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Showing 13 to 24 of 380 entries
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'AND' logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7.

Scientific reports

Almawi AW, Matthews LA, Larasati, Myrox P, Boulton S, Lai C, Moraes T, Melacini G, Ghirlando R, Duncker BP, Guarné A.
PMID: 27681475
Sci Rep. 2016 Sep 29;6:34237. doi: 10.1038/srep34237.

Forkhead-associated (FHA) domains are phosphopeptide recognition modules found in many signaling proteins. The Saccharomyces cerevisiae protein kinase Rad53 is a key regulator of the DNA damage checkpoint and uses its two FHA domains to interact with multiple binding partners...

Refractory Lactic Acidosis in Small Cell Carcinoma of the Lung.

Case reports in critical care

Oh DJ, Dinerman E, Matthews AH, Aron AW, Berg KM.
PMID: 28620552
Case Rep Crit Care. 2017;2017:6148350. doi: 10.1155/2017/6148350. Epub 2017 May 23.

BACKGROUND: Elevated lactate levels in critically ill patients are most often thought to be indicative of relative tissue hypoxia or type A lactic acidosis. Shock, severe anemia, and thromboembolic events can all cause elevated lactate due to tissue hypoperfusion,...

LAGOS-NE: a multi-scaled geospatial and temporal database of lake ecological context and water quality for thousands of US lakes.

GigaScience

Soranno PA, Bacon LC, Beauchene M, Bednar KE, Bissell EG, Boudreau CK, Boyer MG, Bremigan MT, Carpenter SR, Carr JW, Cheruvelil KS, Christel ST, Claucherty M, Collins SM, Conroy JD, Downing JA, Dukett J, Fergus CE, Filstrup CT, Funk C, Gonzalez MJ, Green LT, Gries C, Halfman JD, Hamilton SK, Hanson PC, Henry EN, Herron EM, Hockings C, Jackson JR, Jacobson-Hedin K, Janus LL, Jones WW, Jones JR, Keson CM, King KBS, Kishbaugh SA, Lapierre JF, Lathrop B, Latimore JA, Lee Y, Lottig NR, Lynch JA, Matthews LJ, McDowell WH, Moore KEB, Neff BP, Nelson SJ, Oliver SK, Pace ML, Pierson DC, Poisson AC, Pollard AI, Post DM, Reyes PO, Rosenberry DO, Roy KM, Rudstam LG, Sarnelle O, Schuldt NJ, Scott CE, Skaff NK, Smith NJ, Spinelli NR, Stachelek JJ, Stanley EH, Stoddard JL, Stopyak SB, Stow CA, Tallant JM, Tan PN, Thorpe AP, Vanni MJ, Wagner T, Watkins G, Weathers KC, Webster KE, White JD, Wilmes MK, Yuan S.
PMID: 29053868
Gigascience. 2017 Dec 01;6(12):1-22. doi: 10.1093/gigascience/gix101.

Understanding the factors that affect water quality and the ecological services provided by freshwater ecosystems is an urgent global environmental issue. Predicting how water quality will respond to global changes not only requires water quality data, but also information...

A Prototype Tool to Enable Farmers to Measure and Improve the Welfare Performance of the Farm Animal Enterprise: The Unified Field Index.

Animals : an open access journal from MDPI

Colditz IG, Ferguson DM, Collins T, Matthews L, Hemsworth PH.
PMID: 26480317
Animals (Basel). 2014 Jul 15;4(3):446-62. doi: 10.3390/ani4030446.

Schemes for the assessment of farm animal welfare and assurance of welfare standards have proliferated in recent years. An acknowledged short-coming has been the lack of impact of these schemes on the welfare standards achieved on farm due in...

Neonatal Brain Tissue Classification with Morphological Adaptation and Unified Segmentation.

Frontiers in neuroinformatics

Beare RJ, Chen J, Kelly CE, Alexopoulos D, Smyser CD, Rogers CE, Loh WY, Matthews LG, Cheong JL, Spittle AJ, Anderson PJ, Doyle LW, Inder TE, Seal ML, Thompson DK.
PMID: 27065840
Front Neuroinform. 2016 Mar 29;10:12. doi: 10.3389/fninf.2016.00012. eCollection 2016.

Measuring the distribution of brain tissue types (tissue classification) in neonates is necessary for studying typical and atypical brain development, such as that associated with preterm birth, and may provide biomarkers for neurodevelopmental outcomes. Compared with magnetic resonance images...

Electrocardiogram derived QRS duration associations with elevated central aortic systolic pressure (CASP) in a rural Australian population.

Clinical hypertension

Lee YY, Reidler P, Jelinek H, Lee YS, Zhou Y, Hambly BD, McCabe J, Matthews S, Ke H, Assareh H, McLachlan CS.
PMID: 26893940
Clin Hypertens. 2016 Feb 16;22:6. doi: 10.1186/s40885-016-0039-8. eCollection 2015.

BACKGROUND: Prolonged electrocardiogram QRS durations are often present in hypertensive patients. Small increases in QRS duration serve as independent risk factors for both increased cardiovascular and all-cause mortality. Aortic stiffness is associated with increases in central aortic systolic blood...

An Internet-Based Study Examining the Factors Associated with the Physical and Mental Health Quality of Life of LGBT Cancer Survivors.

LGBT health

Matthews AK, Hotton A, Li CC, Miller K, Johnson A, Jones KW, Thai J.
PMID: 26789396
LGBT Health. 2016 Feb;3(1):65-73. doi: 10.1089/lgbt.2014.0075. Epub 2015 Aug 26.

PURPOSE: The purpose of this study was to examine factors associated with the quality of life of lesbian, gay, bisexual, and transgender (LGBT) cancer survivors.METHODS: Data were collected via a nationally advertised online short-form health survey.RESULTS: Factors associated with...

Social interactions among captive brushtail possums (Trichosurus vulpecula).

Applied animal behaviour science

Day TD, O'Connor CE, Waas JR, Matthews LR.
PMID: 11080558
Appl Anim Behav Sci. 2000 Dec 01;70(2):157-165. doi: 10.1016/s0168-1591(00)00144-1.

A biological control strategy relying on a self-disseminating agent may provide the only affordable long-term technique for reducing brushtail possum (Trichosurus vulpecula) numbers throughout New Zealand. The objective of this study was to determine the frequency and patterns of...

Diaries of evidence-based tutors: beyond 'numbers needed to teach'.

Journal of evaluation in clinical practice

Elwyn G, Rosenberg W, Edwards A, Chatham W, Jones K, Matthews S, Macbeth F.
PMID: 10970008
J Eval Clin Pract. 2000 May;6(2):149-54. doi: 10.1046/j.1365-2753.2000.00222.x.

Interprofessional evidence-based health care courses have been held throughout the UK over the last few years, modelled on the approach used in McMaster University of using problem-based facilitated small-group formats to achieve the stated goals. Both delegates and tutors...

Cyclic changes in the uterine mucosa of Balaenopterid whales.

Journal of anatomy

Matthews LH.
PMID: 17105061
J Anat. 1948 Oct;82:207-232.4.

No abstract available.

Bad news: is it true?.

Science (New York, N.Y.)

Matthews AF.
PMID: 17817820
Science. 1980 Dec 19;210(4476):1296. doi: 10.1126/science.210.4476.1296-a.

No abstract available.

Embodied environmental emissions in U.S. international trade, 1997-2004.

Environmental science & technology

Weber CL, Matthews HS.
PMID: 17711196
Environ Sci Technol. 2007 Jul 15;41(14):4875-81. doi: 10.1021/es0629110.

Significant recent attention has been given to quantifying the environmental impacts of international trade. However, the United States, despite being the world's largest emitter of greenhouse gases and having large recent growth in international trade, has seen little analysis....

Showing 13 to 24 of 380 entries