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Showing 817 to 825 of 825 entries
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An institutional audit of the use of novel drugs in pediatric oncology.

Cancer reports (Hoboken, N.J.)

Lee J, Gillam L, Kouw S, McCarthy MC, Hansford JR.
PMID: 33939320
Cancer Rep (Hoboken). 2021 Dec;4(6):e1404. doi: 10.1002/cnr2.1404. Epub 2021 May 03.

BACKGROUND: Significant challenges persist in treating children with rare, relapsed, or refractory malignancies. Novel molecularly targeted drugs promise improved outcomes for these children with reduced toxicity. However, there is often limited evidence to substantiate their clinical efficacy and guide...

Intraoperative image guidance for lateral position surgery.

Annals of translational medicine

Swiatek PR, McCarthy MH, Weiner J, Bhargava S, Vaishnav AS, Iyer S.
PMID: 33553383
Ann Transl Med. 2021 Jan;9(1):90. doi: 10.21037/atm-2020-ioi-10.

Recent advances in minimally invasive spine surgery techniques have precipitated the popularity of lateral position spine surgery, such as lateral lumbar interbody fusion (LLIF) and oblique lumbar interbody fusion (OLIF). Lateral position surgery offers a unique, minimally invasive approach...

Care coordination needs for deprescribing benzodiazepines and benzodiazepine receptor agonists.

Research in social & administrative pharmacy : RSAP

McCarthy M, Mak S, Kaufmann CN, Lum HD, Fung CH.
PMID: 34229951
Res Social Adm Pharm. 2021 Jul 01; doi: 10.1016/j.sapharm.2021.06.025. Epub 2021 Jul 01.

Deprescribing of medications such as benzodiazepines and benzodiazepine receptor agonists (z-drugs) can be a complex process that varies across practices, specialties, and health care systems. Care coordination among healthcare providers, patients, families, and other healthcare system components is critical...

Analysis of the Cellular and Matrix Composition of Subacromial Bursal Tissue.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

Levy BJ, McCarthy MB, Lebaschi A, Sanders MM, Cote MP, Mazzocca AD.
PMID: 34767955
Arthroscopy. 2021 Nov 10; doi: 10.1016/j.arthro.2021.10.029. Epub 2021 Nov 10.

PURPOSE: To build upon previous literature to identify a complete analysis of cellular contents of subacromial bursal tissue as well as the matrix surrounding the rotator cuff.METHODS: Samples of subacromial bursal tissue and surrounding matrix milieu from above the...

Laboratory-based dried blood spot testing for hepatitis C: A protocol for systematic review and meta-analysis of diagnostic accuracy.

HRB open research

Carty PG, McCarthy M, O'Neill S, Harrington P, O'Neill M, Teljeur C, Smith SM, Ryan M.
PMID: 34957372
HRB Open Res. 2020 Oct 27;3:78. doi: 10.12688/hrbopenres.13166.1. eCollection 2020.

No abstract available.

Social behavior in prepubertal neurexin 1α deficient rats: A model of neurodevelopmental disorders.

Behavioral neuroscience

Kight KE, Argue KJ, Bumgardner JG, Bardhi K, Waddell J, McCarthy MM.
PMID: 34323517
Behav Neurosci. 2021 Dec;135(6):782-803. doi: 10.1037/bne0000482. Epub 2021 Jul 29.

Loss-of-function mutations in the synaptic protein neurexin1α (NRXN1α) are associated with several neurodevelopmental disorders, including autism spectrum disorder (ASD), schizophrenia, and attention-deficit hyperactivity disorder (ADHD), and many of these disorders are defined by core deficits in social cognition. Mouse...

Validation of Breast Cancer Risk Models by Race/Ethnicity, Family History and Molecular Subtypes.

Cancers

McCarthy AM, Liu Y, Ehsan S, Guan Z, Liang J, Huang T, Hughes K, Semine A, Kontos D, Conant E, Lehman C, Armstrong K, Braun D, Parmigiani G, Chen J.
PMID: 35008209
Cancers (Basel). 2021 Dec 23;14(1). doi: 10.3390/cancers14010045.

(1) Background: The purpose of this study is to compare the performance of four breast cancer risk prediction models by race, molecular subtype, family history of breast cancer, age, and BMI. (2) Methods: Using a cohort of women aged...

Longitudinal Prevalence of Antibodies to Endemic Pathogens in Bulk Tank Milk Samples From Dairy Herds Engaged or Not in Contract Heifer Rearing.

Frontiers in veterinary science

McCarthy MC, O'Grady L, McAloon CG, Mee JF.
PMID: 34901254
Front Vet Sci. 2021 Nov 25;8:785128. doi: 10.3389/fvets.2021.785128. eCollection 2021.

Since the abolition of EU milk production quotas in 2015, Europe's dairy industries have undergone a period of rapid expansion with possible resultant increased inter-herd transmission of endemic pathogens. The aims of this study were (1) to establish the...

Evaluation of GeneXpert PA assay compared to genomic and (semi-)quantitative culture methods for direct detection of Pseudomonas aeruginosa in endotracheal aspirates.

Antimicrobial resistance and infection control

van der Schalk TE, Coppens J, Timbermont L, Turlej-Rogacka A, Van Heirstraeten L, Berkell M, Yu L, Lammens C, Xavier BB, Matheeussen V, Ieven M, McCarthy M, Jorens PG, Ruzin A, Esser MT, Kumar-Singh S, Goossens H, Malhotra-Kumar S.
PMID: 34301343
Antimicrob Resist Infect Control. 2021 Jul 23;10(1):110. doi: 10.1186/s13756-021-00978-9.

INTRODUCTION: Pseudomonas aeruginosa is a common cause of ventilator-associated pneumonia (VAP). Rapid and accurate detection of lower respiratory tract colonization and/or infection with P. aeruginosa may advise targeted preventive (antibody-based) strategies and antibiotic therapy. To investigate this, we compared...

Showing 817 to 825 of 825 entries