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Showing 1033 to 1040 of 1040 entries
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Targeting citrullination in autoimmunity: insights learned from preclinical mouse models.

Expert opinion on therapeutic targets

Bruggeman Y, Sodré FMC, Buitinga M, Mathieu C, Overbergh L, Kracht MJL.
PMID: 33896351
Expert Opin Ther Targets. 2021 Apr;25(4):269-281. doi: 10.1080/14728222.2021.1918104. Epub 2021 May 04.

INTRODUCTION: Aberrant citrullination and excessive peptidylarginine deiminase (PAD) activity are detected in numerous challenging autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, and type 1 diabetes. Because excessive PAD activity is a common...

Postural orthostatic tachycardia syndrome after surgical correction of an aortic coarctation: a case report.

Journal of medical case reports

Fernex L, Coeytaux A, Rochat T, Karaca S, Perrig S, Burri H, Nendaz MR.
PMID: 22889291
J Med Case Rep. 2012 Aug 13;6:241. doi: 10.1186/1752-1947-6-241.

INTRODUCTION: We report a case of postural tachycardia syndrome occurring after the surgical correction of an aortic coarctation, and coexisting with upper airway resistance syndrome.CASE PRESENTATION: A 29-year-old Caucasian man complained of extreme fatigue, daytime sleepiness, shortness of breath...

Comparing oncological outcomes of laparoscopic vs open radical nephroureterectomy for the treatment of upper tract urothelial carcinoma: A propensity score-matched analysis.

Arab journal of urology

Moschini M, Zamboni S, Afferi L, Pradere B, Abufaraj M, Soria F, D'Andrea D, Roupret M, De la Taille A, Simeone C, Mattei A, Mathieu R, Bensalah K, Wirth MP, Montorsi F, Briganti A, Gallina A, Simone G, Gallucci M, Di Bona C, Marra G, Mari A, Di Trapani E, Alvarez Maestro M, Krajewski W, Shariat SF, Xylinas E, Baumeister P.
PMID: 33763246
Arab J Urol. 2020 Sep 04;19(1):31-36. doi: 10.1080/2090598X.2020.1817720.

OBJECTIVES: To compare oncological outcomes of open (ORNU) and laparoscopic radical nephroureterectomy (LRNU) after controlling for preoperative patient-derived factors.PATIENTS AND METHODS: We evaluated a multi-institutional collaborative database composed of 3984 patients diagnosed with upper tract urothelial carcinoma (UTUC) treated...

KRAS G12C fragment screening renders new binding pockets.

Small GTPases

Mathieu M, Steier V, Fassy F, Delorme C, Papin D, Genet B, Duffieux F, Bertrand T, Delarbre L, Le-Borgne H, Parent A, Didier P, Marquette JP, Lowinski M, Houtmann J, Lamberton A, Debussche L, Alexey R.
PMID: 34558391
Small GTPases. 2022 Jan;13(1):225-238. doi: 10.1080/21541248.2021.1979360. Epub 2021 Sep 24.

KRAS genes belong to the most frequently mutated family of oncogenes in cancer. The G12C mutation, found in a third of lung, half of colorectal and pancreatic cancer cases, is believed to be responsible for a substantial number of...

Overview of the Development and Use of Akt Inhibitors in Prostate Cancer.

Journal of clinical medicine

Gasmi A, Roubaud G, Dariane C, Barret E, Beauval JB, Brureau L, Créhange G, Fiard G, Fromont G, Gauthé M, Ruffion A, Renard-Penna R, Sargos P, Rouprêt M, Ploussard G, Mathieu R.
PMID: 35011901
J Clin Med. 2021 Dec 29;11(1). doi: 10.3390/jcm11010160.

Deregulation of the PI3K-Akt-mTOR pathway plays a critical role in the development and progression of many cancers. In prostate cancer, evidence suggests that it is mainly driven by PTEN loss of function. For many years, the development of selective...

Reprotech in France and the United States: Differences and similarities - An introduction.

Reproductive biomedicine & society online

Mathieu S, Rapp R.
PMID: 33817356
Reprod Biomed Soc Online. 2021 Feb 19;11:106-109. doi: 10.1016/j.rbms.2021.02.001. eCollection 2020 Nov.

No abstract available.

Integrating Research, Teaching and Learning: Preparing the Future National STEM Faculty.

Pfund C, Hooper EJ, Mathieu R.
UIID-AD: 471
2010;431:411-415.

A network of universities (Howard, Michigan State, Texas A&M, University of Colorado at Boulder, University of Wisconsin-Madison, Vanderbilt) have created a National Science Foundation-funded network to prepare a future national STEM (science, technology, engineering, mathematics) faculty committed to learning,...

Learning to Become a More Effective Research or Inquiry-based Project Mentor.

Pfund C, Branchaw J, Hooper EJ, Mathieu R.
UIID-AD: 470
2010;431:247-256.

How effective of a mentor are you? Have you thought much about this question? Have you participated in training to become a better mentor? For many academics, the typical three answers are "pretty good, I think ... why wouldn't...

Showing 1033 to 1040 of 1040 entries