053. eCollection 2017 Dec 26.

Little is known about transcription factor regulation during the

Rapid detection of exosomal microRNA biomarkers by electrokinetic concentration for liquid biopsy on chip.

Biomicrofluidics

Cheung LS, Wei X, Martins D, Song YA.
PMID: 30867851
Biomicrofluidics. 2018 Jan 02;12(1):014104. doi: 10.1063/1.5009719. eCollection 2018 Jan.

An ion concentration polarization (ICP)-based electrokinetic concentration device is used for accelerating the surface hybridization reaction between exosomal microRNAs (miRNAs) and morpholinos (MOs) as a synthetic oligo capture probe in the nanomolar concentration range in a microfluidic channel. Compared...

Hydrogen Bonding Regulates the Rigidity of Liposome-Encapsulated Chlorin Photosensitizers.

ChemistryOpen

Vetta M, González L, Nogueira JJ.
PMID: 29938159
ChemistryOpen. 2018 Jun 20;7(6):475-483. doi: 10.1002/open.201800050. eCollection 2018 Jun.

Liposomal formulations facilitate the administration of hydrophobic drugs, avoiding precipitation and aggregation phenomena when injected in polar solvents. The integration of the photosensitizer into the liposome may alter the fluidity of the system and, thus, modify the delivery process...

A group respite pilot project for children with special needs.

Public health nursing (Boston, Mass.)

McGrane C, Masson N, Martins DC.
PMID: 34390040
Public Health Nurs. 2021 Nov;38(6):1009-1014. doi: 10.1111/phn.12957. Epub 2021 Aug 13.

Providing ongoing care for a family member or loved one with special needs is challenging. It is estimated that about 21% of the adult population in the United States are providing unpaid care for loved ones at home. Of...

Glyphosate and AMPA exposure in relation to markers of biological aging in an adult population-based study.

International journal of hygiene and environmental health

Cosemans C, Van Larebeke N, Janssen BG, Martens DS, Baeyens W, Bruckers L, Den Hond E, Coertjens D, Nelen V, Schoeters G, Hoppe HW, Wolfs E, Smeets K, Nawrot TS, Plusquin M.
PMID: 34883335
Int J Hyg Environ Health. 2021 Dec 06;240:113895. doi: 10.1016/j.ijheh.2021.113895. Epub 2021 Dec 06.

BACKGROUND/AIM: Glyphosate, a broad-spectrum herbicide, and its main metabolite aminomethylphosphonic acid (AMPA) are persistent in the environment. Studies showed associations between glyphosate or AMPA exposure and several adverse cellular processes, including metabolic alterations and oxidative stress.OBJECTIVE: To determine the...

Body Composition Variables as Radiographic Biomarkers of Clinical Outcomes in Metastatic Renal Cell Carcinoma Patients Receiving Immune Checkpoint Inhibitors.

Frontiers in oncology

Martini DJ, Olsen TA, Goyal S, Liu Y, Evans ST, Magod B, Brown JT, Yantorni L, Russler GA, Caulfield S, Goldman JM, Nazha B, Kissick HT, Harris WB, Kucuk O, Carthon BC, Master VA, Bilen MA.
PMID: 34307176
Front Oncol. 2021 Jul 09;11:707050. doi: 10.3389/fonc.2021.707050. eCollection 2021.

BACKGROUND: Immune checkpoint inhibitors (ICI) have revolutionized the treatment of metastatic renal cell carcinoma (mRCC). Biomarkers for mRCC patients treated with ICI are limited, and body composition is underutilized in mRCC. We investigated the association between body composition and...

Drone Use for COVID-19 Related Problems: Techno-solutionism and its Societal Implications.

Global policy

Martins BO, Lavallée C, Silkoset A.
PMID: 34899997
Glob Policy. 2021 Nov;12(5):603-612. doi: 10.1111/1758-5899.13007. Epub 2021 Sep 20.

Drones have been widely used by public authorities during the COVID-19 pandemic for pandemic-related problems. As an innovative tool with a wide range of potentialities, they have been deemed suitable for an exceptional situation marked by the persistence of...

Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity.

Scientific reports

Soeiro VS, Silva-Carvalho R, Martins D, Parpot P, Grotto D, Chaud MV, da Gama FMP, Jozala AF.
PMID: 34907234
Sci Rep. 2021 Dec 14;11(1):23944. doi: 10.1038/s41598-021-03264-1.

Nanocomplexes systems made up natural poylymers have pharmacotechnical advantages such as increase of water solubility and a decrease of drugs toxicity. Amphotericin B (AmB) is a drug apply as anti-leishmanial and anti-fungal, however it has low water solubility and...

Molecular insights on ABL kinase activation using tree-based machine learning models and molecular docking.

Molecular diversity

Fernandes PO, Martins DM, de Souza Bozzi A, Martins JPA, de Moraes AH, Maltarollo VG.
PMID: 34191245
Mol Divers. 2021 Aug;25(3):1301-1314. doi: 10.1007/s11030-021-10261-z. Epub 2021 Jun 30.

Abelson kinase (c-Abl) is a non-receptor tyrosine kinase involved in several biological processes essential for cell differentiation, migration, proliferation, and survival. This enzyme's activation might be an alternative strategy for treating diseases such as neutropenia induced by chemotherapy, prostate,...

Resistance to endocrine therapy in HR + and/or HER2 + breast cancer: the most promising predictive biomarkers.

Molecular biology reports

Miranda F, Prazeres H, Mendes F, Martins D, Schmitt F.
PMID: 34739691
Mol Biol Rep. 2022 Jan;49(1):717-733. doi: 10.1007/s11033-021-06863-3. Epub 2021 Nov 05.

Breast cancer is the most common cancer in women. It is a heterogeneous disease, encompassing different biological subtypes that differ in histological features, outcomes, clinical behaviour and different molecular subtypes. Therapy has progressed substantially over the past years with...

Choroid plexus enlargement is associated with neuroinflammation and reduction of blood brain barrier permeability in depression.

NeuroImage. Clinical

Althubaity N, Schubert J, Martins D, Yousaf T, Nettis MA, Mondelli V, Pariante C, Harrison NA, Bullmore ET, Dima D, Turkheimer FE, Veronese M.
PMID: 34972034
Neuroimage Clin. 2021 Dec 27;33:102926. doi: 10.1016/j.nicl.2021.102926. Epub 2021 Dec 27.

BACKGROUND: Recent studies have shown that choroid plexuses (CP) may be involved in the neuro-immune axes, playing a role in the interaction between the central and peripheral inflammation. Here we aimed to investigate CP volume alterations in depression and...

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia.

Oncotarget

Argenziano M, Tortora C, Paola AD, Pota E, Martino MD, Pinto DD, Leva CD, Rossi F.
PMID: 34262648
Oncotarget. 2021 Jul 06;12(14):1377-1387. doi: 10.18632/oncotarget.28000. eCollection 2021 Jul 06.

Pediatric acute myeloid leukemia (AML) represents 20% of total childhood leukemia diagnoses and is characterized by poor prognosis with a long-term survival rate around the 50%, when patients are properly treated. The standard treatment for pediatric AML currently consists...

Showing 25 to 36 of 380 entries