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Showing 193 to 203 of 203 entries
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Update to coagulopathy in COVID-19: Manifestations and management.

Cleveland Clinic journal of medicine

Mucha SR, Dugar S, McCrae K, Joseph D, Bartholomew J, Sacha GL, Militello M.
PMID: 33323363
Cleve Clin J Med. 2021 Jun 02; doi: 10.3949/ccjm.87a.ccc024-up. Epub 2021 Jun 02.

Severe COVID-19 illness is associated with intense inflammation, leading to high rates of thrombotic complications that increase morbidity and mortality. Markedly elevated levels of D-dimer with normal fibrinogen levels are the hallmark laboratory findings of severe COVID-19-associated coagulopathy. Prophylaxis...

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Mucha SR, Dugar S, McCrae K, et al. Update to coagulopathy in COVID-19: Manifestations and management. Cleve Clin J Med. 2021;doi: 10.3949/ccjm.87a.ccc024-up.
Mucha, S. R., Dugar, S., McCrae, K., Joseph, D., Bartholomew, J., Sacha, G. L., & Militello, M. (2021). Update to coagulopathy in COVID-19: Manifestations and management. Cleveland Clinic journal of medicine, . https://doi.org/10.3949/ccjm.87a.ccc024-up
Mucha, Simon R, et al. "Update to coagulopathy in COVID-19: Manifestations and management." Cleveland Clinic journal of medicine vol. (2021). doi: https://doi.org/10.3949/ccjm.87a.ccc024-up
Mucha SR, Dugar S, McCrae K, Joseph D, Bartholomew J, Sacha GL, Militello M. Update to coagulopathy in COVID-19: Manifestations and management. Cleve Clin J Med. 2021 Jun 02; doi: 10.3949/ccjm.87a.ccc024-up. Epub 2021 Jun 02. PMID: 33323363.
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Smooth muscle cells affect differential nanoparticle accumulation in disturbed blood flow-induced murine atherosclerosis.

PloS one

Miller HA, Schake MA, Bony BA, Curtis ET, Gee CC, McCue IS, Ripperda TJ, Chatzizisis YS, Kievit FM, Pedrigi RM.
PMID: 34882722
PLoS One. 2021 Dec 09;16(12):e0260606. doi: 10.1371/journal.pone.0260606. eCollection 2021.

Atherosclerosis is a lipid-driven chronic inflammatory disease that leads to the formation of plaques in the inner lining of arteries. Plaques form over a range of phenotypes, the most severe of which is vulnerable to rupture and causes most...

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Miller HA, Schake MA, Bony BA, et al. Smooth muscle cells affect differential nanoparticle accumulation in disturbed blood flow-induced murine atherosclerosis. PLoS One. 2021;16(12):e0260606doi: 10.1371/journal.pone.0260606.
Miller, H. A., Schake, M. A., Bony, B. A., Curtis, E. T., Gee, C. C., McCue, I. S., Ripperda, T. J., Chatzizisis, Y. S., Kievit, F. M., & Pedrigi, R. M. (2021). Smooth muscle cells affect differential nanoparticle accumulation in disturbed blood flow-induced murine atherosclerosis. PloS one, 16(12), e0260606. https://doi.org/10.1371/journal.pone.0260606
Miller, Hunter A, et al. "Smooth muscle cells affect differential nanoparticle accumulation in disturbed blood flow-induced murine atherosclerosis." PloS one vol. 16,12 (2021): e0260606. doi: https://doi.org/10.1371/journal.pone.0260606
Miller HA, Schake MA, Bony BA, Curtis ET, Gee CC, McCue IS, Ripperda TJ, Chatzizisis YS, Kievit FM, Pedrigi RM. Smooth muscle cells affect differential nanoparticle accumulation in disturbed blood flow-induced murine atherosclerosis. PLoS One. 2021 Dec 09;16(12):e0260606. doi: 10.1371/journal.pone.0260606. eCollection 2021. PMID: 34882722; PMCID: PMC8659666.
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Social Stressors, Arboviral Infection, and Immune Dysregulation in the Coastal Lowland Region of Ecuador: A Mixed Methods Approach in Ecological Perspective.

The American journal of tropical medicine and hygiene

Vega Ocasio D, Stewart-Ibarra AM, Sippy R, Li C, McCue K, Bendinskas KG, Gump BB, Cueva-Aponte C, Ayala EB, Morrell CN, Dye TD.
PMID: 34339390
Am J Trop Med Hyg. 2021 Aug 02; doi: 10.4269/ajtmh.20-1625. Epub 2021 Aug 02.

Aedes aegypti, the mosquito that transmits arboviral diseases such as dengue (DENV), chikungunya (CHIKV), and Zika viruses (ZIKV), is present in tropical and subtropical regions of the world. Individuals at risk of mosquito-borne disease (MBD) in the urban tropics...

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Vega Ocasio D, Stewart-Ibarra AM, Sippy R, et al. Social Stressors, Arboviral Infection, and Immune Dysregulation in the Coastal Lowland Region of Ecuador: A Mixed Methods Approach in Ecological Perspective. Am J Trop Med Hyg. 2021;doi: 10.4269/ajtmh.20-1625.
Vega Ocasio, D., Stewart-Ibarra, A. M., Sippy, R., Li, C., McCue, K., Bendinskas, K. G., Gump, B. B., Cueva-Aponte, C., Ayala, E. B., Morrell, C. N., & Dye, T. D. (2021). Social Stressors, Arboviral Infection, and Immune Dysregulation in the Coastal Lowland Region of Ecuador: A Mixed Methods Approach in Ecological Perspective. The American journal of tropical medicine and hygiene, . https://doi.org/10.4269/ajtmh.20-1625
Vega Ocasio, Denisse, et al. "Social Stressors, Arboviral Infection, and Immune Dysregulation in the Coastal Lowland Region of Ecuador: A Mixed Methods Approach in Ecological Perspective." The American journal of tropical medicine and hygiene vol. (2021). doi: https://doi.org/10.4269/ajtmh.20-1625
Vega Ocasio D, Stewart-Ibarra AM, Sippy R, Li C, McCue K, Bendinskas KG, Gump BB, Cueva-Aponte C, Ayala EB, Morrell CN, Dye TD. Social Stressors, Arboviral Infection, and Immune Dysregulation in the Coastal Lowland Region of Ecuador: A Mixed Methods Approach in Ecological Perspective. Am J Trop Med Hyg. 2021 Aug 02; doi: 10.4269/ajtmh.20-1625. Epub 2021 Aug 02. PMID: 34339390; PMCID: PMC8592363.
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Apremilast in a Japanese subgroup with Behçet's syndrome: Results from a Phase 3, randomised, double-blind, placebo-controlled study.

Modern rheumatology

Takeno M, Dobashi H, Tanaka Y, Kono H, Sugii S, Kishimoto M, Cheng S, McCue S, Paris M, Chen M, Ishigatsubo Y.
PMID: 34894266
Mod Rheumatol. 2021 Aug 12; doi: 10.1093/mr/roab008. Epub 2021 Aug 12.

OBJECTIVES: Apremilast efficacy and safety was assessed in a prespecified subgroup of Japanese patients with oral ulcers associated with Behçet's syndrome from a Phase 3 randomized, placebo-controlled, double-blind study of apremilast (RELIEF).METHODS: The primary end point was area under...

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Takeno M, Dobashi H, Tanaka Y, et al. Apremilast in a Japanese subgroup with Behçet's syndrome: Results from a Phase 3, randomised, double-blind, placebo-controlled study. Mod Rheumatol. 2021;doi: 10.1093/mr/roab008.
Takeno, M., Dobashi, H., Tanaka, Y., Kono, H., Sugii, S., Kishimoto, M., Cheng, S., McCue, S., Paris, M., Chen, M., & Ishigatsubo, Y. (2021). Apremilast in a Japanese subgroup with Behçet's syndrome: Results from a Phase 3, randomised, double-blind, placebo-controlled study. Modern rheumatology, . https://doi.org/10.1093/mr/roab008
Takeno, Mitsuhiro, et al. "Apremilast in a Japanese subgroup with Behçet's syndrome: Results from a Phase 3, randomised, double-blind, placebo-controlled study." Modern rheumatology vol. (2021). doi: https://doi.org/10.1093/mr/roab008
Takeno M, Dobashi H, Tanaka Y, Kono H, Sugii S, Kishimoto M, Cheng S, McCue S, Paris M, Chen M, Ishigatsubo Y. Apremilast in a Japanese subgroup with Behçet's syndrome: Results from a Phase 3, randomised, double-blind, placebo-controlled study. Mod Rheumatol. 2021 Aug 12; doi: 10.1093/mr/roab008. Epub 2021 Aug 12. PMID: 34894266.
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Safely resuming neglected tropical disease control activities during COVID-19: Perspectives from Nigeria and Guinea.

PLoS neglected tropical diseases

McKay S, Shu'aibu J, Cissé A, Knight A, Abdullahi F, Ibrahim A, Madaki S, Genovezos C, McCoy K, Downs P, Kabore A, Adamu H, Gobir IB, Chaitkin M, Standley CJ.
PMID: 34928945
PLoS Negl Trop Dis. 2021 Dec 20;15(12):e0009904. doi: 10.1371/journal.pntd.0009904. eCollection 2021 Dec.

Since its early spread in early 2020, the disease caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Coronavirus Disease 2019 (COVID-19) has caused mass disruptions to health services. These have included interruptions to programs that aimed...

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McKay S, Shu'aibu J, Cissé A, et al. Safely resuming neglected tropical disease control activities during COVID-19: Perspectives from Nigeria and Guinea. PLoS Negl Trop Dis. 2021;15(12):e0009904doi: 10.1371/journal.pntd.0009904.
McKay, S., Shu'aibu, J., Cissé, A., Knight, A., Abdullahi, F., Ibrahim, A., Madaki, S., Genovezos, C., McCoy, K., Downs, P., Kabore, A., Adamu, H., Gobir, I. B., Chaitkin, M., & Standley, C. J. (2021). Safely resuming neglected tropical disease control activities during COVID-19: Perspectives from Nigeria and Guinea. PLoS neglected tropical diseases, 15(12), e0009904. https://doi.org/10.1371/journal.pntd.0009904
McKay, Stephanie, et al. "Safely resuming neglected tropical disease control activities during COVID-19: Perspectives from Nigeria and Guinea." PLoS neglected tropical diseases vol. 15,12 (2021): e0009904. doi: https://doi.org/10.1371/journal.pntd.0009904
McKay S, Shu'aibu J, Cissé A, Knight A, Abdullahi F, Ibrahim A, Madaki S, Genovezos C, McCoy K, Downs P, Kabore A, Adamu H, Gobir IB, Chaitkin M, Standley CJ. Safely resuming neglected tropical disease control activities during COVID-19: Perspectives from Nigeria and Guinea. PLoS Negl Trop Dis. 2021 Dec 20;15(12):e0009904. doi: 10.1371/journal.pntd.0009904. eCollection 2021 Dec. PMID: 34928945.
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Immunogenetic Association Underlying Severe COVID-19.

Vaccines

McCoy K, Peterson A, Tian Y, Sang Y.
PMID: 33233531
Vaccines (Basel). 2020 Nov 20;8(4). doi: 10.3390/vaccines8040700.

SARS-CoV2 has caused the current pandemic of new coronavirus disease 2019 (COVID-19) worldwide. Clinical outcomes of COVID-19 illness range broadly from asymptotic and mild to a life-threatening situation. This casts uncertainties for defining host determinants underlying the disease severity....

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McCoy K, Peterson A, Tian Y, et al. Immunogenetic Association Underlying Severe COVID-19. Vaccines (Basel). 2020;8(4)doi: 10.3390/vaccines8040700.
McCoy, K., Peterson, A., Tian, Y., & Sang, Y. (2020). Immunogenetic Association Underlying Severe COVID-19. Vaccines, 8(4), . https://doi.org/10.3390/vaccines8040700
McCoy, Kendall, et al. "Immunogenetic Association Underlying Severe COVID-19." Vaccines vol. 8,4 (2020). doi: https://doi.org/10.3390/vaccines8040700
McCoy K, Peterson A, Tian Y, Sang Y. Immunogenetic Association Underlying Severe COVID-19. Vaccines (Basel). 2020 Nov 20;8(4). doi: 10.3390/vaccines8040700. PMID: 33233531; PMCID: PMC7711778.
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Detecting change in community participation with the Enfranchisement scale of the community participation indicators.

Clinical rehabilitation

Kersey J, Terhorst L, Hammel J, Baum C, Toglia J, O'Dell MW, Heinemann AW, McCue M, Skidmore ER.
PMID: 34723687
Clin Rehabil. 2021 Nov 01;2692155211052188. doi: 10.1177/02692155211052188. Epub 2021 Nov 01.

OBJECTIVE: This study determined the sensitivity to change of the Enfranchisement scale of the Community Participation Indicators in people with stroke.DATA SOURCES: We analyzed data from two studies of participants with stroke: an intervention study and an observational study.MAIN...

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Kersey J, Terhorst L, Hammel J, et al. Detecting change in community participation with the Enfranchisement scale of the community participation indicators. Clin Rehabil. 2021;2692155211052188doi: 10.1177/02692155211052188.
Kersey, J., Terhorst, L., Hammel, J., Baum, C., Toglia, J., O'Dell, M. W., Heinemann, A. W., McCue, M., & Skidmore, E. R. (2021). Detecting change in community participation with the Enfranchisement scale of the community participation indicators. Clinical rehabilitation, 2692155211052188. https://doi.org/10.1177/02692155211052188
Kersey, Jessica, et al. "Detecting change in community participation with the Enfranchisement scale of the community participation indicators." Clinical rehabilitation vol. (2021): 2692155211052188. doi: https://doi.org/10.1177/02692155211052188
Kersey J, Terhorst L, Hammel J, Baum C, Toglia J, O'Dell MW, Heinemann AW, McCue M, Skidmore ER. Detecting change in community participation with the Enfranchisement scale of the community participation indicators. Clin Rehabil. 2021 Nov 01;2692155211052188. doi: 10.1177/02692155211052188. Epub 2021 Nov 01. PMID: 34723687.
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An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation.

Nature plants

Sigman MJ, Panda K, Kirchner R, McLain LL, Payne H, Peasari JR, Husbands AY, Slotkin RK, McCue AD.
PMID: 34750500
Nat Plants. 2021 Nov;7(11):1461-1474. doi: 10.1038/s41477-021-01008-7. Epub 2021 Nov 08.

In mammals and plants, cytosine DNA methylation is essential for the epigenetic repression of transposable elements and foreign DNA. In plants, DNA methylation is guided by small interfering RNAs (siRNAs) in a self-reinforcing cycle termed RNA-directed DNA methylation (RdDM)....

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Sigman MJ, Panda K, Kirchner R, et al. An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation. Nat Plants. 2021;7(11):1461-1474doi: 10.1038/s41477-021-01008-7.
Sigman, M. J., Panda, K., Kirchner, R., McLain, L. L., Payne, H., Peasari, J. R., Husbands, A. Y., Slotkin, R. K., & McCue, A. D. (2021). An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation. Nature plants, 7(11), 1461-1474. https://doi.org/10.1038/s41477-021-01008-7
Sigman, Meredith J, et al. "An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation." Nature plants vol. 7,11 (2021): 1461-1474. doi: https://doi.org/10.1038/s41477-021-01008-7
Sigman MJ, Panda K, Kirchner R, McLain LL, Payne H, Peasari JR, Husbands AY, Slotkin RK, McCue AD. An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation. Nat Plants. 2021 Nov;7(11):1461-1474. doi: 10.1038/s41477-021-01008-7. Epub 2021 Nov 08. PMID: 34750500; PMCID: PMC8592841.
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Draft Genome Sequence of Agrobacterium fabrum Strain 1D1104.

Microbiology resource announcements

Huo N, Gu Y, McCue KF, Alabed D, Thomson JG.
PMID: 34854699
Microbiol Resour Announc. 2021 Dec 02;10(48):e0099621. doi: 10.1128/MRA.00996-21. Epub 2021 Dec 02.

This work reports the draft genome sequence of Agrobacterium fabrum strain 1D1104. The assembled genome is composed of a 2,774,783-bp circular chromosome, a 2,110,112-bp linear chromosome, an AT plasmid of 133,577 bp, and four unassembled contigs of 5,389,544 bp,...

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Huo N, Gu Y, McCue KF, et al. Draft Genome Sequence of Agrobacterium fabrum Strain 1D1104. Microbiol Resour Announc. 2021;10(48):e0099621doi: 10.1128/MRA.00996-21.
Huo, N., Gu, Y., McCue, K. F., Alabed, D., & Thomson, J. G. (2021). Draft Genome Sequence of Agrobacterium fabrum Strain 1D1104. Microbiology resource announcements, 10(48), e0099621. https://doi.org/10.1128/MRA.00996-21
Huo, Naxin, et al. "Draft Genome Sequence of Agrobacterium fabrum Strain 1D1104." Microbiology resource announcements vol. 10,48 (2021): e0099621. doi: https://doi.org/10.1128/MRA.00996-21
Huo N, Gu Y, McCue KF, Alabed D, Thomson JG. Draft Genome Sequence of Agrobacterium fabrum Strain 1D1104. Microbiol Resour Announc. 2021 Dec 02;10(48):e0099621. doi: 10.1128/MRA.00996-21. Epub 2021 Dec 02. PMID: 34854699; PMCID: PMC8638575.
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"Adopt-a-Tissue" Initiative Advances Efforts to Identify Tissue-Specific Histone Marks in the Mare.

Frontiers in genetics

Kingsley NB, Hamilton NA, Lindgren G, Orlando L, Bailey E, Brooks S, McCue M, Kalbfleisch TS, MacLeod JN, Petersen JL, Finno CJ, Bellone RR.
PMID: 33841506
Front Genet. 2021 Mar 26;12:649959. doi: 10.3389/fgene.2021.649959. eCollection 2021.

No abstract available.

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Kingsley NB, Hamilton NA, Lindgren G, et al. "Adopt-a-Tissue" Initiative Advances Efforts to Identify Tissue-Specific Histone Marks in the Mare. Front Genet. 2021;12:649959doi: 10.3389/fgene.2021.649959.
Kingsley, N. B., Hamilton, N. A., Lindgren, G., Orlando, L., Bailey, E., Brooks, S., McCue, M., Kalbfleisch, T. S., MacLeod, J. N., Petersen, J. L., Finno, C. J., & Bellone, R. R. (2021). "Adopt-a-Tissue" Initiative Advances Efforts to Identify Tissue-Specific Histone Marks in the Mare. Frontiers in genetics, 12649959. https://doi.org/10.3389/fgene.2021.649959
Kingsley, N B, et al. ""Adopt-a-Tissue" Initiative Advances Efforts to Identify Tissue-Specific Histone Marks in the Mare." Frontiers in genetics vol. 12 (2021): 649959. doi: https://doi.org/10.3389/fgene.2021.649959
Kingsley NB, Hamilton NA, Lindgren G, Orlando L, Bailey E, Brooks S, McCue M, Kalbfleisch TS, MacLeod JN, Petersen JL, Finno CJ, Bellone RR. "Adopt-a-Tissue" Initiative Advances Efforts to Identify Tissue-Specific Histone Marks in the Mare. Front Genet. 2021 Mar 26;12:649959. doi: 10.3389/fgene.2021.649959. eCollection 2021. PMID: 33841506; PMCID: PMC8033197.
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Genetic Variants in Host Protein Disulfide Isomerase 2 (PDIA2) are Associated with Susceptibility to Chlamydia Trachomatis Infection.

Journal of the Association of Genetic Technologists

Zysk C, Williams S, Chavarria I, Wilson H, Balogun A, Jacobs E, Kaminski R, Foma BT, Johnson J, Lux W, McCoy K, Morales S, Sanchez G, Grubb P, Littlejohn M, Mize R, Moreno J, Pirtle C, Hendrix EC, Bennett KM.
PMID: 33293489
J Assoc Genet Technol. 2020;46(4):244-249.

OBJECTIVES: Objective: Host genetics can influence susceptibility to Chlamydia trachomatis infection. This study examined two genetic variants in human protein disulfide isomerase A2 (PDIA2), a member of a family of protein chaperones that participate in the chlamydial life cycle....

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Zysk C, Williams S, Chavarria I, et al. Genetic Variants in Host Protein Disulfide Isomerase 2 (PDIA2) are Associated with Susceptibility to Chlamydia Trachomatis Infection. J Assoc Genet Technol. 2020;46(4):244-249
Zysk, C., Williams, S., Chavarria, I., Wilson, H., Balogun, A., Jacobs, E., Kaminski, R., Foma, B. T., Johnson, J., Lux, W., McCoy, K., Morales, S., Sanchez, G., Grubb, P., Littlejohn, M., Mize, R., Moreno, J., Pirtle, C., Hendrix, E. C., & Bennett, K. M. (2020). Genetic Variants in Host Protein Disulfide Isomerase 2 (PDIA2) are Associated with Susceptibility to Chlamydia Trachomatis Infection. Journal of the Association of Genetic Technologists, 46(4), 244-249.
Zysk, Christopher, et al. "Genetic Variants in Host Protein Disulfide Isomerase 2 (PDIA2) are Associated with Susceptibility to Chlamydia Trachomatis Infection." Journal of the Association of Genetic Technologists vol. 46,4 (2020): 244-249.
Zysk C, Williams S, Chavarria I, Wilson H, Balogun A, Jacobs E, Kaminski R, Foma BT, Johnson J, Lux W, McCoy K, Morales S, Sanchez G, Grubb P, Littlejohn M, Mize R, Moreno J, Pirtle C, Hendrix EC, Bennett KM. Genetic Variants in Host Protein Disulfide Isomerase 2 (PDIA2) are Associated with Susceptibility to Chlamydia Trachomatis Infection. J Assoc Genet Technol. 2020;46(4):244-249. PMID: 33293489.
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Showing 193 to 203 of 203 entries