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Women receive less targeted temperature management than men following out-of-hospital cardiac arrest due to early care limitations - A study from the CARES Investigators.

Resuscitation

Morris NA, Mazzeffi M, McArdle P, May TL, Burke JF, Bradley SM, Agarwal S, Badjatia N, Perman SM.
PMID: 34756958
Resuscitation. 2021 Dec;169:97-104. doi: 10.1016/j.resuscitation.2021.10.036. Epub 2021 Oct 28.

BACKGROUND: Women experience worse neurological outcomes following out-of-hospital cardiac arrest (OHCA). It is unknown whether sex disparities exist in the use of targeted temperature management (TTM), a standard of care treatment to improve neurological outcomes.METHODS: We performed a retrospective...

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Morris NA, Mazzeffi M, McArdle P, et al. Women receive less targeted temperature management than men following out-of-hospital cardiac arrest due to early care limitations - A study from the CARES Investigators. Resuscitation. 2021;169:97-104doi: 10.1016/j.resuscitation.2021.10.036.
Morris, N. A., Mazzeffi, M., McArdle, P., May, T. L., Burke, J. F., Bradley, S. M., Agarwal, S., Badjatia, N., Perman, S. M. (2021). Women receive less targeted temperature management than men following out-of-hospital cardiac arrest due to early care limitations - A study from the CARES Investigators. Resuscitation, 16997-104. https://doi.org/10.1016/j.resuscitation.2021.10.036
Morris, Nicholas A, et al. "Women receive less targeted temperature management than men following out-of-hospital cardiac arrest due to early care limitations - A study from the CARES Investigators." Resuscitation vol. 169 (2021): 97-104. doi: https://doi.org/10.1016/j.resuscitation.2021.10.036
Morris NA, Mazzeffi M, McArdle P, May TL, Burke JF, Bradley SM, Agarwal S, Badjatia N, Perman SM. Women receive less targeted temperature management than men following out-of-hospital cardiac arrest due to early care limitations - A study from the CARES Investigators. Resuscitation. 2021 Dec;169:97-104. doi: 10.1016/j.resuscitation.2021.10.036. Epub 2021 Oct 28. PMID: 34756958.
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The BiZiFED project: Biofortified zinc flour to eliminate deficiency in Pakistan.

Nutrition bulletin

Ohly H, Broadley MR, Joy EJM, Khan MJ, McArdle H, Zaman M, Zia M, Lowe N.
PMID: 31217749
Nutr Bull. 2019 Mar;44(1):60-64. doi: 10.1111/nbu.12362. Epub 2019 Jan 17.

Zinc deficiency is a global public health problem, affecting ~17% of the world's population, with the greatest burden in low- and middle-income countries. An increasing body of evidence suggests that biofortification may be a cost-effective and sustainable approach to...

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Ohly H, Broadley MR, Joy EJM, et al. The BiZiFED project: Biofortified zinc flour to eliminate deficiency in Pakistan. Nutr Bull. 2019;44(1):60-64doi: 10.1111/nbu.12362.
Ohly, H., Broadley, M. R., Joy, E. J. M., Khan, M. J., McArdle, H., Zaman, M., Zia, M., & Lowe, N. (2019). The BiZiFED project: Biofortified zinc flour to eliminate deficiency in Pakistan. Nutrition bulletin, 44(1), 60-64. https://doi.org/10.1111/nbu.12362
Ohly, H, et al. "The BiZiFED project: Biofortified zinc flour to eliminate deficiency in Pakistan." Nutrition bulletin vol. 44,1 (2019): 60-64. doi: https://doi.org/10.1111/nbu.12362
Ohly H, Broadley MR, Joy EJM, Khan MJ, McArdle H, Zaman M, Zia M, Lowe N. The BiZiFED project: Biofortified zinc flour to eliminate deficiency in Pakistan. Nutr Bull. 2019 Mar;44(1):60-64. doi: 10.1111/nbu.12362. Epub 2019 Jan 17. PMID: 31217749; PMCID: PMC6559288.
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Nicolaides-Baraitser syndrome in a patient with hypertrophic cardiomyopathy and .

Cardiology in the young

Foley R, Duignan S, McArdle L, Betts DR, Green A, McMahon CJ.
PMID: 34521483
Cardiol Young. 2021 Sep 15;1-3. doi: 10.1017/S1047951121003826. Epub 2021 Sep 15.

Nicolaides-Baraitser syndrome is a rare, neuro-developmental disorder caused by heterozygous pathogenic variants in the SMARCA2 gene, involved with chromatin regulation. Cardinal features include intellectual disability, short stature, microcephaly, triangular facies, sparse hair, brachydactyly, prominent interphalangeal joints and seizures. Genetic...

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Foley R, Duignan S, McArdle L, et al. Nicolaides-Baraitser syndrome in a patient with hypertrophic cardiomyopathy and . Cardiol Young. 2021;1-3doi: 10.1017/S1047951121003826.
Foley, R., Duignan, S., McArdle, L., Betts, D. R., Green, A., & McMahon, C. J. (2021). Nicolaides-Baraitser syndrome in a patient with hypertrophic cardiomyopathy and . Cardiology in the young, 1-3. https://doi.org/10.1017/S1047951121003826
Foley, Ross, et al. "Nicolaides-Baraitser syndrome in a patient with hypertrophic cardiomyopathy and ." Cardiology in the young vol. (2021): 1-3. doi: https://doi.org/10.1017/S1047951121003826
Foley R, Duignan S, McArdle L, Betts DR, Green A, McMahon CJ. Nicolaides-Baraitser syndrome in a patient with hypertrophic cardiomyopathy and . Cardiol Young. 2021 Sep 15;1-3. doi: 10.1017/S1047951121003826. Epub 2021 Sep 15. PMID: 34521483.
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Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy.

STAR protocols

Fan Z, Mikulski Z, McArdle S, Sundd P, Ley K.
PMID: 33111071
STAR Protoc. 2020 Jun 03;1(1):100012. doi: 10.1016/j.xpro.2019.100012. eCollection 2020 Jun 19.

This protocol introduces the SuperSTORM technique, combining stochastic optical reconstruction microscopy (STORM) and molecular modeling. SuperSTORM is optimized for acquiring and processing STORM images of neutrophil integrins but can be used for any cell-surface molecule with known structure and...

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Fan Z, Mikulski Z, McArdle S, et al. Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy. STAR Protoc. 2020;1(1):100012doi: 10.1016/j.xpro.2019.100012.
Fan, Z., Mikulski, Z., McArdle, S., Sundd, P., & Ley, K. (2020). Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy. STAR protocols, 1(1), 100012. https://doi.org/10.1016/j.xpro.2019.100012
Fan, Zhichao, et al. "Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy." STAR protocols vol. 1,1 (2020): 100012. doi: https://doi.org/10.1016/j.xpro.2019.100012
Fan Z, Mikulski Z, McArdle S, Sundd P, Ley K. Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy. STAR Protoc. 2020 Jun 03;1(1):100012. doi: 10.1016/j.xpro.2019.100012. eCollection 2020 Jun 19. PMID: 33111071; PMCID: PMC7580203.
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Volumetric magnetic resonance imaging analysis of multilevel upper airway surgery effects on pharyngeal structure.

Sleep

Sutherland K, Lowth AB, Antic N, Carney AS, Catcheside PG, Chai-Coetzer CL, Chia M, Hodge JC, Jones A, Kaambwa B, Lewis R, MacKay S, McEvoy RD, Ooi EH, Pinczel AJ, McArdle N, Rees G, Singh B, Stow N, Weaver EM, Woodman RJ, Woods CM, Yeo A, Cistulli PA.
PMID: 34283220
Sleep. 2021 Dec 10;44(12). doi: 10.1093/sleep/zsab183.

STUDY OBJECTIVES: The Sleep Apnea Multilevel Surgery (SAMS) trial found that modified uvulopalatopharyngoplasty with tonsillectomy (if tonsils present) combined with radiofrequency tongue ablation reduced obstructive sleep apnea (OSA) severity and daytime sleepiness in moderate-severe OSA. This study aimed to...

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Sutherland K, Lowth AB, Antic N, et al. Volumetric magnetic resonance imaging analysis of multilevel upper airway surgery effects on pharyngeal structure. Sleep. 2021;44(12)doi: 10.1093/sleep/zsab183.
Sutherland, K., Lowth, A. B., Antic, N., Carney, A. S., Catcheside, P. G., Chai-Coetzer, C. L., Chia, M., Hodge, J. C., Jones, A., Kaambwa, B., Lewis, R., MacKay, S., McEvoy, R. D., Ooi, E. H., Pinczel, A. J., McArdle, N., Rees, G., Singh, B., Stow, N., Weaver, E. M., Woodman, R. J., Woods, C. M., Yeo, A., & Cistulli, P. A. (2021). Volumetric magnetic resonance imaging analysis of multilevel upper airway surgery effects on pharyngeal structure. Sleep, 44(12), . https://doi.org/10.1093/sleep/zsab183
Sutherland, Kate, et al. "Volumetric magnetic resonance imaging analysis of multilevel upper airway surgery effects on pharyngeal structure." Sleep vol. 44,12 (2021). doi: https://doi.org/10.1093/sleep/zsab183
Sutherland K, Lowth AB, Antic N, Carney AS, Catcheside PG, Chai-Coetzer CL, Chia M, Hodge JC, Jones A, Kaambwa B, Lewis R, MacKay S, McEvoy RD, Ooi EH, Pinczel AJ, McArdle N, Rees G, Singh B, Stow N, Weaver EM, Woodman RJ, Woods CM, Yeo A, Cistulli PA. Volumetric magnetic resonance imaging analysis of multilevel upper airway surgery effects on pharyngeal structure. Sleep. 2021 Dec 10;44(12). doi: 10.1093/sleep/zsab183. PMID: 34283220; PMCID: PMC8664571.
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Prostate cancer: Important steps and considerations in the design of therapeutic vaccines.

Oncoimmunology

McArdle SE, Pockley AG, Gibson GR, Rees RC.
PMID: 25340006
Oncoimmunology. 2014 Feb 14;3:e28049. doi: 10.4161/onci.28049. eCollection 2014.

Vaccine-based immunotherapy can increase the overall survival of patients with advanced prostate cancer. However, the efficacy of vaccine-elicited anticancer immune responses is heavily influenced by the physical, nutritional, and psychological status of the patient. Given their importance, these parameters...

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McArdle SE, Pockley AG, Gibson GR, et al. Prostate cancer: Important steps and considerations in the design of therapeutic vaccines. Oncoimmunology. 2014;3:e28049doi: 10.4161/onci.28049.
McArdle, S. E., Pockley, A. G., Gibson, G. R., & Rees, R. C. (2014). Prostate cancer: Important steps and considerations in the design of therapeutic vaccines. Oncoimmunology, 3e28049. https://doi.org/10.4161/onci.28049
McArdle, Stephanie Eb, et al. "Prostate cancer: Important steps and considerations in the design of therapeutic vaccines." Oncoimmunology vol. 3 (2014): e28049. doi: https://doi.org/10.4161/onci.28049
McArdle SE, Pockley AG, Gibson GR, Rees RC. Prostate cancer: Important steps and considerations in the design of therapeutic vaccines. Oncoimmunology. 2014 Feb 14;3:e28049. doi: 10.4161/onci.28049. eCollection 2014. PMID: 25340006; PMCID: PMC4203569.
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Donor properties of the vanadyl ion: reactions of vanadyl salicylaldimine beta-ketimine and acetylacetonato complexes with groups 14 and 15 Lewis acids.

Inorganic chemistry

Cashin B, Cunningham D, Daly P, McArdle P, Munroe M, Ní Chonchubhair N.
PMID: 11849077
Inorg Chem. 2002 Feb 25;41(4):773-82. doi: 10.1021/ic010366s.

Reactions of organosilicon, -germanium, -tin, -lead, -antimony, and -tin tetrahalide Lewis acids with VO(salen) [H(2)salen = N,N'-bis(salicylidene)ethane-1,2-diamine], related vanadyl salicylaldimines, VO(acacen) [H(2)acacen = N,N'-bis(acetylacetonato)ethane-1,2-diamine], and VO(acac)(2) (acac = acetylacetonato) have been investigated, revealing VO(salen) and VO(acacen) to be significantly...

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Cashin B, Cunningham D, Daly P, et al. Donor properties of the vanadyl ion: reactions of vanadyl salicylaldimine beta-ketimine and acetylacetonato complexes with groups 14 and 15 Lewis acids. Inorg Chem. 2002;41(4):773-82doi: 10.1021/ic010366s.
Cashin, B., Cunningham, D., Daly, P., McArdle, P., Munroe, M., & Ní Chonchubhair, N. (2002). Donor properties of the vanadyl ion: reactions of vanadyl salicylaldimine beta-ketimine and acetylacetonato complexes with groups 14 and 15 Lewis acids. Inorganic chemistry, 41(4), 773-82. https://doi.org/10.1021/ic010366s
Cashin, B, et al. "Donor properties of the vanadyl ion: reactions of vanadyl salicylaldimine beta-ketimine and acetylacetonato complexes with groups 14 and 15 Lewis acids." Inorganic chemistry vol. 41,4 (2002): 773-82. doi: https://doi.org/10.1021/ic010366s
Cashin B, Cunningham D, Daly P, McArdle P, Munroe M, Ní Chonchubhair N. Donor properties of the vanadyl ion: reactions of vanadyl salicylaldimine beta-ketimine and acetylacetonato complexes with groups 14 and 15 Lewis acids. Inorg Chem. 2002 Feb 25;41(4):773-82. doi: 10.1021/ic010366s. PMID: 11849077.
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Gold(I) macrocycles and topologically chiral [2]catenanes.

Journal of the American Chemical Society

McArdle CP, Van S, Jennings MC, Puddephatt RJ.
PMID: 11942834
J Am Chem Soc. 2002 Apr 17;124(15):3959-65. doi: 10.1021/ja012006+.

The design and synthesis of a new type of topologically chiral [2]catenane is reported. The compounds are formed easily by self-assembly on reaction of the oligomeric digold(I) diacetylide precursor complex [[4-BrC(6)H(4)CH(4-C(6)H(4)OCH(2)CCAu)(2)](n)] with diphosphine ligands. Reactions with the diphosphines PP...

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McArdle CP, Van S, Jennings MC, et al. Gold(I) macrocycles and topologically chiral [2]catenanes. J Am Chem Soc. 2002;124(15):3959-65doi: 10.1021/ja012006+.
McArdle, C. P., Van, S., Jennings, M. C., & Puddephatt, R. J. (2002). Gold(I) macrocycles and topologically chiral [2]catenanes. Journal of the American Chemical Society, 124(15), 3959-65. https://doi.org/10.1021/ja012006+
McArdle, Christopher P, et al. "Gold(I) macrocycles and topologically chiral [2]catenanes." Journal of the American Chemical Society vol. 124,15 (2002): 3959-65. doi: https://doi.org/10.1021/ja012006+
McArdle CP, Van S, Jennings MC, Puddephatt RJ. Gold(I) macrocycles and topologically chiral [2]catenanes. J Am Chem Soc. 2002 Apr 17;124(15):3959-65. doi: 10.1021/ja012006+. PMID: 11942834.
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Stereoselective Epimerizations of Glycosyl Thiols.

Organic letters

Doyle LM, O'Sullivan S, Di Salvo C, McKinney M, McArdle P, Murphy PV.
PMID: 29039672
Org Lett. 2017 Nov 03;19(21):5802-5805. doi: 10.1021/acs.orglett.7b02760.

Glycosyl thiols are widely used in stereoselective S-glycoside synthesis. Their epimerization from 1,2-trans to 1,2-cis thiols (e.g., equatorial to axial epimerization in thioglucopyranose) was attained using TiCl

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Doyle LM, O'Sullivan S, Di Salvo C, et al. Stereoselective Epimerizations of Glycosyl Thiols. Org Lett. 2017;19(21):5802-5805doi: 10.1021/acs.orglett.7b02760.
Doyle, L. M., O'Sullivan, S., Di Salvo, C., McKinney, M., McArdle, P., & Murphy, P. V. (2017). Stereoselective Epimerizations of Glycosyl Thiols. Organic letters, 19(21), 5802-5805. https://doi.org/10.1021/acs.orglett.7b02760
Doyle, Lisa M, et al. "Stereoselective Epimerizations of Glycosyl Thiols." Organic letters vol. 19,21 (2017): 5802-5805. doi: https://doi.org/10.1021/acs.orglett.7b02760
Doyle LM, O'Sullivan S, Di Salvo C, McKinney M, McArdle P, Murphy PV. Stereoselective Epimerizations of Glycosyl Thiols. Org Lett. 2017 Nov 03;19(21):5802-5805. doi: 10.1021/acs.orglett.7b02760. PMID: 29039672.
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Ovarian function after chemotherapy in young breast cancer survivors.

Current oncology (Toronto, Ont.)

Morarji K, McArdle O, Hui K, Gingras-Hill G, Ahmed S, Greenblatt EM, Warner E, Sridhar S, Ali AMF, Azad A, Hodgson DC.
PMID: 29270058
Curr Oncol. 2017 Dec;24(6):e494-e502. doi: 10.3747/co.24.3335. Epub 2017 Dec 20.

BACKGROUND: As cure rates for breast cancer improve, there is increasing evidence that late effects of treatment-and impaired fertility in particular-are emerging as important concerns among young breast cancer survivors. Older reports have evaluated the occurrence of amenorrhea after...

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Morarji K, McArdle O, Hui K, et al. Ovarian function after chemotherapy in young breast cancer survivors. Curr Oncol. 2017;24(6):e494-e502doi: 10.3747/co.24.3335.
Morarji, K., McArdle, O., Hui, K., Gingras-Hill, G., Ahmed, S., Greenblatt, E. M., Warner, E., Sridhar, S., Ali, A. M. F., Azad, A., & Hodgson, D. C. (2017). Ovarian function after chemotherapy in young breast cancer survivors. Current oncology (Toronto, Ont.), 24(6), e494-e502. https://doi.org/10.3747/co.24.3335
Morarji, K, et al. "Ovarian function after chemotherapy in young breast cancer survivors." Current oncology (Toronto, Ont.) vol. 24,6 (2017): e494-e502. doi: https://doi.org/10.3747/co.24.3335
Morarji K, McArdle O, Hui K, Gingras-Hill G, Ahmed S, Greenblatt EM, Warner E, Sridhar S, Ali AMF, Azad A, Hodgson DC. Ovarian function after chemotherapy in young breast cancer survivors. Curr Oncol. 2017 Dec;24(6):e494-e502. doi: 10.3747/co.24.3335. Epub 2017 Dec 20. PMID: 29270058; PMCID: PMC5736488.
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Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention.

Toxicology reports

Nasi A, McArdle S, Gaudernack G, Westman G, Melief C, Rockberg J, Arens R, Kouretas D, Sjölin J, Mangsbo S.
PMID: 32632359
Toxicol Rep. 2020 Jun 18;7:768-771. doi: 10.1016/j.toxrep.2020.06.003. eCollection 2020.

During the current COVID-19 pandemic, a need for evaluation of already available drugs for treatment of the disease is crucial. Hereby, based on literature review from the current pandemic and previous outbreaks with corona viruses we analyze the impact...

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Nasi A, McArdle S, Gaudernack G, et al. Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention. Toxicol Rep. 2020;7:768-771doi: 10.1016/j.toxrep.2020.06.003.
Nasi, A., McArdle, S., Gaudernack, G., Westman, G., Melief, C., Rockberg, J., Arens, R., Kouretas, D., Sjölin, J., & Mangsbo, S. (2020). Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention. Toxicology reports, 7768-771. https://doi.org/10.1016/j.toxrep.2020.06.003
Nasi, Aikaterini, et al. "Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention." Toxicology reports vol. 7 (2020): 768-771. doi: https://doi.org/10.1016/j.toxrep.2020.06.003
Nasi A, McArdle S, Gaudernack G, Westman G, Melief C, Rockberg J, Arens R, Kouretas D, Sjölin J, Mangsbo S. Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention. Toxicol Rep. 2020 Jun 18;7:768-771. doi: 10.1016/j.toxrep.2020.06.003. eCollection 2020. PMID: 32632359; PMCID: PMC7301821.
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Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources.

EFSA journal. European Food Safety Authority

, Younes M, Aggett P, Aguilar F, Crebelli R, Dusemund B, Filipicč M, Frutos MJ, Galtier P, Gundert-Remy U, Kuhnle GG, Lambré C, Leblanc JC, Lillegaard IT, Moldeus P, Mortensen A, Oskarsson A, Stankovic I, Waalkens-Berendsen I, Woutersen RA, Wright M, Di Domenico A, Fairweather-Tait S, McArdle H, Smeraldi C, Gott D.
PMID: 32625933
EFSA J. 2018 Jun 26;16(6):e05294. doi: 10.2903/j.efsa.2018.5294. eCollection 2018 Jun.

Whenever new substances are proposed for use as sources of nutrients in food supplements, foods for the general population or foods for specific groups, EFSA is requested by the European Commission to perform an assessment of their safety and...

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, Younes M, Aggett P, et al. Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources. EFSA J. 2018;16(6):e05294doi: 10.2903/j.efsa.2018.5294.
, Younes, M., Aggett, P., Aguilar, F., Crebelli, R., Dusemund, B., Filipicč, M., Frutos, M. J., Galtier, P., Gundert-Remy, U., Kuhnle, G. G., Lambré, C., Leblanc, J. C., Lillegaard, I. T., Moldeus, P., Mortensen, A., Oskarsson, A., Stankovic, I., Waalkens-Berendsen, I., Woutersen, R. A., Wright, M., Di Domenico, A., Fairweather-Tait, S., McArdle, H., Smeraldi, C., & Gott, D. (2018). Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources. EFSA journal. European Food Safety Authority, 16(6), e05294. https://doi.org/10.2903/j.efsa.2018.5294
, et al. "Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources." EFSA journal. European Food Safety Authority vol. 16,6 (2018): e05294. doi: https://doi.org/10.2903/j.efsa.2018.5294
, Younes M, Aggett P, Aguilar F, Crebelli R, Dusemund B, Filipicč M, Frutos MJ, Galtier P, Gundert-Remy U, Kuhnle GG, Lambré C, Leblanc JC, Lillegaard IT, Moldeus P, Mortensen A, Oskarsson A, Stankovic I, Waalkens-Berendsen I, Woutersen RA, Wright M, Di Domenico A, Fairweather-Tait S, McArdle H, Smeraldi C, Gott D. Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources. EFSA J. 2018 Jun 26;16(6):e05294. doi: 10.2903/j.efsa.2018.5294. eCollection 2018 Jun. PMID: 32625933; PMCID: PMC7009562.
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Showing 25 to 36 of 201 entries